A. Donato

发表

S. Tarantini, Z. Ungvari, A. Csiszar, 2018, Circulation research.

The role of senescence, telomere dysfunction and shelterin in vascular aging

A. Donato, Yu Liu, Samuel I Bloom, 2018, Microcirculation.

Attenuated nitric oxide bioavailability in systemic sclerosis: Evidence from the novel assessment of passive leg movement

D. Wray, R. Richardson, T. Frech, 2018, Experimental physiology.

Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down‐regulation of NADPH oxidase

D. Seals, A. Donato, J. Durrant, 2009, The Journal of physiology.

Strategy for Identifying Repurposed Drugs for the Treatment of Cerebral Cavernous Malformation

Weiquan Zhu, Dean Y. Li, C. T. Davis, 2015, Circulation.

Beneficial effects of lifelong caloric restriction on endothelial function are greater in conduit arteries compared to cerebral resistance arteries

A. Donato, L. Lesniewski, Ashley E. Walker, 2013, AGE.

Aging Reduces Skeletal Blood Flow, Endothelium‐Dependent Vasodilation, and NO Bioavailability in Rats

M. Delp, M. Ramsey, R. Prisby, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Weight Loss Alone Improves Conduit and Resistance Artery Endothelial Function in Young and Older Overweight/Obese Adults

S. Beske, G. Pierce, D. Seals, 2008, Hypertension.

Exercise‐induced brachial artery vasodilation: The role of free radicals

D. Bailey, Steven K. Nishiyama, D. Wray, 2007, American journal of physiology. Heart and circulatory physiology.

Salicylate treatment improves age-associated vascular endothelial dysfunction: potential role of nuclear factor kappaB and forkhead Box O phosphorylation.

D. Seals, A. Donato, J. Durrant, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Endogenous endothelin-1 and femoral artery shear rate: impact of age and implications for atherosclerosis

D. Wray, R. Richardson, A. Bledsoe, 2016, Journal of hypertension.

Habitually exercising older men do not demonstrate age‐associated vascular endothelial oxidative stress

G. Pierce, D. Seals, A. Silver, 2011, Aging cell.

INFLUENCE OF HABITUAL EXERCISE AND HORMONE REPLACEMENT THERAPY ON CAROTID ARTERY IMTIMA-MEDIA THICKNESS

K. Moreau, Hirofumi Tanaka, D. Seals, 2001 .

Greater impairments in cerebral artery compared with skeletal muscle feed artery endothelial function in a mouse model of increased large artery stiffness

Dean Y. Li, R. Mecham, Dean Y Li, 2015, The Journal of physiology.

Lifelong SIRT-1 overexpression attenuates large artery stiffening with advancing age

A. Donato, D. Machin, L. Lesniewski, 2020, Aging.

Life‐long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice

D. Seals, A. Donato, Brooke R. Lawson, 2013, Aging cell.

Protein Expression in Vascular Endothelial Cells Obtained from Human Peripheral Arteries and Veins

S. Beske, K. Moreau, D. Seals, 2009, Journal of Vascular Research.

Vascular Endothelial Function Is Related to White Blood Cell Count and Myeloperoxidase Among Healthy Middle-Aged and Older Adults

G. Pierce, D. Seals, A. Donato, 2010, HYPERTENSION.

T cells mediate cell non‐autonomous arterial ageing in mice

Daniel W Trott, A. Donato, Samuel I Bloom, 2021, The Journal of physiology.

Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress.

R. Cawthon, E. L. Denchi, R. Richardson, 2019, Journal of molecular and cellular cardiology.

Telomere uncapping and vascular aging.

A. Donato, Ashley E. Walker, R. G. Morgan, 2018, American journal of physiology. Heart and circulatory physiology.

Daniel W Trott, A. Donato, L. Lesniewski, 2016, Experimental Gerontology.

Selected life‐extending interventions reduce arterial CXCL10 and macrophage colony‐stimulating factor in aged mouse arteries

Daniel W Trott, A. Donato, L. Lesniewski, 2017, Cytokine.

