D. Panicali

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Role of Genes That Modulate Host Immune Responses in the Immunogenicity and Pathogenicity of Vaccinia Virus

M. Kuroda, M. Lifton, N. Letvin, 2005, Journal of Virology.

Two major DNA variants present in serially propagated stocks of the WR strain of vaccinia virus

S. Davis, E. Paoletti, D. Panicali, 1981, Journal of virology.

Insertion and deletion mutants of vaccinia virus.

M. Perkus, E. Paoletti, D. Panicali, 1986, Virology.

Analysis of c-erbB-2 expression in breast carcinomas with clinical follow-up.

S. Skates, A. Thor, H. Fingert, 1989, Cancer research.

Recombinant fowlpox viruses encoding the anchor-modified gp100 melanoma antigen can generate antitumor immune responses in patients with metastatic melanoma.

S. Rosenberg, P. Hwu, J. Yang, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Broadly reactive antibody-dependent cellular cytotoxic response to HIV-1 envelope glycoproteins precedes broad neutralizing response in human infection.

R. Koup, J. Sullivan, G. Mazzara, 1991, Viral immunology.

A phase I trial of a recombinant vaccinia virus expressing prostate-specific antigen in advanced prostate cancer.

P. Kantoff, W. Oh, G. Bubley, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Costimulatory molecules as adjuvants for immunotherapy.

J. Marshall, J. Schlom, H. Sabzevari, 2006, Frontiers in bioscience : a journal and virtual library.

Construction of live vaccines by using genetically engineered poxviruses: biological activity of recombinant vaccinia virus expressing influenza virus hemagglutinin.

S. Davis, E. Paoletti, D. Panicali, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Identification of NY-ESO-1 Peptide Analogues Capable of Improved Stimulation of Tumor-Reactive CTL1

V. Cerundolo, L. Old, E. Stockert, 2000, The Journal of Immunology.

Potential approach to immunotherapy of chronic lymphocytic leukemia (CLL): enhanced immunogenicity of CLL cells via infection with vectors encoding for multiple costimulatory molecules.

J. Schlom, K. Foon, K. Tsang, 2005, Blood.

Studies of cloned simian immunodeficiency virus-specific T lymphocytes. gag-specific cytotoxic T lymphocytes exhibit a restricted epitope specificity.

R. Young, D. Watkins, N. Letvin, 1990, Journal of immunology.

Recombinant virus vaccine-induced SIV-specific CD8+ cytotoxic T lymphocytes.

N. Letvin, M. D. Miller, G. Mazzara, 1991, Science.

Active immunotherapy of cancer with a nonreplicating recombinant fowlpox virus encoding a model tumor-associated antigen.

S. Rosenberg, L. Gritz, V. Bronte, 1995, Journal of immunology.

Tumor-Reactive CTL Analogues Capable of Improved Stimulation Identification of NY-ESO-1 Peptide and Vincenzo

Yao-Tseng Chen, V. Cerundolo, L. Old, 2000 .

Viruses Encoding the Anchor-modified gp 100 Melanoma Antigen Can Generate Antitumor Immune Responses in Patients with Metastatic Melanoma

S. Rosenberg, P. Hwu, J. Yang, 2003 .

Expression of Mycobacterium tuberculosis and Mycobacterium leprae proteins by vaccinia virus

J. Lyons, A. Mahr, D. Panicali, 1990, Infection and immunity.

Delineation of the viral products of recombination in vaccinia virus-infected cells

D. Panicali, D. Spyropoulos, L. Cohen, 1988, Journal of virology.

Heterologous Prime/Boost Immunization of Rhesus Monkeys by Using Diverse Poxvirus Vectors

Jenny G. Parvani, D. Montefiori, S. Santra, 2007, Journal of Virology.

Dysfunction of Simian Immunodeficiency Virus/Simian Human Immunodeficiency Virus-Induced IL-2 Expression by Central Memory CD4+ T Lymphocytes1

J. Mascola, J. Schmitz, S. Santra, 2005, The Journal of Immunology.

Recombinant poxvirus boosting of DNA-primed rhesus monkeys augments peak but not memory T lymphocyte responses.

D. Montefiori, R. Gelman, J. Schmitz, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Granulocyte/macrophage-colony stimulating factor produced by recombinant avian poxviruses enriches the regional lymph nodes with antigen-presenting cells and acts as an immunoadjuvant.

J. Schlom, J. Greiner, G. Mazzara, 2001, Cancer research.

Immunoadjuvant Lymph Nodes with Antigen-presenting Cells and Acts as an by Recombinant Avian Poxviruses Enriches the Regional Granulocyte / Macrophage-Colony Stimulating Factor Produced Updated

J. Schlom, J. Greiner, G. Mazzara, 2000 .

Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas.

