P. Rodriguez

P. Rodriguez, A. Ochoa, J. Zabaleta, 2014, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Regulation of T Cell Receptor CD3ζ Chain Expression byl-Arginine*

J. Ochoa, P. Rodriguez, A. Ochoa, 2002, The Journal of Biological Chemistry.

Kδ signaling in CD 4 + T cell subsets enables selective targeting of T regulatory cells to enhance cancer immunotherapy

S. Khleif, M. Mkrtichyan, P. Rodriguez, 2016 .

Citrulline Can Preserve Proliferation and Prevent the Loss of CD3 ζ Chain Under Conditions of Low Arginine.

Guoyao Wu, D. Eichler, J. Ochoa, 2004, JPEN. Journal of parenteral and enteral nutrition.

Citrulline can preserve proliferation and prevent the loss of CD3 zeta chain under conditions of low arginine.

Guoyao Wu, D. Eichler, J. Ochoa, 2004, JPEN. Journal of parenteral and enteral nutrition.

Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia

A. Wilk, D. Wyczechowska, P. Rodriguez, 2013, Leukemia.

Kindlin‐3 gives patrolling monocytes a strong grip

J. Conejo-Garcia, P. Rodriguez, 2020, Journal of leukocyte biology.

Tumor-directed dysregulation of erythroid progenitors drives immunosuppressive myeloid cells.

P. Rodriguez, J. Mandula, 2022, Cancer cell.

The Central Role of Arginine Catabolism in T-Cell Dysfunction and Increased Susceptibility to Infection After Physical Injury

Y. Vodovotz, T. Billiar, J. Ochoa, 2014, Annals of surgery.

Cavity macrophages stop anti-tumor T cells.

P. Rodriguez, B. Ruffell, 2021, Cancer cell.

Role of c‐Myb in the survival of pre B‐cell acute lymphoblastic leukemia and leukemogenesis

P. Rodriguez, W. Vedeckis, Purvaba J. Sarvaiya, 2012, American journal of hematology.

Corneal neovascularization: a review of the molecular biology and current therapies

T. Foster, W. Lukiw, James M. Hill, 2013 .

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

Peter J. Murray, Sven Brandau, Paulo C. Rodriguez, 2016, Nature Communications.

Metabolism of L-Arginine by Myeloid-Derived Suppressor Cells in Cancer: Mechanisms of T cell suppression and Therapeutic Perspectives

P. Rodriguez, A. Ochoa, P. Raber, 2012, Immunological investigations.

TCR-Independent Metabolic Reprogramming Precedes Lymphoma-Driven Changes in T-cell Fate

J. Cleveland, H. Lawrence, A. Berglund, 2022, Cancer immunology research.

The antimicrobial agent C31G is effective for therapy for HSV-1 ocular keratitis in the rabbit eye model.

T. Foster, W. Lukiw, D. Malamud, 2013, Antiviral research.

Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies

W. Zou, D. Wyczechowska, A. Al-Khami, 2015, Cancer Immunology Research.

Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives

P. Rodriguez, A. Ochoa, 2008, Immunological reviews.

TLR9 engagement on CD4 T lymphocytes represses gamma-radiation-induced apoptosis through activation of checkpoint kinase response elements.

K. Brown, E. Davila, Liqin Zheng, 2008, Blood.

BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells

D. Marchion, P. Bobrowicz, D. Gabrilovich, 2020, Science.

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

D. Munn, S. Mehrotra, D. Marchion, 2019, Nature Communications.

Energy metabolic pathways control the fate and function of myeloid immune cells

A. Al-Khami, P. Rodriguez, A. Ochoa, 2017, Journal of leukocyte biology.

Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity

A. Al-Khami, P. Rodriguez, A. Ochoa, 2017, Front. Immunol..

Arginase I Production in the Tumor Microenvironment by Mature Myeloid Cells Inhibits T-Cell Receptor Expression and Antigen-Specific T-Cell Responses

J. Brayer, J. Ochoa, S. Antonia, 2004, Cancer Research.

Affinity-matured DLL4 ligands as broad-spectrum modulators of Notch signaling

Carolyn E. Dundes, S. Blacklow, Emily D. Egan, 2022, Nature Chemical Biology.

L-arginine availability regulates T-lymphocyte cell-cycle progression.

D. Quiceno, P. Rodriguez, A. Ochoa, 2007, Blood.

Neglected no more: B cell-mediated anti-tumor immunity.

J. Conejo-Garcia, P. Rodriguez, R. Chaurio, 2022, Seminars in immunology.

Single-Cell Characterization of the Immune Microenvironment of Melanoma Brain and Leptomeningeal Metastases

V. Sondak, N. Tran, K. Smalley, 2021, Clinical Cancer Research.

IgA transcytosis and antigen recognition govern ovarian cancer immunity

Chandler D. Gatenbee, R. Wenham, D. Marchion, 2021, Nature.

CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint

Huidong Shi, D. Munn, Yan Cui, 2020, Nature Communications.

Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells.

Chandler D. Gatenbee, Sandhya Prabhakaran, R. Wenham, 2022, Cancer cell.

Regulation of T cell receptor CD3zeta chain expression by L-arginine.

J. Ochoa, P. Rodriguez, A. Ochoa, 2002, The Journal of biological chemistry.

Soluble Mediators of Immune Suppression in the Tumor Microenvironment

P. Rodriguez, A. Ochoa, 2016 .

Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells

Liqin Zheng, Fokhrul Hossain, L. Del Valle, 2017, Oncoimmunology.

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen‐Presenting Cells in Tumors

Huidong Shi, J. Wolchok, B. Baban, 2018, Immunity.

Myeloid-Derived Suppressor Cells in Cancer: Mechanisms and Therapeutic Perspectives

P. Rodriguez, A. Ochoa, 2012 .

Mechanisms of tumor evasion.

S. Ferrone, P. Rodriguez, A. Ochoa, 2005, Cancer treatment and research.

Immune Defects in T Cells From Cancer Patients

P. Correa, P. Rodriguez, A. Ochoa, 2004 .

Mechanisms of tumor evasion from the immune response.

P. Rodriguez, A. Ochoa, A. Zea, 2003, Cancer chemotherapy and biological response modifiers.

l-Arginine Consumption by Macrophages Modulates the Expression of CD3ζ Chain in T Lymphocytes1

J. Ochoa, D. Quiceno, P. Rodriguez, 2003, The Journal of Immunology.

Notch Signaling: A Pivot Regulator of Adaptive and Innate Immunity

P. Rodriguez, T. Kumai, 2018 .

Trp53 inactivation in the tumor microenvironment promotes tumor progression by expanding the immunosuppressive lymphoid-like stromal network.

Yan Cui, Gang Guo, L. Del Valle, 2013, Cancer research.

The cellular metabolic landscape in the tumor milieu regulates the activity of myeloid infiltrates

A. Al-Khami, P. Rodriguez, Eslam Mohamed, 2018, Cellular & Molecular Immunology.

Inhibition of fatty acid oxidation modulates immunosuppressive functions of myeloid-derived suppressor cells and enhances cancer therapies

L. Del Valle, W. Zou, D. Wyczechowska, 2015, Journal of Immunotherapy for Cancer.

Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas

S. Kaufmann, A. Kühl, P. Murray, 2014, Proceedings of the National Academy of Sciences.

Subpopulations of myeloid‐derived suppressor cells impair T cell responses through independent nitric oxide‐related pathways

A. Wilk, K. Reiss, P. Thevenot, 2014, International journal of cancer.

l-Arginine Deprivation Regulates Cyclin D3 mRNA Stability in Human T Cells by Controlling HuR Expression

D. Wyczechowska, P. Rodriguez, A. Ochoa, 2010, The Journal of Immunology.

Controlling HuR Expression mRNA Stability in Human T Cells by l-Arginine Deprivation Regulates Cyclin D3

D. Wyczechowska, P. Rodriguez, A. Ochoa, 2010 .

T cell dysfunction in cancer: role of myeloid cells and tumor cells regulating amino acid availability and oxidative stress.

P. Rodriguez, A. Ochoa, 2006, Seminars in cancer biology.

Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response.

Alfonso Mora, Luigi Di Costanzo, D. Christianson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Targeting Sphingosine Kinase Induces Apoptosis and Tumor Regression for KSHV-Associated Primary Effusion Lymphoma

L. Del Valle, C. Senkal, B. Ogretmen, 2013, Molecular Cancer Therapeutics.

Cancer Biology and Signal Transduction Targeting Sphingosine Kinase Induces Apoptosis and Tumor Regression for KSHV-Associated Primary Effusion Lymphoma

C. Senkal, B. Ogretmen, Z. Qin, 2013 .

Effects of cigarette smoke extract on primary activated T cells.

A. Naura, D. Wyczechowska, P. Rodriguez, 2013, Cellular immunology.

Genomic and single-cell landscape reveals novel drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma.

