A. Anishkin

发表

Water dynamics and dewetting transitions in the small mechanosensitive channel MscS.

Sergei Sukharev, S. Sukharev, Andriy Anishkin, 2004, Biophysical journal.

The “Dashpot” Mechanism of Stretch-dependent Gating in MscS

Sergei Sukharev, Bradley Akitake, S. Sukharev, 2005, The Journal of general physiology.

Adaptive behavior of bacterial mechanosensitive channels is coupled to membrane mechanics

S. Sukharev, V. Belyy, B. Akitake, 2010, The Journal of general physiology.

The tension-transmitting 'clutch' in the mechanosensitive channel MscS

Sergei Sukharev, S. Sukharev, V. Belyy, 2010, Nature Structural &Molecular Biology.

Analyses of gating thermodynamics and effects of deletions in the mechanosensitive channel TREK-1

H. Guy, A. Milac, S. Sukharev, 2011, Channels.

Extraction of Deep Phylogenetic Signal and Improved Resolution of Evolutionary Events within the recA/RAD51 Phylogeny

Hong Ma, Zhenhai Zhang, G. Bhardwaj, 2012, 1206.3340.

Molecular Dynamic Simulations Reveal the Structural Determinants of Fatty Acid Binding to Oxy-Myoglobin

G. Bhardwaj, S. Adams, D. V. van Rossum, 2015, PloS one.

Characterization of the resting MscS: modeling and analysis of the closed bacterial mechanosensitive channel of small conductance.

S. Sukharev, B. Akitake, A. Anishkin, 2008, Biophysical journal.

Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate

T. Jegla, D. V. van Rossum, S. Chintapalli, 2015, The Journal of general physiology.

Protein architecture and core residues in unwound α-helices provide insights to the transport function of plant AtCHX17.

K. Venema, H. Sze, A. Anishkin, 2016, Biochimica et biophysica acta.

Gating of the large mechanosensitive channel in situ: estimation of the spatial scale of the transition from channel population responses.

S. Sukharev, A. Anishkin, C. Chiang, 2004, Biophysical journal.

The voltage-dependence of MscL has dipolar and dielectric contributions and is governed by local intramembrane electric field

D. Leo, J. Najem, S. Sukharev, 2018, Scientific Reports.

Channel disassembled: Pick, tweak, and soak parts to soften

S. Sukharev, A. Anishkin, 2017, Channels.

Human mutations highlight an intersubunit cation–π bond that stabilizes the closed but not open or inactivated states of TRPV channels

C. Kung, P. Blount, A. Anishkin, 2019, Proceedings of the National Academy of Sciences.

Myoglobin Interaction with Lactate Rapidly Releases Oxygen: Studies on Binding Thermodynamics, Spectroscopy, and Oxygen Kinetics

S. Adams, S. Chintapalli, A. Anishkin, 2022, International journal of molecular sciences.

Transient receptor potential vanilloid 4 (TRPV4) activation by arachidonic acid requires protein kinase A–mediated phosphorylation

Y. Nishijima, Juan Fang, D. Wilcox, 2018, The Journal of Biological Chemistry.

Tension-activated channels in the mechanism of osmotic fitness in Pseudomonas aeruginosa

S. Sukharev, A. Anishkin, I. Rowe, 2017, The Journal of general physiology.

JGP_201611699 595..610

S. Sukharev, A. Anishkin, I. Rowe, 2017 .

Computational insights on molecular interactions of acifran with GPR109A and GPR109B

S. Chintapalli, A. Anishkin, Kiran Kumar Adepu, 2022, Journal of Molecular Modeling.

Exploring the entry route of palmitic acid and palmitoylcarnitine into myoglobin

S. Adams, S. Chintapalli, A. Anishkin, 2018, Archives of biochemistry and biophysics.

Myoglobin–Pyruvate Interactions: Binding Thermodynamics, Structure–Function Relationships, and Impact on Oxygen Release Kinetics

S. Adams, S. Chintapalli, A. Anishkin, 2022, International journal of molecular sciences.

Mechanosensitive channels: what can we learn from ‘simple’ model systems?

