Sunmi Seok

发表

Transcriptional regulation of autophagy by an FXR/CREB axis

G. Yoon, Yang Li, Wenxuan Zhong, 2014, Nature.

Fructose-1,6-bisphosphate ameliorates lipopolysaccharide-induced dysfunction of blood–brain barrier

E. Baik, Soo Hwan Lee, Sunmi Seok, 2013, Archives of pharmacal research.

MicroRNA 34a Inhibits Beige and Brown Fat Formation in Obesity in Part by Suppressing Adipocyte Fibroblast Growth Factor 21 Signaling and SIRT1 Function

J. Kemper, H. Xu, Sung-E. Choi, 2014, Molecular and Cellular Biology.

Feeding activates FGF15‐SHP‐TFEB‐mediated lipophagy in the gut

J. Kemper, Yang Zhang, Jian Ma, 2022, The EMBO journal.

Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2

Jian Ma, J. Kemper, Yang Zhang, 2015, Genome Biology.

Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes.

T. Willson, Linda Yang, W. Zuercher, 2011, Molecular endocrinology.

COX-2 is associated with cadmium-induced ICAM-1 expression in cerebrovascular endothelial cells.

Yi-Sook Jung, E. Baik, Soo Hwan Lee, 2006, Toxicology letters.

Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption.

J. Kemper, H. Xu, B. Kemper, 2019, Gastroenterology.

FXR Primes the Liver for Intestinal FGF15 Signaling by Transient Induction of β-Klotho.

Dong-Hyun Kim, J. Kemper, H. Xu, 2016, Molecular endocrinology.

Defective FXR-SHP Regulation in Obesity Aberrantly Increases miR-802 Expression, Promoting Insulin Resistance and Fatty Liver

J. Kemper, B. Kemper, Young-Chae Kim, 2020, Diabetes.

Fructose-1,6-bisphosphate suppresses lipopolysaccharide-induced expression of ICAM-1 through modulation of toll-like receptor-4 signaling in brain endothelial cells.

E. Baik, Soo Hwan Lee, Sunmi Seok, 2015, International immunopharmacology.

Obesity-induced miR-802 directly targets AMPK and promotes nonalcoholic steatohepatitis in mice

J. Kemper, B. Kemper, Sunmi Seok, 2022, Molecular metabolism.

Cadmium-induced E-cadherin Expression in Cerebrovascular Endothelial Cells

Yi-Sook Jung, E. Baik, Soo Hwan Lee, 1986 .

Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A

J. Kemper, Yang Zhang, Jian Ma, 2020, Nature Communications.

Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase

J. Kemper, Yang Zhang, Jian Ma, 2020, Nature Communications.

AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle

J. Kemper, Yang Zhang, Jian Ma, 2018, Nature Communications.

Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2

J. Kemper, Yang Zhang, Jian Ma, 2015, Genome Biology.

Elevated microRNA‐34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT

Xiaoling Li, Dong-Hyun Kim, J. Kemper, 2013, Aging cell.

Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho

Dong-Hyun Kim, J. Kemper, H. Xu, 2012, Proceedings of the National Academy of Sciences.

AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle

J. Kemper, Yang Zhang, Jian Ma, 2018, Nature Communications.

Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase

J. Kemper, Yang Zhang, Jian Ma, 2020, Nature Communications.

Fasting‐induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid &bgr;‐oxidation

Zhen Xiao, J. Kemper, Yang Zhang, 2018, The Journal of clinical investigation.

Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3

Xiaoling Li, J. Kemper, B. Kemper, 2017, The Journal of Biological Chemistry.

Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice

Zachary Smith, J. Kemper, P. Yu, 2012, Hepatology.

MicroRNA‐210 Promotes Bile Acid–Induced Cholestatic Liver Injury by Targeting Mixed‐Lineage Leukemia‐4 Methyltransferase in Mice

J. Kemper, Yang Zhang, Jian Ma, 2020, Hepatology.

Obesity-Linked Phosphorylation of SIRT1 by Casein Kinase 2 Inhibits Its Nuclear Localization and Promotes Fatty Liver

Xiaoling Li, Zhen Xiao, J. Kemper, 2017, Molecular and Cellular Biology.

Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease

J. Kemper, M. Qi, B. Kemper, 2023, The Journal of biological chemistry.

Bile Acid Signal-induced Phosphorylation of Small Heterodimer Partner by Protein Kinase Cζ Is Critical for Epigenomic Regulation of Liver Metabolic Genes*

T. Veenstra, Zhen Xiao, J. Kemper, 2013, The Journal of Biological Chemistry.

Farnesoid X receptor–induced lysine‐specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicity

J. Kemper, B. Kemper, S. Byun, 2015, Hepatology.

Membrane phospholipid remodeling modulates nonalcoholic steatohepatitis progression by regulating mitochondrial homeostasis

J. Kemper, D. Ford, Kai Zhang, 2023, Hepatology.