K. Tsai, Jianhua Zhang, Xingzhi Song, 2022, Cancer discovery.

Sildenafil Suppresses Inflammation-Driven Colorectal Cancer in Mice

R. Kolhe, Yali Hou, F. Berger, 2017, Cancer Prevention Research.

Canonical NFκB signaling in myeloid cells is required for the glioblastoma growth

A. Arbab, R. Kolhe, B. R. Achyut, 2017, Scientific Reports.

IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

G. Rabinovich, L. Glimcher, A. Kossenkov, 2018, Nature.

Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity

J. Pidala, J. D. Del Valle, C. Hu, 2018, Front. Immunol..

Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses

Y. Huo, Sylvia B. Smith, R. Caldwell, 2018, Cell Death & Disease.

MechanismsRemodeling in Asthma: Therapeutic Implications of

Richard J Martin, J. Whitsett, Ji-hang Ju, 2015 .

l-Arginine depletion blunts antitumor T-cell responses by inducing myeloid-derived suppressor cells.

P. Thevenot, M. Ramírez, D. Wyczechowska, 2015, Cancer research.

Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function.

S. Mehrotra, J. Diehl, D. Pytel, 2022, Cancer research.

Targeted Therapy Given after Anti–PD-1 Leads to Prolonged Responses in Mouse Melanoma Models through Sustained Antitumor Immunity

K. Tsai, U. Rix, B. Czerniecki, 2021, Cancer Immunology Research.

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

Gefeng Zhu, Xavier Alvarez, Leann Myers, 2006, The Journal of experimental medicine.

Tumor-infiltrating regulatory dendritic cells inhibit CD8+ T cell function via L-arginine metabolism.

P. Allen, M. Cella, L. Norian, 2009, Cancer research.

P. Rodriguez, J. Mandula, 2021, Cellular immunology.

Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4+ Th1 Responses and Potential Use as a Cancer Vaccine

B. Czerniecki, K. Smalley, A. Basu, 2021, Cancer Immunology Research.

Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity.

Huidong Shi, D. Munn, T. McGaha, 2021, Immunity.

The cellular metabolic landscape in the tumor milieu regulates the activity of myeloid infiltrates

A. Al-Khami, P. Rodriguez, Eslam Mohamed, 2018, Cellular & Molecular Immunology.

Polyphenol-rich extract induces apoptosis with immunogenic markers in melanoma cells through the ER stress-associated kinase PERK

Yu Cao, T. Sandoval, P. Rodriguez, 2019, Cell Death Discovery.

Arginase , Prostaglandins , andMyeloid-Derived Suppressor Cells in Renal Cell Carcinoma

P. Rodriguez, A. Ochoa, A. Zea, 2007 .

Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells

Fokhrul Hossain, Paulo C. Rodriguez, L. Minter, 2019, Front. Immunol..

MEK inhibition reprograms CD8+ T lymphocytes into memory stem cells with potent antitumor effects

Shannon K. Boi, J. Banchereau, S. Barry, 2020, Nature Immunology.

Innate immune cells in the tumor microenvironment.

Si Cheng, Zemin Zhang, M. Pittet, 2021, Cancer cell.

IgA-dominated humoral immune responses govern patients' outcome in endometrial cancer.

Chandler D. Gatenbee, Sandhya Prabhakaran, T. Curiel, 2021, Cancer research.

PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4+ T cell function

A. Boulares, A. Naura, A. Ramsay, 2015, Journal of Translational Medicine.

Defining the mechanisms of action and resistance to the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain models

K. Smalley, Zhihua Chen, Jiannong Li, 2023, bioRxiv.

Relationships among Inflammatory Biomarkers and Self-Reported Treatment-Related Symptoms in Patients Treated with Chemotherapy for Gynecologic Cancer: A Controlled Comparison

R. Wenham, H. Jim, J. Bower, 2023, Cancers.

Metabolic reprogramming of myeloid-derived suppressor cells (MDSC) in cancer

A. Al-Khami, P. Rodriguez, A. Ochoa, 2016, Oncoimmunology.

Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice.

J. Pinilla-Ibarz, Kebin Liu, L. Showe, 2020, The Journal of clinical investigation.

MINOCYCLINE BLOCKS ASTHMA-ASSOCIATED INFLAMMATION IN PART BY INTERFERING WITH THE T CELL RECEPTOR-NF-B-GATA-3-IL-4 AXIS WITHOUT A PROMINENT EFFECT ON PARP 1

J. Jordán, A. Boulares, Ji-hang Ju, 2012 .

Myeloid-Derived Suppressor Cells in Cancer: Mechanisms and Therapeutic Perspectives

P. Rodriguez, A. Ochoa, 2012 .

Canonical NFκB signaling in myeloid cells is required for the glioblastoma growth

A. Arbab, R. Kolhe, B. R. Achyut, 2017, Scientific Reports.

Corrigendum: Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells

L. Minter, B. Osborne, L. Miele, 2019, Frontiers in Immunology.