Sergei Sukharev, S. Sukharev, Andriy Anishkin, 2004, Trends in Neurosciences.

Searching for the molecular arrangement of transmembrane ceramide channels.

S. Sukharev, M. Colombini, M Colombini, 2006, Biophysical journal.

The S6 gate in regulatory Kv6 subunits restricts heteromeric K+ channel stoichiometry

T. Jegla, D. V. van Rossum, Aditya Pisupati, 2018, The Journal of general physiology.

L596–W733 bond between the start of the S4–S5 linker and the TRP box stabilizes the closed state of TRPV4 channel

C. Kung, S. Loukin, A. Anishkin, 2015, Proceedings of the National Academy of Sciences.

Catalytic Role of the Substrate Defines Specificity of Therapeutic l-Asparaginase.

J. Weinstein, D. Rogers, Preeti Purwaha, 2015, Journal of molecular biology.

Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia

J. Weinstein, M. Konopleva, T. Link, 2019, Molecular Cancer Therapeutics.

High-Affinity Interactions of Beryllium(2+) with Phosphatidylserine Result in a Cross-Linking Effect Reducing Surface Recognition of the Lipid.

S. Sukharev, A. Dunina-Barkovskaya, Y. Ermakov, 2017, Biochemistry.

The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements

C. Kung, S. Loukin, A. Anishkin, 2014, Pflügers Archiv - European Journal of Physiology.

Stiffened lipid platforms at molecular force foci

C. Kung, A. Anishkin, 2013, Proceedings of the National Academy of Sciences.

Major diversification of voltage-gated K+ channels occurred in ancestral parahoxozoans

M. Martindale, T. Jegla, M. Medina, 2015, Proceedings of the National Academy of Sciences.

On the Conformation of the COOH-terminal Domain of the Large Mechanosensitive Channel MscL

H. Guy, S. Sukharev, A. Anishkin, 2003, The Journal of general physiology.

Crystal Structure of the Labile Complex of IL-24 with the Extracellular Domains of IL-22R1 and IL-20R2

S. Smirnov, A. Wlodawer, J. Lubkowski, 2018, The Journal of Immunology.

Feeling the hidden mechanical forces in lipid bilayer is an original sense

C. Kung, S. Loukin, Jinfeng Teng, 2014, Proceedings of the National Academy of Sciences.

The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells.

J. Weinstein, D. Rogers, Preeti Purwaha, 2013, Blood.

Structural models of TREK channels and their gating mechanism

Carson C. Chow, H. Guy, A. Milac, 2011, Channels.

Salient Frame Detection for Molecular Dynamics Simulations

Dianne P. O'Leary, Robert Patro, Youngmin Kim, 2011, Scientific Visualization: Interactions, Features, Metaphors.

Reevaluation of the evolutionary events within recA/RAD51 phylogeny

Hong Ma, Zhenhai Zhang, G. Bhardwaj, 2013, BMC Genomics.

Mechanical Activation of MscL Revealed by a Locally Distributed Tension Molecular Dynamics Approach

S. Sukharev, J. Vanegas, A. Anishkin, 2020, bioRxiv.

Hydration properties of mechanosensitive channel pores define the energetics of gating

S. Sukharev, B. Akitake, K. Kamaraju, 2010, Journal of physics. Condensed matter : an Institute of Physics journal.

TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour

P. Parekh, V. Tsvilovskyy, D. V. van Rossum, 2014, Nature Communications.

Structural and Energetic Insights Into the Interaction of Niacin With the GPR109A Receptor

S. Chintapalli, A. Anishkin, Kiran Kumar Adepu, 2021, Bioinformatics and biology insights.

Early-Life Socioeconomic Status and the Prevalence of Breast Cancer in Later Life

A. Anishkin, Tetyana Pudrovska, Yifang Shen, 2012, Research on aging.

activity against ASNS-negative cells The glutaminase activity of l-asparaginase is not required for anticancer

J. Weinstein, D. Rogers, Preeti Purwaha, 2014 .

The mechanism of catalysis by L-asparaginase.

