C. Sucharov

发表

Micro-RNA expression in hypoplastic left heart syndrome.

A. Karimpour-Fard, C. Sucharov, Juliana Sucharov, 2015, Journal of cardiac failure.

Increased Phosphorylation‐Dependent Nuclear Export of Class II Histone Deacetylases in Failing Human Heart

T. McKinsey, M. Calalb, M. Bristow, 2009, Clinical and translational science.

Shuttling of HDAC5 in H9C2 cells regulates YY1 function through CaMKIV/PKD and PP2A.

L. Leinwand, S. Langer, M. Bristow, 2006, American journal of physiology. Cell physiology.

Dysregulation of cardiolipin biosynthesis in pediatric heart failure.

C. Sucharov, B. Stauffer, S. Miyamoto, 2014, Journal of molecular and cellular cardiology.

Phosphodiesterase Inhibition in Idiopathic Dilated Cardiomyopathy Age-Related Differences in Phosphodiesterase Activity and Effects of Chronic

M. Movsesian, C. Sucharov, B. Stauffer, 2015 .

β-Adrenergic receptor antagonism in mice: a model for pediatric heart disease.

C. Sucharov, B. Stauffer, S. Miyamoto, 2013, Journal of applied physiology.

Beta-adrenergic adaptation in paediatric idiopathic dilated cardiomyopathy.

C. Sucharov, K. Nunley, B. Stauffer, 2014, European heart journal.

Alteration of Cardiolipin Biosynthesis and Remodeling in Single Right Ventricle Congenital Heart Disease.

Anastacia M. Garcia, C. Sucharov, B. Stauffer, 2020, American journal of physiology. Heart and circulatory physiology.

Midkine’s Role in Cardiac Pathology

C. Sucharov, Kathleen C. Woulfe, K. Woulfe, 2017, Journal of cardiovascular development and disease.

Increased Myocyte Calcium Sensitivity in End-Stage Pediatric Dilated Cardiomyopathy.

L. Walker, Anastacia M. Garcia, C. Sucharov, 2019, American journal of physiology. Heart and circulatory physiology.

Differential Response to Heart Failure Medications in Children.

C. Sucharov, S. Miyamoto, Kathleen C. Woulfe, 2018, Progress in pediatric cardiology.

Phosphodiesterase Inhibition in Pediatric Heart Failure – Beneficial or Detrimental? Comparison to Adults with Heart failure

C. Sucharov, S. Nakano, 2013, jcvm.

Gene expression and β-adrenergic signaling are altered in hypoplastic left heart syndrome.

K. Stenmark, C. Sucharov, K. Nunley, 2014, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

miRNA expression in pediatric failing human heart.

Gloria Russell, C. Sucharov, K. Nunley, 2013, Journal of molecular and cellular cardiology.

CELF1 regulates gap junction integrity contributing to dilated cardiomyopathy.

C. Sucharov, Danielle A. Jeffrey, 2018, Non-coding RNA investigation.

A PDE3A Promoter Polymorphism Regulates cAMP-Induced Transcriptional Activity in Failing Human Myocardium.

Ian A. Carroll, T. McKinsey, Matthew R. G. Taylor, 2019, Journal of the American College of Cardiology.

Yin Yang 1 Is Increased in Human Heart Failure and Represses the Activity of the Human α-Myosin Heavy Chain Promoter*

C. Long, L. Leinwand, M. Bristow, 2003, Journal of Biological Chemistry.

Extracellular superoxide dismutase (EC-SOD) R213G variant reduces mitochondrial ROS and preserves mitochondrial function in bleomycin-induced lung injury: EC-SOD R213G variant and intracellular redox regulation.

James R. Roede, R. Bowler, H. Suliman, 2022, Advances in redox research.

β-adrenergic pathways in human heart failure

C. Sucharov, 2007 .

Anastacia M. Garcia, C. Galambos, C. Sucharov, 2017, The Journal of pediatrics.

