P. Vergara

发表

Antifibrotic and fibrolytic properties of celecoxib in liver damage induced by carbon tetrachloride in the rat

V. Tsutsumi, E. Salazar, P. Muriel, 2010, Liver international : official journal of the International Association for the Study of the Liver.

Targeted-simultaneous expression of Gas1 and p53 using a bicistronic adenoviral vector in gliomas

L. Arregui, J. Benitez, J. Segovia, 2007, Cancer Gene Therapy.

Additive effects of the combined expression of soluble forms of GAS1 and PTEN inhibiting glioblastoma growth

J. Segovia, P. Vergara, L. Sánchez-Hernández, 2018, Gene Therapy.

Neural stem cells producing an inducible and soluble form of Gas1 target and inhibit intracranial glioma growth.

J. Segovia, P. Vergara, A. López-Ornelas, 2014, Cytotherapy.

Gas1 inhibits cell proliferation and induces apoptosis of human primary gliomas in the absence of Shh

J. Benitez, J. Segovia, P. Vergara, 2009, International Journal of Developmental Neuroscience.

Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo

B. Mellström, J. Naranjo, J. Segovia, 2004, Neurobiology of Disease.

Varying expression of neurotrophic factors in rat bone marrow stromal cells according to number of culture passages

N. Pavón, J. Segovia, P. Vergara, 2010 .

Lentiviral transfer of an inducible transgene expressing a soluble form of Gas1 causes glioma cell arrest, apoptosis and inhibits tumor growth

J. Segovia, P. Vergara, T. Mejía-Castillo, 2011, Cancer Gene Therapy.

Behavioral improvement in MPTP-treated nonhuman primates in the HALLWAY task after transfer of TH cDNA to host astrocytes.

Pablo Moreno-Briseño, A. Campos-Romo, J. Carrillo-Ruiz, 2012, Acta neurobiologiae experimentalis.

Mouse Central Nervous System

J. Segovia, P. Vergara, Elizabeth Bautista, 2013 .

Gas1 reduces Ret tyrosine 1062 phosphorylation and alters GDNF-mediated intracellular signaling

J. Segovia, P. Vergara, G. Domínguez-Monzón, 2008, International Journal of Developmental Neuroscience.

Astrocyte-specific expression of tyrosine hydroxylase after intracerebral gene transfer induces behavioral recovery in experimental Parkinsonism

M. Brenner, J. Segovia, P. Vergara, 1998, Gene Therapy.

Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF‐β modulation and oxidative stress

V. Tsutsumi, P. Muriel, M. Shibayama, 2008, Fundamental & clinical pharmacology.

Gene therapy in a rodent model of Parkinson's disease using differentiated C6 cells expressing a GFAP-tyrosine hydroxylase transgene.

M. Brenner, J. Segovia, P. Vergara, 1999, Life sciences.

Resveratrol prevents fibrosis, NF‐κB activation and TGF‐β increases induced by chronic CCl4 treatment in rats

V. Tsutsumi, P. Muriel, M. Shibayama, 2008 .

Intracellular increases of cAMP induce opposite effects in glutamic acid decarboxylase (GAD67) and glial fibrillary acidic protein immunoreactivities in C6 cells

J. Segovia, P. Vergara, Enrique Salero-Coca, 1995, Neuroscience Letters.

Coffee prevents CCl4-induced liver cirrhosis in the rat

V. Tsutsumi, P. Muriel, Y. Rivera-Espinoza, 2011, Hepatology international.

Expression of growth arrest specific 1 (Gas1) in the distal tubules and collecting ducts in normal kidney and in the early stages of diabetic nephropathy

Rafael Rodríguez-Muñoz, J. Reyes, Carmen Namorado-Tonix, 2022, Journal of Molecular Histology.

l-Theanine prevents carbon tetrachloride-induced liver fibrosis via inhibition of nuclear factor κB and down-regulation of transforming growth factor β and connective tissue growth factor

V. Tsutsumi, P. Muriel, M. Shibayama, 2015, Human & experimental toxicology.

Methyl palmitate prevents CCl4‐induced liver fibrosis

V. Tsutsumi, P. Muriel, M. Shibayama, 2008, Journal of applied toxicology : JAT.

Differentiation-dependent expression of transgenes in engineered astrocyte cell lines

M. Brenner, J. Segovia, P. Vergara, 1998, Neuroscience Letters.

Cyclosporin-A inhibits inducible nitric oxide synthase activity and expression after spinal cord injury in rats

F. Pérez-Severiano, J. Segovia, P. Vergara, 2004, Neuroscience Letters.

Curcumin protects against acute liver damage in the rat by inhibiting NF-kappaB, proinflammatory cytokines production and oxidative stress.

P. Muriel, M. Shibayama, J. Segovia, 2007, Biochimica et biophysica acta.

Trolox down-regulates transforming growth factor-beta and prevents experimental cirrhosis.

