Katherine Tugusheva

Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement.

Paul Zuck, Georgia McGaughey, Amy S. Espeseth, 2009, Bioorganic & medicinal chemistry letters.

Biochemical and cell-based assays for characterization of BACE-1 inhibitors.

Xiao-Ping Shi, Amy S Espeseth, Min Xu, 2005, Analytical biochemistry.

SAR of tertiary carbinamine derived BACE1 inhibitors: role of aspartate ligand amine pKa in enzyme inhibition.

Adam J. Simon, Georgia B. McGaughey, Philippe G. Nantermet, 2010, Bioorganic & medicinal chemistry letters.

Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase.

Paul Zuck, Georgia B McGaughey, M Katharine Holloway, 2008, Journal of medicinal chemistry.