Elamipretide Improves Mitochondrial Function in the Failing Human Heart

C. Sucharov, B. Stauffer, S. Miyamoto, 2019, JACC. Basic to translational science.

Role of p38MAPK in beta(2)AR-induced cardiomyopathy: at the heart of the matter?

C. Sucharov, 2007, Future cardiology.

Myocardial microRNAs associated with reverse remodeling in human heart failure.

J. Port, R. Quaife, A. Karimpour-Fard, 2017, JCI insight.

A beta1-adrenergic receptor CaM kinase II-dependent pathway mediates cardiac myocyte fetal gene induction.

C. Long, L. Leinwand, M. Bristow, 2006, American journal of physiology. Heart and circulatory physiology.

Cardiac Adenylyl Cyclase and Phosphodiesterase Expression Profiles Vary by Age, Disease, and Chronic Phosphodiesterase Inhibitor Treatment.

C. Sucharov, Juliana Sucharov, K. Nunley, 2017, Journal of cardiac failure.

Gene expression and heart failure

C. Sucharov, 2005, Expert review of cardiovascular therapy.

Localization of a transcription promoter within the second exon of the cytochrome P-450c27/25 gene for the expression of the major species of two-kilobase mRNA.

S. Addya, N. Avadhani, C. Sucharov, 1995, Biochemistry.

Circulating microRNAs differentiate Kawasaki Disease from infectious febrile illnesses in childhood.

A. Karimpour-Fard, S. Dominguez, P. Jone, 2020, Journal of molecular and cellular cardiology.

Integrated Analysis of miRNA-mRNA Interaction in Pediatric Dilated Cardiomyopathy

A. Karimpour-Fard, Lee S. Toni, M. Bristow, 2021, Pediatric Research.

Redistribution of EC‐SOD resolves bleomycin‐induced inflammation via increased apoptosis of recruited alveolar macrophages

Austin E. Gillen, R. Bowler, J. Hesselberth, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

MicroRNA dysregulation in lung injury: the role of the miR-26a/EphA2 axis in regulation of endothelial permeability.

E. Nozik-Grayck, K. Birukov, U. Kompella, 2018, American journal of physiology. Lung cellular and molecular physiology.

Fibrosis and Fibrotic Gene Expression in Pediatric and Adult Patients With Idiopathic Dilated Cardiomyopathy.

C. Galambos, C. Sucharov, B. Stauffer, 2017, Journal of cardiac failure.

Circulating microRNA as a biomarker for recovery in pediatric dilated cardiomyopathy.

K. Stenmark, A. Karimpour-Fard, C. Sucharov, 2015, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Transgenic over-expression of YY1 induces pathologic cardiac hypertrophy in a sex-specific manner.

T. McKinsey, Kimberly M. Demos-Davies, Gloria Russell, 2015, Biochemical and biophysical research communications.

YY1 protects cardiac myocytes from pathologic hypertrophy by interacting with HDAC5.

T. McKinsey, C. Sucharov, K. Dockstader, 2008, Molecular Biology of the Cell.

YY 1 Protects Cardiac Myocytes from Pathologic Hypertrophy by Interacting with HDAC 5

T. McKinsey, C. Sucharov, K. Dockstader, 2008 .

The Ku Protein Complex Interacts with YY1, Is Up-Regulated in Human Heart Failure, and Represses α Myosin Heavy-Chain Gene Expression

L. Leinwand, S. Helmke, S. Langer, 2004, Molecular and Cellular Biology.

The Ku Protein Complex Interacts with YY1, Is Up-Regulated in Human Heart Failure, and Represses α Myosin Heavy-Chain Gene Expression

L. Leinwand, S. Helmke, S. Langer, 2004, Molecular and Cellular Biology.

YY1 is increased in human heart failure and represses the activity of the human αMyHC promoter

C. Long, L. Leinwand, M. Bristow, 2003 .

A novel transcriptional initiator activity of the GABP factor binding ets sequence repeat from the murine cytochrome c oxidase Vb gene.