Experimental reduction of miR-92a mimics arterial aging

R. Richardson, S. Hazra, A. Donato, 2016, Experimental Gerontology.

Dichotomous mechanisms of aortic stiffening in high‐fat diet fed young and old B6D2F1 mice

A. Donato, L. Lesniewski, Ashley E. Walker, 2014, Physiological reports.

Aging compounds western diet-associated large artery endothelial dysfunction in mice: Prevention by voluntary aerobic exercise

M. J. Nowlan, D. Seals, A. Donato, 2013, Experimental Gerontology.

Sustained activation of AMPK ameliorates age-associated vascular endothelial dysfunction via a nitric oxide-independent mechanism

D. Seals, Melanie C. Zigler, A. Donato, 2012, Mechanisms of Ageing and Development.

Increased proinflammatory and oxidant gene expression in circulating mononuclear cells in older adults: amelioration by habitual exercise.

G. Pierce, D. Seals, A. Donato, 2011, Physiological genomics.

Short‐term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress

D. Seals, A. Donato, M. L. Connell, 2010, Aging cell.

Human Vascular Aging: Limb-Specific Lessons

Steven K. Nishiyama, D. Wray, R. Richardson, 2010, Exercise and sport sciences reviews.

B6D2F1 Mice are a suitable model of oxidative stress-mediated impaired endothelium-dependent dilation with aging.

D. Seals, A. Donato, J. Durrant, 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

Role of NFκB in age-related vascular endothelial dysfunction in humans

G. Pierce, D. Seals, A. Donato, 2009, Aging.

Physiology of the Aging Vasculature Habitual exercise and arterial aging

Hirofumi Tanaka, D. Seals, C. DeSouza, 2008 .

The effects of aging and exercise training on endothelin-1 vasoconstrictor responses in rat skeletal muscle arterioles.

M. Delp, A. Donato, L. Lesniewski, 2005, Cardiovascular research.

Implications of endothelial shear stress on systemic sclerosis vasculopathy and treatment.

G. Stoddard, M. Murtaugh, T. Frech, 2018, Clinical and experimental rheumatology.

Ageing and exercise training alter adrenergic vasomotor responses of rat skeletal muscle arterioles

M. Delp, A. Donato, L. Lesniewski, 2007, The Journal of physiology.

Influence of ageing and physical activity on vascular morphology in rat skeletal muscle

M. Delp, R. Prisby, A. Donato, 2006, The Journal of physiology.

Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function.

G. Pierce, D. Seals, A. Donato, 2017, American journal of physiology. Heart and circulatory physiology.

Life-long caloric restriction elicits pronounced protection of the aged myocardium: A role for AMPK

D. Seals, A. Edwards, A. Donato, 2010, Mechanisms of Ageing and Development.

Deletion of Robo4 prevents high‐fat diet‐induced adipose artery and systemic metabolic dysfunction

Dean Y. Li, Dean Y Li, A. Donato, 2019, Microcirculation.

Sirt1 overexpression attenuates Western‐style diet‐induced aortic stiffening in mice

A. Donato, Jisok Lim, J. Durrant, 2022, Physiological reports.

Arterial Intima-Media Thickness: Site-Specific Associations with Hormone Replacement Therapy and Habitual Exercise

K. Moreau, Hirofumi Tanaka, D. Seals, 2022 .

concentration in older women Aerobic exercise training reduces plasma endothelin-1

J. Sugawara, S. Kuno, T. Otsuki, 2015 .

Differential Telomere Shortening in Blood versus Arteries in an Animal Model of Type 2 Diabetes

S. Tajbakhsh, D. Hussey, Elke M Sokoya, 2015, Journal of diabetes research.

TNF-α impairs endothelial function in adipose tissue resistance arteries of mice with diet-induced obesity.

A. Donato, L. Lesniewski, Ashley E. Walker, 2012, American journal of physiology. Heart and circulatory physiology.

R. Cawthon, R. Richardson, R. Andtbacka, 2016, Experimental Gerontology.

SIRT‐1 and vascular endothelial dysfunction with ageing in mice and humans

D. Seals, A. Donato, J. Durrant, 2011, The Journal of physiology.

T lymphocyte depletion ameliorates age-related metabolic impairments in mice

D. J. Buckley, Daniel W Trott, A. Donato, 2021, GeroScience.

Systemic sclerosis induces pronounced peripheral vascular dysfunction characterized by blunted peripheral vasoreactivity and endothelial dysfunction

P. Hopkins, D. Wray, R. Richardson, 2015, Clinical Rheumatology.

Exercise-induced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men.

