Tim Künne

CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3.

Konstantin Severinov, Stan J. J. Brouns, Sander Bollen, 2012, Molecular cell.

Harnessing type I CRISPR–Cas systems for genome engineering in human cells

Leslie S. Edwards, Stan J. J. Brouns, David B. Nyer, 2019, Nature Biotechnology.

Degenerate target sites mediate rapid primed CRISPR adaptation

Jos Boekhorst, Stan J. J. Brouns, Peter C. Fineran, 2014, Proceedings of the National Academy of Sciences.

Cas3-Derived Target DNA Degradation Fragments Fuel Primed CRISPR Adaptation.

Stan J. J. Brouns, Maria Suarez-Diez, Misha Klein, 2016, Molecular cell.

Planting the seed: target recognition of short guide RNAs.

Stan J. J. Brouns, D. C. Swarts, Daan C Swarts, 2014, Trends in microbiology.