N. Avadhani, C. Sucharov, R. S. Carter, 1995, Gene expression.

Exosomes from pediatric dilated cardiomyopathy patients modulate a pathological response in cardiomyocytes.

C. Sucharov, Juliana Sucharov, B. Stauffer, 2017, American journal of physiology. Heart and circulatory physiology.

A POLYMORPHISM IN THE PDE3A GENE PROMOTER THAT PREVENTS CAMP-INDUCED INCREASES IN TRANSCRIPTIONAL ACTIVITY, AND MAY PROTECT AGAINST PDE3A INHIBITOR DRUG TOLERANCE.

Matthew R. G. Taylor, D. Slavov, M. Bristow, 2010 .

Phosphodiesterase-5 Is Elevated in Failing Single Ventricle Myocardium and Affects Cardiomyocyte Remodeling In Vitro

A. Karimpour-Fard, Anastacia M. Garcia, C. Sucharov, 2018, Circulation. Heart failure.

Amniotic Fluid microRNA in Severe Twin-Twin Transfusion Syndrome Cardiomyopathy—Identification of Differences and Predicting Demise

T. Crombleholme, B. Cuneo, A. Karimpour-Fard, 2022, Journal of cardiovascular development and disease.

EXPRESSION OF CARDIOLIPIN BIOSYNTHESIS AND REMODELING ENZYMES IN ADULT HEART FAILURE

C. Sucharov, B. Stauffer, G. Sparagna, 2013 .

Targeted delivery of YSA-functionalized and non-functionalized polymeric nanoparticles to injured pulmonary vasculature

E. Nozik-Grayck, U. Kompella, R. Good, 2018, Artificial cells, nanomedicine, and biotechnology.

Plasma microRNA and metabolic changes associated with pediatric acute respiratory distress syndrome: a prospective cohort study

P. Mourani, A. Karimpour-Fard, E. Nozik, 2022, Scientific Reports.

Basic Science and Experimental Study Micro-RNA Expression in Hypoplastic Left Heart Syndrome

A. Karimpour-Fard, C. Sucharov, Juliana Sucharov, 2015 .

Improved Detection of Circulating miRNAs in Serum and Plasma Following Rapid Heat/Freeze Cycling

A. Karimpour-Fard, Peter D. Mariner, C. Sucharov, 2018, MicroRNA.

Cardiac Transcriptome Remodeling and Impaired Bioenergetics in Single-Ventricle Congenital Heart Disease.

A. Karimpour-Fard, Anastacia M. Garcia, Lee S. Toni, 2023, JACC. Basic to translational science.

Adrenergic Receptor Signaling in Heart Failure

J. Port, M. Bristow, C. Sucharov, 2020 .

Chapter 10 – Activation of the Adrenergic Nervous System in Heart Failure

J. Port, M. Bristow, C. Sucharov, 2011 .

Circulating miRNAs in Pediatric Pulmonary Hypertension Show Promise as Biomarkers of Vascular Function

R. Shandas, V. Kheyfets, D. Ivy, 2017, Oxidative medicine and cellular longevity.

Temporal expression of miRNAs and mRNAs in a mouse model of myocardial infarction.

J. Port, L. Walker, P. Buttrick, 2011, Physiological genomics.

Role of MicroRNAs in Cardiovascular Disease: Therapeutic Challenges and Potentials

J. Port, C. Sucharov, J. Port, 2010, Journal of cardiovascular pharmacology.

Mini-review: Dysregulated microRNAs and long non-coding RNAs in cardiac development and pediatric heart failure.

Lee S. Toni, C. Sucharov, Frehiwet Hailu, 2020, American journal of physiology. Heart and circulatory physiology.

Molecular Pathways in Cardiomyopathies

C. Sucharov, B. Stauffer, S. Miyamoto, 2017 .

Optimization of phenol-chloroform RNA extraction

Anastacia M. Garcia, Lee S. Toni, C. Sucharov, 2018, MethodsX.

Circulating microRNAs as biomarkers in pediatric heart diseases

Anastacia M. Garcia, C. Sucharov, S. Miyamoto, 2018, Progress in Pediatric Cardiology.