D. Bailey, D. Wray, R. Richardson, 2010, American journal of physiology. Heart and circulatory physiology.

Exercise-induced brachial artery vasodilation : 1 Effects of antioxidants and exercise training in elderly men 2 3 4 5 6 7

D. Bailey, D. Wray, A. Donato, 2009 .

Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase.

D. Seals, A. Silver, P. Gates, 2009, American journal of physiology. Heart and circulatory physiology.

Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans.

G. Pierce, D. Seals, A. Donato, 2008, Journal of applied physiology.

The Paradox of Oxidative Stress and Exercise With Advancing Age

P. Carlier, D. Bailey, D. Wray, 2011, Exercise and sport sciences reviews.

Mechanisms and consequences of endothelial cell senescence

A. Donato, L. Lesniewski, M. Islam, 2022, Nature Reviews Cardiology.

Tetrahydrobiopterin Administration Augments Exercise-Induced Hyperemia and Endothelial Function in Patients With Systemic Sclerosis

T. Frech, A. Donato, D. Wray, 2022, Frontiers in Medicine.

Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping

R. Cawthon, R. Richardson, R. Andtbacka, 2014, Journal of hypertension.

Role of NFkappaB in age-related vascular endothelial dysfunction in humans.

G. Pierce, D. Seals, A. Donato, 2009 .

Exercise-induced brachial artery blood flow and vascular function is impaired in systemic sclerosis.

R. Garten, D. Wray, R. Richardson, 2016, American journal of physiology. Heart and circulatory physiology.

radicals brachial artery vasodilation: role of free

D. Bailey, D. Wray, R. Richardson, 2016 .

Cerebral and skeletal muscle feed artery vasoconstrictor responses in a mouse model with greater large elastic artery stiffness

Dean Y. Li, Dean Y Li, A. Donato, 2019, Experimental physiology.

Endogenous endothelin-1 and femoral artery shear rate: impact of age and implications for atherosclerosis

D. Wray, R. Richardson, A. Bledsoe, 2015, Journal of hypertension.

Smooth muscle specific disruption of the endothelin-A receptor in mice reduces arterial pressure, and vascular reactivity and affects vascular development.

Dean Y. Li, D. Kohan, Dean Y Li, 2014, Life sciences.

Acute sympathetic vasoconstriction at rest and during dynamic exercise in cyclists and sedentary humans.

D. Wray, R. Richardson, A. Donato, 2007, Journal of applied physiology.

Use of acetylene breathing to determine cardiac output in young and older adults.

K. Beck, D. Seals, K. Monahan, 2003, Medicine and science in sports and exercise.

Effects of aging, TNF-α, and exercise training on angiotensin II-induced vasoconstriction of rat skeletal muscle arterioles.

M. Delp, R. Prisby, J. Muller-Delp, 2012, Journal of applied physiology.

Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium

Dean Y. Li, C. T. Davis, C. C. Gibson, 2015, PloS one.

Acute oral tetrahydrobiopterin administration ameliorates endothelial dysfunction in systemic sclerosis.

D. Wray, R. Richardson, T. Frech, 2017, Clinical and experimental rheumatology.

Large artery stiffening and mortality in a rat model of early vascular remodeling induced by intrauterine growth restriction and a high‐fat diet

T. Miller, R. McKnight, Anastasiya Mankouski, 2022, Physiological reports.

Automated Measurement of Microvascular Function Reveals Dysfunction in Systemic Sclerosis: A Cross-sectional Study

T. Frech, P. Gates, A. Donato, 2017, The Journal of Rheumatology.

Systemic Sclerosis : A Cross-sectional Study Automated Measurement of Microvascular Function Reveals Dysfunction in

T. Frech, P. Gates, A. Donato, 2017 .

Ageing and vascular adrenoceptor desensitization: too little, too late?

A. Donato, 2007, The Journal of physiology.

Human skeletal muscle feed arteries: evidence of regulatory potential

R. Richardson, R. Andtbacka, A. Donato, 2012, Acta physiologica.

James Stray-Gundersen performance acclimatization with low-altitude training on ' ' Living high-training low ' ' : effect of moderate-altitude

Alain, Bruce D. Johnson, Matthew R. Ely, 2016 .

The role of the endothelial glycocalyx in advanced age and cardiovascular disease.

A. Donato, D. Machin, Tam T. T. Phuong, 2019, Current opinion in pharmacology.

Aerobic exercise reverses arterial inflammation with aging in mice.

