A. Bagrov

发表

Monoclonal antibody against marinobufagenin reverses cardiac fibrosis in rats with chronic renal failure.

S. Haller, J. Shapiro, O. Fedorova, 2012, American journal of hypertension.

Controlling the Movement of Magnetic Iron Oxide Nanoparticles Intended for Targeted Delivery of Cytostatics

O. Demidov, K. Gareev, A. Bagrov, 2021, International journal of nanomedicine.

Model of Chronic Thromboembolic Pulmonary Hypertension in Rats Caused by Repeated Intravenous Administration of Partially Biodegradable Sodium Alginate Microspheres

O. Moiseeva, A. Bagrov, A. A. Karpov, 2021, International journal of molecular sciences.

The Pressure of Aging.

E. Lakatta, Mingyi Wang, M. AlGhatrif, 2017, The Medical clinics of North America.

High salt is a risk factor for cardiovascular and kidney diseases. What is next, fibrosis?

A. Bagrov, 2021, Journal of hypertension.

Endogenous Bufadienolides, Fibrosis and Preeclampsia

C. Adair, A. Bagrov, V. Kashkin, 2019, Cardiology research and practice.

Renal Ischemia Regulates Marinobufagenin Release in Humans

P. Brewster, S. Haller, Jiang Tian, 2010, Hypertension.

Endogenous digitalis: pathophysiologic roles and therapeutic applications

J. Shapiro, A. Bagrov, 2008, Nature Clinical Practice Nephrology.

ANP Differentially Modulates Marinobufagenin-Induced Sodium Pump Inhibition in Kidney and Aorta

E. Lakatta, C. Morrell, O. Fedorova, 2006, Hypertension.

Comparison of Digitalis Sensitivities of Na+/K+-ATPases from Human and Pig Kidneys

O. Fedorova, A. Askari, A. Bagrov, 2017, ACS omega.

Dietary Sodium Restriction Reduces Arterial Stiffness, Vascular TGF-β-Dependent Fibrosis and Marinobufagenin in Young Normotensive Rats

E. Lakatta, O. Juhasz, J. Shapiro, 2018, International journal of molecular sciences.

Endogenous sodium pump inhibitors, diabetes mellitus and preeclampsia Preliminary observations and a hypothesis.

O. Fedorova, A. Bagrov, V. Kashkin, 2007, Pathophysiology : the official journal of the International Society for Pathophysiology.

The cardiotonic steroid hormone marinobufagenin induces renal fibrosis: implication of epithelial-to-mesenchymal transition.

Larisa V. Fedorova, J. Shapiro, O. Fedorova, 2009, American journal of physiology. Renal physiology.

Endogenous sodium pump inhibitors and age-associated increases in salt sensitivity of blood pressure in normotensives.

David E. Anderson, E. Lakatta, D. Longo, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Inhibition in Kidney and Aorta ANP Differentially Modulates Marinobufagenin-Induced Sodium Pump

E. Lakatta, C. Morrell, O. Fedorova, 2006 .

Endogenous Sodium Pump Inhibitors and Blood Pressure Regulation: An Update on Recent Progress

A. Bagrov, P. Doris, 1998, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Involvement of Marinobufagenin in a Rat Model of Human Preeclampsia

J. Puschett, O. Fedorova, A. Bagrov, 2005, American Journal of Nephrology.

Aortic Fibrosis, Induced by High Salt Intake in the Absence of Hypertensive Response, is Reduced by a Monoclonal Antibody to Marinobufagenin.

E. Lakatta, K. Fishbein, O. Juhasz, 2016, American Journal of Hypertension.

Cardiotonic steroids induce vascular fibrosis via pressure-independent mechanism in NaCl-loaded diabetic rats.

E. Lakatta, A. Konradi, O. Fedorova, 2019, Journal of cardiovascular pharmacology.

Cardiotonic Steroids Differentially Affect Intracellular Na+ and [Na+]i/[K+]i-independent Signaling in C7-MDCK Cells*

S. Orlov, P. Hamet, J. Tremblay, 2005, Journal of Biological Chemistry.

Marinobufagenin Stimulates Fibroblast Collagen Production and Causes Fibrosis in Experimental Uremic Cardiomyopathy

Larisa V. Fedorova, J. Shapiro, Zijian Xie, 2007, Hypertension.

