Natalia A Trayanova

发表

From mitochondrial ion channels to arrhythmias in the heart: computational techniques to bridge the spatio-temporal scales

Gernot Plank, Lufang Zhou, Joseph L Greenstein, 2008, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

Mechanistic inquiry into decrease in probability of defibrillation success with increase in complexity of preshock reentrant activity.

Natalia A Trayanova, Matthew G Hillebrenner, James C Eason, 2004, American journal of physiology. Heart and circulatory physiology.

Electromechanical models of the ventricles.

Viatcheslav Gurev, Natalia A Trayanova, Jason Constantino, 2011, American journal of physiology. Heart and circulatory physiology.

Termination of re‐entrant atrial tachycardia via optogenetic stimulation with optimized spatial targeting: insights from computational models

Thomas V. Karathanos, Natalia A Trayanova, Patrick M Boyle, 2018, The Journal of physiology.

Universal atrial coordinates applied to visualisation, registration and construction of patient specific meshes

Marianna Meo, Rémi Dubois, Hubert Cochet, 2018, Medical Image Anal..

Integrative computational models of cardiac arrhythmias -- simulating the structurally realistic heart.

Natalia A Trayanova, Brock M Tice, N. Trayanova, 2009, Drug discovery today. Disease models.

Mathematical approaches to understanding and imaging atrial fibrillation: significance for mechanisms and management.

Natalia A Trayanova, N. Trayanova, 2014, Circulation research.

Models of stretch-activated ventricular arrhythmias.

Viatcheslav Gurev, Natalia A Trayanova, Jason Constantino, 2010, Journal of electrocardiology.

"Beauty is a light in the heart": the transformative potential of optogenetics for clinical applications in cardiovascular medicine.

Thomas V. Karathanos, Natalia A Trayanova, Patrick M Boyle, 2015, Trends in cardiovascular medicine.

Image-based reconstruction of three-dimensional myocardial infarct geometry for patient-specific modeling of cardiac electrophysiology.

Eranga Ukwatta, Martin Rajchl, Natalia A Trayanova, 2015, Medical physics.

New insights into defibrillation of the heart from realistic simulation studies.

Natalia A Trayanova, Lukas J Rantner, N. Trayanova, 2014, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations.

Thomas V. Karathanos, Natalia A Trayanova, Philipp Sasse, 2016, The Journal of clinical investigation.

Computational rabbit models to investigate the initiation, perpetuation, and termination of ventricular arrhythmia.

Natalia A Trayanova, Patrick M Boyle, N. Trayanova, 2016, Progress in biophysics and molecular biology.

Mathematical simulations of ligand-gated and cell-type specific effects on the action potential of human atrium.

Joseph L Greenstein, Natalia A Trayanova, Mary M Maleckar, 2008, Progress in biophysics and molecular biology.

Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling.

Thomas O'Hara, Julia Gorelik, Natalia A Trayanova, 2014, Journal of molecular and cellular cardiology.

Mechanisms Underlying Isovolumic Contraction and Ejection Peaks in Seismocardiogram Morphology.

Viatcheslav Gurev, Bozena Kaminska, Kouhyar Tavakolian, 2012, Journal of medical and biological engineering.

Rate-dependent action potential alternans in human heart failure implicates abnormal intracellular calcium handling.

Natalia A Trayanova, Sanjiv M Narayan, N. Trayanova, 2009, Heart rhythm.

Virtual Electrode‐Induced Positive and Negative Graded Responses:

Natalia A Trayanova, Richard A Gray, James C Eason, 2003, Journal of cardiovascular electrophysiology.

The role of mechanoelectric feedback in vulnerability to electric shock.

Viatcheslav Gurev, Andrew D McCulloch, Natalia A Trayanova, 2008, Progress in biophysics and molecular biology.

The long and the short of long and short duration ventricular fibrillation.

Natalia A Trayanova, N. Trayanova, 2008, Circulation research.

Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones.

Thomas O'Hara, Natalia A Trayanova, Fijoy Vadakkumpadan, 2012, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Arrhythmia risk stratification based on QT interval instability: an intracardiac electrocardiogram study.

Natalia A Trayanova, Ronald D Berger, N. Trayanova, 2013, Heart rhythm.

Unstable QT Interval Dynamics Precedes Ventricular Tachycardia Onset in Patients With Acute Myocardial Infarction: A Novel Approach to Detect Instability in QT Interval Dynamics From Clinical ECG

Natalia A Trayanova, Ronald D Berger, N. Trayanova, 2011, Circulation. Arrhythmia and electrophysiology.

Feasibility of using patient-specific models and the "minimum cut" algorithm to predict optimal ablation targets for left atrial flutter.

Natalia A Trayanova, Hugh Calkins, Jonathan Chrispin, 2016, Heart rhythm.

Modelling methodology of atrial fibrosis affects rotor dynamics and electrograms.

Rémi Dubois, Hubert Cochet, Michel Haïssaguerre, 2016, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Differences Between Left and Right Ventricular Chamber Geometry Affect Cardiac Vulnerability to Electric Shocks

Natalia A Trayanova, Li Li, Igor R Efimov, 2005, Circulation research.

See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?

Natalia A Trayanova, Emilia Entcheva, Patrick M Boyle, 2014, Expert review of cardiovascular therapy.

A computational approach to understanding the cardiac electromechanical activation sequence in the normal and failing heart, with translation to the clinical practice of CRT.

Natalia A Trayanova, Jason Constantino, N. Trayanova, 2012, Progress in biophysics and molecular biology.

Asymmetry in membrane responses to electric shocks: insights from bidomain simulations.

Natalia A Trayanova, Takashi Ashihara, N. Trayanova, 2004, Biophysical journal.

Towards personalized computational modelling of the fibrotic substrate for atrial arrhythmia.

