Conor R Caffrey

发表

Chemotherapy of schistosomiasis: present and future.

C. Caffrey, Conor R Caffrey, 2007, Current opinion in chemical biology.

Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni*

Jindrich Fanfrlík, Jana Váchová, J. McKerrow, 2011, The Journal of Biological Chemistry.

Schistosoma comparative genomics: integrating genome structure, parasite biology and anthelmintic discovery.

Denis M Larkin, Karl F Hoffmann, Alex Loukas, 2011, Trends in parasitology.

Mapping the pro-peptide of the Schistosoma mansoni cathepsin B1 drug target: modulation of inhibition by heparin and design of mimetic inhibitors.

J. Vondrášek, C. Caffrey, Conor R Caffrey, 2011, ACS chemical biology.

Substrate specificity of schistosome versus human legumain determined by P1-P3 peptide libraries.

Matthew Bogyo, Harold Chapman, M. Bogyo, 2002, Molecular and biochemical parasitology.

SmCB2, a novel tegumental cathepsin B from adult Schistosoma mansoni.

Andreas Ruppel, M. Sajid, J. McKerrow, 2002, Molecular and biochemical parasitology.

A Multienzyme Network Functions in Intestinal Protein Digestion by a Platyhelminth Parasite*

Jan Dvorák, Mahmoud Bahgat, J. Dvorak, 2006, Journal of Biological Chemistry.

Schistosomiasis: from drug deployment to drug development

C. Caffrey, W. Secor, Conor R Caffrey, 2011, Current opinion in infectious diseases.

Hemoglobin digestion in blood-feeding ticks: mapping a multipeptidase pathway by functional proteomics.

Matthew Bogyo, Daniel Sojka, M. Bogyo, 2009, Chemistry & biology.

Peptidyl allyl sulfones: a new class of inhibitors for clan CA cysteine proteases.

J. McKerrow, C. Caffrey, J. Powers, 2004, Bioorganic & medicinal chemistry.

Chapter 4. Peptidases of trematodes.

Jan Dvorák, Petr Horák, John P Dalton, 2009, Advances in parasitology.

Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design*

Jennifer Legac, Iain D Kerr, C. Craik, 2009, The Journal of Biological Chemistry.

Schistosomiasis Mansoni: Novel Chemotherapy Using a Cysteine Protease Inhibitor

M. Sajid, J. McKerrow, C. Caffrey, 2007, PLoS medicine.

Homology modeling and SAR analysis of Schistosoma japonicum cathepsin D (SjCD) with statin inhibitors identify a unique active site steric barrier with potential for the design of specific inhibitors

Pavel Majer, Jirí Vondrásek, J. Konvalinka, 2005, Biological chemistry.

Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi.

Kelly Chibale, Jiri Gut, J. Gut, 2004, Journal of medicinal chemistry.

High Throughput and Computational Repurposing for Neglected Diseases

Sean Ekins, Kimberley M. Zorn, Carolina Horta Andrade, 2018, Pharmaceutical Research.

Aza-peptidyl Michael acceptor and epoxide inhibitors--potent and selective inhibitors of Schistosoma mansoni and Ixodes ricinus legumains (asparaginyl endopeptidases).

Jan Dvorák, Fanuel Muindi, Daniel Sojka, 2009, Journal of medicinal chemistry.

Recent initiatives and strategies to developing new drugs for tropical parasitic diseases

C. Caffrey, D. Steverding, Conor R Caffrey, 2008, Expert opinion on drug discovery.

Differential use of protease families for invasion by schistosome cercariae.

Jan Dvorák, Katalin F Medzihradszky, Patricia C Babbitt, 2008, Biochimie.

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Manuel Llinás, George Papadatos, Sundari Suresh, 2016, PLoS pathogens.

Blood 'n' guts: an update on schistosome digestive peptidases.

M. Sajid, J. McKerrow, C. Caffrey, 2004, Trends in parasitology.

Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

Michele Connelly, Anang A Shelat, R Kiplin Guy, 2008, Journal of medicinal chemistry.