Synthesis of an Endogenous Steroidal Na Pump Inhibitor Marinobufagenin, Implicated in Human Cardiovascular Diseases, Is Initiated by CYP27A1 via Bile Acid Pathway

E. Lakatta, O. Juhasz, O. Fedorova, 2015, Circulation. Cardiovascular genetics.

Effect of Cardiotonic Steroid Marinobufagenin on Vascular Remodeling and Cognitive Impairment in Young Dahl-S Rats

E. Lakatta, P. Rapp, O. Juhasz, 2022, International journal of molecular sciences.

Acute salt loading and cardiotonic steroids in resistant hypertension.

E. Lakatta, A. Konradi, O. Fedorova, 2019, Current topics in membranes.

Plasma level of the endogenous sodium pump ligand marinobufagenin is related to the salt-sensitivity in men

E. Lakatta, O. Melander, O. Fedorova, 2015, Journal of hypertension.

Age-associated increase in salt sensitivity is accompanied by a shift in the atrial natriuretic peptide modulation of the effect of marinobufagenin on renal and vascular sodium pump

E. Lakatta, O. Fedorova, A. Bagrov, 2012, Journal of hypertension.

Endogenous cardiotonic steroids and salt-sensitive hypertension.

J. Shapiro, O. Fedorova, A. Bagrov, 2010, Biochimica et biophysica acta.

Endogenous cardiotonic steroids and differential patterns of sodium pump inhibition in NaCl-loaded salt-sensitive and normotensive rats.

O. Fedorova, A. Bagrov, V. Kashkin, 2009, American journal of hypertension.

Cardenolide and bufadienolide ligands of the sodium pump. How they work together in NaCl sensitive hypertension.

O. Fedorova, A. Bagrov, 2005, Frontiers in bioscience : a journal and virtual library.

Brain ouabain stimulates peripheral marinobufagenin via angiotensin II signalling in NaCl-loaded Dahl-S rats

E. Lakatta, M. Talan, O. Fedorova, 2005, Journal of hypertension.

Antibody to marinobufagenin lowers blood pressure in pregnant rats on a high NaCl intake

E. Lakatta, A. Bzhelyansky, O. Fedorova, 2005, Journal of hypertension.

Endogenous Ligand of &agr;1 Sodium Pump, Marinobufagenin, Is a Novel Mediator of Sodium Chloride–Dependent Hypertension

E. Lakatta, M. Talan, O. Fedorova, 2002, Circulation.

Phorbol Diacetate Potentiates Na+-K+ ATPase Inhibition by a Putative Endogenous Ligand, Marinobufagenin

E. Lakatta, O. Fedorova, A. Bagrov, 2002, Hypertension.

Marinobufagenin, an Endogenous α-1 Sodium Pump Ligand, in Hypertensive Dahl Salt-Sensitive Rats

E. Lakatta, O. Fedorova, A. Bagrov, 2001 .

Endogenous Na,K Pump Ligands Are Differentially Regulated During Acute NaCl Loading of Dahl Rats

E. Lakatta, O. Fedorova, A. Bagrov, 2000, Circulation.

Canrenone Restores Vasorelaxation Impaired by Marinobufagenin in Human Preeclampsia

L. A. Romanova, C. Adair, A. Bagrov, 2022, International journal of molecular sciences.

Preeclampsia: Cardiotonic Steroids, Fibrosis, Fli1 and Hint to Carcinogenesis

C. Adair, A. Bagrov, N. Agalakova, 2021, International journal of molecular sciences.

Preeclampsia: Сardiotonic Steroids, Fibrosis and a Hint to Cancerogenesis

C. Adair, A. Bagrov, N. Agalakova, 2020 .

Antibody to Marinobufagenin Reverses Placenta-Induced Fibrosis of Umbilical Arteries in Preeclampsia

E. Lakatta, C. Adair, O. Fedorova, 2018, International journal of molecular sciences.

Endogenous digitalis-like ligands of the sodium pump: possible involvement in mood control and ethanol addiction

E. Zvartau, O. Fedorova, A. Bagrov, 2002, European Neuropsychopharmacology.

Monoclonal antibody to an endogenous bufadienolide, marinobufagenin, reverses preeclampsia-induced Na/K-ATPase inhibition and lowers blood pressure in NaCl-sensitive hypertension

E. Lakatta, D. Longo, A. Bzhelyansky, 2008, Journal of hypertension.

Endogenous digitalis-like ligands and Na/K-ATPase inhibition in experimental diabetes mellitus.

