P. Thullier

发表

Germline humanization of a non-human primate antibody that neutralizes the anthrax toxin, by in vitro and in silico engineering.

A. Rees, M. Lefranc, S. Crennell, 2008, Journal of molecular biology.

A high-affinity macaque antibody Fab with human-like framework regions obtained from a small phage display immune library.

Marie-Paule Lefranc, M. Lefranc, E. Drouet, 2004, Molecular immunology.

Isolation of a human-like antibody fragment (scFv) that neutralizes ricin biological activity

S. Dübel, M. Lefranc, M. Hust, 2009, BMC biotechnology.

Development of a drug delivery system for efficient alveolar delivery of a neutralizing monoclonal antibody to treat pulmonary intoxication to ricin.

K. Tchou-Wong, N. Heuzé-Vourc’h, L. Douziech-Eyrolles, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Effect of formulation on the stability and aerosol performance of a nebulized antibody

Renaud Respaud, Laurent Vecellio, Jean-François Tournamille, 2014, mAbs.

long-term follow-up of hematopoiesis after irradiation prevents nonhuman primates from myelosuppression: growth and development factor, and interleukin-3 in combination soon Single administration of stem cell factor, FLT-3 ligand, megakaryocyte

M. Drouet, P. Thullier, F. Hérodin, 2013 .

Human-like antibodies neutralizing Western equine encephalitis virus

S. Dübel, T. Schirrmann, M. Hust, 2014, mAbs.

Development of Human and Macaque Antibodies Using Antibody Phage Display for the Detection of Equine Encephalitis Viruses

S. Dübel, M. Hust, Thibaut Pelat, 2011 .

The European AntibotABE Framework Program and Its Update: Development of Innovative Botulinum Antibodies

H. Korkeala, M. Hust, D. Sesardic, 2017, Toxins.

A comparison of human and macaque (Macaca mulatta) immunoglobulin germline V regions and its implications for antibody engineering

Thibaut Pelat, P. Thullier, S. Chahboun, 2010, mAbs.

An Immunochromatographic Test for the Diagnosis of Ricin Inhalational Poisoning

W. Splettstoesser, P. Thullier, V. Guglielmo-Viret, 2007, Clinical toxicology.

Development of Human-Like scFv-Fc Neutralizing Botulinum Neurotoxin E

H. Korkeala, M. Hust, D. Sesardic, 2015, PloS one.

Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library

T. Schirrmann, M. Hust, A. Frenzel, 2014, mAbs.

Isolation of a nanomolar scFv inhibiting the endopeptidase activity of botulinum toxin A, by single-round panning of an immune phage-displayed library of macaque origin

M. Hust, D. Sesardic, Thibaut Pelat, 2011, BMC biotechnology.

Development of AntiToxins Antibodies for Biodefense

Thibaut Pelat, P. Thullier, J. Mathieu, 2011 .

Development of Anti-Toxins Antibodies for Biodefense

Thibaut Pelat, P. Thullier, J. Mathieu, 2011 .

Neutralization of Botulinum Neurotoxin Type E by a Humanized Antibody

M. Lindström, H. Korkeala, M. Hust, 2016, Toxins.

Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B

R. Tierney, M. Hust, A. Frenzel, 2016, PloS one.

Immune Libraries from Nonhuman Primates (NHP)

M. Hust, Thibaut Pelat, P. Thullier, 2010 .

Comparison of electrochemiluminescence assay and ELISA for the detection of Clostridium botulinum type B neurotoxin.

O. Attrée, P. Thullier, V. Guglielmo-Viret, 2005, Journal of immunological methods.

Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A1 and A2 by targeting their heavy chain

M. Hust, D. Sesardic, M. Popoff, 2015, BMC Biotechnology.

Comparison of Hand-Held Test Kits, Immunofluorescence Microscopy, Enzyme-Linked Immunosorbent Assay, and Flow Cytometric Analysis for Rapid Presumptive Identification of Yersinia pestis

L. Rahalison, H. Neubauer, H. Tomaso, 2007, Journal of Clinical Microbiology.

Nonhuman primates are relevant models for research in hematology, immunology and virology.

M. Drouet, P. Thullier, F. Hérodin, 2005, European cytokine network.

Selection of a Macaque Fab with Framework Regions Like Those in Humans, High Affinity, and Ability To Neutralize the Protective Antigen (PA) of Bacillus anthracis by Binding to the Segment of PA between Residues 686 and 694

M. Lefranc, D. Vidal, E. Drouet, 2005, Antimicrobial Agents and Chemotherapy.

Comparison of an electrochemiluminescence assay in plate format over a colorimetric ELISA, for the detection of ricin B chain (RCA-B).

P. Thullier, V. Guglielmo-Viret, 2007, Journal of immunological methods.

Generation and characterization of protective antibodies to Marburg virus

Samantha E. Zak, J. Dye, K. Chandran, 2017, mAbs.

Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus

M. Delepierre, A. Urvoas, H. Bedouelle, 2006, The FEBS journal.

A recombinant Fab neutralizes dengue virus in vitro

V. Deubel, A. Jouan, F. Mégret, 1999, Journal of Biotechnology.

High-Affinity, Human Antibody-Like Antibody Fragment (Single-Chain Variable Fragment) Neutralizing the Lethal Factor (LF) of Bacillus anthracis by Inhibiting Protective Antigen-LF Complex Formation

S. Dübel, M. Lefranc, M. Hust, 2007, Antimicrobial Agents and Chemotherapy.

Identification of a Putative Crf Splice Variant and Generation of Recombinant Antibodies for the Specific Detection of Aspergillus fumigatus

S. Dübel, M. Gunzer, T. Schirrmann, 2009, PloS one.

Evaluation of an Immunochromatographic Test for Rapid and Reliable Serodiagnosis of Human Tularemia and Detection of Francisella tularensis-Specific Antibodies in Sera from Different Mammalian Species

W. Splettstoesser, P. Thullier, E. Seibold, 2010, Journal of Clinical Microbiology.

Evaluation of an immunochromatographic test ( ICT ) for the rapid and reliable serodiagnosis of human tularemia and the detection of F . tularensis-specific antibodies in serum from different mammalian species

W. Splettstoesser, P. Thullier, E. Seibold, 2010 .

Lessons Learned about Pneumonic Plague Diagnosis from 2 Outbreaks, Democratic Republic of the Congo

P. Formenty, E. Bertherat, L. Rahalison, 2011, Emerging infectious diseases.

Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail

Samantha E. Zak, J. Dye, A. Herbert, 2018, Viruses.

Single administration of stem cell factor, FLT-3 ligand, megakaryocyte growth and development factor, and interleukin-3 in combination soon after irradiation prevents nonhuman primates from myelosuppression: long-term follow-up of hematopoiesis.

Michel Drouet, M. Drouet, J. Mayol, 2004, Blood.

Structural differences of amyloid-β fibrils revealed by antibodies from phage display

S. Dübel, H. Lashuel, M. Hust, 2015, BMC Biotechnology.

Short report: Serodiagnosis of plague in humans and rats using a rapid test.

S. Chanteau, P. Thullier, M. Rajerison, 2003, The American journal of tropical medicine and hygiene.

Non-human primate immune libraries combined with germline humanization

Thibaut Pelat, P. Thullier, 2009, mAbs.

Antibodies for biodefense

B. Stiles, Jeffrey W. Froude, Thibaut Pelat, 2011, mAbs.

Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism.

H. Bedouelle, C. Demangel, V. Deubel, 2001, The Journal of general virology.

Mapping the Epitopes of a Neutralizing Antibody Fragment Directed against the Lethal Factor of Bacillus anthracis and Cross-Reacting with the Homologous Edema Factor

J. Pellequer, Thibaut Pelat, P. Thullier, 2013, PloS one.

Development and comparison of two immunoassay formats for rapid detection of botulinum neurotoxin type A.

Valérie Gros, V. Gros, O. Attrée, 2007, Journal of immunological methods.

Antibodies Against Anthrax: Mechanisms of Action and Clinical Applications

Jeffrey W. Froude, Thibaut Pelat, P. Thullier, 2011, Toxins.

Obtention and engineering of non-human primate (NHP) antibodies for therapeutics.

M. Hust, Thibaut Pelat, P. Thullier, 2009, Mini reviews in medicinal chemistry.

Detection of Antiranibizumab Antibodies among Patients with Exudative Age-Related Macular Degeneration

E. Souied, N. Leveziel, H. Watier, 2014, Ophthalmologica.

Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B

R. Tierney, M. Hust, D. Sesardic, 2015, mAbs.

Evaluation by ELISA of Ricin Concentration in Fluids and Tissues after Exposure to Aerosolised Ricin, and Evaluation of anImmunochromatographic Test for Field Diagnosis

G. Griffiths, P. Thullier, J. Holley, 2013 .

Combination of cultivation and lateral flow assay for easy, highly sensitive and presumptive detection of Bacillus anthracis spores

N. Vietri, P. Thullier, V. Guglielmo-Viret, 2011 .

Broad recognition of ricin toxins prepared from a range of Ricinus cultivars using immunochromatographic tests

G. Griffiths, P. Thullier, 2009, Clinical toxicology.

Antibodies against Anthrax Toxins: A Long Way from Benchlab to the Bedside

J. Tournier, Thibaut Pelat, P. Thullier, 2022, Toxins.

The humanness of macaque antibody sequences.

Andrew C. R. Martin, Thibaut Pelat, P. Thullier, 2010, Journal of molecular biology.

Generation and characterization of protective antibodies to Marburg virus

Samantha E. Zak, J. Dye, K. Chandran, 2017, mAbs.

Massive Mutagenesis®: The Path to Smarter Genetic Libraries

M. Delcourt, O. Dubreuil, P. Thullier, 2013 .

Isolation of antibodies from non-human primates for clinical use.

Jeffrey W. Froude, Thibaut Pelat, P. Thullier, 2014, Current drug discovery technologies.

Isolation and Characterisation of a Human-Like Antibody Fragment (scFv) That Inactivates VEEV In Vitro and In Vivo

S. Dübel, T. Schirrmann, M. Hust, 2012, PloS one.

M. Drouet, J. Mayol, P. Thullier, 2004, Blood.