Prevalence of Desmin Mutations in Dilated Cardiomyopathy

C. Long, L. Mestroni, P. Lavori, 2007, Circulation.

Fragile X trinucleotide repeats from a normal population in Rio de Janeiro, Brazil.

E. Rondinelli, C. Sucharov, R. Moura-Neto, 2004, Hereditas.

Brief Report Fragile X trinucleotide repeats from a normal population in Rio de Janeiro, Brazil

E. Rondinelli, Rosane Silva, C. Sucharov, 1999 .

86 Amniotic fluid microRNA profiles in twin-twin transfusion syndrome with and without severe cardiomyopathy

A. Karimpour-Fard, H. Galan, C. Sucharov, 2021 .

Yin Yang 1 represses α-myosin heavy chain gene expression in pathologic cardiac hypertrophy

C. Long, L. Leinwand, Peter D. Mariner, 2004 .

PGC-1alpha and ERRalpha target gene downregulation is a signature of the failing human heart.

S. Sihag, S. Cresci, Allie Li, 2009, Journal of molecular and cellular cardiology.

MicroRNA regulation post-bleomycin due to the R213G extracellular superoxide dismutase variant is predicted to suppress inflammatory and immune pathways.

E. Nozik-Grayck, A. Karimpour-Fard, Anastacia M. Garcia, 2020, Physiological genomics.

Amniotic fluid microRNA profiles in twin-twin transfusion syndrome with and without severe recipient cardiomyopathy.

B. Cuneo, A. Karimpour-Fard, H. Galan, 2021, American journal of obstetrics and gynecology.

R213G polymorphism in SOD3 protects against bleomycin-induced inflammation and attenuates induction of proinflammatory pathways.

R. Bowler, E. Nozik-Grayck, Philip D. Tatman, 2018, Physiological genomics.

Temporal analysis of mRNA and miRNA expression in transgenic mice overexpressing Arg- and Gly389 polymorphic variants of the β1-adrenergic receptor.

J. Port, S. Liggett, A. Karimpour-Fard, 2011, Physiological genomics.

MicroRNA-124 Controls the Proliferative, Migratory, and Inflammatory Phenotype of Pulmonary Vascular Fibroblasts

W. Seeger, S. Pullamsetti, T. McKinsey, 2014, Circulation research.

Sex Differences in Cardiomyocyte Connexin43 Expression

C. Sucharov, B. Stauffer, Rebecca D. Sobus, 2011, Journal of cardiovascular pharmacology.

Acute isoproterenol leads to age-dependent arrhythmogenesis in guinea pigs.

C. Sucharov, B. Stauffer, S. Miyamoto, 2018, American journal of physiology. Heart and circulatory physiology.

M. Movsesian, C. Sucharov, B. Stauffer, 2015, Circulation. Heart failure.

Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation

Brian A. Aguado, L. Leinwand, K. Anseth, 2019, Science Translational Medicine.

Big tau aggregation and the broken heart.

C. Sucharov, O. Nyarko, 2023, European heart journal.

miRNA expression in the failing human heart: functional correlates.

J. Port, M. Bristow, C. Sucharov, 2008, Journal of molecular and cellular cardiology.

Signal-Dependent Recruitment of BRD4 to Cardiomyocyte Super-Enhancers Is Suppressed by a MicroRNA.

Saptarsi M. Haldar, Charles Y. Lin, J. Bradner, 2016, Cell reports.

A novel genetic marker of decreased inflammation and improved survival after acute myocardial infarction

L. Bierut, J. Spertus, R. Bach, 2018, Basic Research in Cardiology.

Pediatric dilated cardiomyopathy hearts display a unique gene expression profile.

