S. Tomar

发表

Structural and functional evolution of chitinase‐like proteins from plants

Pramod Kumar, Pravindra Kumar, A. Sharma, 2015, Proteomics.

Characterization of a cytoplasmic 2-Cys peroxiredoxin from Citrus sinensis and its potential role in protection from oxidative damage and wound healing.

Deena Nath Gupta, A. Sharma, S. Tomar, 2022, International journal of biological macromolecules.

Expression, purification, crystallization and preliminary crystallographic studies of cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase from Pandoraea pnomenusa B-356.

Pravindra Kumar, M. Sylvestre, D. Patil, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Alphavirus capsid protease inhibitors as potential antiviral agents for Chikungunya infection.

R. Kuhn, P. Kesari, S. Tomar, 2020, Antiviral research.

Inhibition of chikungunya virus by picolinate that targets viral capsid protein.

Pravindra Kumar, A. Saha, M. Parida, 2016, Virology.

Crystallization, high-resolution data collection and preliminary crystallographic analysis of Aura virus capsid protease and its complex with dioxane.

R. Kuhn, Pravindra Kumar, S. Tomar, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach

Y. Malik, S. Tomar, S. Choudhary, 2020, Frontiers in Immunology.

Advances in structure-assisted antiviral discovery for animal viral diseases

S. Tomar, Ravi Kumar, Supreeti Mahajan, 2019, Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries.

Crimean-Congo Hemorrhagic Fever Virus: Strategies to Combat with an Emerging Threat to Human

Pravindra Kumar, M. Narwal, S. Tomar, 2012 .

Glycan-dependent chikungunya viral infection divulged by antiviral activity of NAG specific chi-like lectin.

Neetu, Pravindra Kumar, S. Tomar, 2019, Virology.

Computational guided identification of novel potent inhibitors of N-terminal domain of nucleocapsid protein of severe acute respiratory syndrome coronavirus 2

V. Dalal, Pravindra Kumar, P. Dhankhar, 2020, Journal of biomolecular structure & dynamics.

Purification and Characterization of 2S Albumin from Seeds of Wrightia tinctoria Exhibiting Antibacterial and DNase Activity.

B. R. Gurjar, Neetu, M. Mishra, 2017, Protein and peptide letters.

Structure-function insights into chikungunya virus capsid protein: Small molecules targeting capsid hydrophobic pocket.

Pravindra Kumar, P. Kesari, S. Tomar, 2018, Virology.

Structure of Chorismate Mutase-like Domain of DAHPS from Bacillus subtilis Complexed with Novel Inhibitor Reveals Conformational Plasticity of Active Site

V. Kumar, Pravindra Kumar, M. Narwal, 2017, Scientific Reports.

Antiviral strategies targeting host factors and mechanisms obliging +ssRNA viral pathogens

Pravindra Kumar, S. Tomar, S. Choudhary, 2021, Bioorganic & Medicinal Chemistry.

Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.

V. Dalal, S. Ankri, S. Tomar, 2019 .

Structural insights into Entamoeba histolytica arginase and structure‐based identification of novel non‐amino acid based inhibitors as potential antiamoebic molecules

V. Dalal, S. Ankri, S. Tomar, 2019, The FEBS journal.

In-silico functional and structural annotation of hypothetical protein from Klebsiella pneumonia: A potential drug target.

V. Dalal, Pravindra Kumar, P. Dhankhar, 2022, Journal of molecular graphics & modelling.

Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach

Y. Malik, S. Tomar, S. Choudhary, 2020, Frontiers in Immunology.

Computational Guided Identification of Novel Potent Inhibitors of NTD-N-Protein of SARS-CoV-2

V. Dalal, Pravindra Kumar, P. Dhankhar, 2020 .

Chandipura Virus Utilizes the Prosurvival Function of RelA NF-κB for Its Propagation

Abhyudai Singh, P. K. Kushawaha, S. Tomar, 2019, Journal of Virology.

