Disha Awasthy

发表

Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose 2'-oxidase.

S. Cole, Anirban Ghosh, M. Fellows, 2015, Bioorganic & medicinal chemistry.

Optimization of Compound Plate Preparation to Address Precipitation Issue in Mammalian A549 Cytotoxicity Assay

Disha Awasthy, Vijayashree Gauribidanur Raghavendra Achar, S. Barde, 2016, Journal of laboratory automation.

Validation of whole genome sequencing from dried blood spots

B. P. Vani, V. Chandru, L. Subaiya, 2021, BMC medical genomics.

Diarylthiazole: an antimycobacterial scaffold potentially targeting PrrB-PrrA two-component system.

A. Narayan, V. Ramachandran, R. Mclaughlin, 2014, Journal of medicinal chemistry.

Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate

D. Wirth, D. Fidock, Pavithra Viswanath, 2015, Nature Communications.

Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target.

C. Eyermann, G. Balakrishnan, F. Reck, 2015, Tuberculosis.

4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.

J. Mckinney, L. Chiarelli, N. Dhar, 2014, Journal of medicinal chemistry.

Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.

Vijay T. Ahuja, A. Srivastava, A. Narayan, 2013, Journal of medicinal chemistry.

N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds.

D. Fidock, F. Gamo, A. Srivastava, 2014, Journal of medicinal chemistry.

Aminoazabenzimidazoles, a novel class of orally active antimalarial agents.

D. Wirth, F. Gamo, Pavithra Viswanath, 2014, Journal of medicinal chemistry.

Optimization of Pyrrolamides as Mycobacterial GyrB ATPase Inhibitors: Structure-Activity Relationship and In Vivo Efficacy in a Mouse Model of Tuberculosis

Anirban Ghosh, K. Mukherjee, V. Subbulakshmi, 2013, Antimicrobial Agents and Chemotherapy.

Whole cell screen based identification of spiropiperidines with potent antitubercular properties.

Vasanthi Ramachandran, Riccardo Manganelli, S. Cole, 2015, Bioorganic & medicinal chemistry letters.

Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice.

V. Subbulakshmi, S. Bharath, S. Gaonkar, 2009, Microbiology.

Alanine racemase mutants of Mycobacterium tuberculosis require D-alanine for growth and are defective for survival in macrophages and mice.

V. Subbulakshmi, S. Bharath, Disha Awasthy, 2012, Microbiology.

Roles of the two type II NADH dehydrogenases in the survival of Mycobacterium tuberculosis in vitro.

Disha Awasthy, U. Sharma, Anisha Ambady, 2014, Gene.

Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.

Anirban Ghosh, K. Mukherjee, S. Hoffner, 2014, Journal of medicinal chemistry.

Essentiality and functional analysis of type I and type III pantothenate kinases of Mycobacterium tuberculosis.

K. Mukherjee, V. Subbulakshmi, V. Sambandamurthy, 2010, Microbiology.

Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target.

C. Eyermann, G. Balakrishnan, F. Reck, 2015, Tuberculosis.

Revisiting the essentiality of glutamate racemase in Mycobacterium tuberculosis.

Disha Awasthy, U. Sharma, Anisha Ambady, 2015, Gene.