C. Quan

发表

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.

R. Mrsny, J. Turner, Y. Zolotarevsky, 2002, Gastroenterology.

Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

Jinfeng Liu, Saritha Kusam, Jeffrey Tom, 2015, Nature.

X-ray structure of human relaxin at 1·5Å

A. Kossiakoff, C. Eigenbrot, M. Randal, 1991 .

X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants.

C. Eigenbrot, A. Kossiakoff, C. Eigenbrot, 1991, Journal of molecular biology.

Identification of a Novel Polyproline Recognition Site in the Cytoskeletal Associated Protein, Proline Serine Threonine Phosphatase Interacting Protein*

D. Dowbenko, S. Spencer, L. Lasky, 1998, The Journal of Biological Chemistry.

Agonist selectivity for three species of natriuretic peptide receptor-A.

C. Quan, J. Burnier, D. Lowe, 1995, Molecular pharmacology.

Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.

N. Skelton, K. Deshayes, A. Cochran, 2001, Biochemistry.

Synthesis and structure-activity relationship of N-acyl-Gly-, N-acyl-Sar- and N-blocked-boroPro inhibitors of FAP, DPP4, and POP.

D. Sutherlin, C. Wiesmann, M. Mayeda, 2007, Bioorganic & medicinal chemistry letters.

Selective Inhibition of Fibroblast Activation Protein Protease Based on Dipeptide Substrate Specificity*

D. Sutherlin, W. Fairbrother, J. M. Elliott, 2006, Journal of Biological Chemistry.

Supplemental Information Structural and Functional Analysis of HtrA 1 and Its Subdomains

Ganesan, W. Sandoval, M. Ultsch, 2012 .

Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin.

T. Bui, A. Drake, R. Mrsny, 2005, Molecular biology of the cell.

How much insulin-like growth factor I (IGF-I) circulates? Impact of standardization on IGF-I assay accuracy.

V. Quarmby, C. Quan, E. Canova‐Davis, 1998, The Journal of clinical endocrinology and metabolism.

Selection and characterization of a new class of peptide exosite inhibitors of coagulation factor VIIa.

M. Dennis, R. Lazarus, C. Quan, 2001, Biochemistry.

Structure of a CXC chemokine-receptor fragment in complex with interleukin-8.

N. Skelton, D. Reilly, H. Lowman, 1999, Structure.

Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

Zhaoyang Wen, Brigitte Maurer, Vickie Tsui, 2012, Journal of medicinal chemistry.

From Peptide to Non-Peptide. 1. The Elucidation of a Bioactive Conformation of the Arginine-Glycine-Aspartic Acid Recognition Sequence

Robert S. McDowell, Eugene D. Thorsett, N. Skelton, 1994 .

The Coiled-coil Domain of Occludin Can Act to Organize Structural and Functional Elements of the Epithelial Tight Junction*

M. Cromwell, R. Mrsny, A. Nusrat, 2000, The Journal of Biological Chemistry.

Structural and functional analysis of HtrA1 and its subdomains.

M. van Lookeren Campagne, W. Sandoval, M. Ultsch, 2012, Structure.

Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.

Karen Stanger, R. Hannoush, Y. Franke, 2012, Nature chemical biology.

Stabilizing the pro-apoptotic BimBH3 helix (BimSAHB) does not necessarily enhance affinity or biological activity.

Brian J. Smith, D. Huang, W. Fairbrother, 2013, ACS chemical biology.

Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation

Rekha S. Iyer, R. S. Iyer, M. Starovasnik, 2012, Proceedings of the National Academy of Sciences.

Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

J. DeVoss, D. Seshasayee, W. Sandoval, 2016, Nature.

Multiple novel classes of APRIL-specific receptor-blocking peptides isolated by phage display.

R. Kelley, S. Hymowitz, H. Wallweber, 2010, Journal of molecular biology.

Noncompetitive inhibition of hepatocyte growth factor-dependent Met signaling by a phage-derived peptide.

E. Tam, Steven T. Runyon, N. Skelton, 2009, Journal of molecular biology.

Calcium-independent inhibition of PCSK9 by affinity-improved variants of the LDL receptor EGF(A) domain.

A. Peterson, N. Skelton, Yingnan Zhang, 2012, Journal of molecular biology.

Analysis of PDZ Domain-Ligand Interactions Using Carboxyl-terminal Phage Display*

M. Teresa Pisabarro, Sachdev S. Sidhu, Ying Li, 2000, The Journal of Biological Chemistry.

Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site.

A G Cochran, B. Cunningham, H. Christinger, 1998, Biochemistry.

A key claudin extracellular loop domain is critical for epithelial barrier integrity.

R. Mrsny, A. Buret, A. Nusrat, 2008, The American journal of pathology.

An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides.

C. Eigenbrot, R. Lazarus, C. Quan, 2014, Nature chemical biology.

Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor

Wei Li, Jeffrey Tom, Nicholas J Skelton, 2013, The Journal of Biological Chemistry.

Allosteric Peptide Activators of Pro-Hepatocyte Growth Factor Stimulate Met Signaling

D. Kirchhofer, R. Lazarus, Judy C. Young, 2010, The Journal of Biological Chemistry.

Potent α4β1 Peptide Antagonists as Potential Anti-Inflammatory Agents

Dean R. Artis, W. Fairbrother, Susan Jones, 1997 .

Potent alpha 4 beta 1 peptide antagonists as potential anti-inflammatory agents.

K. Chan, W. Fairbrother, D. R. Artis, 1997, Journal of medicinal chemistry.

Ala657 and conserved active site residues promote fibroblast activation protein endopeptidase activity via distinct mechanisms of transition state stabilization.

C. Wiesmann, M. Mayeda, C. Quan, 2007, Biochemistry.

Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly2‐Pro1‐cleaving specificity

W. Fairbrother, C. Wiesmann, Victoria C. Pham, 2006, FEBS letters.

Determination of the solution structure of the peptide hormone guanylin: observation of a novel form of topological stereoisomerism.

D. Goeddel, K. Garcia, N. Skelton, 1994, Biochemistry.

Characterization of the recombinant human receptor for Escherichia coli heat-stable enterotoxin.

D. Goeddel, F. D. de Sauvage, R. Horuk, 1992, The Journal of biological chemistry.

On the edge of validation--cancer protease fibroblast activation protein.

D. Sutherlin, C. Wiesmann, C. Quan, 2008, Mini-Reviews in Medical Chemistry.

Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.

Karen Stanger, R. Hannoush, Y. Franke, 2012, Nature chemical biology.