Structure–Function Relationship of Negative-Stranded Viral RNA Polymerases

S. Tomar, R. Kaur, V. Singh, 2019, Viral Polymerases.

Virus-host protein-protein interactions as molecular drug targets for arboviral infections

S. Tomar, Vishakha Singh, Mandar Bhutkar, 2022, Frontiers in Virology.

Multi-core-shell composite SnO2NPs@ZIF-8: potential antiviral agent and effective photocatalyst for waste-water treatment

R. Chandra, M. Nath, S. Tomar, 2019, Environmental Science and Pollution Research.

Conformer and pharmacophore based identification of peptidomimetic inhibitors of chikungunya virus nsP2 protease

Pravindra Kumar, Harvijay Singh, P. Kesari, 2017, Journal of biomolecular structure & dynamics.

Multi-target direct-acting SARS-CoV-2 antivirals against the nucleotide-binding pockets of virus-specific proteins

Ashutosh Kumar Singh, G. Mcinerney, Pravindra Kumar, 2022, Virology.

Alphavirus antivirals targeting RNA‐dependent RNA polymerase domain of nsP4 divulged using surface plasmon resonance

Pravindra Kumar, S. Tomar, M. Sharma, 2022, The FEBS journal.

Crystallization and preliminary X-ray diffraction analysis of the complex of Kunitz-type tamarind trypsin inhibitor and porcine pancreatic trypsin.

Preeti, Pravindra Kumar, A. Sharma, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purification, crystallization and preliminary crystallographic studies of a Kunitz-type proteinase inhibitor from tamarind (Tamarindus indica) seeds.

Pravindra Kumar, A. Sharma, D. Patil, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Isolation, purification, crystallization and preliminary crystallographic studies of chitinase from tamarind (Tamarindus indica) seeds.

Pravindra Kumar, A. Sharma, Manali Datta, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purification, crystallization and preliminary X-ray diffraction studies of disintegrin (schistatin) from saw-scaled viper (Echis carinatus).

T. Singh, V. Chandra, S. Tomar, 2001, Acta crystallographica. Section D, Biological crystallography.

Drug-Repurposing Approach To Combat Staphylococcus aureus: Biomolecular and Binding Interaction Study

D. Golemi-Kotra, V. Dalal, Pravindra Kumar, 2022, ACS omega.

Editorial: Emerging and re-emerging viral zoonoses

V. Uversky, S. Lau, S. Tomar, 2022, Frontiers in Microbiology.

Selective Estrogen Receptor Modulators Limit Alphavirus Infection by Targeting the Viral Capping Enzyme nsP1

S. Tomar, S. Basak, S. Choudhary, 2021, bioRxiv.

Evaluation of the Antiviral Potential of Halogenated Dihydrorugosaflavonoids and Molecular Modeling with nsP3 Protein of Chikungunya Virus (CHIKV)

S. Tomar, R. Rani, P. Srivastava, 2019, ACS omega.

Crystal structure and activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease revealed new allosteric sites for antiviral therapies

Pravindra Kumar, S. Tomar, R. Rani, 2022, bioRxiv.

Elucidation of the antiviral mechanism of natural therapeutic molecules Herbacetin and Caffeic acid phenethyl ester against Chikungunya and Dengue virus

Pravindra Kumar, S. Tomar, D. Sircar, 2022, bioRxiv.

Structural and Biochemical Analyses Reveal that Chlorogenic Acid Inhibits the Shikimate Pathway

Pravindra Kumar, S. Tomar, Aditya Dev, 2020, Journal of Bacteriology.

RNA-Dependent RNA Polymerase of Alphaviruses

S. Tomar, R. Mudgal, Akshay Pareek, 2019, Viral Polymerases.

Multifunctional inhibitors of SARS-CoV-2 by MM/PBSA, essential dynamics, and molecular dynamic investigations

V. Dalal, Pravindra Kumar, Monica Sharma, 2021, Journal of Molecular Graphics and Modelling.

MD simulation and MM/PBSA identifies phytochemicals as bifunctional inhibitors of SARS-CoV-2

J. K. Mahto, Pravindra Kumar, Monica Sharma, 2021, Journal of biomolecular structure & dynamics.

In vitro metal catalyzed oxidative stress in DAH7PS: Methionine modification leads to structure destabilization and induce amorphous aggregation.

