N. Birsa

发表

ALS-FUS mutation affects the activities of HuD/ELAVL4 and FMRP leading to axon phenotypes in motoneurons

V. de Turris, E. Fisher, M. Morlando, 2021 .

Reply: TDP-43 mutations increase HNRNP A1-7B through gain of splicing function.

V. Plagnol, A. Acevedo-Arozena, F. D. Giorgio, 2018 .

TDP-43 mutations increase HNRNP A1-7B through gain of splicing function.

V. Plagnol, A. Acevedo-Arozena, F. De Giorgio, 2018, Brain : a journal of neurology.

Familial hemiplegic migraine CaV2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain

M. Ferrari, E. Fabbretti, A. M. van den Maagdenberg, 2010, Molecular pain.

Peroxisomal fission is modulated by the mitochondrial Rho‐GTPases, Miro1 and Miro2

G. López-Doménech, J. Kittler, N. Birsa, 2020, EMBO reports.

The mitochondrial Rho-GTPase, Miro, is resident at peroxisomes and regulates peroxisomal trafficking and morphology

G. López-Doménech, J. Kittler, N. Birsa, 2017, bioRxiv.

A Comparison of Low Read Depth QuantSeq 3′ Sequencing to Total RNA-Seq in FUS Mutant Mice

V. Plagnol, M. Secrier, P. Fratta, 2020, Frontiers in Genetics.

C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A

L. Partridge, J. Choudhary, Lu Yu, 2019, Acta Neuropathologica.

The C-terminal Src Inhibitory Kinase (Csk)-mediated Tyrosine Phosphorylation Is a Novel Molecular Mechanism to Limit P2X3 Receptor Function in Mouse Sensory Neurons*

P. Carloni, E. Fabbretti, Vanessa Leone, 2009, The Journal of Biological Chemistry.

FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention

Anna L. Brown, I. Bozzoni, V. Plagnol, 2020, Nucleic acids research.

FUS ALS-causative mutations impact FUS autoregulation and the processing of RNA-binding proteins through intron retention

I. Bozzoni, V. Plagnol, O. Mühlemann, 2019, bioRxiv.

Cytoplasmic functions of TDP-43 and FUS and their role in ALS.

P. Fratta, N. Birsa, Matthew Bentham, 2020, Seminars in cell & developmental biology.

Miro proteins coordinate microtubule‐ and actin‐dependent mitochondrial transport and distribution

G. López-Doménech, J. Kittler, D. Ivankovic, 2018, The EMBO journal.

FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation

J. Forman-Kay, P. A. Chong, G. Schiavo, 2020, Science Advances.

Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis

Eric T. Wang, Nicolas L. Fawzi, E. Wang, 2018, The EMBO journal.

Calcium/calmodulin‐dependent serine protein kinase (CASK) is a new intracellular modulator of P2X3 receptors

E. Fabbretti, A. Nistri, N. Birsa, 2013, Journal of neurochemistry.

Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response

R. Bürli, N. Brandon, G. López-Doménech, 2021, The EMBO journal.

Miro ubiquitination is critical for efficient damage-induced PINK1/Parkin-mediated mitophagy

N. Brandon, G. López-Doménech, J. Kittler, 2018, bioRxiv.

Ubiquitination at the mitochondria in neuronal health and disease

J. Kittler, N. Birsa, Christian Covill-Cooke, 2017, Neurochemistry International.

Miro sculpts mitochondrial dynamics in neuronal health and disease

Michael J. Devine, Josef T. Kittler, J. Kittler, 2016, Neurobiology of Disease.

Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase*

David Komander, Josef T. Kittler, K. Bhatia, 2014, The Journal of Biological Chemistry.

V. de Turris, E. Fisher, M. Morlando, 2021, Communications Biology.

DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites

C. Korth, M. Pathania, J. Kittler, 2015, The Journal of Biological Chemistry.

Mitochondrial trafficking in neurons and the role of the Miro family of GTPase proteins.

G. López-Doménech, J. Kittler, N. Birsa, 2013, Biochemical Society transactions.

RNA-binding protein network alteration causes aberrant axon branching and growth phenotypes in FUS ALS mutant motoneurons

E. Fisher, P. Fratta, V. Turris, 2020 .

Travelling Together: A Unifying Pathomechanism for ALS

G. Schiavo, A. Tosolini, P. Fratta, 2019, Trends in Neurosciences.

Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response

J. Harper, J. Paulo, A. Ordureau, 2015, Proceedings of the National Academy of Sciences.