G. Hollingworth

发表

Preparation of a highly functionalized allylsilane for use in three-bond cascade reactions

G. Hollingworth, Thomas V. Lee, J. Sweeney, 1992 .

3.03 – Aldehydes: Aryl and Heteroaryl Aldehydes

G. Hollingworth, 1995 .

Samarium diiodide mediated 6-exo cyclisations of methylenecyclopropyl ketones

M. Hursthouse, P. Horton, G. Hollingworth, 2004 .

Developments and Advances in Gastrointestinal Prokinetic Agents

G. Hollingworth, J. McKenna, J. Dale, 2011 .

Structure-activity relationship studies on divalent naphthalene diimide G quadruplex ligands with anticancer and antiparasitic activity.

Steven T. G. Street, G. Hollingworth, M. Galán, 2022, Bioorganic & medicinal chemistry.

Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergy.

E. Hirsch, M. Wymann, R. Marone, 2013, The Journal of allergy and clinical immunology.

Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties.

R. Wolf, R. Wilcken, F. Zécri, 2016, Bioorganic & medicinal chemistry letters.

Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors.

G. Rummel, R. Wolf, F. Zécri, 2017, ACS medicinal chemistry letters.

2-Aryl indole NK1 receptor antagonists: optimisation of indole substitution.

K. Tsao, C. Swain, G. Hollingworth, 2001, Bioorganic & medicinal chemistry letters.

2-Aryl indole NK1 receptor antagonists: optimisation of the 2-aryl ring and the indole nitrogen substituent.

K. Tsao, C. Swain, G. Hollingworth, 2001, Bioorganic & medicinal chemistry letters.

Preparation and palladium-catalysed cross-coupling reactions of 3- and 4-tributylstannylfuran-2(5H)-ones

G. Hollingworth, J. Sweeney, G. Perkins, 1996 .

Preparation and reactions of 3- and 4-tributylstannyl-2-(5H)-furanones: Preparation of aryl furanones

G. Hollingworth, J. Sweeney, 1992 .

PREPARATION OF A TRIFUNCTIONAL ALLYLSILANE FOR USE IN THREE-BOND CASCADE REACTIONS

G. Hollingworth, J. Sweeney, L. Lee, 1996 .

RADICAL MEDIATED MACROCYCLISATION-TRANSANNULATION CASCADES LEADING TO RING-FUSED LACTONES AND LACTAMS

A. Blake, G. Hollingworth, G. Pattenden, 1996 .

Cascade Radical Cyclization-Fragmentation-Transannular-Ring Expansion Reactions Involving Oximes. A New Approach to Synthesis of Angular Triquinanes

G. Hollingworth, G. Pattenden, D. Schulz, 1995 .

Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G‐quadruplex in K+ Buffer

D. Chin, Steven T. G. Street, M. Berry, 2017, Chemistry.

Novel lactam NK1 antagonists with anti-emetic activity.

K. Tsao, R. Kilburn, C. Swain, 2006, Bioorganic & medicinal chemistry letters.

4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists II.

K. Tsao, C. Swain, G. Hollingworth, 2002, Bioorganic & medicinal chemistry letters.

A Convenient Method for the Preparation of Aryl Cyclopropyl Ethers from Phenols

C. Swain, G. Hollingworth, J. Kulagowski, 1999 .

Synthetic studies towards amphidinolide A. A concise synthesis of the unique ene-tetrol unit from a methyl α-D-glucopyranoside

G. Hollingworth, G. Pattenden, 1998 .

Functional Properties of the High-Affinity TRPV1 (VR1) Vanilloid Receptor Antagonist (4-Hydroxy-5-iodo-3-methoxyphenylacetate ester) Iodo-Resiniferatoxin

S. Teague, S. Boyce, Z. Ali, 2002, Journal of Pharmacology and Experimental Therapeutics.

Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors.

Pascal Furet, Frédéric Stauffer, G. Rummel, 2016, ACS medicinal chemistry letters.

Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension.

N. Waters, E. Vangrevelinghe, G. Hollingworth, 2014, Bioorganic & medicinal chemistry letters.

Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α.

T. Roberts, Jean J. Zhao, S. Maira, 2014, The Journal of clinical investigation.

Imide Condensation as a Strategy for the Synthesis of Core‐Diversified G‐Quadruplex Ligands with Anticancer and Antiparasitic Activity**

Steven T. G. Street, G. Hollingworth, M. Galán, 2020, Chemistry.

Discovery and Toxicological Profiling of Aminopyridines as Orally Bioavailable Selective Inhibitors of PI3-Kinase γ.

Benjamin R Bellenie, G. Hollingworth, M. Bracher, 2021, Journal of medicinal chemistry.

Synthesis of Cleviolide and the Scobinolides.

G. Hollingworth, J. Sweeney, Alexandre M. E. Richecoeur, 2010 .

Modular synthesis and modification of novel bifunctional dendrons.

R. Grotzfeld, Cameron C. Lee, Daniela Miranda, 2019, Organic & biomolecular chemistry.

Real-time imaging and quantification of peptide uptake in vitro and in vivo.

Hacer Karatas, T. Vorherr, G. Hollingworth, 2019, ACS chemical biology.

Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings

M. Schirle, Philipp Holzer, P. Imbach, 2023, bioRxiv.

Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field.

A. Schuffenhauer, Philipp Holzer, N. Schmiedeberg, 2023, ACS Medicinal Chemistry Letters.

Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α.

T. Roberts, Jean J. Zhao, S. Maira, 2014, The Journal of clinical investigation.