Pravindra Kumar, A. Sharma, Vijay Kumar, 2018, International journal of biological macromolecules.

Chimeric chikungunya virus-like particles with surface exposed SARS-CoV-2 RBD elicits potent immunogenic responses in mice

Manidipa Banerjee, Pravindra Kumar, S. Tomar, 2023, bioRxiv.

Evolutionary and codon usage preference insights into spike glycoprotein of SARS-CoV-2

Kam Y. J. Zhang, R. Tiwari, K. Dhama, 2020, Briefings Bioinform..

Surface decorated reporter-tagged chikungunya virus-like particles for clinical diagnostics and identification of virus entry inhibitors.

R. Kuhn, Manidipa Banerjee, S. Tomar, 2023, Virology.

Chikungunya virus titration, detection and diagnosis using N-Acetylglucosamine (GlcNAc) specific lectin based virus capture assay.

Pravindra Kumar, S. Tomar, S. Choudhary, 2021, Virus research.

Chikungunya virus inhibition by peptidomimetic inhibitors targeting virus-specific cysteine protease.

M. Narwal, Harvijay Singh, S. Tomar, 2018, Biochimie.

Molecular insights into substrate recognition and catalysis by phthalate dioxygenase from Comamonas testosteroni

J. K. Mahto, Pravindra Kumar, A. Sharma, 2021, The Journal of biological chemistry.

Discovery of anti-SARS-CoV-2 molecules using structure-assisted repurposing approach targeting N-protein

Ashutosh Kumar Singh, Pravindra Kumar, S. Tomar, 2022 .

Catalytic Core of Alphavirus Nonstructural Protein nsP4 Possesses Terminal Adenylyltransferase Activity

R. Kuhn, Janet L. Smith, R. Hardy, 2006, Journal of Virology.

Development of an ELISA assay for screening inhibitors against divalent metal ion dependent alphavirus capping enzyme.

M. Narwal, S. Tomar, R. Kaur, 2018, Virus research.

Development of nsP2 protease based cell free high throughput screening assay for evaluation of inhibitors against emerging Chikungunya virus

A. Shrivastava, A. Saha, M. Parida, 2018, Scientific Reports.

Kinetic characterization of trans-proteolytic activity of Chikungunya virus capsid protease and development of a FRET-based HTS assay

Pravindra Kumar, M. Parida, S. Tomar, 2015, Scientific Reports.

Crystal Structure of Aura Virus Capsid Protease and Its Complex with Dioxane: New Insights into Capsid-Glycoprotein Molecular Contacts

Preeti, R. Kuhn, Pravindra Kumar, 2012, PloS one.

Inhibition of Chikungunya virus by an adenosine analog targeting the SAM‐dependent nsP1 methyltransferase

S. Tomar, Supreeti Mahajan, R. Mudgal, 2019, FEBS letters.

Heterologous production, purification and characterization of enzymatically active Sindbis virus nonstructural protein nsP1.

R. Kuhn, Janet L. Smith, M. Narwal, 2011, Protein expression and purification.

Structural Insight into DFMO Resistant Ornithine Decarboxylase from Entamoeba histolytica: An Inkling to Adaptive Evolution

Preeti, R. Madhubala, Pravindra Kumar, 2013, PloS one.

Structural basis for dual inhibitory role of tamarind Kunitz inhibitor (TKI) against factor Xa and trypsin

Pravindra Kumar, A. Sharma, D. Patil, 2012, The FEBS journal.

Emerging SARS-CoV-2 Variants: Genetic Variability and Clinical Implications

Pravindra Kumar, S. Tomar, S. Choudhary, 2021, Current Microbiology.

Characterization of dye-decolorizing peroxidase from Bacillus subtilis.

B. R. Gurjar, V. Dalal, J. K. Mahto, 2020, Archives of biochemistry and biophysics.

In silico and proteomic analysis of protein methyltransferase CheR from Bacillus subtilis.