V. Pérez-Alvarez, V. Tsutsumi, P. Muriel, 2008, Basic & clinical pharmacology & toxicology.

Simultaneous Treatment with Soluble Forms of GAS1 and PTEN Reduces Invasiveness and Induces Death of Pancreatic Cancer Cells

J. Segovia, P. Vergara, Rosa O. González, 2020, OncoTargets and therapy.

Transcriptionally mediated gene targeting of gas1 to glioma cells elicits growth arrest and apoptosis

J. Naranjo, J. Segovia, P. Vergara, 2003, Journal of neuroscience research.

Additive effects of the combined expression of soluble forms of GAS1 and PTEN inhibiting glioblastoma growth

J. Segovia, P. Vergara, L. Sánchez-Hernández, 2018, Gene Therapy.

Expression of Gas1 in Mouse Brain: Release and Role in Neuronal Differentiation

R. Aguilar-Roblero, J. Segovia, P. Vergara, 2017, Cellular and Molecular Neurobiology.

Gas1 expression in parietal cells of Bowman’s capsule in experimental diabetic nephropathy

Rafael Rodríguez-Muñoz, J. Reyes, Carmen Namorado-Tonix, 2017, Histochemistry and Cell Biology.

Growth Arrest Specific 1 (GAS1) Is Abundantly Expressed in the Adult Mouse Central Nervous System

R. Aguilar-Roblero, J. Segovia, P. Vergara, 2013, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Primary astrocytes retrovirally transduced with a tyrosine hydroxylase transgene driven by a glial‐specific promoter elicit behavioral recovery in experimental Parkinsonism

J. Segovia, P. Vergara, F. Trejo, 2000, Journal of neuroscience research.

Thyroid hormones are essential to preserve non-proliferative cells of adult neurogenesis of the dentate gyrus

J. Segovia, P. Vergara, J. Pacheco-Rosado, 2016, Molecular and Cellular Neuroscience.

Nitric oxide synthase immunolocalization and expression in the rat hippocampus after sub-acute lead acetate exposure in rats.

C. Ríos, M. Méndez-Armenta, P. Vergara, 2010, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

N-acetylcysteine prevents carbon tetrachloride-induced liver cirrhosis: role of liver transforming growth factor-beta and oxidative stress

V. Tsutsumi, P. Muriel, M. Shibayama, 2009, European journal of gastroenterology & hepatology.

Early socialization and environmental enrichment of lactating piglets affects the caecal microbiota and metabolomic response after weaning

J. Folch, Y. Ramayo-Caldas, M. D’Angelo, 2021, Scientific Reports.

Resveratrol prevents fibrosis, NF-kappaB activation and TGF-beta increases induced by chronic CCl4 treatment in rats.

V. Tsutsumi, P. Muriel, M. Shibayama, 2008, Journal of applied toxicology : JAT.

Hypothyroidism induces selective oxidative stress in amygdala and hippocampus of rat

C. Ríos, F. Pérez-Severiano, J. Segovia, 2008, Metabolic Brain Disease.

Cyclosporin-A Inhibits Constitutive Nitric Oxide Synthase Activity and Neuronal and Endothelial Nitric Oxide Synthase Expressions after Spinal Cord Injury in Rats

C. Ríos, F. Pérez-Severiano, J. Segovia, 2005, Neurochemical Research.

Involvement of R‐type Ca2+ channels in neurotransmitter release from spinal dorsolateral funiculus terminals synapsing motoneurons

R. Felix, J. Segovia, P. Vergara, 2009, The Journal of comparative neurology.

Age-dependent changes in nitric oxide synthase activity and protein expression in striata of mice transgenic for the Huntington’s disease mutation

B. Escalante, C. Ríos, F. Pérez-Severiano, 2002, Brain Research.

Iron-induced oxidative stress activates AKT and ERK1/2 and decreases Dyrk1B and PRMT1 in neuroblastoma SH-SY5Y cells.

Elizabeth Bautista, J. Segovia, P. Vergara, 2016, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Adenoviral Astrocyte-Specific Expression of BDNF in the Striata of Mice Transgenic for Huntington’s Disease Delays the Onset of the Motor Phenotype

L. Arregui, J. Benitez, J. Segovia, 2011, Cellular and Molecular Neurobiology.

Effects of curcumin on brain-derived neurotrophic factor levels and oxidative damage in obesity and diabetes.

J. Segovia, P. Vergara, S. López-Briones, 2014, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

Nitric Oxide Production in Striatum and Pallidum of Cirrhotic Rats

C. Ríos, F. Pérez-Severiano, P. Muriel, 2005, Neurochemical Research.

Characterization of the pattern of expression of Gas1 in the kidney during postnatal development in the rat

Rafael Rodríguez-Muñoz, Carmen Namorado-Tonix, J. Segovia, 2023, PloS one.

Selective protection against oxidative damage in brain of mice with a targeted disruption of the neuronal nitric oxide synthase gene

J. C. Martínez-Lazcano, F. Pérez-Severiano, P. Vergara, 2007, Journal of neuroscience research.