J. Levine

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Plasma CXCL9 elevations correlate with chronic GVHD diagnosis.

T. Braun, B. Storer, Stephanie J. Lee, 2014, Blood.

Soluble tumor necrosis factor receptor: enbrel (etanercept) for subacute pulmonary dysfunction following allogeneic stem cell transplantation.

T. Braun, S. Mineishi, E. White, 2012, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

The impact of recent vincristine on human hematopoietic progenitor cell collection in pediatric patients with central nervous system tumors

P. Robertson, J. Levine, R. Davenport, 2014, Transfusion.

Graft-versus-host disease

E. Holler, J. Ferrara, J. Levine, 2009, The Lancet.

First International Workshop on the Biology , Prevention and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation : Report from the Committee on Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation

E. Estey, D. Porter, K. Peggs, 2010 .

NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation.

E. Estey, D. Maloney, D. Porter, 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Current and Emerging Targeted Therapies for Acute Graft-Versus-Host Disease

J. Levine, Stelios Kasikis, A. Etra, 2020, BioDrugs.

Pooled safety analysis of tisagenlecleucel in children and young adults with B cell acute lymphoblastic leukemia

S. Rives, Krysta D Schlis, A. Baruchel, 2021, Journal for ImmunoTherapy of Cancer.

Phase I/II Trial of a Combination of Anti-CD3/CD7 Immunotoxins for Steroid-Refractory Acute Graft-versus-Host Disease.

M. Netea, J. Inthout, R. Masereeuw, 2019, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Therapeutic targets and emerging treatment options in gastrointestinal acute graft-versus-host disease

J. Ferrara, J. Levine, A. Renteria, 2016, Expert opinion on orphan drugs.

Utility of cranial boost in addition to total body irradiation in the treatment of high risk acute lymphoblastic leukemia.

T. Braun, D. Wechsler, L. Pierce, 2004, International journal of radiation oncology, biology, physics.

Treosulfan, Fludarabine, and Low-Dose Total Body Irradiation for Children and Young Adults with Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Allogeneic Hematopoietic Cell Transplantation: Prospective Phase II Trial of the Pediatric Blood and Marrow Transplant Consortium.

J. Chewning, R. Hilger, B. Shaw, 2018, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Comparison of pediatric allogeneic transplant outcomes using myeloablative busulfan with cyclophosphamide or fludarabine.

S. Mineishi, M. Pasquini, R. Gale, 2018, Blood advances.

Influence of Age on Acute and Chronic GVHD in Children Undergoing HLA-Identical Sibling Bone Marrow Transplantation for Acute Leukemia: Implications for Prophylaxis.

M. Aljurf, M. Horowitz, R. Gale, 2018, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Clinical applications for biomarkers of acute and chronic graft-versus-host disease.

S. Paczesny, J. Levine, S. Sarantopoulos, 2012, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Pathogenesis and management of graft-versus-host disease.

S. Choi, J. Ferrara, J. Levine, 2010, Immunology and allergy clinics of North America.

Design and Implementation of the International Genetics and Translational Research in Transplantation Network

Graham M Lord, Jason H. Moore, W. Guan, 2015, Transplantation.

TNF-receptor inhibitor therapy for the treatment of children with idiopathic pneumonia syndrome. A joint Pediatric Blood and Marrow Transplant Consortium and Children's Oncology Group Study (ASCT0521).

S. Grupp, B. Langholz, E. White, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Mycobacterium chelonae necrotizing pneumonia after allogeneic hematopoietic stem cell transplant: report of clinical response to treatment with tigecycline

S. Mineishi, J. Levine, D. Kaul, 2009, Transplant infectious disease : an official journal of the Transplantation Society.

Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation

Robin R. Shields-Cutler, D. Longo, D. Knights, 2020, Science Translational Medicine.