Douglas R Seals, D. Seals, A. Donato, 2011, American journal of physiology. Heart and circulatory physiology.

Habitual exercise and arterial aging.

Hirofumi Tanaka, Douglas R Seals, Hirofumi Tanaka, 2008, Journal of applied physiology.

Direct Evidence of Endothelial Oxidative Stress With Aging in Humans: Relation to Impaired Endothelium-Dependent Dilation and Upregulation of Nuclear Factor-&kgr;B

G. Pierce, D. Seals, A. Silver, 2007, Circulation research.

Cellular aging of skeletal muscle: telomeric and free radical evidence that physical inactivity is responsible and not age.

R. Cawthon, F. Schena, C. Reggiani, 2014, Clinical science.

Cellular and molecular biology of aging endothelial cells.

A. Donato, L. Lesniewski, Ashley E. Walker, 2015, Journal of molecular and cellular cardiology.

R. Cawthon, R. Richardson, R. Andtbacka, 2013, American journal of physiology. Heart and circulatory physiology.

Aging is associated with greater nuclear NFκB, reduced IκBα, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans

D. Seals, Anthony J. Donato, Alexander D. Black, 2008, Aging cell.

Mechanisms of Dysfunction in the Aging Vasculature and Role in Age-Related Disease

A. Donato, D. Machin, L. Lesniewski, 2018, Circulation research.

MicroRNA changes in human arterial endothelial cells with senescence: Relation to apoptosis, eNOS and inflammation

D. Seals, A. Donato, Brooke R. Lawson, 2012, Experimental Gerontology.

Advanced age results in a diminished endothelial glycocalyx.

Robert A. Campbell, M. Rondina, P. Gates, 2018, American journal of physiology. Heart and circulatory physiology.

and mechanical properties of the vessel wall femoral arteries: role of contractile protein expression Simulated microgravity effects on the rat carotid and

Xi-qing Sun, Shiqiang Yu, Dinghua Yi, 2015 .

Aging and vascular endothelial function in humans.

Douglas R Seals, D. Seals, A. Donato, 2011, Clinical science.

Age-Associated ALU Element Instability in White Blood Cells Is Linked to Lower Survival in Elderly Adults: A Preliminary Cohort Study

F. Schena, C. Reggiani, R. Richardson, 2017, PloS one.

Simulated microgravity alters rat mesenteric artery vasoconstrictor dynamics through an intracellular Ca(2+) release mechanism.

M. Delp, M. K. Wilkerson, P. Colleran, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.

R. Zechner, N. Longo, U. Apte, 2017, Cell metabolism.

Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease

G. Porter, S. Tsaih, M. Flister, 2019, Scientific Reports.

Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation

Julie K. Freed, D. Gutterman, M. Riedel, 2016, Circulation research.

exercise in humans Antioxidants attenuate the plasma cytokine response to

C. Roussos, G. Pierce, D. Seals, 2015 .

Overweight and Obese Humans Demonstrate Increased Vascular Endothelial NAD(P)H Oxidase-p47phox Expression and Evidence of Endothelial Oxidative Stress

S. Beske, K. Moreau, D. Seals, 2007, Circulation.

The impact of ageing on adipose structure, function and vasculature in the B6D2F1 mouse: evidence of significant multisystem dysfunction

S. Hazra, J. Trinity, A. Donato, 2014, The Journal of physiology.

A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes.

Lik Hang Yuen, Dario Neri, Dmitri Kireev, 2019, Journal of the American Chemical Society.

The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice.

D. Seals, A. Donato, C. Hearon, 2014, American journal of physiology. Heart and circulatory physiology.

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats.

Hirofumi Tanaka, Y. Shiu, A. Donato, 2016, Journal of visualized experiments : JoVE.

Endothelin-A-mediated vasoconstriction during exercise with advancing age.

D. Wray, R. Richardson, A. Bledsoe, 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

Is It Good to Have a Stiff Aorta with Aging? Causes and Consequences.

G. Pierce, A. Donato, Lyndsey E. DuBose, 2021, Physiology.

Arterial intima-media thickness: site-specific associations with HRT and habitual exercise.

K. Moreau, Hirofumi Tanaka, D. Seals, 2002, American journal of physiology. Heart and circulatory physiology.

Basal leg blood flow in healthy women is related to age and hormone replacement therapy status.

