Thibaut Pelat

发表

Germline humanization of a non-human primate antibody that neutralizes the anthrax toxin, by in vitro and in silico engineering.

A. Rees, M. Lefranc, S. Crennell, 2008, Journal of molecular biology.

Isolation of a human-like antibody fragment (scFv) that neutralizes ricin biological activity

S. Dübel, M. Lefranc, M. Hust, 2009, BMC biotechnology.

Development of a drug delivery system for efficient alveolar delivery of a neutralizing monoclonal antibody to treat pulmonary intoxication to ricin.

K. Tchou-Wong, N. Heuzé-Vourc’h, L. Douziech-Eyrolles, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Effect of formulation on the stability and aerosol performance of a nebulized antibody

Renaud Respaud, Laurent Vecellio, Jean-François Tournamille, 2014, mAbs.

Human-like antibodies neutralizing Western equine encephalitis virus

S. Dübel, T. Schirrmann, M. Hust, 2014, mAbs.

Development of Human and Macaque Antibodies Using Antibody Phage Display for the Detection of Equine Encephalitis Viruses

S. Dübel, M. Hust, Thibaut Pelat, 2011 .

The European AntibotABE Framework Program and Its Update: Development of Innovative Botulinum Antibodies

H. Korkeala, M. Hust, D. Sesardic, 2017, Toxins.

A comparison of human and macaque (Macaca mulatta) immunoglobulin germline V regions and its implications for antibody engineering

Thibaut Pelat, P. Thullier, S. Chahboun, 2010, mAbs.

Construction of Macaque Immune-Libraries.

M. Hust, Thibaut Pelat, Sebastian Miethe, 2018, Methods in molecular biology.

Development of Human-Like scFv-Fc Neutralizing Botulinum Neurotoxin E

H. Korkeala, M. Hust, D. Sesardic, 2015, PloS one.

Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library

T. Schirrmann, M. Hust, A. Frenzel, 2014, mAbs.

Isolation of a nanomolar scFv inhibiting the endopeptidase activity of botulinum toxin A, by single-round panning of an immune phage-displayed library of macaque origin

M. Hust, D. Sesardic, Thibaut Pelat, 2011, BMC biotechnology.

Development of AntiToxins Antibodies for Biodefense

Thibaut Pelat, P. Thullier, J. Mathieu, 2011 .

Development of Anti-Toxins Antibodies for Biodefense

Thibaut Pelat, P. Thullier, J. Mathieu, 2011 .

Neutralization of Botulinum Neurotoxin Type E by a Humanized Antibody

M. Lindström, H. Korkeala, M. Hust, 2016, Toxins.

Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B

R. Tierney, M. Hust, A. Frenzel, 2016, PloS one.

Immune Libraries from Nonhuman Primates (NHP)

M. Hust, Thibaut Pelat, P. Thullier, 2010 .

Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A1 and A2 by targeting their heavy chain

M. Hust, D. Sesardic, M. Popoff, 2015, BMC Biotechnology.

Anticorps et bioterrorisme

D. Vidal, Thibaut Pelat, P. Thullier, 2009 .

Generation and characterization of protective antibodies to Marburg virus

Samantha E. Zak, J. Dye, K. Chandran, 2017, mAbs.

High-Affinity, Human Antibody-Like Antibody Fragment (Single-Chain Variable Fragment) Neutralizing the Lethal Factor (LF) of Bacillus anthracis by Inhibiting Protective Antigen-LF Complex Formation

S. Dübel, M. Lefranc, M. Hust, 2007, Antimicrobial Agents and Chemotherapy.

Identification of a Putative Crf Splice Variant and Generation of Recombinant Antibodies for the Specific Detection of Aspergillus fumigatus

S. Dübel, M. Gunzer, T. Schirrmann, 2009, PloS one.

Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail

Samantha E. Zak, J. Dye, A. Herbert, 2018, Viruses.

Structural differences of amyloid-β fibrils revealed by antibodies from phage display

S. Dübel, H. Lashuel, M. Hust, 2015, BMC Biotechnology.

Non-human primate immune libraries combined with germline humanization

Thibaut Pelat, P. Thullier, 2009, mAbs.

Antibodies for biodefense

B. Stiles, Jeffrey W. Froude, Thibaut Pelat, 2011, mAbs.

Mapping the Epitopes of a Neutralizing Antibody Fragment Directed against the Lethal Factor of Bacillus anthracis and Cross-Reacting with the Homologous Edema Factor

J. Pellequer, Thibaut Pelat, P. Thullier, 2013, PloS one.

Antibodies Against Anthrax: Mechanisms of Action and Clinical Applications

Jeffrey W. Froude, Thibaut Pelat, P. Thullier, 2011, Toxins.

Obtention and engineering of non-human primate (NHP) antibodies for therapeutics.

M. Hust, Thibaut Pelat, P. Thullier, 2009, Mini reviews in medicinal chemistry.

Detection of Antiranibizumab Antibodies among Patients with Exudative Age-Related Macular Degeneration

E. Souied, N. Leveziel, H. Watier, 2014, Ophthalmologica.

Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B

R. Tierney, M. Hust, D. Sesardic, 2015, mAbs.

Antibodies against Anthrax Toxins: A Long Way from Benchlab to the Bedside

J. Tournier, Thibaut Pelat, P. Thullier, 2022, Toxins.

The humanness of macaque antibody sequences.

Andrew C. R. Martin, Thibaut Pelat, P. Thullier, 2010, Journal of molecular biology.

Generation and characterization of protective antibodies to Marburg virus

Samantha E. Zak, J. Dye, K. Chandran, 2017, mAbs.

Isolation of antibodies from non-human primates for clinical use.

Jeffrey W. Froude, Thibaut Pelat, P. Thullier, 2014, Current drug discovery technologies.

Isolation and Characterisation of a Human-Like Antibody Fragment (scFv) That Inactivates VEEV In Vitro and In Vivo

S. Dübel, T. Schirrmann, M. Hust, 2012, PloS one.