J. Weinstein, A. Wlodawer, D. Fushman, 2020, Biochemistry.

Gain-of-function Mutations Reveal Expanded Intermediate States and a Sequential Action of Two Gates in MscL

S. Sukharev, A. Anishkin, C. Chiang, 2005, The Journal of general physiology.

MscS inactivation and recovery are slow voltage-dependent processes sensitive to interactions with lipids

S. Sukharev, A. Anishkin, Joseph Maramba, 2023, bioRxiv.

Novel Molecular Interactions of Acylcarnitines and Fatty Acids with Myoglobin*

S. Adams, P. Mallipeddi, D. V. van Rossum, 2016, The Journal of Biological Chemistry.

A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi

S. Sukharev, A. Anishkin, N. Lander, 2021, eLife.

A bacterial-like mechanosensitive channel controls osmoregulation and infectivity in Trypanosoma cruzi

S. Sukharev, A. Anishkin, N. Lander, 2018, bioRxiv.

Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy

S. Chintapalli, A. Anishkin, Kiran Kumar Adepu, 2022, International journal of molecular sciences.

Tight hydrophobic core and flexible helices yield MscL with a high tension gating threshold and a membrane area mechanical strain buffer

Arjun Sharma, S. Sukharev, J. Vanegas, 2023, bioRxiv.

Mechanosensitive Channels: History, Diversity, and Mechanisms

S. Sukharev, A. Anishkin, S. Sukharev, 2022, Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology.

The voltage-dependence of MscL has dipolar and dielectric contributions and is governed by local intramembrane electric field

D. Leo, J. Najem, S. Sukharev, 2018, Scientific Reports.

Handbook of Ion Channels

S. Sukharev, A. Anishkin, 2023 .

Beta‐barrel models of soluble amyloid beta oligomers and annular protofibrils

H. Guy, S. Durell, Y. Shafrir, 2010, Proteins.

Ceramide channels: destabilization by Bcl-xL and role in apoptosis.

M. Colombini, Leah J. Siskind, L. Beverly, 2015, Biochimica et biophysica acta.

Yeast screens show aromatic residues at the end of the sixth helix anchor transient receptor potential channel gate

C. Kung, W. Haynes, Y. Saimi, 2007, Proceedings of the National Academy of Sciences.

Early-Life Socioeconomic Status and Physical Activity in Later Life

A. Anishkin, Tetyana Pudrovska, 2013, Journal of aging and health.

Straightening and sequential buckling of the pore-lining helices define the gating cycle of MscS

Sergei Sukharev, Bradley Akitake, S. Sukharev, 2007, Nature Structural &Molecular Biology.

Microbial mechanosensation

C. Kung, A. Anishkin, 2005, Current Opinion in Neurobiology.

Adaptive MscS gating in the osmotic permeability response in E. coli: the question of time.

S. Sukharev, A. Anishkin, Miriam Boer, 2011, Biochemistry.

Clarifying the Positive Association Between Education and Prostate Cancer

A. Anishkin, Tetyana Pudrovska, 2015, Journal of applied gerontology : the official journal of the Southern Gerontological Society.

Yeast gain-of-function mutations reveal structure–function relationships conserved among different subfamilies of transient receptor potential channels

C. Kung, W. Haynes, Y. Saimi, 2007, Proceedings of the National Academy of Sciences.

2,2,2-Trifluoroethanol changes the transition kinetics and subunit interactions in the small bacterial mechanosensitive channel MscS.