K. Moreau, Hirofumi Tanaka, D. Seals, 2003, The Journal of physiology.

Basal leg blood flow in healthy women is related to age and hormone replacement therapy status

K. Moreau, Hirofumi Tanaka, D. Seals, 2003 .

Aging differentially impacts vasodilation and angiogenesis in arteries from the white and brown adipose tissues

A. Donato, D. Machin, L. Lesniewski, 2020, Experimental Gerontology.

High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men.

D. Seals, K. Monahan, A. Donato, 2007, Journal of applied physiology.

Differential effects of aging on limb blood flow in humans.

D. Wray, R. Richardson, A. Donato, 2006, American journal of physiology. Heart and circulatory physiology.

Endothelin-1-mediated vasoconstriction at rest and during dynamic exercise in healthy humans.

P. Wagner, D. Wray, R. Richardson, 2007, American journal of physiology. Heart and circulatory physiology.

Dietary rapamycin supplementation reverses age‐related vascular dysfunction and oxidative stress, while modulating nutrient‐sensing, cell cycle, and senescence pathways

D. Seals, Melanie C. Zigler, Daniel W Trott, 2016, Aging cell.

Regular exercise, hormone replacement therapy and the age-related decline in carotid arterial compliance in healthy women.

K. Moreau, Hirofumi Tanaka, D. Seals, 2003, Cardiovascular research.

Global analysis of plasma lipids identifies liver-derived acyl-carnitines as a fuel source for brown fat thermogenesis

N. Longo, U. Apte, J. Rutter, 2017, bioRxiv.

The pro-atherogenic response to disturbed blood flow is increased by a western diet, but not by old age

A. Donato, D. Machin, J. Durrant, 2019, Scientific Reports.

Changes in maximal aerobic capacity with age in endurance-trained women: 7-yr follow-up.

K. Moreau, Hirofumi Tanaka, D. Seals, 2002, Journal of applied physiology.

Effects of aging and exercise training on structural and vasoconstrictor properties of skeletal muscle arterioles

A. Donato, 2004 .

Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age

Daniel W Trott, A. Donato, L. Lesniewski, 2023, Aging cell.

Taming the "sleeping giant": the role of endothelin-1 in the regulation of skeletal muscle blood flow and arterial blood pressure during exercise.

D. Wray, R. Richardson, A. Bledsoe, 2013, American journal of physiology. Heart and circulatory physiology.

sedentary and exercise-trained rats Vasomotor responses of soleus feed arteries from

M. Delp, Jeffrey S. Martin, M. Laughlin, 2015 .

Effects of ageing and exercise training on endothelium‐dependent vasodilatation and structure of rat skeletal muscle arterioles

M. Delp, M. Ramsey, C. Meininger, 2004, The Journal of physiology.

Reduced large elastic artery stiffness with regular aerobic exercise in middle-aged and older adults: potential role of suppressed nuclear factor &kgr; B signalling

M. J. Nowlan, Bradley S. Fleenor, D. Seals, 2015, Journal of hypertension.

Endothelial specific reduction in Arf6 impairs insulin-stimulated vasodilation and skeletal muscle blood flow resulting in systemic insulin resistance

A. Donato, L. Lesniewski, Weiquan Zhu, 2023, bioRxiv.

Exercise training reverses aging-induced impairment of myogenic constriction in skeletal muscle arterioles.

M. Delp, J. Muller-Delp, A. Donato, 2015, Journal of applied physiology.

Aging results in DNA damage and telomere dysfunction that is greater in endothelial versus vascular smooth muscle cells and is exacerbated in atheroprone regions.

A. Donato, Jisok Lim, L. Lesniewski, 2022, GeroScience.

Beneficial effects of lifelong caloric restriction on endothelial function are greater in conduit arteries compared to cerebral resistance arteries

A. Donato, L. Lesniewski, Ashley E. Walker, 2014, AGE.

flowinfluence of aging on exercising leg blood

B. Parker, D. Proctor, R. Richardson, 2015 .

Heterozygosity for ADP-ribosylation factor 6 suppresses the burden and severity of atherosclerosis

Daniel W Trott, A. Donato, J. Durrant, 2023, PloS one.

