Vaishali Humnabadkar

发表

Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose 2'-oxidase.

S. Cole, Anirban Ghosh, M. Fellows, 2015, Bioorganic & medicinal chemistry.

Simple and Rapid Method To Determine Antimycobacterial Potency of Compounds by Using Autoluminescent Mycobacterium tuberculosis

N. Dhar, V. Ramachandran, V. Balasubramanian, 2014, Antimicrobial Agents and Chemotherapy.

UDP-N-Acetylmuramic Acid l-Alanine Ligase (MurC) Inhibition in a tolC Mutant Escherichia coli Strain Leads to Cell Death

A. Narayan, V. Ramachandran, Vaishali Humnabadkar, 2014, Antimicrobial Agents and Chemotherapy.

Aminopyrazinamides: novel and specific GyrB inhibitors that kill replicating and nonreplicating Mycobacterium tuberculosis.

J. Tucker, T. Balganesh, V. Sambandamurthy, 2013, ACS chemical biology.

Assays, Surrogates, and Alternative Technologies for a TB Lead Identification Program Targeting DNA Gyrase ATPase

K. Mukherjee, Vaishali Humnabadkar, Aishwarya Sundaram, 2015, Journal of biomolecular screening.

Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy.

Vijay T. Ahuja, D. Ogg, P. Boriack-Sjodin, 2014, Bioorganic & medicinal chemistry letters.

Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase B.

Vijay T. Ahuja, D. Ogg, J. Tucker, 2013, Journal of medicinal chemistry.

4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.

J. Mckinney, L. Chiarelli, N. Dhar, 2014, Journal of medicinal chemistry.

Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity.

A. Narayan, V. Ramachandran, V. Sambandamurthy, 2014, Journal of medicinal chemistry.

Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.

Vijay T. Ahuja, A. Srivastava, A. Narayan, 2013, Journal of medicinal chemistry.

Lead optimization of 1,4-azaindoles as antimycobacterial agents.

Christopher B. Cooper, S. Butler, A. Srivastava, 2014, Journal of medicinal chemistry.

2-Phenylindole and Arylsulphonamide: Novel Scaffolds Bactericidal against Mycobacterium tuberculosis.

G. Balakrishnan, A. Narayan, V. Ramachandran, 2014, ACS medicinal chemistry letters.

Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity

M. Fellows, J. Neres, V. Ramachandran, 2016, ChemMedChem.

Pyrazolopyrimidines establish MurC as a vulnerable target in Pseudomonas aeruginosa and Escherichia coli.

C. Eyermann, B. Paul, V. Sambandamurthy, 2014, ACS chemical biology.

A High-Throughput Screening Assay for Simultaneous Selection of Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-Xylulose-5-Phosphate Synthase (Dxs) or 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (Dxr)

Vaishali Humnabadkar, R. Jha, Sunita M de Sousa, 2011, Journal of biomolecular screening.

1-Deoxy-D-Xylulose-5-Phosphate Synthase (Dxs) or 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (Dxr) Mycobacterium tuberculosis A High-Throughput Screening Assay for Simultaneous Selection of Inhibitors of

Vaishali Humnabadkar, R. Jha, Sunita M. de Sousa, 2013 .

Optimization of Pyrrolamides as Mycobacterial GyrB ATPase Inhibitors: Structure-Activity Relationship and In Vivo Efficacy in a Mouse Model of Tuberculosis

Anirban Ghosh, K. Mukherjee, V. Subbulakshmi, 2013, Antimicrobial Agents and Chemotherapy.

Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.

Anirban Ghosh, K. Mukherjee, S. Hoffner, 2014, Journal of medicinal chemistry.