D. Dunican

发表

Senescent cells harbour features of the cancer epigenome

Peter D. Adams, Nathan D. VanderKraats, Richard R. Meehan, 2013, Nature Cell Biology.

Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes

Wendy A Bickmore, Judith Reichmann, Colm E. Nestor, 2013, Genome Biology.

Genetic diversity within the R408W phenylketonuria mutation lineages in Europe

P. Guldberg, G. Bertorelle, F. Calì, 2003, Human mutation.

Bivalent promoter hypermethylation in cancer is linked to the H327me3/H3K4me3 ratio in embryonic stem cells

Ilya M. Flyamer, W. Bickmore, R. Meehan, 2020, BMC Biology.

Gene expression differences between the microsatellite instability (MIN) and chromosomal instability (CIN) phenotypes in colorectal cancer revealed by high-density cDNA array hybridization

A. Parle‐McDermott, D. Dunican, O. Tighe, 2002, Oncogene.

Kaiso is a genome-wide repressor of transcription that is essential for amphibian development

R. Meehan, A. Ruzov, E. Prokhortchouk, 2004, Development.

The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development

Monika J. Madej, R. Meehan, J. Reddington, 2009, Development.

Gene expression differences between the microsatellite instability (MIN) and chromosomal instability (CIN) phenotypes in colorectal cancer revealed by high-density cDNA array hybridization

A. Parle‐McDermott, D. Dunican, O. Tighe, 2002, Oncogene.

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes.

Colm E. Nestor, J. Dixon, R. Meehan, 2012, Genome research.

Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline

James H. Crichton, R. Meehan, I. Adams, 2013, Cellular and Molecular Life Sciences.

The CXXC-TET bridge — mind the methylation gap!

R. Meehan, S. Pennings, D. Dunican, 2013, Cell Research.

Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems

Mikael Benson, Colm E. Nestor, M. Benson, 2015, Genome Biology.

Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline

Colm E. Nestor, M. Surani, W. Reik, 2012, Development.

Lsh Is Essential for Maintaining Global DNA Methylation Levels in Amphibia and Fish and Interacts Directly with Dnmt1

R. Meehan, S. Pennings, D. Dunican, 2015, BioMed research international.

SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome

Ryan L. Collins, D. MacArthur, Daisuke Sato, 2017, Nature Genetics.

content of human genes Tissue type is a major modifier of the 5-hydroxymethylcytosine Material Supplemental

J. Dixon, R. Meehan, J. Reddington, 2012 .

Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA.

R. Meehan, A. Ruzov, C. Nestor, 2010, BioTechniques.

The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways

Monika J. Madej, R. Meehan, J. Reddington, 2009, Development.

Edinburgh Research Explorer The interaction of xKaiso with xTcf3

Monika J. Madej, R. Meehan, J. Reddington, 2009 .

The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways

Monika J. Madej, R. Meehan, J. Reddington, 2009, Development.

Activation of transcription factor circuity in 2i-induced ground state pluripotency is independent of repressive global epigenetic landscapes

B. Ramsahoye, J. Thomson, R. Meehan, 2020, Nucleic acids research.

Apoptosis and DNA Methylation

Monika J. Madej, R. Meehan, J. Reddington, 2011, Cancers.

Epigenetic silencing in embryogenesis.

R. Meehan, A. Ruzov, S. Pennings, 2005, Experimental cell research.

Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer

Richard R. Meehan, R. Meehan, D. Sproul, 2013, Nucleic acids research.

Lsh regulates LTR retrotransposon repression independently of Dnmt3b function

R. Arceci, C. Semple, J. Greally, 2013, Genome Biology.

xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function

R. Meehan, A. Ruzov, Jamie A. Hackett, 2008, Development.

MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos

H. Leonhardt, R. Meehan, B. Shorning, 2009, Development.

MBD 4 and MLH 1 are required for apoptotic induction in xDNMT 1-depleted embryos

H. Leonhardt, R. Meehan, B. Shorning, 2009 .

Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques

Colm E. Nestor, J. Thomson, Jennifer M. Hunter, 2013, Nucleic acids research.

Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines

A. Parle‐McDermott, D. Dunican, O. Tighe, 2000, British Journal of Cancer.

Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems

M. Benson, J. Thomson, R. Meehan, 2015, Genome Biology.

Gene expression profiling of cells and tissues

A. Parle‐McDermott, D. Dunican, D. Croke, 1997 .

Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA.

Colm E. Nestor, R. Meehan, A. Ruzov, 2010, BioTechniques.

Edinburgh Research Explorer Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques

Colm E. Nestor, Jennifer M. Hunter, J. Moggs, 2022 .

Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes

Colm E. Nestor, W. Bickmore, J. Prendergast, 2013, Genome Biology.