O. Fedorova, A. Bagrov, I. A. Egorova, 2005, Frontiers in bioscience : a journal and virtual library.

Myocardial PKC &bgr;2 and the Sensitivity of Na/K-ATPase to Marinobufagenin Are Reduced by Cicletanine in Dahl Hypertension

E. Lakatta, M. Talan, O. Fedorova, 2003, Hypertension.

Endogenous bufadienolide mediates pressor response to ethanol withdrawal in rats

E. Lakatta, E. Zvartau, O. Fedorova, 2008, European Neuropsychopharmacology.

Antibody against Na/K-ATPase inhibitor lowers blood pressure and increases vascular Fli1 in experimental preeclampsia.

A. Bagrov, M. Vasyutina, M. Galagudza, 2019, American journal of hypertension.

DigiFab Interacts With Endogenous Cardiotonic Steroids and Reverses Preeclampsia-Induced Na/K-ATPase Inhibition

C. Adair, A. Bzhelyansky, O. Fedorova, 2012, Reproductive Sciences.

In preeclampsia endogenous cardiotonic steroids induce vascular fibrosis and impair relaxation of umbilical arteries

J. Shapiro, A. Mikhailov, O. Fedorova, 2011, Journal of hypertension.

Telocinobufagin, a Novel Cardiotonic Steroid, Promotes Renal Fibrosis via Na+/K+-ATPase Profibrotic Signaling Pathways

W. Tang, O. Fedorova, D. Kennedy, 2018, International journal of molecular sciences.

Uremic Cardiomyopathy—An Endogenous Digitalis Intoxication?: Central Role for the Cardiotonic Steroid Marinobufagenin in the Pathogenesis of Experimental Uremic Cardiomyopathy. Hypertension 47: 488–495, 2006

E. Lakatta, M. Kanj, Larisa V. Fedorova, 2006 .

Salt loading induces redistribution of the plasmalemmal Na/K-ATPase in proximal tubule cells.

J. Shapiro, Zijian Xie, O. Fedorova, 2005, Kidney international.

Cardiotonic Steroids Stimulate Glycogen Synthesis in Human Skeletal Muscle Cells via a Src- and ERK1/2-dependent Mechanism*

A. Chibalin, O. Fedorova, A. Bagrov, 2006, Journal of Biological Chemistry.

Inhibition of Na/K ATPase From Rat Aorta by Two Na/K Pump Inhibitors, Ouabain and Marinobufagenin: Evidence of Interaction With Different α-Subunit Isoforms

O. Fedorova, A. Bagrov, 1997 .

Marinobufagenin-induced vascular fibrosis is a likely target for mineralocorticoid antagonists

E. Lakatta, O. Juhasz, A. Konradi, 2015, Journal of hypertension.

Marinobufagenin (MBG) suppression of ethanol-seeking behavior is associated with inhibition of brain cortex Na/K-ATPase in mice

E. Zvartau, O. Fedorova, A. Bagrov, 2002, European Neuropsychopharmacology.

Magnesium sulfate potentiates effect of DigiFab on marinobufagenin-induced Na/K-ATPase inhibition.

O. Fedorova, A. Bagrov, I. Zazerskaya, 2013, American journal of hypertension.

Interaction of Digibind with endogenous cardiotonic steroids from preeclamptic placentae

A. Bzhelyansky, O. Fedorova, A. Bagrov, 2010, Journal of hypertension.

Endogenous Na/K-ATPase inhibitors in patients with preeclampsia.

E. Lakatta, O. Fedorova, A. Bagrov, 2006, Cellular and molecular biology.

Antiarrhythmic effect of antibodies to digoxin in experimental myocardial infarction (the arrhythmogenic action of endogenous digoxinlike factor)

A. Bagrov, N. Rukoyatkina, P. Štolba, 1991, Bulletin of Experimental Biology and Medicine.

ATPase Inhibition DigiFab Interacts With Endogenous Cardiotonic Steroids and Reverses Preeclampsia-Induced-Nov

C. Adair, A. Bzhelyansky, O. Fedorova, 2012 .

Digifab and immunoneutralization of cardiotonic steroids in preeclampsia

C. Adair, O. Fedorova, A. Bagrov, 2011 .

4.8 PLACENTAL NA/K-ATPASE INHIBITOR MARINOBUFAGENIN INDUCES ARTERIAL WALL FIBROSIS IN PREECLAMPSIA

E. Lakatta, A. Bagrov, Wen Wei, 2018 .

4.6: INFLAMMATION AND AORTIC STIFFNESS. A MULTICENTRE LONGITUDINAL STUDY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

E. Lakatta, A. Bagrov, Y. Grigorova, 2022 .

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase.

