D. Smith

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Neuropharmacological Profile of Novel and Selective 5-HT6 Receptor Agonists: WAY-181187 and WAY-208466

Derek Cole, Qin Shan, A. Robichaud, 2008, Neuropsychopharmacology.

Evaluation of the Effects of Biofield Energy Healing Based Herbomineral Formulation on Various Biomarkers in Male Sprague Dawley Rats: Potential Role of the Trivedi Effect®

S. Jana, Jagdish Singh, M. Trivedi, 2017 .

Modulation of selective serotonin reuptake inhibitor and 5-HT1A antagonist activity in 8-aza-bicyclo[3.2.1]octane derivatives of 2,3-dihydro-1,4-benzodioxane.

R. Nilakantan, G. Stack, A. Gilbert, 2004, Bioorganic & medicinal chemistry letters.

Evaluation of Pro-Inflammatory Cytokines Expression in Mouse Splenocyte Cells After Incubation with the Biofield Energy Healing Based Herbomineral Formulation: Influence of the Trivedi Effect®

S. Jana, Jagdish Singh, M. Trivedi, 2016 .

Synthesis and biological evaluation of novel compounds within a class of 3-aminochroman derivatives with dual 5-HT1A receptor and serotonin transporter affinity.

B. Harrison, D. Huryn, C. Beyer, 2006, Journal of medicinal chemistry.

4-(2-Aminoethoxy)-N-(phenylsulfonyl)indoles as novel 5-HT6 receptor ligands.

B. Harrison, A. Robichaud, D. Huryn, 2005, Bioorganic & medicinal chemistry letters.

Studies toward the discovery of the next generation of antidepressants. Part 2: incorporating a 5-HT(1A) antagonist component into a class of serotonin reuptake inhibitors.

L. Schechter, D. Smith, P. Zhou, 2002, Bioorganic & medicinal chemistry letters.

Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT(6) agonists.

B. Harrison, A. Robichaud, C. Beyer, 2009, Bioorganic & medicinal chemistry.

Novel benzofuran derivatives with dual 5-HT1A receptor and serotonin transporter affinity.

B. Harrison, J. Ellingboe, L. Schechter, 2010, Bioorganic & medicinal chemistry letters.

Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinity.

B. Harrison, L. Schechter, D. Smith, 2006, Bioorganic & medicinal chemistry letters.

Studies towards the next generation of antidepressants. Part 4: derivatives of 4-(5-fluoro-1H-indol-3-yl)cyclohexylamine with affinity for the serotonin transporter and the 5-HT1A receptor.

Richard E Mewshaw, L. Schechter, D. Smith, 2005, Bioorganic & medicinal chemistry letters.

Novel aryloxy-8-azabicyclo[3.2.1]oct-3-enes with 5-HT transporter and 5-HT1A affinity.

T. Coleman, A. Gilbert, L. Schechter, 2004, Bioorganic & medicinal chemistry letters.

Studies Toward the Discovery of the Next Generation of Antidepressants. Part 2. Incorporating a 5‐HT1A Antagonist Component into a Class of Serotonin Reuptake Inhibitors.

L. Schechter, D. Smith, P. Zhou, 2002 .

5-Piperazinyl-3-sulfonylindazoles as potent and selective 5-hydroxytryptamine-6 antagonists.

T. Comery, A. Robichaud, Z. Hughes, 2010, Journal of medicinal chemistry.

Novel 1-(azacyclyl)-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines as 5-HT6 agonists and antagonists.

A. Robichaud, R. Magolda, H. Elokdah, 2007, Bioorganic & medicinal chemistry.

Identification of a series of benzoxazoles as potent 5-HT6 ligands.

T. Comery, A. Robichaud, L. Di, 2009, Bioorganic & medicinal chemistry letters.

1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-indoles as novel 5-HT6 receptor ligands.

B. Harrison, S. Antane, L. Schechter, 2004, Bioorganic & medicinal chemistry letters.

Synthesis, potency, and in vivo evaluation of 2-piperazin-1-ylquinoline analogues as dual serotonin reuptake inhibitors and serotonin 5-HT1A receptor antagonists.

B. Harrison, C. Beyer, G. Stack, 2009, Journal of medicinal chemistry.

Discovery of 5-arylsulfonamido-3-(pyrrolidin-2-ylmethyl)-1H-indole derivatives as potent, selective 5-HT6 receptor agonists and antagonists.

J. Ellingboe, G. Tawa, Guoming Zhang, 2005, Journal of medicinal chemistry.

Advances toward new antidepressants with dual serotonin transporter and 5-HT1A receptor affinity within a class of 3-aminochroman derivatives. Part 2.

