Laurence E. Cheng

发表

Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell death

B. Nelson, P. Greenberg, Laurence E. Cheng, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease

J. Orange, R. Siegel, J. Ashwell, 2016, Proceedings of the National Academy of Sciences.

Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target

Troy E. Barger, H. Hsu, M. C. Teixeira dos Santos, 2021, Frontiers in Immunology.

CD8+ T cell responses: it's all downhill after their prime ...

J. Blattman, P. Greenberg, Laurence E. Cheng, 2002, Nature Immunology.

Functional redundancy of the Nur77 and Nor‐1 orphan steroid receptors in T‐cell apoptosis

F. Chan, A. Winoto, D. Cado, 1997, The EMBO journal.

CD8+ T Cell Tolerance to a Tumor-associated Antigen Is Maintained at the Level of Expansion Rather than Effector Function

M. Kalos, P. Greenberg, B. Carson, 2002, The Journal of experimental medicine.

and A receptor in activation-induced apoptosis . Regulation of the Nur 77 orphan steroid

B. Calnan, A. Winoto, Laurence E. Cheng, 1995 .

Murine B Cells Regulate Serum IgE Levels in a CD23-Dependent Manner

R. Locksley, Laurence E. Cheng, Zhi-En Wang, 2010, The Journal of Immunology.

Murine B Cells Regulate Serum IgE Levels in a CD23-Dependent Manner

R. Locksley, Laurence E. Cheng, Zhi-En Wang, 2010, The Journal of Immunology.

Allergic inflammation--innately homeostatic.

R. Locksley, Laurence E. Cheng, 2015, Cold Spring Harbor perspectives in biology.

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

R. Locksley, A. Chawla, Hong-Erh Liang, 2013, The Journal of experimental medicine.

Genetic analysis of basophil function in vivo

R. Locksley, Hong-Erh Liang, Jennifer K. Bando, 2011, Nature Immunology.

Safety and Biological Activity of Rozibafusp alfa, a Bispecific Inhibitor of Inducible Costimulator Ligand and B Cell Activating Factor, in Patients With Rheumatoid Arthritis: Results of a Phase 1b, Randomized, Double‐Blind, Placebo‐Controlled, Multiple Ascending Dose Study

Stanley B. Cohen, M. C. Teixeira dos Santos, B. Sullivan, 2022, ACR open rheumatology.

Dishing It Out to Allergies

M. Cabana, Laurence E. Cheng, 2015, Pediatrics.

Mast Cells Present Protrusions into Blood Vessels upon Tracheal Allergen Challenge in Mice

D. McDonald, P. Baluk, M. Krummel, 2015, PloS one.

Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome.

J. McCune, M. Heyman, D. Wara, 2009, Clinical immunology.

Type 2 innate lymphoid cells control eosinophil homeostasis

R. Locksley, A. Chawla, Jakob von Moltke, 2013, Nature.

Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E.

R. Locksley, M. Krummel, K. Hartmann, 2013, Immunity.

Selective Delivery of Augmented IL-2 Receptor Signals to Responding CD8+ T Cells Increases the Size of the Acute Antiviral Response and of the Resulting Memory T Cell Pool1

P. Greenberg, Laurence E. Cheng, 2002, The Journal of Immunology.

Pool CellResponse and of the Resulting Memory T AntiviralCells Increases the Size of the Acute T + Receptor Signals to Responding CD 8 Selective Delivery of Augmented IL-2

P. Greenberg, Laurence E. Cheng, 2002 .

A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multiple-Dose Study to Evaluate AMG 557 in Patients With Systemic Lupus Erythematosus and Active Lupus Arthritis

Z. Amoura, J. Merrill, F. Hiepe, 2018 .

TREC Newborn Screening Can Identify Patients with Leaky SCID and May Improve Outcome

J. Puck, Alice Y. Chan, M. Cowan, 2013 .

IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function

R. Locksley, Hong-Erh Liang, B. Sullivan, 2015, The Journal of experimental medicine.

Immunity Skin Mast Cells Probe Blood Vessels to Acquire IgE

R. Locksley, M. Krummel, K. Hartmann, 2012 .

P132 Design of an adaptive, phase 2, placebo-controlled, dose-ranging study to assess the efficacy and safety of AMG 570 in subjects with active SLE and inadequate response to standard of care therapy

R. Lenz, Tony Jiang, Laurence E. Cheng, 2020 .

Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E.

R. Locksley, M. Krummel, K. Hartmann, 2013, Immunity.

290 Development and first-in-human characterization of an ICOSL and BAFF bispecific inhibitor AMG 570 for SLE treatment

H. Hsu, B. Sullivan, J. Parnes, 2019, Abstracts.