Tisagenlecleucel immunogenicity in relapsed/refractory acute lymphoblastic leukemia and diffuse large B-cell lymphoma

U. Jaeger, S. Grupp, C. Tam, 2021, Blood advances.

A refined risk score for acute GVHD that predicts response to initial therapy, survival and transplant-related mortality

M. Robin, M. Pasquini, Richard J. Jones, 2015 .

Tisagenlecleucel Model‐Based Cellular Kinetic Analysis of Chimeric Antigen Receptor–T Cells

S. Grupp, B. Levine, C. June, 2019, CPT: pharmacometrics & systems pharmacology.

Donor leukocyte infusions in acute lymphocytic leukemia

R. Collins, A. Kirk, D. Porter, 2000, Bone Marrow Transplantation.

The impact of soluble tumor necrosis factor receptor etanercept on the treatment of idiopathic pneumonia syndrome after allogeneic hematopoietic stem cell transplantation.

T. Braun, E. White, G. Yanik, 2008, Blood.

Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia

S. Grupp, B. Levine, C. June, 2018, Clinical Cancer Research.

Outcomes after auto-SCT in African Americans with multiple myeloma

S. Mineishi, J. Levine, P. Reddy, 2009, Bone Marrow Transplantation.

Pilot study of iodine-131-metaiodobenzylguanidine in combination with myeloablative chemotherapy and autologous stem-cell support for the treatment of neuroblastoma.

K. Matthay, G. Yanik, R. Hutchinson, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

BMT CTN State of the Science Symposium 2021: Looking Forward as the Network Celebrates its 20th Year.

E. Leifer, P. Hari, H. Heslop, 2021, Transplantation and cellular therapy.

Phase 1/2 trial of vorinostat plus tacrolimus and mycophenolate to prevent graft versus host disease following related donor reduced intensity conditioning allogeneic hematopoietic stem cell transplantation

J. Dipersio, C. Dinarello, Thomas Braun, 2014 .

Biomarkers in acute graft-versus-host disease: new insights

J. Ferrara, J. Levine, Hrishikesh K. Srinagesh, 2019, Therapeutic advances in hematology.

Acute graft-versus-host disease biomarkers measured during therapy can predict treatment outcomes: a Blood and Marrow Transplant Clinical Trials Network study.

J. Bolaños-Meade, Juan Wu, S. Paczesny, 2012, Blood.

Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression.

T. Braun, J. Geiger, A. Chang, 2001, Cancer research.

Low-dose cidofovir treatment of BK virus-associated hemorrhagic cystitis in recipients of hematopoietic stem cell transplant

S. Mineishi, D. Newton, J. Levine, 2007, Bone Marrow Transplantation.

Monitoring Neurocognitive Functioning After Pediatric Cellular Therapy or Hematopoietic Cell Transplant: Guidelines From the COG Neurocognition in Cellular Therapies Task Force

J. Chewning, S. Braniecki, W. Pelletier, 2022, Transplantation and cellular therapy.

Low Paneth cell numbers at onset of gastrointestinal graft-versus-host disease identify patients at high risk for nonrelapse mortality.

T. Braun, J. Greenson, E. Holler, 2013, Blood.

Advances in predicting acute GVHD

J. Ferrara, J. Levine, Andrew C. Harris, 2013, British journal of haematology.

National Institutes of Health State of the Science Symposium in Therapeutic Apheresis: scientific opportunities in extracorporeal photopheresis.

S. Sloan, D. Couriel, N. Dunbar, 2015, Transfusion medicine reviews.

Graft-versus-host disease and graft-versus-leukemia after donor leukocyte infusion.

D. Porter, J. Levine, 2006, Seminars in hematology.

Donor leukocyte infusions for multiple myeloma

R. Collins, A. Kirk, D. Porter, 2000, Bone Marrow Transplantation.

National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IIb. The 2020 Preemptive Therapy Working Group Report.

G. Cuvelier, J. Pidala, H. Greinix, 2021, Transplantation and cellular therapy.

Pilot trial on the use of etanercept and methylprednisolone as primary treatment for acute graft-versus-host disease.

