A. M. Santos

发表

CalQuo: automated, simultaneous single-cell and population-level quantification of global intracellular Ca2+ responses

Steven F. Lee, S. Davis, C. Eggeling, 2015, Scientific Reports.

A cell-topography based mechanism for ligand discrimination by the T-cell receptor

D. Klenerman, J. Tzou, Steven F. Lee, 2018 .

Reconstitution of immune cell interactions in free-standing membranes

Michael Loran Dustin, S. Davis, C. Eggeling, 2018, Journal of Cell Science.

Reconstitution of immune cell interactions in free-standing membranes

Michael Loran Dustin, S. Davis, C. Eggeling, 2018, bioRxiv.

A streamlined implementation of the glutamine synthetase-based protein expression system

R. Owens, S. Davis, J. Nettleship, 2013, BMC Biotechnology.

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation

S. Davis, S. Fabre, G. Bismuth, 2011, European journal of immunology.

Capturing resting T cells: the perils of PLL

Christian Eggeling, Aleks Ponjavic, Ana Mafalda Santos, 2018, Nature Immunology.

Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells

C. Eggeling, E. Sezgin, I. Urbančič, 2021, FEBS letters.

Aggregation and immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells

C. Eggeling, E. Sezgin, I. Urbančič, 2020, bioRxiv.

Membrane Ultrastructure and T Cell Activation

S. Davis, Omer Dushek, Johannes Pettmann, 2018, Front. Immunol..

University of Southern Denmark Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation Fritzsche,

E. Betzig, S. Davis, C. Eggeling, 2017 .

The remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions Short title: The remarkably low affinity of CD4 for pMHC II

Paul D. Dunne, D. Klenerman, L. Fugger, 2016 .

The kinase occupancy of T-cell coreceptors reconsidered

S. Fraser, A. M. Santos, Edward Jenkins, 2022, bioRxiv.

Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC

G. Hummer, R. Tampé, Christoph Thomas, 2022, Cell.

The kinase occupancy of T cell coreceptors reconsidered

S. Fraser, A. M. Santos, Edward Jenkins, 2022, bioRxiv.

Single-cell measurements of two-dimensional binding affinity across cell contacts

Peter Jönsson, A. M. Santos, T. Dam, 2021, Biophysical journal.

A Protein Expression Toolkit for Studying Signaling in T Cells.

J. Huo, A. M. Santos, Deborah Hatherley, 2017, Methods in molecular biology.

Coreceptors and TCR Signaling – the Strong and the Weak of It

Michael Loran Dustin, A. M. Santos, Š. Bálint, 2020, Frontiers in Cell and Developmental Biology.

vLUME: 3D virtual reality for single-molecule localization microscopy

Steven F. Lee, A. Ponjavic, Lisa-Maria Needham, 2020, Nature Methods.

Immune Checkpoints as Therapeutic Targets in Autoimmunity

R. Cornall, A. M. Santos, C. Anzilotti, 2018, Front. Immunol..

Dimensions and Interactions of Large T-Cell Surface Proteins

Peter Jönsson, A. M. Santos, Y. Lui, 2018, Front. Immunol..

The Scavenger Receptor SSc5D Physically Interacts with Bacteria through the SRCR-Containing N-Terminal Domain

J. Homola, A. M. Santos, M. Bockova, 2016, Front. Immunol..

resPAINT: Accelerating Volumetric Super‐Resolution Localisation Microscopy by Active Control of Probe Emission

D. Klenerman, Steven F. Lee, A. Ponjavic, 2022, bioRxiv.

Rituximab capping triggers intracellular reorganization of B cells

T. Koller, C. Eggeling, D. Davis, 2017 .

Effects of a local auxiliary protein on the two-dimensional affinity of a TCR–peptide MHC interaction

J. Rossjohn, J. Petersen, Peter Jönsson, 2020, Journal of Cell Science.

A cell topography-based mechanism for ligand discrimination by the T cell receptor

D. Klenerman, J. Tzou, Steven F. Lee, 2019, Proceedings of the National Academy of Sciences.

Constraining CD45 exclusion at close-contacts provides a mechanism for discriminatory T-cell receptor signalling

D. Klenerman, J. Tzou, Steven F. Lee, 2017 .

Detection of Cell Surface Ligands for Human Synovial γδ T Cells

Gavin J. Wright, C. Collins, R. Budd, 2019, The Journal of Immunology.

Antigen discrimination by T cells relies on size-constrained microvillar contact

D. Klenerman, Steven F. Lee, A. M. Santos, 2023, Nature Communications.

Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation

Christian Eggeling, Eric Betzig, Dominic Waithe, 2017, Science Advances.

Soft Polydimethylsiloxane-Supported Lipid Bilayers for Studying T Cell Interactions

D. Klenerman, K. Franze, J. McColl, 2020, Biophysical journal.

Robust T-cell signaling triggered on soft polydimethylsiloxane-supported lipid-bilayers

D. Klenerman, K. Franze, J. McColl, 2020, bioRxiv.

Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions

Paul D. Dunne, D. Klenerman, L. Fugger, 2016, Proceedings of the National Academy of Sciences.

Hydrodynamic trapping measures the interaction between membrane-associated molecules

Mikael Lund, Peter Jönsson, A. M. Santos, 2018, bioRxiv.

Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling

D. Klenerman, A. Ponjavic, Nicole Ashman, 2021, Proceedings of the National Academy of Sciences.

Single-Molecule Light-Sheet Imaging of Suspended T Cells.

D. Klenerman, Steven F. Lee, A. Ponjavic, 2018, Biophysical journal.

Three-Dimensional Super-Resolution in Eukaryotic Cells Using the Double-Helix Point Spread Function

Alexander R Carr, Aleks Ponjavic, Ana Mafalda Santos, 2017, Biophysical journal.

A cell-topography based mechanism for ligand discrimination by the T-cell receptor

D. Klenerman, J. Tzou, Steven F. Lee, 2017, bioRxiv.