Natalia A Trayanova, Patrick M Boyle, Sohail Zahid, 2016, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Patient-specific modeling of the heart: estimation of ventricular fiber orientations.

Natalia A Trayanova, Hermenegild Arevalo, Fijoy Vadakkumpadan, 2013, Journal of visualized experiments : JoVE.

Tunnel propagation following defibrillation with ICD shocks: hidden postshock activations in the left ventricular wall underlie isoelectric window.

Natalia A Trayanova, Jason Constantino, Takashi Ashihara, 2010, Heart rhythm.

Mechanistic insight into prolonged electromechanical delay in dyssynchronous heart failure: a computational study.

Natalia A Trayanova, Jason Constantino, Albert C Lardo, 2013, American journal of physiology. Heart and circulatory physiology.

Terminating ventricular tachyarrhythmias using far-field low-voltage stimuli: mechanisms and delivery protocols.

Natalia A Trayanova, Lukas J Rantner, Brock M Tice, 2013, Heart rhythm.

Feasibility of image-based simulation to estimate ablation target in human ventricular arrhythmia.

Hiroshi Ashikaga, Natalia A Trayanova, Hugh Calkins, 2013, Heart rhythm.

Methodology for patient-specific modeling of atrial fibrosis as a substrate for atrial fibrillation.

Gernot Plank, Joshua J. E. Blauer, Natalia A Trayanova, 2012, Journal of electrocardiology.

How computer simulations of the human heart can improve anti‐arrhythmia therapy

Natalia A Trayanova, Kelly C. Chang, N. Trayanova, 2016, The Journal of physiology.

A comprehensive multiscale framework for simulating optogenetics in the heart

Natalia A Trayanova, Emilia Entcheva, Patrick M Boyle, 2013, Nature Communications.

Three‐dimensional mechanisms of increased vulnerability to electric shocks in myocardial infarction: Altered virtual electrode polarizations and conduction delay in the peri‐infarct zone

Gernot Plank, Natalia A Trayanova, Igor R Efimov, 2012, The Journal of physiology.

Defibrillation success with high frequency electric fields is related to degree and location of conduction block.

Natalia A Trayanova, Leslie Tung, Kelly C. Chang, 2013, Heart rhythm.

Cell and tissue responses to electric shocks.

Natalia A Trayanova, Takashi Ashihara, N. Trayanova, 2005, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

A feasibility study of arrhythmia risk prediction in patients with myocardial infarction and preserved ejection fraction.

Natalia A Trayanova, Dongdong Deng, Adityo Prakosa, 2016, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

The role of photon scattering in optical signal distortion during arrhythmia and defibrillation.

Natalia A Trayanova, Blanca Rodriguez, Martin J Bishop, 2007, Biophysical journal.

Models of cardiac electromechanics based on individual hearts imaging data

Viatcheslav Gurev, Natalia A Trayanova, Hermenegild Arevalo, 2011, Biomechanics and modeling in mechanobiology.

Sensitivity of reentrant driver localization to electrophysiological parameter variability in image-based computational models of persistent atrial fibrillation sustained by a fibrotic substrate.

Natalia A Trayanova, Dongdong Deng, Farhad Pashakhanloo, 2017, Chaos.

K+ current changes account for the rate dependence of the action potential in the human atrial myocyte.

Joseph L Greenstein, Natalia A Trayanova, Mary M Maleckar, 2009, American journal of physiology. Heart and circulatory physiology.

The Role of Fibroblasts in Complex Fractionated Electrograms During Persistent/Permanent Atrial Fibrillation: Implications for Electrogram-Based Catheter Ablation

Ryo Haraguchi, Kazuo Nakazawa, Natalia A Trayanova, 2012, Circulation research.

Characterization of the relationship between preshock state and virtual electrode polarization-induced propagated graded responses resulting in arrhythmia induction.

Natalia A Trayanova, Richard A Gray, N. Trayanova, 2006, Heart rhythm.

Personalized Imaging and Modeling Strategies for Arrhythmia Prevention and Therapy.

Natalia A Trayanova, Patrick M Boyle, N. Trayanova, 2018, Current opinion in biomedical engineering.

Mechanisms of Human Atrial Fibrillation Initiation: Clinical and Computational Studies of Repolarization Restitution and Activation Latency

Natalia A Trayanova, Sanjiv M Narayan, Gordon Ho, 2012, Circulation. Arrhythmia and electrophysiology.

Placement of implantable cardioverter‐defibrillators in paediatric and congenital heart defect patients: a pipeline for model generation and simulation prediction of optimal configurations

Natalia A Trayanova, Fijoy Vadakkumpadan, Lukas J Rantner, 2013, The Journal of physiology.

Early somatic mosaicism is a rare cause of long-QT syndrome

Euan A Ashley, Thomas O'Hara, Charles Gawad, 2016, Proceedings of the National Academy of Sciences.

Mechanistic inquiry into the role of tissue remodeling in fibrotic lesions in human atrial fibrillation.

Gernot Plank, Joshua J. E. Blauer, Natalia A Trayanova, 2013, Biophysical journal.

Photon scattering effects in optical mapping of propagation and arrhythmogenesis in the heart.

Natalia A Trayanova, Blanca Rodriguez, Martin J Bishop, 2007, Journal of electrocardiology.

Termination of Reentry by a Long‐Lasting AC Shock in a Slice of Canine Heart: A Computational Study

Natalia A Trayanova, James C Eason, N. Trayanova, 2002, Journal of cardiovascular electrophysiology.

Action potential morphology heterogeneity in the atrium and its effect on atrial reentry: a two-dimensional and quasi-three-dimensional study

Natalia A Trayanova, N. Trayanova, Samuel R Kuo, 2006, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.