T. Braun, M. Becker, G. Yanik, 2005, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Cardiac complications in patients undergoing a reduced-intensity conditioning hematopoietic stem cell transplantation

T. Braun, S. Mineishi, J. Levine, 2010, Bone Marrow Transplantation.

Prospective trial of chemotherapy and donor leukocyte infusions for relapse of advanced myeloid malignancies after allogeneic stem-cell transplantation.

T. Braun, R. Collins, K. Cornetta, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

hematopoietic stem cell transplantation treatment of idiopathic pneumonia syndrome after allogeneic The impact of soluble tumor necrosis factor receptor etanercept on the

T. Braun, E. White, G. Yanik, 2011 .

Plasma elevations of tumor necrosis factor-receptor-1 at day 7 postallogeneic transplant correlate with graft-versus-host disease severity and overall survival in pediatric patients.

T. Braun, S. Choi, S. Paczesny, 2008, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Extracorporeal photopheresis in prevention and treatment of acute GVHD.

C. Kitko, J. Levine, 2015, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.

Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth.

Nallasivam Palanisamy, Arul M Chinnaiyan, James A Connelly, 2015, JAMA.

ST2 as a marker for risk of therapy-resistant graft-versus-host disease and death.

T. Braun, S. Hanash, J. Ritz, 2013, The New England journal of medicine.

A Pilot Study of Addition of Amifostine to Melphalan, Carboplatin, Etoposide, and Cyclophosphamide With Autologous Hematopoietic Stem Cell Transplantation in Pediatric Solid Tumors–A Pediatric Blood and Marrow Transplant Consortium Study

J. Levine, P. Shaw, M. Ozkaynak, 2008, Journal of pediatric hematology/oncology.

CTL019 Clinical Pharmacology and Biopharmaceutics in Pediatric Patients with Relapsed or Refractory (R/R) Acute Lymphoblastic Leukemia (ALL)

S. Grupp, B. Levine, C. June, 2017 .

Continuous octreotide infusion for the treatment of secretory diarrhea caused by acute intestinal graft-versus-host disease in a child.

R. Beckman, G. Yanik, J. Levine, 2000, Journal of pediatric hematology/oncology.

Acute renal failure following deferoxamine overdose

J. Flynn, J. Levine, L. Prasannan, 2003, Pediatric Nephrology.

Infectious Risk after Allogeneic Hematopoietic Cell Transplantation Complicated by Acute Graft-versus-Host Disease.

T. Braun, S. Choi, D. Couriel, 2017, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Implications of TNF-α in the pathogenesis and management of GVHD

J. Levine, 2011, International journal of hematology.

EBMT—NIH—CIBMTR Task Force position statement on standardized terminology & guidance for graft-versus-host disease assessment

E. Holler, H. Greinix, Stephanie J. Lee, 2018, Bone Marrow Transplantation.

International, Multicenter Standardization of Acute Graft-versus-Host Disease Clinical Data Collection: A Report from the Mount Sinai Acute GVHD International Consortium.

D. Porter, F. Locatelli, E. Holler, 2016, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Have we made progress in the treatment of GVHD?

J. Ferrara, J. Levine, Andrew C. Harris, 2012, Best practice & research. Clinical haematology.

Long-term follow-up of a phase I/II randomized, placebo-controlled trial of palifermin to prevent graft-versus-host disease (GVHD) after related donor allogeneic hematopoietic cell transplantation (HCT).

D. Weisdorf, B. Blazar, J. Ferrara, 2008, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

FLT3 mutational status is an independent risk factor for adverse outcomes after allogeneic transplantation in AML

T. Braun, D. Hanauer, S. Choi, 2015, Bone Marrow Transplantation.

Reduced intensity versus full myeloablative stem cell transplant for advanced CLL

T. Braun, S. Mineishi, G. Yanik, 2009, Bone Marrow Transplantation.

Hematopoietic stem cell transplantation for severe congenital neutropenia

S. Choi, J. Levine, J. Connelly, 2012, Current opinion in hematology.

MAGIC biomarkers predict long-term outcomes for steroid-resistant acute GVHD.

N. Kröger, E. Holler, Y. Efebera, 2018, Blood.

An early-biomarker algorithm predicts lethal graft-versus-host disease and survival.

