Khoa Le

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Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows

D. Burton, I. Wilson, A. Ward, 2017, Nature.

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies

Daphne Koller, George M. Church, Jonathan Laserson, 2013, PLoS pathogens.

Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo.

Todd M. Allen, T. Allen, D. Burton, 2016, Journal of Infectious Diseases.

Very Few Substitutions in a Germ Line Antibody Are Required To Initiate Significant Domain Exchange

D. Burton, I. Wilson, Z. Fulton, 2010, Journal of Virology.

Protective Efficacy of Broadly Neutralizing Antibodies with Incomplete Neutralization Activity against Simian-Human Immunodeficiency Virus in Rhesus Monkeys

Ruchi M. Newman, Todd M. Allen, T. Allen, 2017, Journal of Virology.

Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques

Andrew P. Hodges, A. Godzik, D. Burton, 2016, AIDS.

Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults

Erin E. Gill, R. Scheuermann, D. Burton, 2020, Frontiers in Immunology.

Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques

D. Burton, D. Watkins, R. Desrosiers, 2017, Science Translational Medicine.

Overline : Emerging infections One Sentence Summary : Neutralizing antibodies prevent Zika infection

D. Burton, D. Watkins, R. Desrosiers, 2022 .

2G12-Expressing B Cell Lines May Aid in HIV Carbohydrate Vaccine Design Strategies

D. Burton, Chi‐Huey Wong, D. Nemazee, 2012, Journal of Virology.

Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies

D. Burton, D. Watkins, J. Lifson, 2020, Molecular therapy. Methods & clinical development.

Clonify: unseeded antibody lineage assignment from next-generation sequencing data

Dennis R. Burton, Bryan Briney, D. Burton, 2016, Scientific Reports.

Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes.

J. Sodroski, B. Haynes, D. Burton, 2015, Virology.

Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for the SIVsmm/mac Envelope Glycoprotein Uncouple Antibody-Dependent Cellular Cytotoxicity from Neutralization

D. Burton, J. Pallesen, A. Ward, 2019, mBio.

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

David Nemazee, Joseph G. Jardine, Oleksandr Kalyuzhniy, 2016, Cell.

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

D. Burton, H. Schuitemaker, T. Wrin, 2015, PLoS pathogens.

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

Yan Liu, Ryan McBride, Robyn L. Stanfield, 2013, Nature Structural &Molecular Biology.

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

John P. Moore, D. Burton, B. Briney, 2014, Proceedings of the National Academy of Sciences.

Comparison of Antibody-Dependent Cell-Mediated Cytotoxicity and Virus Neutralization by HIV-1 Env-Specific Monoclonal Antibodies

S. Zolla-Pazner, D. Burton, James E. Robinson, 2016, Journal of Virology.

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers.

Wayne C Koff, Chung-Yi Wu, Chi-Huey Wong, 2014, Immunity.

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

B. Korber, J. Mascola, D. Burton, 2017, Science Translational Medicine.

Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope

D. Burton, I. Wilson, Uri Laserson, 2014, Journal of Virology.

B Cells from Knock-in Mice Expressing Broadly Neutralizing HIV Antibody b12 Carry an Innocuous B Cell Receptor Responsive to HIV Vaccine Candidates

R. Wyatt, D. Burton, W. Schief, 2013, The Journal of Immunology.

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

Daniel W. Kulp, D. Burton, A. Bradley, 2016, Science.

Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors

Bryan Briney, Nathan Beutler, Dennis R Burton, 2017, Science Immunology.

Anti-HIV B Cell Lines as Candidate Vaccine Biosensors

J. Mascola, J. Binley, R. Wyatt, 2012, The Journal of Immunology.

A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.

D. Burton, I. Wilson, Chi‐Huey Wong, 2016, Immunity.

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer.

Jennifer S. Wood, B. Pulendran, John P. Moore, 2016, Cell reports.

Reprogramming the antigen specificity of B cells using genome-editing technologies

David Nemazee, Ben Murrell, Bryan Briney, 2018, bioRxiv.

Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Broadens Neutralization of HIV

William R. Schief, Michael S. Seaman, Dennis R. Burton, 2014, Science Translational Medicine.

Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies

D. Burton, T. Wrin, P. Poignard, 2016, Retrovirology.

Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques

Andrew P. Hodges, A. Godzik, D. Burton, 2016, AIDS.

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

John P. Moore, D. Burton, A. Ward, 2014, Proceedings of the National Academy of Sciences.

Diverse competitor B cell responses to a germline-targeting priming immunogen in human Ig loci transgenic mice

Daniel W. Kulp, J. Diedrich, W. Schief, 2024, bioRxiv.