B. Harrison, Minsheng Zhang, A. Failli, 2008, Journal of medicinal chemistry.

WAY‐100635 antagonist‐induced plasticity of 5‐HT1A receptors: regulatory differences between a stable cell line and an in vivo native system

S. Nawoschik, J. Dunlop, Jean Y Zhang, 2006, Journal of neurochemistry.

Impact of Consciousness Energy Healing Treatment on Herbomineral Formulation in Different Skin Health Parameters

M. Trivedi, A. Branton, D. Trivedi, 2017 .

Effects of the Energy of Consciousness Healing Treatment on Physical, Spectroscopic, Thermal and Behavioral Properties of Ashwagandha Root Extract

S. Jana, Jagdish Singh, M. Trivedi, 2017 .

Title Effects of the Energy of Consciousness Healing Treatment on Physical , Spectroscopic , Thermal and Behavioral Properties of Ashwagandha Root Extract Permalink

S. Jana, Jagdish Singh, M. Trivedi, 2017 .

Evaluation of Immunomodulatory Properties After Oral Administration of Biofield Energy Treated Test Formulation in Sprague Dawley Rats: Influence of the Trivedi Effect®

S. Jana, Jagdish Singh, M. Trivedi, 2017 .

Assessment of the Consciousness Energy Healing Treated Withania Somnifera (Ashwagandha) Root Extract Using LC-MS, GC-MS, and NMR Spectroscopy

S. Jana, Jagdish Singh, M. Trivedi, 2017 .

Characterization of a Novel M1 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator Radioligand, [3H]PT-1284

J. Edgerton, S. Grimwood, D. Smith, 2016, Molecular Pharmacology.

Studies toward the discovery of the next generation of antidepressants. 3. Dual 5-HT1A and serotonin transporter affinity within a class of N-aryloxyethylindolylalkylamines.

Xiaojie Shi, Richard E Mewshaw, L. Schechter, 2004, Journal of medicinal chemistry.

N1-arylsulfonyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives are potent and selective 5-HT6 receptor antagonists.

J. Ellingboe, Guoming Zhang, H. Mazandarani, 2005, Bioorganic & medicinal chemistry letters.

Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line.

S. Nawoschik, X. Khawaja, D. Smith, 2007, Journal of pharmacological and toxicological methods.

Studies toward the discovery of the next generation of antidepressants. Part 6: Dual 5-HT1A receptor and serotonin transporter affinity within a class of arylpiperazinyl-cyclohexyl indole derivatives.

B. Harrison, D. Huryn, L. Schechter, 2008, Bioorganic & medicinal chemistry.

The Metabotropic Glutamate Receptor 7 Allosteric Modulator AMN082: A Monoaminergic Agent in Disguise?

J. Dwyer, L. Di, A. Randall, 2011, Journal of Pharmacology and Experimental Therapeutics.

Characterization of Physicochemical, Thermal, Structural, and Behavioral Properties of Magnesium Gluconate After Treatment with the Energy of Consciousness

S. Jana, Jagdish Singh, M. Trivedi, 2017 .

Effect of the Energy of Consciousness (The Trivedi Effect®) on the Structural Properties and Isotopic Abundance Ratio of Magnesium Gluconate Using LC-MS and NMR Spectroscopy

S. Jana, Jagdish Singh, M. Trivedi, 2017 .

Structural Properties and Isotopic Abundance Ratio of Magnesium Gluconate Using LC-MS and NMR Spectroscopy

S. Jana, Jagdish Singh, M. Trivedi, 2017 .

Enhancing ketamine translational pharmacology via receptor occupancy normalization

Patrick E. Trapa, D. Smith, S. Osgood, 2014, Neuropharmacology.

5-Cyclic amine-3-arylsulfonylindazoles as novel 5-HT6 receptor antagonists.

T. Comery, Radka Graf, A. Robichaud, 2010, Journal of Medicinal Chemistry.

Identification of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT6 ligands.

T. Comery, A. Robichaud, L. Di, 2009, Bioorganic & medicinal chemistry letters.

Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT(6) antagonists.

T. Comery, A. Robichaud, L. Di, 2011, Bioorganic & medicinal chemistry.

Differential effects of regulator of G protein signaling (RGS) proteins on serotonin 5-HT1A, 5-HT2A, and dopamine D2 receptor-mediated signaling and adenylyl cyclase activity.

R. A. Hunt, Afshin Ghavami, K. Young, 2004, Cellular signalling.

Synthesis and biological evaluation of benzodioxanylpiperazine derivatives as potent serotonin 5-HT(1A) antagonists: the discovery of Lecozotan.

