Guang-Fu Yang

发表

AIMMS suite: a web server dedicated for prediction of drug resistance on protein mutation

Feng-Xu Wu, Fan Wang, Jing-Fang Yang, 2018, Briefings Bioinform..

Bioinformatics toolbox for exploring protein phosphorylation network

Guang-Fu Yang, Ge-Fei Hao, Xing-Xing Shi, 2020, Briefings Bioinform..

PADFrag: A Database Built for the Exploration of Bioactive Fragment Space for Drug Discovery

Jing-Fang Yang, Wen Jiang, Ge-Fei Hao, 2018, J. Chem. Inf. Model..

ACID: a free tool for drug repurposing using consensus inverse docking strategy

Feng-Xu Wu, Chen-Yang Jia, Guang-Fu Yang, 2019, Journal of Cheminformatics.

1-(2-Methylpropyl)-1 H -imidazo[4,5- c ]quinolin-4-amine

Guang-Fu Yang, Jing Yong Cheng, Zu-Ming Liu, 2005 .

InsectiPAD: A Web Tool Dedicated to Exploring Physicochemical Properties and Evaluating Insecticide-Likeness of Small Molecules

Chen-Yang Jia, Ge-Fei Hao, Guang-Fu Yang, 2019, J. Chem. Inf. Model..

Cloud 3D-QSAR: a web tool for the development of quantitative structure-activity relationship models in drug discovery

Chen-Yang Jia, Guang-Fu Yang, Ge-Fei Hao, 2020, Briefings Bioinform..

LARMD: integration of bioinformatic resources to profile ligand-driven protein dynamics with a case on the activation of estrogen receptor

Jing-Fang Yang, Guang-Fu Yang, Ge-Fei Hao, 2019, Briefings Bioinform..

FungiPAD: A Free Web Tool for Compound Property Evaluation and Fungicide-Likeness Analysis.

Meng-Yao Wang, Ge-Fei Hao, Guang-Fu Yang, 2019, Journal of agricultural and food chemistry.

Development of quantitative structure-activity relationships and its application in rational drug design.

Guang-Fu Yang, Xiaoqin Huang, Guangfu Yang, 2006, Current pharmaceutical design.

A drug-likeness toolbox facilitates ADMET study in drug discovery.

Chen-Yang Jia, Guang-Fu Yang, Ge-Fei Hao, 2019, Drug discovery today.

Graph attention convolutional neural network model for chemical poisoning of honey bees' prediction.

Chen-Yang Jia, Guang-Fu Yang, Ge-Fei Hao, 2020, Science bulletin.

Crystal Structure of 4-Hydroxyphenylpyruvate Dioxygenase in Complex with Substrate Reveals a New Starting Point for Herbicide Discovery

Feng-Xu Wu, Guang-Fu Yang, Chang-Guo Zhan, 2019, Research.

Computational mutation scanning and drug resistance mechanisms of HIV-1 protease inhibitors.

Ge-Fei Hao, Guang-Fu Yang, Chang-Guo Zhan, 2010, The journal of physical chemistry. B.

Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex.

Ge-Fei Hao, Guang-Fu Yang, Xiao-Lei Zhu, 2012, Journal of the American Chemical Society.

QSAR and 3D-QSAR analysis of structurally diverse ALS inhibitors: sulfonylureas and triazolopyrimidine-2-sulfonamides

Guang-Fu Yang, Huazheng Yang, Huayin Liu, 1999 .

Design, synthesis, and bioevaluation of benzamides: novel acetylcholinesterase inhibitors with multi-functions on butylcholinesterase, Aβ aggregation, and β-secretase.

Guang-Fu Yang, Xiao-Lei Zhu, Qi Sun, 2012, Bioorganic & medicinal chemistry.

Structure-based methods for predicting target mutation-induced drug resistance and rational drug design to overcome the problem.

Ge-Fei Hao, Guang-Fu Yang, Chang-Guo Zhan, 2012, Drug discovery today.

Characterization of a catalytic ligand bridging metal ions in phosphodiesterases 4 and 5 by molecular dynamics simulations and hybrid quantum mechanical/molecular mechanical calculations.

Guang-Fu Yang, Chang-Guo Zhan, C. Zhan, 2006, Biophysical journal.

Design and synthesis of N-2,6-difluorophenyl-5-methoxyl-1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamide as acetohydroxyacid synthase inhibitor.

Guang-Fu Yang, Qiong Chen, Feng-Qin Ji, 2009, Bioorganic & medicinal chemistry.

Binding model construction of antifungal 2-aryl-4-chromanones using CoMFA, CoMSIA, and QSAR analyses.

Guang-Fu Yang, Chang-Guo Zhan, Jian Wan, 2005, Journal of agricultural and food chemistry.

Computational Design and Discovery of Conformationally Flexible Inhibitors of Acetohydroxyacid Synthase to Overcome Drug Resistance Associated with the W586L Mutation

Guang-Fu Yang, Chang-Guo Zhan, Qiong Chen, 2008, ChemMedChem.

Multiple Simulated Annealing-Molecular Dynamics (MSA-MD) for Conformational Space Search of Peptide and Miniprotein

Ge-Fei Hao, Guang-Fu Yang, Sheng-Gang Yang, 2015, Scientific Reports.

Syntheses and herbicidal activity of new triazolopyrimidine-2-sulfonamides as acetohydroxyacid synthase inhibitor.

Guang-Fu Yang, Xiao-Lei Zhu, Qiong Chen, 2010, Bioorganic & medicinal chemistry.

Rational Design of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitor as Fungicide by Computational Substitution Optimization

Ge-Fei Hao, Guang-Fu Yang, Wei Huang, 2015, Scientific Reports.

Structure-based drug design: strategies and challenges.

Guang-Fu Yang, Guangfu Yang, 2014, Current pharmaceutical design.

Syntheses and herbicidal activities of novel triazolinone derivatives.

Guang-Fu Yang, Qiong Chen, Li-Li Jiang, 2008, Journal of agricultural and food chemistry.

Detection of Intracellular Selenol-Containing Molecules Using a Fluorescent Probe with Near-Zero Background Signal.

Guang-Fu Yang, Qi Sun, Wenchao Yang, 2016, Analytical chemistry.

Design and syntheses of novel phthalazin-1(2H)-one derivatives as acetohydroxyacid synthase inhibitors.

Guang-Fu Yang, Yan-Zhen He, Yuan-Xiang Li, 2006, Journal of agricultural and food chemistry.

Understanding the mechanism of drug resistance due to a codon deletion in protoporphyrinogen oxidase through computational modeling.

Ge-Fei Hao, Guang-Fu Yang, Li Zhang, 2009, The journal of physical chemistry. B.