O. Brekke

发表

Human IgG3 can adopt the disulfide bond pattern characteristic for IgG1 without resembling it in complement mediated cell lysis.

I. Sandlie, T. Michaelsen, A. Aase, 1993, Molecular immunology.

The extended hinge region of IgG3 is not required for high phagocytic capacity mediated by Fcγ receptors, but the heavy chains must be disulfide bonded

I. Sandlie, T. Michaelsen, A. Aase, 1993, European journal of immunology.

Comparisons of the ability of human IgG3 hinge mutants, IgM, IgE, and IgA2, to form small immune complexes: a role for flexibility and geometry.

K. Roux, I. Sandlie, T. Michaelsen, 1998, Journal of immunology.

New technologies in therapeutic antibody development.

G. Løset, O. Brekke, Ole Henrik Brekke, 2003, Current opinion in pharmacology.

Characterization of an FcγRI-binding peptide selected by phage display

J. Andersen, I. Sandlie, T. Michaelsen, 2006 .

Direct isolation of recombinant human antibodies against group B Neisseria meningitidis from scFv expression libraries.

Silje H. Nordgard, T. Michaelsen, O. Brekke, 2003, Journal of immunological methods.

Covalent antibody display—an in vitro antibody-DNA library selection system

J. E. Stacy, K. Fitzgerald, G. Løset, 2005, Nucleic acids research.

A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells

I. Sandlie, T. Michaelsen, T. Gregers, 2006, European journal of immunology.

Tailoring Natural Effector Functions

O. Brekke, J. Thommesen, John E. Thommesen, 2003 .

Activation of complement by an IgG molecule without a genetic hinge

I. Sandlie, T. Michaelsen, O. Brekke, 1993, Nature.

The structural requirements for complement activation by IgG: does it hinge on the hinge?

I. Sandlie, T. Michaelsen, O. Brekke, 1995, Immunology today.

Human IgG isotype‐specific amino acid residues affecting complement‐mediated cell lysis and phagocytosis

I. Sandlie, T. Michaelsen, A. Aase, 1994, European journal of immunology.

Chimeric mouse human IgG3 antibodies with an IgG4‐like hinge region induce complement‐mediated lysis more efficiently than IgG3 with normal hing

I. Sandlie, T. Michaelsen, A. Aase, 1991, European journal of immunology.

Therapeutic antibodies for human diseases at the dawn of the twenty-first century

Inger Sandlie, I. Sandlie, O. Brekke, 2003, Nature Reviews Drug Discovery.

CORRECTION: Therapeutic antibodies for human disease at the dawn of the twenty-first century

I. Sandlie, O. Brekke, 2003, Nature Reviews Drug Discovery.

Troybodies and pepbodies.

L. Sollid, I. Sandlie, T. Michaelsen, 2001, Biochemical Society transactions.

Identification of scFv antibody fragments that specifically recognise the heroin metabolite 6-monoacetylmorphine but not morphine.

M. Braunagel, O. Brekke, J. Stacy, 2003, Journal of immunological methods.

Flexibility and Geometry Small Immune Complexes: A Role for Hinge Mutants, IgM, IgE, and IgA2, to Form Comparisons of the Ability of Human IgG3

K. Roux, I. Sandlie, T. Michaelsen, 1998 .

Functional phage display of two murine α/β T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance

I. Sandlie, G. Løset, B. Bogen, 2007 .

Lysine 322 in the human IgG3 C(H)2 domain is crucial for antibody dependent complement activation.

I. Sandlie, G. Løset, T. Michaelsen, 2000, Molecular immunology.

Identification of prostate cancer antigens by automated high-throughput filter immunoscreening.

S. Funderud, A. Fosså, G. Gaudernack, 2008, Journal of immunological methods.

Tailoring natural effector functions. Antibody engineering beyond humanization.

O. Brekke, J. Thommesen, 2003, Methods in molecular biology.

Dissociating types of mental computation

F. Krause, K. Clausen, V. Bic, 1997 .

Construction, evaluation and refinement of a large human antibody phage library based on the IgD and IgM variable gene repertoire.

J. E. Stacy, G. Løset, O. Brekke, 2005, Journal of immunological methods.

Functional phage display of two murine alpha/beta T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance.

I. Sandlie, G. Løset, B. Bogen, 2007, Protein engineering, design & selection : PEDS.

Neutralizing human antibodies to varicella-zoster virus (VZV) derived from a VZV patient recombinant antibody library.

T E Michaelsen, T. Michaelsen, O. Brekke, 2004, The Journal of general virology.

Activation of complement by an IgG molecule without a genetic hinge

I. Sandlie, T. Michaelsen, O. Brekke, 1993, Nature.