Onset exercise hyperaemia in humans: partitioning the contributors

D. Wray, R. Richardson, A. Donato, 2005, The Journal of physiology.

K. Moreau, Hirofumi Tanaka, M. Miyachi, 2003, Hypertension.

Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease

G. Porter, S. Tsaih, M. Flister, 2019, Scientific Reports.

Glycocalyx-targeted therapy ameliorates age-related arterial dysfunction

Daniel W Trott, A. Donato, L. Lesniewski, 2023, GeroScience.

Declines in physiological functional capacity with age: a longitudinal study in peak swimming performance.

Hirofumi Tanaka, D. Seals, D. Glueck, 2003, Journal of applied physiology.

capacity: insight from swimming performance Age and gender interactions in physiological functional

Hirofumi Tanaka, D. Seals, D. Glueck, 2005 .

Cerebrovascular dysfunction following subfailure axial stretch.

K. Monson, A. Donato, E. D. Bell, 2017, Journal of the mechanical behavior of biomedical materials.

pressure during exercise the regulation of skeletal muscle blood flow and arterial Taming the ' ' sleeping giant ' ' : the role of endothelin-1 in

Rossman, Blood, D. Wray, 2012 .

Analysis of Somatic Mutations in Senescent Cells Using Single-Cell Whole-Genome Sequencing

A. Donato, L. Lesniewski, Eric Tuday, 2023, Aging Biology.

Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension.

M. Delp, C. Ray, A. Donato, 2008, American journal of physiology. Heart and circulatory physiology.

Impact of high-fat diet on vasoconstrictor reactivity of white and brown adipose tissue resistance arteries.

S. Hazra, A. Donato, L. Lesniewski, 2019, American journal of physiology. Heart and circulatory physiology.

Telomere uncapping causes cellular senescence and inflammation in arteries: implications for arterial aging

R. Cawthon, E. L. Denchi, A. Donato, 2013 .

Senolytic Drugs, Dasatinib and Quercetin, Attenuate Adipose Tissue T Lymphocyte Infiltration and Improve Metabolic Function in Old Mice

A. Donato, L. Lesniewski, Eric Tuday, 2021, The FASEB Journal.

Sirt1 overexpression attenuates high-fat diet induced aortic stiffening

A. Donato, D. Machin, L. Lesniewski, 2020, bioRxiv.

The pro-atherogenic response to disturbed blood flow is increased by a western diet, but not by old age

A. Donato, D. Machin, J. Durrant, 2019, Scientific Reports.

Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments

A. Donato, L. Lesniewski, Yu Liu, 2023, Aging cell.

Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans.

G. Pierce, D. Seals, A. Donato, 2008, Journal of applied physiology.

B6D2F1 Mice are a suitable model of oxidative stress-mediated impaired endothelium-dependent dilation with aging.

D. Seals, A. Donato, J. Durrant, 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

Cellular and molecular biology of aging endothelial cells.

A. Donato, L. Lesniewski, Ashley E. Walker, 2015, Journal of molecular and cellular cardiology.

The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice.

D. Seals, A. Donato, C. Hearon, 2014, American journal of physiology. Heart and circulatory physiology.

Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function.

G. Pierce, D. Seals, A. Donato, 2017, American journal of physiology. Heart and circulatory physiology.

Simulated microgravity alters rat mesenteric artery vasoconstrictor dynamics through an intracellular Ca(2+) release mechanism.

M. Delp, M. K. Wilkerson, P. Colleran, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Commentaries on Viewpoint : The two-hour marathon : Who and when ?

C. Capelli, T. Stellingwerff, S. Perrey, 2010 .

a longitudinal study in peak swimming performance Declines in physiological functional capacity with age

Hirofumi Tanaka, D. Seals, D. Glueck, 2005 .

Advanced age results in a diminished endothelial glycocalyx.

Robert A. Campbell, M. Rondina, P. Gates, 2018, American journal of physiology. Heart and circulatory physiology.

Aged endothelial cells exhibit a metabolic shift from anaerobic glycolysis to oxidative phosphorylation

P. Gates, A. Donato, L. Lesniewski, 2019, The FASEB Journal.

Greater impairments in cerebral artery compared with skeletal muscle feed artery endothelial function in a mouse model of increased large artery stiffness

R. Mecham, Dean Y Li, A. Donato, 2015, The Journal of physiology.

Therapeutic strategies targeting the endothelial glycocalyx

A. Donato, Xiangyu Zheng, Mostafa Sabouri, 2023, Current opinion in clinical nutrition and metabolic care.