J. Killian, B. de Kruijff, S. Sukharev, 2007, Biophysical journal.

Personal Mastery and the Medical, Financial, and Physical Cancer Burden: Gender and Race Differences Among Older Adults

A. Anishkin, Tetyana Pudrovska, 2020, Journal of aging and health.

The Bacterial Mechanosensitive Channel MscS: Emerging Principles of Gating and Modulation

S. Sukharev, A. Anishkin, Bradley Akitake, 2007 .

Mechanosensitive channel MscS is critical for termination of the bacterial hypoosmotic permeability response

S. Sukharev, A. Anishkin, Anthony Schams, 2023, The Journal of general physiology.

Mechanosensitive channel MscS is critical for termination of the bacterial hypoosmotic permeability response

S. Sukharev, A. Anishkin, Anthony Schams, 2023, bioRxiv.

MSCS is a Critical Component for Osmotic Survival of Vibrio Cholerae

S. Sukharev, Blake Ushijima, A. Anishkin, 2020, Biophysical Journal.

The cytoplasmic cage domain of the mechanosensitive channel MscS is a sensor of macromolecular crowding

S. Sukharev, K. Kamaraju, A. Anishkin, 2014, The Journal of general physiology.

The pathway and spatial scale for MscS inactivation

S. Sukharev, V. Belyy, K. Kamaraju, 2011, The Journal of general physiology.

Mechanosensitive Channel MscS in the Open State: Modeling of the Transition, Explicit Simulations, and Experimental Measurements of Conductance

Sergei Sukharev, S. Sukharev, Andriy Anishkin, 2008, The Journal of general physiology.

State-stabilizing Interactions in Bacterial Mechanosensitive Channel Gating and Adaptation*

Sergei Sukharev, S. Sukharev, Andriy Anishkin, 2009, The Journal of Biological Chemistry.

Partitioning of Seven Different Classes of Antibiotics into LPS Monolayers Supports Three Different Permeation Mechanisms through the Outer Bacterial Membrane.

Alison J. Scott, S. Rempe, S. Sukharev, 2021, Langmuir.

The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements

C. Kung, S. Loukin, Jinfeng Teng, 2014, Pflügers Archiv - European Journal of Physiology.

Protein architecture and core residues in unwound α-helices provide insights to the transport function of plant AtCHX17.

K. Venema, H. Sze, A. Anishkin, 2016, Biochimica et Biophysica Acta.

Major diversification of voltage-gated K+ channels occurred in ancestral parahoxozoans

M. Martindale, T. Jegla, M. Medina, 2015, Proceedings of the National Academy of Sciences.

High-Affinity Interactions of Beryllium(2+) with Phosphatidylserine Result in a Cross-Linking Effect Reducing Surface Recognition of the Lipid.

S. Sukharev, A. Dunina-Barkovskaya, Y. Ermakov, 2017, Biochemistry.

The core domain as the force sensor of the yeast mechanosensitive TRP channel

C. Kung, Y. Saimi, A. Anishkin, 2011, The Journal of general physiology.

The dynamic hypoosmotic response of Vibrio cholerae relies on the mechanosensitive channel MscS

S. Sukharev, A. Anishkin, Joseph Maramba, 2023, bioRxiv.

Symmetry‐restrained molecular dynamics simulations improve homology models of potassium channels

H. Guy, A. Milac, Andriy Anishkin, 2010, Proteins.

MscL, a Bacterial Mechanosensitive Channel

H. Guy, S. Sukharev, A. Anishkin, 2005 .

Computational Analysis Reveals Unique Binding Patterns of Oxygenated and Deoxygenated Myoglobin to the Outer Mitochondrial Membrane

S. Chintapalli, A. Anishkin, Dipendra Bhandari, 2023, Biomolecules.

Unraveling Protein-Metabolite Interactions in Precision Nutrition: A Case Study of Blueberry-Derived Metabolites Using Advanced Computational Methods

S. Chintapalli, A. Anishkin, Dipendra Bhandari, 2024, Metabolites.

A competing hydrophobic tug on L596 to the membrane core unlatches S4–S5 linker elbow from TRP helix and allows TRPV4 channel to open

C. Kung, S. Loukin, A. Anishkin, 2016, Proceedings of the National Academy of Sciences.

MATHEMATICAL SIMULATION OF ENERGY COUPLING IN MITOCHONDRIA WITHIN THE FRAMEWORK OF THE PROTON-CHEMICAL HYPOTHESIS

A. Anishkin, V. Lemeshko, 1998 .