Pawan Gupta, Vemika Chandra, S. Tomar, 2015, International journal of biological macromolecules.

Biochemical, Mutational and In Silico Structural Evidence for a Functional Dimeric Form of the Ornithine Decarboxylase from Entamoeba histolytica

Preeti, R. Madhubala, Pravindra Kumar, 2012, PLoS neglected tropical diseases.

Crystal structure of schistatin, a disintegrin homodimer from saw-scaled viper (Echis carinatus) at 2.5 A resolution.

Sujata Sharma, T. Singh, P. Kaur, 2004, Journal of molecular biology.

trans-Protease Activity and Structural Insights into the Active Form of the Alphavirus Capsid Protease

R. Kuhn, Pravindra Kumar, S. Tomar, 2014, Journal of Virology.

Green synthesis of nanometal impregnated biomass - antiviral potential.

S. N. Reddy, S. Tomar, S. Choudhary, 2020, Materials science & engineering. C, Materials for biological applications.

Discovery of anti-SARS-CoV-2 molecules using structure-assisted repurposing approach targeting N-protein

Ashutosh Kumar Singh, Pravindra Kumar, S. Tomar, 2023, bioRxiv.

Evaluation of antiviral activity of piperazine against Chikungunya virus targeting hydrophobic pocket of alphavirus capsid protein

Pravindra Kumar, A. Saha, M. Parida, 2017, Antiviral research.

Chapter 5 – Structure and Function of Alphavirus Proteases

S. Tomar, Megha Aggarwal, 2017 .

Crystal structure and activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease revealed new allosteric sites for antiviral therapies

Pravindra Kumar, S. Tomar, R. Rani, 2023, bioRxiv.

Sustainability of maize-wheat cropping system by different legume intercropping and nitrogen level treatments on light distribution, soil temperature and crop productivity

Purushottam, S. Singh, B. Singh, 2014 .

Prospects for mucosal vaccine: shutting the door on SARS-CoV-2

S. Tomar, Sanketkumar Nehul, R. Mudgal, 2020, Human vaccines & immunotherapeutics.

Structural Investigation of a Novel N-Acetyl Glucosamine Binding Chi-Lectin Which Reveals Evolutionary Relationship with Class III Chitinases

S. Kundu, Pravindra Kumar, A. Sharma, 2013, PloS one.

Biochemical and biophysical insights into the metal binding spectrum and bioactivity of arginase of Entamoeba histolytica.

Harvijay Singh, S. Tomar, A. Malik, 2018, Metallomics : integrated biometal science.

Crystal Structure of FmtA from Staphylococcus aureus at 2.58 A

D. Golemi-Kotra, V. Dalal, Pravindra Kumar, 2019 .

Flavivirus Protease: An Antiviral Target

S. Tomar, B. Fatma, R. Mudgal, 2017 .

Structural, Functional and Evolutionary Aspects of Seed Globulins.

B. R. Gurjar, Neetu, Pravindra Kumar, 2017, Protein and peptide letters.

Crystal structure of chikungunya virus nsP2 cysteine protease reveals a putative flexible loop blocking its active site.

R. Kuhn, Pravindra Kumar, M. Narwal, 2018, International journal of biological macromolecules.

A novel function for globulin in sequestering plant hormone: Crystal structure of Wrightia tinctoria 11S globulin in complex with auxin

Neetu, Pravindra Kumar, A. Sharma, 2017, Scientific Reports.

Design, synthesis, antiviral evaluation, and In silico studies of acrylamides targeting nsP2 from Chikungunya virus.

Letícia Anderson, Ê. J. Bassi, S. Tomar, 2023, European journal of medicinal chemistry.

Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS-COV-2 targeting virus-specific enzymes

Ashutosh Kumar Singh, Pravindra Kumar, S. Tomar, 2023, bioRxiv.

Targeting host protein G3BP1 for the discovery of novel antiviral inhibitors against the Chikungunya virus

Ashutosh Kumar Singh, G. Mcinerney, S. Tomar, 2023, bioRxiv.