J. Cleveland, Philip D. Tatman, Matthew R. G. Taylor, 2017, JCI insight.

Molecular Changes in Children with Heart Failure Undergoing Left Ventricular Assist Device Therapy

C. Sucharov, B. Stauffer, S. Miyamoto, 2017, The Journal of pediatrics.

Circulating MicroRNAs Identify Early Phenotypic Changes in Sarcomeric Hypertrophic Cardiomyopathy

A. Karimpour-Fard, Carolyn Y. Ho, C. Sucharov, 2023, Circulation. Heart failure.

β-Adrenergic receptor stimulation and activation of protein kinase A protect against α1-adrenergic-mediated phosphorylation of protein kinase D and histone deacetylase 5.

T. McKinsey, M. Bristow, C. Sucharov, 2011, Journal of cardiac failure.

Serum circulating proteins from pediatric patients with dilated cardiomyopathy cause pathologic remodeling and cardiomyocyte stiffness

O. Sbaizero, Matthew R. G. Taylor, A. Karimpour-Fard, 2021, JCI insight.

Circulating cyclic adenosine monophosphate concentrations in milrinone treated paediatric patients after congenital heart surgery

M. Wempe, A. Karimpour-Fard, C. Sucharov, 2021, Cardiology in the Young.

The secretome as a biomarker and functional agent in heart failure

C. Sucharov, O. Nyarko, 2023, The journal of cardiovascular aging.

An extensive β1-adrenergic receptor gene signaling network regulates molecular remodeling in dilated cardiomyopathies

Ian A. Carroll, S. Liggett, Philip D. Tatman, 2023, JCI insight.

Myocardial Response to Milrinone in Single Right Ventricle Heart Disease.

C. Sucharov, S. Miyamoto, S. Nakano, 2016, The Journal of pediatrics.

Interaction between PPARA genotype and beta-blocker treatment influences clinical outcomes following acute coronary syndromes.

J. Spertus, M. Province, H. McLeod, 2008, Pharmacogenomics.

Circulating and Cardiac Tissue miRNAs in Children with Dilated Cardiomyopathy

S. Lipshultz, A. Karimpour-Fard, C. Sucharov, 2023, Journal of cardiovascular development and disease.

β-Adrenergic receptor antagonism in mice: a model for pediatric heart disease.

C. Sucharov, B. Stauffer, S. Miyamoto, 2013, Journal of applied physiology.

Temporal analysis of mRNA and miRNA expression in transgenic mice overexpressing Arg- and Gly389 polymorphic variants of the β1-adrenergic receptor.

A. Karimpour-Fard, C. Sucharov, K. Nunley, 2011, Physiological genomics.

Sex Differences in Cardiomyocyte Connexin43 Expression

C. Sucharov, B. Stauffer, Rebecca D. Sobus, 2011, Journal of cardiovascular pharmacology.

Cardiac Transcriptome Remodeling and Impaired Bioenergetics in Single-Ventricle Congenital Heart Disease.

A. Karimpour-Fard, Anastacia M. Garcia, Lee S. Toni, 2023, JACC. Basic to translational science.

MicroRNA-124 Controls the Proliferative, Migratory, and Inflammatory Phenotype of Pulmonary Vascular Fibroblasts

W. Seeger, S. Pullamsetti, T. McKinsey, 2014, Circulation research.

RESEARCH Integrative Cardiovascular Physiology and Pathophysiology Acute isoproterenol leads to age-dependent arrhythmogenesis in guinea pigs

C. Sucharov, Elisabeth K. Phillips, Cortney E. Wilson, 2022 .

Mitochondrial respiration is lower in the intrauterine growth‐restricted fetal sheep heart

P. Rozance, C. Sucharov, L. Knaub, 2024, The Journal of physiology.

Dysregulation of miRNA–mRNA expression in fetal growth restriction in a caloric restricted mouse model

A. Karimpour-Fard, C. Sucharov, J. Bardill, 2024, Scientific reports.

The pericardium forms as a distinct structure during heart formation

C. Mosimann, C. Sucharov, B. Peña, 2024, bioRxiv.

Circulating microRNA as a biomarker for recovery in pediatric dilated cardiomyopathy.

K. Stenmark, A. Karimpour-Fard, C. Sucharov, 2015, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.