Christian Grütter

High-throughput screening to identify inhibitors which stabilize inactive kinase conformations in p38alpha.

Daniel Rauh, Christian Ottmann, C. Ottmann, 2009, Journal of the American Chemical Society.

Dibenzosuberones as p38 mitogen-activated protein kinase inhibitors with low ATP competitiveness and outstanding whole blood activity.

Daniel Rauh, Kirsten Storch, Frank M Boeckler, 2013, Journal of medicinal chemistry.

A new screening assay for allosteric inhibitors of cSrc.

Daniel Rauh, C. Grütter, D. Rauh, 2009, Nature chemical biology.

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.

Wolfgang Albrecht, Daniel Rauh, Oliver Werz, 2012, Nature chemical biology.

Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach.

Jochen Heil, Franziska Hoffgaard, Julian Engel, 2015, Journal of medicinal chemistry.

ALK Mutations Conferring Differential Resistance to Structurally Diverse ALK Inhibitors

William Pao, Michael Hölzel, Martin Peifer, 2011, Clinical Cancer Research.

Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors.

Daniel Rauh, Jeffrey R. Simard, C. Grütter, 2009, Journal of the American Chemical Society.

Natural-product-derived fragments for fragment-based ligand discovery

Stefan Wetzel, Herbert Waldmann, Daniel Rauh, 2012, Nature Chemistry.

Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components.

Jeremy Luban, Caterina Strambio-De-Castillia, L. Mazzucchelli, 2009, The Journal of clinical investigation.