J. Tom

发表

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.

R. Mrsny, J. Turner, Y. Zolotarevsky, 2002, Gastroenterology.

Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

Jinfeng Liu, Saritha Kusam, Jeffrey Tom, 2015, Nature.

Heterobifunctional molecules induce dephosphorylation of kinases - a proof of concept study.

Kui Lin, W. Fairbrother, Jie Lin, 2019, Journal of medicinal chemistry.

A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands.

Melinda M. Mulvihill, D. Stoffler, M. Holliday, 2022, Biochemistry.

Supplemental Information Structural and Functional Analysis of HtrA 1 and Its Subdomains

Ganesan, W. Sandoval, M. Ultsch, 2012 .

Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin.

T. Bui, A. Drake, R. Mrsny, 2005, Molecular biology of the cell.

Heterobifunctional Molecules Induce Dephosphorylation of Kinases - a Proof of Concept Study

Kui Lin, W. Fairbrother, Jie Lin, 2019 .

Trifluoroacetyl Lysine as a Bromodomain Binding Mimic of Lysine Acetylation.

G. Miller, A. Cochran, E. M. Flynn, 2022, ACS chemical biology.

Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling.

Christian N. Cunningham, P. Beroza, Rohit Reja, 2020, Cell reports.

Receptor-specific ligands distinguish natriuretic peptide receptors-A and -C in primate tissues

D. Oare, J. Tom, D. Lowe, 2004, Molecular and Cellular Biochemistry.

Novel analog of atrial natriuretic peptide selective for receptor-A produces increased diuresis and natriuresis in rats.

B. Cunningham, R. Yang, D. Oare, 1996, The Journal of clinical investigation.

Mutations in B‐type natriuretic peptide mediating receptor‐A selectivity

J. Tom, D. Lowe, J. Schoenfeld, 1997, FEBS letters.

Designing subtilisin BPN' to cleave substrates containing dibasic residues.

M. Ballinger, J. Tom, J. Wells, 1995, Biochemistry.

Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

Zhaoyang Wen, Brigitte Maurer, Vickie Tsui, 2012, Journal of medicinal chemistry.

Development of orthogonally protected hypusine for solid-phase peptide synthesis.

K. Deshayes, Victoria C. Pham, Aimin Song, 2015, The Journal of organic chemistry.

Evaluating Translational Efficiency of Noncanonical Amino Acids to Inform the Design of Druglike Peptide Libraries

Manali Sawant, Alix I. Chan, Aimin Song, 2023, ACS chemical biology.

Peptide-Cyclizations on solid support: A fast and efficient route to small cyclopeptides

J. Tom, J. Burnier, L. Richter, 1994 .

A novel method to produce synthetic murine CXCL10 for efficient screening of functional variants.

B. Vollmar, J. Payandeh, M. Albert, 2021, Bioorganic chemistry.

A designed peptide ligase for total synthesis of ribonuclease A with unnatural catalytic residues.

J. Tom, J. Burnier, M. Stanley, 1994, Science.

The Coiled-coil Domain of Occludin Can Act to Organize Structural and Functional Elements of the Epithelial Tight Junction*

M. Cromwell, R. Mrsny, A. Nusrat, 2000, The Journal of Biological Chemistry.

Structural and functional analysis of HtrA1 and its subdomains.

M. van Lookeren Campagne, W. Sandoval, M. Ultsch, 2012, Structure.

Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.

Karen Stanger, R. Hannoush, Y. Franke, 2012, Nature chemical biology.

Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor.

B. Pan, W. Fairbrother, A. Cochran, 2002, Journal of molecular biology.

Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

J. DeVoss, D. Seshasayee, W. Sandoval, 2016, Nature.

Calcium-independent inhibition of PCSK9 by affinity-improved variants of the LDL receptor EGF(A) domain.

A. Peterson, N. Skelton, Yingnan Zhang, 2012, Journal of molecular biology.

Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site.

A G Cochran, B. Cunningham, H. Christinger, 1998, Biochemistry.

Engineering subtilisin and its substrates for efficient ligation of peptide bonds in aqueous solution.

A. Kossiakoff, L. Abrahmsén, J. Tom, 1991, Biochemistry.

Minimization of a Polypeptide Hormone

B. Cunningham, W. Fairbrother, D. Oare, 1995, Science.

An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides.

C. Eigenbrot, R. Lazarus, C. Quan, 2014, Nature chemical biology.

Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor

Wei Li, Jeffrey Tom, Nicholas J Skelton, 2013, The Journal of Biological Chemistry.

Incorporating NOE-Derived Distances in Conformer Generation of Cyclic Peptides with Distance Geometry

Benjamin D. Sellers, Anastasia C. Murthy, N. Popovych, 2022, J. Chem. Inf. Model..

Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.

Karen Stanger, R. Hannoush, Y. Franke, 2012, Nature chemical biology.