B. Harrison, D. Huryn, W. Childers, 2005, Journal of medicinal chemistry.

Correlating Efficacy in Rodent Cognition Models with In Vivo 5-HT 1 A Receptor Occupancy by a Novel Antagonist

Hughes, M. Day, T. Comery, 2008 .

3-(Arylsulfonyl)-1-(azacyclyl)-1H-indoles are 5-HT(6) receptor modulators.

B. Harrison, A. Robichaud, S. Antane, 2010, Bioorganic & medicinal chemistry letters.

1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-pyrrolopyridines are 5-HT(6) receptor ligands.

B. Harrison, A. Robichaud, S. Antane, 2009, Bioorganic & medicinal chemistry letters.

Correlating Efficacy in Rodent Cognition Models with in Vivo 5-Hydroxytryptamine1A Receptor Occupancy by a Novel Antagonist, (R)-N-(2-Methyl-(4-indolyl-1-piperazinyl)ethyl)-N-(2-pyridinyl)-cyclohexane Carboxamide (WAY-101405)

M. Day, T. Comery, S. Grauer, 2008, Journal of Pharmacology and Experimental Therapeutics.

Discovery of N1-(6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a potent, selective, and orally active 5-HT(6) receptor agonist.

K. Marquis, C. Beyer, J. Ellingboe, 2007, Journal of medicinal chemistry.

Effect of Biofield Energy Healing Based Herbomineral Formulation on Pro-Inflammatory Cytokines Expression in Biofield Treated Mouse Splenocyte Cells: Impact of the Trivedi Effect®

S. Jana, Jagdish Singh, M. Trivedi, 2018 .

1-Sulfonylindazoles as potent and selective 5-HT6 ligands.

Li Di, Edward H Kerns, Guo Ming Zhang, 2009, Bioorganic & medicinal chemistry letters.

Spinal Imidazoline Receptors Do Not Mediate the Antinociceptive Action of Intrathecal Clonidine in the Rat

D. Smith, P. Monroe, David J. Smith, 1995, Annals of the New York Academy of Sciences.

Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective alpha2A-adrenoceptor antagonism.

L. Leventhal, C. Beyer, J. Dwyer, 2010, The international journal of neuropsychopharmacology.

Novel pyridyl-fused 3-amino chroman derivatives with dual action at serotonin transporter and 5-HT1A receptor.

B. Harrison, G. Stack, L. Schechter, 2007, Bioorganic & medicinal chemistry letters.

Discovery and preclinical characterization of 1-methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): a highly potent, selective, and efficacious metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator.

J. Cianfrogna, A. Stepan, Daniel P. Walker, 2014, Journal of medicinal chemistry.

Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates.

J. Cianfrogna, A. Stepan, Daniel P. Walker, 2017, Journal of medicinal chemistry.

Conformationally constrained N1-arylsulfonyltryptamine derivatives as 5-HT6 receptor antagonists.

J. Ellingboe, G. Tawa, Guoming Zhang, 2005, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationship of novel lactam-fused chroman derivatives having dual affinity at the 5-HT(1A) receptor and the serotonin transporter.

B. Harrison, W. Childers, Zhongqi Shen, 2010, Bioorganic & medicinal chemistry letters.

Influence of the Consciousness Energy Healing Treatment on the Physicochemical, Spectral, Thermal and Behavioral Properties of Sodium Selenate

S. Jana, Jagdish Singh, M. Trivedi, 2017 .

A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands.

T. Comery, A. Robichaud, L. Di, 2008, Bioorganic & medicinal chemistry letters.

Bufotenine has a parachloroamphetamine-like action on the storage and release of serotonin in rat spinal cord synaptosomes

G. Williams, D. Smith, P. Monroe, 1994 .

Alterations in serotonin binding sites after 5,7-dihydroxytryptamine treatment in the rat spinal cord

D. Smith, L. Brown, David J. Smith, 1989, Neuroscience Letters.

Characterization of a Novel M1 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator Radioligand, [3H]PT-1284

J. Edgerton, S. Grimwood, D. Smith, 2016, Molecular Pharmacology.

5-HT3 receptors are not involved in the modulation of the K+-evoked release of [3H]5-HT from spinal cord synaptosomes of rat

D. J. Smith, G. Williams, D. Smith, 1992, Neuropharmacology.

Highly Potent , Selective , and E ffi cacious Metabotropic Glutamate Receptor 5 ( mGluR 5 ) Negative Allosteric Modulator

Ey, J. Cianfrogna, A. Stepan, 2014 .