J. Marshall, J. Schlom, R. Slack, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I study of a vaccine using recombinant vaccinia virus expressing PSA (rV‐PSA) in patients with metastatic androgen‐independent prostate cancer

S. Steinberg, A. Chen, J. Schlom, 2002, The Prostate.

Formation of lentivirus particles by mammalian cells infected with recombinant fowlpox virus.

L. Gritz, D. Panicali, L. Cohen, 1991, AIDS research and human retroviruses.

Analyses of Recombinant Vaccinia and Fowlpox Vaccine Vectors Expressing Transgenes for Two Human Tumor Antigens and Three Human Costimulatory Molecules

J. Schlom, L. Gritz, J. Gulley, 2005, Clinical Cancer Research.

Immunogenicity of Recombinant Adenovirus Serotype 35 Vaccine in the Presence of Pre-Existing Anti-Ad5 Immunity1

S. Kostense, M. Lifton, N. Letvin, 2004, The Journal of Immunology.

Effect of cordycepin triphosphate on in vitro RNA synthesis by picornavirus polymerase complexes

D. Panicali, C. N. Nair, 1978, Journal of virology.

Effective tumor immunotherapy directed against an oncogene-encoded product using a vaccinia virus vector.

R. Weinberg, D. Panicali, A. Destree, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of allergic encephalomyelitis in marmosets by vaccination with recombinant vaccinia virus encoding for myelin basic protein

N. Letvin, S. Hauser, L. Gritz, 1997, Journal of Neuroimmunology.

Virus burden in long-term survivors of human immunodeficiency virus (HIV) infection is a determinant of anti-HIV CD8+ lymphocyte activity.

R. Detels, A. Kaplan, J. Giorgi, 1995, The Journal of infectious diseases.

HIV-1-specific cytotoxic T lymphocyte responses in the first year of life.

J. Sullivan, K. Luzuriaga, J. Wong, 1995, Journal of immunology.

A Phase 1 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 subtype C-modified vaccinia Ankara virus vaccine candidate in Indian volunteers.

S. Kochhar, J. Excler, P. Fast, 2009, AIDS research and human retroviruses.

Immunization with lentivirus-like particles elicits a potent SIV-specific recall cytotoxic T-lymphocyte response in rhesus monkeys.

N. Letvin, G. Mazzara, D. Panicali, 1993, AIDS research and human retroviruses.

Clinical Protocol A Phase I Trial of Intralesional rV-Tricom Vaccine in the Treatment of Malignant Melanoma

Principal Investigator, H. Kaufman, G. Deraffele, 2001 .

A phase I trial of intra lesional RV-B7.1 vaccine in the treatment of malignant melanoma.

T. Ravikumar, S. Mani, H. Kaufman, 2000, Human gene therapy.

Generation of hybrid genes and proteins by vaccinia virus-mediated recombination: application to human immunodeficiency virus type 1 env

L. Gritz, G. Mazzara, D. Panicali, 1990, Journal of virology.

Construction of live vaccines using genetically engineered poxviruses: biological activity of vaccinia virus recombinants expressing the hepatitis B virus surface antigen and the herpes simplex virus glycoprotein D.

E. Paoletti, D. Panicali, S. Mercer, 1984, Proceedings of the National Academy of Sciences of the United States of America.

A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects.

D. Montefiori, M. McElrath, P. Goepfert, 2011, Vaccine.

Gene gun‐based nucleic acid immunization alone or in combination with recombinant vaccinia vectors suppresses virus burden in rhesus macaques challenged with a heterologous SIV

J. Clements, D. Fuller, R. Montelaro, 1997, Immunology and cell biology.

Recombinant vaccinia-PSA (PROSTVAC) can induce a prostate-specific immune response in androgen-modulated human prostate cancer.

K. Pienta, J. Montie, D. Smith, 1999, Urology.

Clinical protocol. Intra-Lesional rF-B7.1 versus rF-TRICOM vaccine in the treatment of metastatic cancer.

H. Kaufman, C. Hesdorffer, H. Horig, 2003, Human gene therapy.

Analysis of cytotoxic T lymphocyte responses to SIV proteins in SIV-infected macaques using antigen-specific stimulation with recombinant vaccinia and fowl poxviruses.

S. Kent, P. Greenberg, L. Corey, 1994, AIDS research and human retroviruses.

Phase I Study of Immunizationwith Dendritic Cells Modifiedwith Fowlpox Encoding Carcinoembryonic Antigen and CostimulatoryMolecules

J. Schlom, D. Niedzwiecki, H. Lyerly, 2005 .

Strategies for the development of recombinant vaccines for the immunotherapy of breast cancer

J. Schlom, S. Abrams, J. Kantor, 2005, Breast Cancer Research and Treatment.

Transient expression system to measure the efficiency of vaccinia promoter regions.

