Xiaotian Yuan

发表

Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players

C. Larsson, Dawei Xu, Xiaotian Yuan, 2019, Oncogene.

Human 15‐lipoxygenase‐1 is a regulator of dendriticcell spreading and podosome formation

M. Ekberg, M. Björkholm, Dawei Xu, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Association Between the Telomerase rs2736098_TT Genotype and a Lower Risk of Chronic Hepatitis B and Cirrhosis in Chinese Males

Dawei Xu, F. Wang, Chao Sun, 2017, Clinical and Translational Gastroenterology.

TERT rs2736100 genotypes are associated with differential risk of myeloproliferative neoplasms in Swedish and Chinese male patient populations

L. Saft, M. Björkholm, Dawei Xu, 2016, Annals of Hematology.

The association between the TERT rs2736100 AC genotype and reduced risk of upper tract urothelial carcinomas in a Han Chinese population

M. Björkholm, Dawei Xu, Xiaotian Yuan, 2016, Oncotarget.

The genetic difference between Western and Chinese urothelial cell carcinomas: infrequent FGFR3 mutation in Han Chinese patients

C. Liu, M. Björkholm, Dawei Xu, 2016, Oncotarget.

TERT promoter mutations and TERT mRNA but not FGFR3 mutations are urinary biomarkers in Han Chinese patients with urothelial bladder cancer.

C. Liu, Dawei Xu, Li Liu, 2015, The oncologist.

TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCR

C. Liu, M. Björkholm, Dawei Xu, 2014, Oncotarget.

GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma

M. Björkholm, Dawei Xu, Xiaotian Yuan, 2022, Journal of experimental & clinical cancer research : CR.

Telomere-related Markers for Cancer

Dawei Xu, Xiaotian Yuan, Mingkai Dai, 2020, Current topics in medicinal chemistry.

Telomerase reverse transcriptase promoter mutations in thyroid carcinomas: implications in precision oncology—a narrative review

Dawei Xu, Xiaotian Yuan, Tiantian Liu, 2020, Annals of translational medicine.

Longitudinal changes in leukocyte telomere length and mortality in elderly Swedish men

Dawei Xu, M. Hellénius, T. Cederholm, 2018, Aging.

Human 15-lipoxygenase-1 is a regulator of dendritic-cell spreading and podosome formation Human 15-lipoxygenase-1 is a regulator of dendritic-cell spreading and podosome formation.

M. Ekberg, M. Björkholm, Dawei Xu, 2016 .

Clinical characteristics and prognostic factors of patients with non-small cell lung cancer having HER2 alterations

Guobin Fu, Jing Zhao, Xiaotian Yuan, 2022, Journal of Cancer Research and Clinical Oncology.

The role of telomerase reverse transcriptase in human malignancies : genetic polymorphisms and promoter mutations

Xiaotian Yuan, 2017 .

Telomerase reverse transcriptase regulates DNMT3B expression/aberrant DNA methylation phenotype and AKT activation in hepatocellular carcinoma.

T. Ekström, M. Björkholm, Dawei Xu, 2018, Cancer letters.

Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes

M. Björkholm, Dawei Xu, Yujiao Wu, 2017, EBioMedicine.

GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression

C. Larsson, A. Stenman, Dawei Xu, 2018, Oncogene.

Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical Implications

Dawei Xu, Xiaotian Yuan, Tiantian Liu, 2016, Genes.

JAK2 inhibition in JAK2V617F-bearing leukemia cells enriches CD34+ leukemic stem cells that are abolished by the telomerase inhibitor GRN163L.

M. Björkholm, Dawei Xu, Xiaotian Yuan, 2020, Biochemical and biophysical research communications.

Thyroid carcinoma‐featured telomerase activation and telomere maintenance: Biology and translational/clinical significance

Ning Zhang, Dawei Xu, Xiaotian Yuan, 2022, Clinical and translational medicine.

TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends.

Dawei Xu, Xiaotian Yuan, Mingkai Dai, 2020, Cancer letters.

Downregulation and Hypermethylation of GABPB1 Is Associated with Aggressive Thyroid Cancer Features

C. Larsson, Shi-Yong Neo, Dawei Xu, 2022, Cancers.

Regulatory region mutations of TERT, PLEKHS1 and GPR126 genes as urinary biomarkers in upper tract urothelial carcinomas

M. Björkholm, Dawei Xu, Xiaotian Yuan, 2021, Journal of Cancer.

PLEKHS1 Over-Expression is Associated with Metastases and Poor Outcomes in Papillary Thyroid Carcinoma

C. Larsson, Dawei Xu, Xiaotian Yuan, 2020, Cancers.

GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer

Dawei Xu, Yujiao Wu, Chao Sun, 2019, Cell Death & Differentiation.

Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with Epigenetics

Dawei Xu, Xiaotian Yuan, 2019, International journal of molecular sciences.

The TERT locus genotypes of rs2736100-CC/CA and rs2736098-AA predict shorter survival in renal cell carcinoma.

C. Liu, M. Björkholm, Dawei Xu, 2019, Urologic oncology.

The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma

Dawei Xu, Chao Sun, Xiaotian Yuan, 2017, Oncotarget.

FKBP4 integrates FKBP4/Hsp90/IKK with FKBP4/Hsp70/RelA complex to promote lung adenocarcinoma progression via IKK/NF-κB signaling

Y. Jiao, B. Cui, Laicheng Wang, 2021, Cell Death & Disease.

Improvements and challenges of tissue preparation for spatial transcriptome analysis of skull base tumors

Yumin Wang, R. Fan, Hua Zhang, 2023, Heliyon.

Clinical characteristics and prognostic factors of patients with non-small cell lung cancer having HER2 alterations

Jing Zhao, Xiaotian Yuan, Wei Xu, 2022, Journal of Cancer Research and Clinical Oncology.