N. Kröger, F. Locatelli, E. Holler, 2017, JCI insight.

Acute Graft Versus Host Disease

J. Ferrara, J. Levine, A. Renteria, 2019, Mount Sinai Expert Guides.

Development of a biomarker scoring system for use in graft-versus-host disease.

J. Ferrara, J. Levine, A. Renteria, 2016, Biomarkers in medicine.

A prognostic score for acute graft-versus-host disease based on biomarkers: a multicentre study.

T. Braun, J. Bolaños-Meade, E. Holler, 2015, The Lancet. Haematology.

Assessment of systemic and gastrointestinal tissue damage biomarkers for GVHD risk stratification

E. Holler, Z. DeFilipp, Jung-Yi Lin, 2022, Blood advances.

Acute GVHD Diagnosis and Adjudication in a Multicenter Trial: A Report From the BMT CTN 1202 Biorepository Study

J. Bolaños-Meade, Yi-Bin Chen, J. Hansen, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Revisiting mycophenolate mofetil for steroid‐refractory acute graft‐versus‐host disease: Is higher dosing effective in children?

J. Levine, 2015, Pediatric transplantation.

Improved accuracy of acute graft-versus-host disease staging among multiple centers.

Y. Efebera, S. Devine, W. Hogan, 2014, Best practice & research. Clinical haematology.

Graft-versus-host disease treatment: predictors of survival.

J. Bolaños-Meade, Juan Wu, D. Weisdorf, 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Frequency of CD4 + CD25 hi FOXP3 + Regulatory T Cells Has Diagnostic and Prognostic Value as a Biomarker for Acute Graft-Versus-Host Disease.

T. Braun, S. Mineishi, S. Choi, 2009 .

Late acute graft-versus-host disease: a prospective analysis of clinical outcomes and circulating angiogenic factors.

W. Wood, B. Storer, J. Pidala, 2016, Blood.

Allogeneic Hematopoietic Stem Cell Transplantation with Clofarabine/Busulfan × 4 (CloBu4) Conditioning Exhibits Significant Anti-Tumor Activity In Non - Remission Hematologic Malignancies, Especially In AML

S. Mineishi, S. Choi, G. Yanik, 2010 .

Acute GVHD: New approaches to clinical trial monitoring.

J. Ferrara, J. Levine, Nikolaos Spyrou, 2022, Best practice & research. Clinical haematology.

Successful bone marrow transplantation in a patient with Schimke immuno-osseous dysplasia.

E. Petty, G. Yanik, R. Hutchinson, 2000, The Journal of pediatrics.

S. Spellman, J. Panepinto, B. Logan, 2012, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Decoupling blood telomere length from age in recipients of allogeneic hematopoietic cell transplant in the BMT-CTN 1202

A. Aviv, H. Katki, Tsung-Po Lai, 2022, Frontiers in Immunology.

Metagenomic analysis of the stool microbiome in patients receiving allogeneic SCT: Loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal GvHD

R. Spang, P. Oefner, E. Holler, 2014 .

Etanercept plus methylprednisolone as initial therapy for acute graft-versus-host disease.

T. Braun, S. Mineishi, S. Choi, 2007, Blood.

Anti-CD20 Chimeric Monoclonal Antibody Treatment of Refractory Immune-Mediated Thrombocytopenia in a Patient with Chronic Graft-versus-Host Disease

G. Yanik, J. Ferrara, V. Ratanatharathorn, 2000, Annals of Internal Medicine.

Tacrolimus (FK506) and methotrexate as prophylaxis for acute graft-versus-host disease in pediatric allogeneic stem cell transplantation

G. Yanik, R. Hutchinson, J. Ferrara, 2000, Bone Marrow Transplantation.

Graft-versus-host disease in the 21st century: new perspectives on an old problem.

J. Ferrara, J. Levine, 2006, Seminars in hematology.

TNF-inhibition with etanercept for graft-versus-host disease prevention in high-risk HCT: lower TNFR1 levels correlate with better outcomes.

