Shi Pey Wong

CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3.

Konstantin Severinov, Stan J. J. Brouns, Sander Bollen, 2012, Molecular cell.

The Biology of CRISPR-Cas: Backward and Forward

Emmanuelle Charpentier, E. Charpentier, Hagen Richter, 2018, Cell.