J. Lingrel, J. Lorenz, Zijian Xie, 2008, American journal of physiology. Heart and circulatory physiology.

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive (cid:1) Na -ATPase

J. Lingrel, J. Lorenz, Zijian Xie, 2009 .

α1-Na/K-ATPase inhibition rescues aberrant dendritic calcium dynamics and memory deficits in the hippocampus of an Angelman syndrome mouse model

D. Chakraborty, H. Kaphzan, A. Bagrov, 2019, Progress in Neurobiology.

Selective ligands for Na+/K+-ATPase α isoforms differentially and cooperatively regulate excitability of pyramidal neurons in distinct brain regions

D. Chakraborty, H. Kaphzan, O. Fedorova, 2017, Neuropharmacology.

Endogenous Cardiotonic Steroids: Physiology, Pharmacology, and Novel Therapeutic Targets

J. Shapiro, O. Fedorova, A. Bagrov, 2009, Pharmacological Reviews.

Pharmacological effect of exogenous histones on muscles

A. Bagrov, T. Sokolova, E. P. Kharchenko, 1987, Bulletin of experimental biology and medicine.

Marinobufagenin induces increases in procollagen expression in a process involving protein kinase C and Fli-1: implications for uremic cardiomyopathy.

D. Watson, Larisa V. Fedorova, J. Shapiro, 2009, American journal of physiology. Renal physiology.

Central Role for the Cardiotonic Steroid Marinobufagenin in the Pathogenesis of Experimental Uremic Cardiomyopathy

Deepak Malhotra, Samer Khouri, Edward G Lakatta, 2006, Hypertension.

Dietary sodium restriction and association with urinary marinobufagenin, blood pressure, and aortic stiffness.

Bradley S. Fleenor, E. Lakatta, M. Chonchol, 2013, Clinical journal of the American Society of Nephrology : CJASN.

Effects of cardiac glycosides on sodium pump expression and function in LLC-PK1 and MDCK cells.

J. Shapiro, Zijian Xie, O. Fedorova, 2002, Kidney international.

Spironolactone Attenuates Experimental Uremic Cardiomyopathy by Antagonizing Marinobufagenin

S. Haller, Jiang Tian, J. Shapiro, 2009, Hypertension.

Marinobufagenin, an endogenous ligand of alpha-1 sodium pump, is a marker of congestive heart failure severity

E. Lakatta, O. Fedorova, A. Bagrov, 2002, Journal of hypertension.

Coordinated shifts in Na/K-ATPase isoforms and their endogenous ligands during cardiac hypertrophy and failure in NaCl-sensitive hypertension

E. Lakatta, M. Talan, O. Fedorova, 2004, Journal of hypertension.

The dietary sodium-blood pressure plot "stiffens".

E. Lakatta, A. Bagrov, 2004, Hypertension.

Endogenous Digitalis in Acute Myocardial Ischemia

O. Fedorova, A. Bagrov, E. Kuznetsova, 1994 .

Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro‐Fibrotic Signaling

C. Drummond, S. Haller, Jiang Tian, 2016, Journal of the American Heart Association.

Large artery stiffness is associated with marinobufagenin in young adults: the African-PREDICT study

A. Schutte, O. Fedorova, Wayne Smith, 2018, Journal of hypertension.

Elevated Plasma Marinobufagenin, An Endogenous Cardiotonic Steroid, Is Associated With Right Ventricular Dysfunction and Nitrative Stress in Heart Failure

W. Tang, Yuping Wu, D. Kennedy, 2015, Circulation. Heart failure.

Partial nephrectomy as a model for uremic cardiomyopathy in the mouse.

Jiang Tian, J. Shapiro, C. Cooper, 2008, American journal of physiology. Renal physiology.

Chronic α1-Na/K-ATPase inhibition reverses the elongation of the axon initial segment of the hippocampal CA1 pyramidal neurons in Angelman syndrome model mice

H. Kaphzan, A. Bagrov, Prudhvi Raj Rayi, 2020, Neuropsychopharmacology.

High salt intake causes adverse fetal programming--vascular effects beyond blood pressure.

P. Schirmacher, E. Ritz, M. Gross-Weissmann, 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Monoclonal Antibody to Marinobufagenin Downregulates TGFβ Profibrotic Signaling in Left Ventricle and Kidney and Reduces Tissue Remodeling in Salt‐Sensitive Hypertension

E. Lakatta, W. Wood, K. Becker, 2019, Journal of the American Heart Association.

Endogenous cardiotonic steroids in chronic renal failure.

S. Haller, J. Shapiro, O. Fedorova, 2011, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Sodium sensitivity in young adults with high resting end‐tidal CO2

A. Bagrov, D. E. Anderson, D. Parsons, 1998, Journal of hypertension.

Effect of green tea extract on cardiac hypertrophy following 5/6 nephrectomy in the rat.

Chi Han, J. Shapiro, Zijian Xie, 2003, Kidney international.

Effects of two putative endogenous digitalis‐like factors, marinobufagenin and ouabain, on the Na+,K+‐pump in human mesenteric arteries

O. Fedorova, A. Bagrov, A. Bagrov, 1998, Journal of hypertension.

Microvascular function in non‐dippers: Potential involvement of the salt sensitivity biomarker, marinobufagenin—The African‐PREDICT study

A. Schutte, O. Fedorova, Wayne Smith, 2019, Journal of clinical hypertension.

Fli1 and Tissue Fibrosis in Various Diseases

A. Bagrov, N. Agalakova, I. V. Romanova, 2023, International journal of molecular sciences.

Mammalian Bufadienolide Is Synthesized From Cholesterol in the Adrenal Cortex by a Pathway That Is Independent of Cholesterol Side-Chain Cleavage

E. Lalli, P. Sassone-Corsi, D. Stocco, 2000, Hypertension.

Endogenous cardiotonic steroids: clinical perspectives

J. Shapiro, O. Fedorova, A. Bagrov, 2008 .

Marinobufagenin enhances cardiac contractility in mice with ouabain‐sensitive α1 Na,K‐ATPase (NKA)

J. Lingrel, J. Lorenz, O. Fedorova, 2008 .

epithelial-to-mesenchymal transition The cardiotonic steroid hormone marinobufagenin induces renal fibrosis: implication of

B. Kahaleh, Larisa V. Fedorova, J. Shapiro, 2009 .

Intrahippocampal microinjection of an exquisitely low dose of ouabain mimics NaCl loading and stimulates a bufadienolide Na/K-ATPase inhibitor

E. Lakatta, M. Talan, O. Fedorova, 2007, Journal of hypertension.

Expression of Pro-Fibrotic Factors in Cardiac Tissue of Wistar and Sprague–Dawley Rats during the Development of Chronic Kidney Disease

A. Bagrov, N. Agalakova, I. V. Romanova, 2023, Journal of Evolutionary Biochemistry and Physiology.

Characterization of a urinary bufodienolide Na+,K+-ATPase inhibitor in patients after acute myocardial infarction.

W. Howald, O. Fedorova, A. Bagrov, 1998, Hypertension.

High end tidal CO2association with blood pressure response to sodium loading in older adults

A. Bagrov, D. Parsons, D. Anderson, 1996, Journal of Hypertension.

Plasma marinobufagenin-like and ouabain-like immunoreactivity in adrenocorticotropin-treated rats.

O. Fedorova, A. Bagrov, D. E. Anderson, 1998, American journal of hypertension.

Marinobufagenin in Urine: A Potential Marker of Predisposition to Ethanol and a Target for Spironolactone.

A. Bagrov, V. Kashkin, E. Shekunova, 2018, Current hypertension reviews.

P.6.a.003 Spironolactone suppresses ethanol-seeking behavior and relapse in rats

A. Bagrov, V. Kashkin, E. Shekunova, 2013, European Neuropsychopharmacology.

Circulating bufodienolide and cardenolide sodium pump inhibitors in preeclampsia.

O. Fedorova, A. Bagrov, R. Dmitrieva, 1999, Journal of hypertension.

Simultaneous measurement of marinobufagenin, ouabain, and hypertension-associated protein in various disease states.

N. Vaziri, H. Gonick, O. Fedorova, 1998, Clinical and experimental hypertension.

Endogenous marinobufagenin-like factor in acute plasma volume expansion.

O. Fedorova, A. Bagrov, A. Y. Bagrov, 1998, Clinical and experimental hypertension.

Plasma marinobufagenin-like and ouabain-like immunoreactivity during saline volume expansion in anesthetized dogs.

O. Fedorova, A. Bagrov, R. Dmitrieva, 1996, Cardiovascular research.

Spironolactone Attenuates Experimental Uremic Cardiomyopathy by Antagonizing Marinobufagenin

S. Haller, Jiang Tian, J. Shapiro, 2009, Hypertension.

Endogenous marinobufagenin-like immunoreactive factor and Na+, K+ ATPase inhibition during voluntary hypoventilation.

O. Fedorova, A. Bagrov, R. Dmitrieva, 1995, Hypertension.