Revealing and evaluation of antivirals targeting multiple druggable sites of RdRp complex in SARS-CoV-2

Pravindra Kumar, S. Tomar, R. Rani, 2023, bioRxiv.

Characterization of recombinant pumpkin 2S albumin and mutation studies to unravel potential DNA/RNA binding site.

Deena Nath Gupta, V. Dalal, Pravindra Kumar, 2021, Biochemical and biophysical research communications.

Mechanistic and thermodynamic characterization of antivirals targeting druggable pocket of SARS-CoV-2 nucleocapsid

Ashutosh Kumar Singh, Pravindra Kumar, S. Tomar, 2023, bioRxiv.

Evaluation of nucleic acid binding site of SARS-CoV-2 nucleocapsid as a potential antiviral target using small molecule inhibitors

Ashutosh Kumar Singh, Pravindra Kumar, S. Tomar, 2023, bioRxiv.

Cellular uptake of metal oxide-based nanocomposites and targeting of chikungunya virus replication protein nsP3.

M. Nath, S. Tomar, R. Rani, 2023, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Identification and evaluation of antiviral potential of thymoquinone, a natural compound targeting Chikungunya virus capsid protein.

S. Tomar, Ravi Kumar, Sanketkumar Nehul, 2021, Virology.

Elucidation of antiviral mechanisms of natural therapeutic molecules Herbacetin and Caffeic acid phenethyl ester against chikungunya and dengue virus

Pravindra Kumar, S. Tomar, D. Sircar, 2023, bioRxiv.

Biochemical Studies and Ligand-bound Structures of Biphenyl Dehydrogenase from Pandoraea pnomenusa Strain B-356 Reveal a Basis for Broad Specificity of the Enzyme*

M. Mohammadi, Pravindra Kumar, M. Sylvestre, 2011, The Journal of Biological Chemistry.

Deciphering the enigma of missing DNA binding domain of LacI family transcription factors.

J. K. Mahto, Pravindra Kumar, A. Sharma, 2021, Archives of biochemistry and biophysics.

Conformer and pharmacophore based identification of peptidomimetic inhibitors of chikungunya virus nsP2 protease

Pravindra Kumar, Harvijay Singh, P. Kesari, 2017, Journal of biomolecular structure & dynamics.

Crystal structure of pentapeptide-independent chemotaxis receptor methyltransferase (CheR) reveals idiosyncratic structural determinants for receptor recognition.

Pravindra Kumar, S. Tomar, S. Dhindwal, 2016, Journal of structural biology.

Structural basis for dual inhibitory role of tamarind Kunitz inhibitor (TKI) against factor Xa and trypsin

Pravindra Kumar, A. Sharma, D. Patil, 2012, The FEBS journal.

In Silico sequence analysis and molecular modeling of the three-dimensional structure of DAHP synthase from Pseudomonas fragi

S. Tomar, S. Dhindwal, Satya Tapas, 2011, Journal of molecular modeling.

Identification and evaluation of potential inhibitor molecules against TcyA from Candidatus Liberibacter asiaticus.

P. Kumar, V. Dalal, Pravindra Kumar, 2023, Journal of Structural Biology.

Comparative Analysis of Inhibitor Binding to Peroxiredoxins from Candidatus Liberibacter asiaticus and Its Host Citrus sinensis.

Deena Nath Gupta, S. Tomar, R. Rani, 2023, Applied biochemistry and biotechnology.

Repurposing an Ancient Protein Core Structure: Structural Studies on FmtA, a Novel Esterase of Staphylococcus aureus.

V. Dalal, Pravindra Kumar, S. Tomar, 2019, Journal of molecular biology.

Sulisobenzone is a potent inhibitor of the global transcription factor Cra.

Pravindra Kumar, S. Tomar, M. Katiki, 2023, Journal of structural biology.

Enhancing affinity of neutralizing SARS-CoV-2 nanobody through facile structure-guided mutations in CDRs

Pravindra Kumar, S. Tomar, S. Choudhary, 2024, bioRxiv.