Victor Nizet

发表

Group B streptococcal beta-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis.

V. Nizet, George Y. Liu, K. Doran, 2003, The Journal of clinical investigation.

Conserved patterns hidden within group A Streptococcus M protein hypervariability are responsible for recognition of human C4b-binding protein

Rommie E. Amaro, Tapan Biswas, Partho Ghosh, 2016, Nature Microbiology.

A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues

Amnon Peled, V. Nizet, A. Peled, 2006, The EMBO journal.

Streptococcal M1 protein constructs a pathological host fibrinogen network

John E. Johnson, Partho Ghosh, Chi-yu Fu, 2011, Nature.

Innate antimicrobial peptide protects the skin from invasive bacterial infection

Takaaki Ohtake, V. Nizet, J. Trowbridge, 2001, Nature.

A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection

V. Nizet, R. Johnson, M. Köckritz-Blickwede, 2012, Journal of Molecular Medicine.

Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus.

Rong Cao, Eric Oldfield, Hong Wang, 2009, Journal of medicinal chemistry.

Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections

Hans Hengartner, Mike Recher, V. Nizet, 2009, Proceedings of the National Academy of Sciences.

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

Toby Lawrence, Michael Karin, V. Nizet, 2005, Nature.

Mechanisms of group A Streptococcus resistance to reactive oxygen species

V. Nizet, Victor Nizet, Anna Henningham, 2015, FEMS microbiology reviews.

Imaging mass spectrometry of intraspecies metabolic exchange revealed the cannibalistic factors of Bacillus subtilis

Pavel A Pevzner, Pieter C Dorrestein, Julio Ng, 2010, Proceedings of the National Academy of Sciences.

IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation.

Toby Lawrence, Michael Karin, V. Nizet, 2005, Nature.

Invasive M1T1 group A Streptococcus undergoes a phase‐shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB

Rita Kansal, Malak Kotb, V. Nizet, 2003, Molecular microbiology.

Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus

Timothy C. Barnett, V. Nizet, J. McArthur, 2014, Clinical Microbiology Reviews.

Chemical Impacts of the Microbiome Across Scales Reveal Novel Conjugated Bile Acids

Rob Knight, Mingxun Wang, Pieter C. Dorrestein, 2019, bioRxiv.

Experimental Selection for Drosophila Survival in Extremely High O2 Environments

Gabriel G. Haddad, V. Nizet, G. Haddad, 2007, PloS one.

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps

Andrés Hidalgo, Georg Schett, Rostyslav Bilyy, 2019, Cell Death and Differentiation.

DNase Expression Allows the Pathogen Group A Streptococcus to Escape Killing in Neutrophil Extracellular Traps

Ramy K. Aziz, Malak Kotb, John T. Buchanan, 2006, Current Biology.

Pharmacological Properties of the Marine Natural Product Marinopyrrole A against Methicillin-Resistant Staphylococcus aureus

William Fenical, Paul R. Jensen, V. Nizet, 2011, Antimicrobial Agents and Chemotherapy.

Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance

Bernhard O Palsson, Yara Seif, Jonathan M Monk, 2018, Nature Communications.

Top-down mass spectrometry on low-resolution instruments: characterization of phosphopantetheinylated carrier domains in polyketide and non-ribosomal biosynthetic pathways.

Pieter C. Dorrestein, Dario Meluzzi, P. Dorrestein, 2008, Bioorganic & medicinal chemistry letters.

DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection

Malak Kotb, Ramy K Aziz, V. Nizet, 2007, Nature Medicine.

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

Katerina Akassoglou, Monica Guma, Jordi Rius, 2008, Nature.

Global chemical effects of the microbiome include new bile-acid conjugations

Julie C. Lumeng, Rob Knight, Mingxun Wang, 2020, Nature.

Antibacterial drug leads targeting isoprenoid biosynthesis

William Sinko, J Andrew McCammon, Steffen Lindert, 2012, Proceedings of the National Academy of Sciences.

Comparative genome-scale modelling of Staphylococcus aureus strains identifies strain-specific metabolic capabilities linked to pathogenicity

Marco Fondi, Emanuele Bosi, Jonathan M Monk, 2016, Proceedings of the National Academy of Sciences.

Antimicrobial peptides and the skin

V. Nizet, R. Gallo, Victor Nizet, 2004, Expert opinion on biological therapy.

Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).

V. Nizet, E. Rankin, R. Johnson, 2007, The Journal of clinical investigation.

Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1α.

Henry Yang, Kaibo Duan, Michael Poidinger, 2015, Immunity.

Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules

Bradley S Moore, Pieter C Dorrestein, David J Gonzalez, 2013, Proceedings of the National Academy of Sciences.

Color me bad: microbial pigments as virulence factors.

V. Nizet, George Y. Liu, George Y Liu, 2009, Trends in microbiology.

Discovery of a widely distributed toxin biosynthetic gene cluster

Pieter C Dorrestein, Douglas A Mitchell, P. Dorrestein, 2008, Proceedings of the National Academy of Sciences.

Nafcillin enhances innate immune-mediated killing of methicillin-resistant Staphylococcus aureus

Michael R. Yeaman, Abhay Dhand, V. Nizet, 2013, Journal of Molecular Medicine.

Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis

Peter G. Schultz, Feng Wang, William R. Jacobs, 2015, Proceedings of the National Academy of Sciences.

Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens

Michael D. Burkart, Manfred Rohde, V. Nizet, 2015, EBioMedicine.

ATP Release Guides Neutrophil Chemotaxis via P2Y2 and A3 Receptors

Linda Yip, Paul A. Insel, Yoshiaki Inoue, 2006, Science.

Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection

Forest Rohwer, Kimberly A. Bishop-Lilly, Katherine E. Cilwa, 2017, Antimicrobial Agents and Chemotherapy.