David H Schaffert

发表

Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins.

Thomas Tørring, Niels V Voigt, Kurt V Gothelf, 2014, Nature chemistry.

New sequence-defined polyaminoamides with tailored endosomolytic properties for plasmid DNA delivery.

D. Schaffert, E. Wagner, Christina Troiber, 2012, Bioconjugate chemistry.

Precise oligoethylenimine-based carriers for nucleic acid delivery

D. Schaffert, David H Schaffert, 2010 .

pH-responsive release of acetal-linked melittin from SBA-15 mesoporous silica.

T. Bein, E. Wagner, David H Schaffert, 2011, Angewandte Chemie.

Intracellular Delivery of a Planar DNA Origami Structure by the Transferrin-Receptor Internalization Pathway.

J. Kjems, K. Gothelf, A. Okholm, 2016, Small.

Click chemistry for high-density biofunctionalization of mesoporous silica.

T. Bein, D. Schaffert, E. Wagner, 2008, Journal of the American Chemical Society.

Gene therapy progress and prospects: synthetic polymer-based systems

D. Schaffert, E. Wagner, David H Schaffert, 2008, Gene Therapy.

Structure-activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides.

D. Schaffert, P. Hadwiger, H. Vornlocher, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Development of a lyophilized plasmid/LPEI polyplex formulation with long-term stability--A step closer from promising technology to application.

D. Schaffert, M. Ogris, E. Wagner, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Construction of a 4 zeptoliters switchable 3D DNA box origami.

Mette D. E. Jepsen, Reza M Zadegan, J. Kjems, 2012, ACS nano.

Towards Defined DNA and RNA Delivery Vehicles Using Nucleic Acid Nanotechnology

Anders H. Okholm, David H. Schaffert, Jørgen Kjems, 2014 .

Quantification of cellular uptake of DNA nanostructures by qPCR.

J. Kjems, A. Okholm, Mathias Vinther, 2014, Methods.

Enzymatic ligation of large biomolecules to DNA.

J. Kjems, K. Gothelf, A. Okholm, 2013, ACS nano.

Epidermal Growth Factor Receptor-targeted 131I-therapy of Liver Cancer Following Systemic Delivery of the Sodium Iodide Symporter Gene.

R. Senekowitsch-Schmidtke, D. Schaffert, M. Ogris, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Epidermal Growth Factor Receptor-targeted 131I-therapy of Liver Cancer Following Systemic Delivery of the Sodium Iodide Symporter Gene.

R. Senekowitsch-Schmidtke, D. Schaffert, M. Ogris, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery.

E. Giralt, E. Wagner, Ulrich Lächelt, 2012, Organic & biomolecular chemistry.

Dual-targeted polyplexes: one step towards a synthetic virus for cancer gene therapy.

Yu Nie, Ernst Wagner, Manfred Ogris, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Poly(I:C)-Mediated Tumor Growth Suppression in EGF-Receptor Overexpressing Tumors Using EGF-Polyethylene Glycol-Linear Polyethylenimine as Carrier

D. Schaffert, A. Levitzki, M. Ogris, 2011, Pharmaceutical Research.

Synthesis of Polyethylenimine-Based Nanocarriers for Systemic Tumor Targeting of Nucleic Acids.

D. Schaffert, M. Ogris, E. Wagner, 2019, Methods in molecular biology.

Synthesis of polyethylenimine-based nanocarriers for systemic tumor targeting of nucleic acids.

D. Schaffert, M. Ogris, E. Wagner, 2013, Methods in molecular biology.

An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications

D. Schaffert, J. Wengel, K. Howard, 2017, Molecular therapy. Nucleic acids.

Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins.

J. Enghild, J. Kjems, K. Gothelf, 2014, Nature chemistry.

Disconnecting the yin and yang relation of epidermal growth factor receptor (EGFR)-mediated delivery: a fully synthetic, EGFR-targeted gene transfer system avoiding receptor activation.

D. Schaffert, R. Kraaij, M. Ogris, 2011, Human gene therapy.

Solid-phase-assisted synthesis of targeting peptide – PEG – oligo ( ethane amino ) amides for receptor-mediated gene delivery †

E. Giralt, D. Schaffert, H. Kessler, 2012 .

Nucleic acid carrier systems based on polyethylenimine conjugates for the treatment of metastatic tumors.

M. Ogris, David H Schaffert, 2013, Current medicinal chemistry.

The establishment of an up-scaled micro-mixer method allows the standardized and reproducible preparation of well-defined plasmid/LPEI polyplexes.

D. Schaffert, M. Ogris, E. Wagner, 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Solid-phase synthesis of sequence-defined T-, i-, and U-shape polymers for pDNA and siRNA delivery.

D. Schaffert, P. Hadwiger, E. Wagner, 2011, Angewandte Chemie.

Novel Fmoc-polyamino acids for solid-phase synthesis of defined polyamidoamines.

D. Schaffert, E. Wagner, N. Badgujar, 2011, Organic letters.