Scott E. Smith, T. Braun, D. Hanauer, 2012, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Three Biomarker Panel at Day 7 and 14 Can Predict Development of Grade II-IV Acute Graft-Versus-Host Disease

T. Braun, S. Hanash, S. Mineishi, 2010 .

Combination Therapy for Graft-versus-Host Disease Prophylaxis with Etanercept and Extracorporeal Photopheresis: Results of a Phase II Clinical Trial.

T. Braun, S. Choi, D. Couriel, 2016, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

A Biomarker-Based Grading System At Onset Of GvHD Predicts NRM Better Than The Modified Glucksberg Grading System

T. Braun, J. Magenau, J. Ferrara, 2013 .

The use of laparoscopic liver biopsies in pediatric patients with hepatic dysfunction following allogeneic hematopoietic stem cell transplantation

J. Greenson, D. Teitelbaum, G. Yanik, 2005, Bone Marrow Transplantation.

Double umbilical cord blood transplantation after novel myeloablative conditioning using a regimen of fludarabine, busulfan, and total lymphoid irradiation.

S. Choi, D. Couriel, G. Yanik, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Double Umbilical Cord Blood Transplantation after Novel Myeloablative Conditioning Using FluBu4/TLI

S. Choi, D. Couriel, G. Yanik, 2014 .

Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD

M. Norkin, S. Furlan, M. Pasquini, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Clinical applications of hematopoietic growth factors in pediatric oncology

L. Boxer, J. Levine, 2002, Current opinion in hematology.

Chemokines: a novel chronic GVHD target.

C. Kitko, J. Levine, 2018, Blood.

Safety and efficacy of allogeneic PBSC collection in normal pediatric donors: The Pediatric Blood and Marrow Transplant Consortium Experience (PBMTC) 1996–2003

S. Grupp, P. Anderson, M. Pulsipher, 2005, Bone Marrow Transplantation.

Donor leukocyte infusions to treat hematologic malignancy relapse following allo-SCT in a pediatric population

R. Collins, D. Porter, A. Barrett, 2008, Bone Marrow Transplantation.

A Multicenter Phase II Trial of Unrelated Donor Reduced Intensity Bone Marrow Transplantation for Children with Severe Sickle Cell Disease (SCURT): Results of the Blood and Marrow Transplant Clinical Trials Network (BMT CTN 0601) Study

Juan Wu, B. Logan, M. Eapen, 2015 .

Blood and Marrow Transplant Clinical Trials Network Report on the Development of Novel Endpoints and Selection of Promising Approaches for Graft-versus-Host Disease Prevention Trials.

M. Perales, F. Appelbaum, D. Porter, 2018, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Engraftment syndrome after allogeneic hematopoietic cell transplantation predicts poor outcomes.

T. Braun, D. Hanauer, S. Choi, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Epstein-Barr Virus–Induced Hemophagocytic Lymphohistiocytosis and X-Linked Lymphoproliferative Disease: A Mimicker of Sepsis in the Pediatric Intensive Care Unit

T. Shanley, T. Cornell, A. Filipovich, 2007, Pediatrics.

A prospective study of G-CSF primed bone marrow as a stem-cell source for allogeneic bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium (PBMTC) study.

S. Grupp, D. Billheimer, Y. Ravindranath, 2007, Blood.

Use of G‐CSF in Matched Sibling Donor Pediatric Allogeneic Transplantation: A Consensus Statement from the Children's Oncology Group (COG) Transplant Discipline Committee and Pediatric Blood and Marrow Transplant Consortium (PBMTC) Executive Committee

S. Grupp, M. Pulsipher, H. Frangoul, 2006, Pediatric blood & cancer.

Pneumocystis Jirovecii Pneumonia In Recipients Of Autologous Hematopoietic Stem Cell Transplantation: A 10-Year Cohort Study

D. Hanauer, D. Couriel, G. Yanik, 2013 .

Extramedullary relapse of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation: incidence, risk factors and outcomes

T. Braun, S. Mineishi, S. