Toshikazu Nagao

Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas

Katsuhiko Itoh, Jun Fujita, S. Arii, 2000, Nature Medicine.

The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53.

Tomoko Masuda, Katsuhiko Itoh, Jun Fujita, 2005, Cancer cell.