D. Panicali, C. Huang, B. Shepard, 1987, Plasmid.

Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer.

P. Kantoff, J. Schlom, L. M. Glodé, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Enhanced activation of human T cells via avipox vector-mediated hyperexpression of a triad of costimulatory molecules in human dendritic cells.

J. Schlom, H. Terasawa, K. Tsang, 2001, Cancer research.

Molecules in Human Dendritic Cells Vector-mediated Hyperexpression of a Triad of Costimulatory Enhanced Activation of Human T Cells via Avipox Updated

J. Schlom, H. Terasawa, J. Gulley, 2001 .

Phase I study of immunization with dendritic cells (DC) modified with recombinant fowlpox encoding carcinoembryonic antigen (CEA) and the triad of costimulatory molecules CD54, CD58, and CD80 (rF-CEA(6D)-TRICOM) in patients with advanced malignancies.

M. Morse, H. Lyerly, D. Panicali, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Induction of antigen-specific killer T lymphocyte responses using subunit SIVmac251 gag and env vaccines containing QS-21 saponin adjuvant.

C. Kensil, J. Y. Wu, M. Newman, 1994, AIDS research and human retroviruses.

Antibody-dependent cell-mediated cytotoxicity directed by a human monoclonal antibody reactive with gp120 of HIV-1.

J. Robinson, R. Koup, J. Sullivan, 1991, AIDS.

A recombinant vaccinia virus expressing human prostate‐specific antigen (PSA): Safety and immunogenicity in a non‐human primate

J. Schlom, L. Gritz, J. Kantor, 1995, International journal of cancer.

encoding for multiple costimulatory molecules (CLL): enhanced immunogenicity of CLL cells via infection with vectors Potential approach to immunotherapy of chronic lymphocytic leukemia

J. Schlom, K. Foon, K. Tsang, 2013 .

Vaccinia virus vectors utilizing the beta-galactosidase assay for rapid selection of recombinant viruses and measurement of gene expression.

D. Panicali, C. Huang, A. Grzelecki, 1986, Gene.

Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6).

D. Montefiori, Shiu-Lok Hu, Z. Ambrose, 2003, Virology.

Avipox-based simian immunodeficiency virus (SIV) vaccines elicit a high frequency of SIV-specific CD4+ and CD8+ T-cell responses in vaccinia-experienced SIVmac251-infected macaques.

D. Venzon, J. Tartaglia, G. Franchini, 2004, Vaccine.

Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus.

E. Paoletti, D. Panicali, Enzo Paoleti, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

R. Desrosiers, P. Sehgal, D. Panicali, 1991, Cell.

Two distinct lymphocyte populations mediate simian immunodeficiency virus envelope-specific target cell lysis.

D. Watkins, N. Letvin, L. Gritz, 1990, Journal of immunology.

Polyadenylate sequences of human rhinovirus and poliovirus RNA and cordycepin sensitivity of virus replication

D. Panicali, C. N. Nair, 1976, Journal of virology.

A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer.

S. Steinberg, J. Schlom, E. Jones, 2006, Clinical cancer research : an official journal of the American Association for Cancer Research.

Phase I Study of Immunization with Dendritic Cells Modified with Fowlpox Encoding Carcinoembryonic Antigen and Costimulatory Molecules

J. Schlom, D. Niedzwiecki, H. Lyerly, 2005, Clinical Cancer Research.

High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors

C. Rinaldo, Xiao-li Huang, M. Cottrill, 1995, Journal of virology.

A phase II randomized clinical trial of samarium-153 EDTMP (Sm-153) with or without PSA-TRICOM vaccine in metastatic castration-resistant prostate cancer (mCRPC) after docetaxel.

S. Steinberg, R. DiPaola, J. Schlom, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Therapeutic vaccination against murine lymphoma by intratumoral injection of recombinant fowlpox virus encoding CD40 ligand.

M. Goldstein, Aichun Liu, D. Panicali, 2007, Cancer research.

Vaccine-Elicited Memory Cytotoxic T Lymphocytes Contribute to Mamu-A*01-Associated Control of Simian/Human Immunodeficiency Virus 89.6P Replication in Rhesus Monkeys

J. Mascola, R. Gelman, S. Santra, 2005, Journal of Virology.

Preservation of Functional Virus-Specific Memory CD8+ T Lymphocytes in Vaccinated, Simian Human Immunodeficiency Virus-Infected Rhesus Monkeys1

J. Mascola, J. Schmitz, S. Santra, 2006, Journal of Immunology.

High-titer immune responses elicited by recombinant vaccinia virus priming and particle boosting are ineffective in preventing virulent SIV infection.

R. Desrosiers, M. Simon, P. Sehgal, 1994, AIDS research and human retroviruses.

Detection of major histocompatibility complex class I-restricted, HIV-specific cytotoxic T lymphocytes in the blood of infected hemophiliacs.

