P. Dandliker

发表

Charge Transfer through the DNA Base Stack

J. Barton, R. Holmlin, P. Dandliker, 1997 .

Charge Transfer through the DNA Base Stack

J. Barton, R. Holmlin, P. Dandliker, 1997 .

LADUNGSUBERTRAGUNG DURCH DEN DNA-BASENSTAPEL

J. Barton, R. Holmlin, P. Dandliker, 1997 .

Mechanism of Action of a Novel Series of Naphthyridine-Type Ribosome Inhibitors: Enhancement of tRNA Footprinting at the Decoding Site of 16S rRNA

B. Beutel, Yingna Cai, Candace Black-Schaefer, 2005, Antimicrobial Agents and Chemotherapy.

Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space

Peter S. Kutchukian, Patrick J. Curran, Jeannie T. Lee, 2019, SLAS discovery : advancing life sciences R & D.

Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays.

Candace Black-Schaefer, L. Chovan, P. Dandliker, 2004, Rapid communications in mass spectrometry : RCM.

Novel Antibacterial Class

Xiaoan Ruan, N. Soni, Philip J. Merta, 2003, Antimicrobial Agents and Chemotherapy.

Dendritic Porphyrins: Modulating Redox Potentials of Electroactive Chromophores with Pendant Multifunctionality

F. Diederich, C. Knobler, M. Gross, 1994 .

Dendrimers with Porphyrin Cores: Synthetic Models for Globular Heme Proteins

F. Diederich, J. Gisselbrecht, M. Gross, 1997 .

Water‐Soluble Dendritic Iron Porphyrins: Synthetic Models of Globular Heme Proteins

F. Diederich, J. Gisselbrecht, M. Gross, 1996 .

Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase.

Peter S. Kutchukian, M. Glick, M. Altman, 2017, ACS chemical biology.

Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor

Irena Ivanovska, C. Chiu, I. Kariv, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Synthesis and antibacterial activity of 5-methoxy- and 5-hydroxy-6-fluoro-1,8-naphthyridone-3-carboxylic acid derivatives.

Y. Gu, B. Beutel, L. Chovan, 2005, Bioorganic & medicinal chemistry letters.

Solid phase extraction as a faster alternative to HPLC: application to MS analysis of metabolic stability samples.

L. Chovan, P. Dandliker, Y. Lau, 2007, Journal of pharmaceutical sciences.

Thienopyridine urea inhibitors of KDR kinase.

K. Glaser, S. Davidsen, N. Soni, 2007, Bioorganic & medicinal chemistry letters.

Identification of G-Quadruplex-Binding Inhibitors of Myc Expression through Affinity Selection–Mass Spectrometry

Patrick J. Curran, J. O'neil, N. Rizvi, 2018, SLAS discovery : advancing life sciences R & D.

Oxidative charge transfer To repair thymine dimers and damage guanine bases in DNA assemblies containing tethered metallointercalators.

J. Barton, P. Dandliker, M. Núñez, 1998, Biochemistry.

Pharmacokinetic Enhancement of the Hepatitis C Virus Protease Inhibitors VX-950 and SCH 503034 by Co-Dosing with Ritonavir

D. Kempf, J. Randolph, K. Marsh, 2007, Antiviral chemistry & chemotherapy.

Novel inhibitors of bacterial protein synthesis: structure-activity relationships for 1,8-naphthyridine derivatives incorporating position 3 and 4 variants.

N. Soni, R. Clark, Y. Gu, 2004, Bioorganic & medicinal chemistry letters.

Oxidative Thymine Dimer Repair in the DNA Helix

J. Barton, R. Holmlin, J K Barton, 1997, Science.

Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges.

A. Peier, D. Lane, J. Hochman, 2018, Bioorganic & medicinal chemistry.

Definitive Metabolite Identification Coupled with Automated Ligand Identification System (ALIS) Technology: A Novel Approach to Uncover Structure-Activity Relationships and Guide Drug Design in a Factor IXa Inhibitor Program.

Y. Liu, S. Hill, E. Sherer, 2016, Journal of medicinal chemistry.

4 Pharmacokinetic boosting of VX-950, an inhibitor of HCV protease, by co-dosing with ritonavir

D. Kempf, J. Randolph, K. Marsh, 2006 .

Targeting Xist with compounds that disrupt RNA structure and X inactivation

Trushar R. Patel, Jeannie T. Lee, J. Burchard, 2022, Nature.

Exploring new targets and chemical space with affinity selection-mass spectrometry

D. A. Annis, R. Prudent, J. Ortholand, 2020, Nature Reviews Chemistry.

An orally available non-nucleotide STING agonist with antitumor activity

Andrew M Haidle, J. Cumming, I. Kariv, 2020, Science.

Integration of Affinity Selection–Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-κB Pathway

Patrick J. Curran, Sujata Sharma, I. Kariv, 2016, Journal of biomolecular screening.

Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.

Ali Nahvi, Corey Strickland, J. Burchard, 2018, ACS chemical biology.

Nanoscale synthesis and affinity ranking

Christine L. Andrews, Patrick J. Curran, Tim Cernak, 2018, Nature.

A Strategy for Discovery of Novel Broad-Spectrum Antibacterials Using a High-Throughput Streptococcus pneumoniae Transcription/Translation Screen

L. Traphagen, U. Warrior, N. Soni, 2004, Journal of biomolecular screening.

SOS-NMR: a saturation transfer NMR-based method for determining the structures of protein-ligand complexes.

P. Hajduk, E. Olejniczak, J. Mack, 2004, Journal of the American Chemical Society.

Rapid hit to lead evaluation of pyrazolo[3,4-d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists.

J. Brioni, R. Moreland, P. Honore, 2007, Bioorganic & medicinal chemistry letters.

Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges.

A. Peier, D. Lane, J. Hochman, 2018, Bioorganic & Medicinal Chemistry.

Nanoscale synthesis and affinity ranking

Patrick J. Curran, T. Cernak, P. Dandliker, 2018, Nature.

Integration of Affinity Selection–Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-κB Pathway

Patrick J. Curran, Sujata Sharma, I. Kariv, 2016, Journal of biomolecular screening.