R. Koup, D. Brettler, P. Levine, 1989, Blood.

Targeting the local tumor microenvironment with vaccinia virus expressing B7.1 for the treatment of melanoma.

F. Marincola, E. Wang, H. Kaufman, 2005, The Journal of clinical investigation.

Human immunodeficiency virus type 1-specific cytotoxic T lymphocytes (CTL), virus load, and CD4 T cell loss: evidence supporting a protective role for CTL in vivo.

T. Greenough, D. Brettler, M. Somasundaran, 1997, The Journal of infectious diseases.

Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients

D. Jäger, J. Karbach, L. Old, 2006, Proceedings of the National Academy of Sciences.

Antigenic specificity of antibody-dependent cell-mediated cytotoxicity directed against human immunodeficiency virus in antibody-positive sera

R. Koup, P. Levine, J. Sullivan, 1989, Journal of virology.

Early HIV-1 Envelope-specific Cytotoxic T Lymphocyte Responses in Vertically Infected Infants

J. Sullivan, K. Luzuriaga, D. Panicali, 1997, The Journal of experimental medicine.

Safety and immunogenicity of recombinant poxvirus HIV-1 vaccines in young adults on highly active antiretroviral therapy.

T. Greenough, P. Barker, D. Persaud, 2008, Vaccine.

Evaluation of Prime/Boost Regimens Using Recombinant Poxvirus/Tyrosinase Vaccines for the Treatment of Patients with Metastatic Melanoma

S. Steinberg, S. Rosenberg, M. Gonzales, 2006, Clinical Cancer Research.

A phase I trial of intralesional rV-Tricom vaccine in the treatment of malignant melanoma.

H. Kaufman, D. Lee, G. Deraffele, 2001, Human gene therapy.

HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells and cloned effector cells.

B. Walker, A. Trocha, R. Johnson, 1991, Journal of immunology.

A Randomized Phase II Study of Concurrent Docetaxel Plus Vaccine Versus VaccineAlone in Metastatic Androgen-Independent Prostate Cancer

J. Schlom, Clara C. Chen, W. Dahut, 2006 .

Molecular genetics of vaccinia virus: demonstration of marker rescue.

E. Paoletti, D. Panicali, E. Nakano, 1982, Proceedings of the National Academy of Sciences of the United States of America.

ARandomized Phase II Study of Concurrent Docetaxel Plus Vaccine Versus VaccineAlone inMetastatic Androgen-Independent Prostate Cancer

S. Steinberg, J. Schlom, Clara C. Chen, 2006 .

Analysis of vaccinia virus transcriptional complexity in vitro and in vivo: characterization of RNase T1-resistant 5'-terminal oligonucleotides

E. Paoletti, D. Panicali, S. Mercer, 1982, Journal of virology.

Generation and characterization of monoclonal antibodies specific for the human neu oncogene product, p185.

W. Carney, S. McKenzie, D. Panicali, 1989, Oncogene.

Prospect: A randomized double-blind phase 3 efficacy study of PROSTVAC-VF immunotherapy in men with asymptomatic/minimally symptomatic metastatic castration-resistant prostate cancer.

P. Kantoff, J. Schlom, J. Gulley, 2015 .

Polyadenylate Sequences ofHumanRhinovirus and Poliovirus RNA andCordycepin Sensitivity ofVirus Replication

D. Panicali, C. N. Nair, 1976 .

Prior DNA immunization enhances immune response to dominant and subdominant viral epitopes induced by a fowlpox-based SIVmac vaccine in long-term slow-progressor macaques infected with SIVmac251.

D. Venzon, E. Tryniszewska, G. Franchini, 2003, Virology.

Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus. 1982.

E. Paoletti, D. Panicali, 1992, Biotechnology.

Normal immune function and inability to isolate virus in culture in an individual with long-term human immunodeficiency virus type 1 infection.

T. Greenough, F. Kirchhoff, D. Brettler, 1994, AIDS research and human retroviruses.

A phase I study of sequential vaccinations with recombinant Fowlpox-PSA (L155)-TRICOM (rF)alone, or in combination with recombinant vaccinia-PSA (L155)-TRICOM (rV), and the role of GM-CSF, in patients (Pts) with prostate cancer.

J. Schlom, W. Dahut, K. Tsang, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Safety profile of therapeutic pox virus-based vaccines for cancer.

R. DiPaola, J. Marshall, J. Schlom, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations

D. Montefiori, J. Lifson, R. Johnson, 1999, Nature Medicine.

Capped and polyadenylated low-molecular-weight RNA synthesized by vaccinia virus in vitro

E. Paoletti, D. Panicali, B. R. Lipinskas, 1980, Journal of virology.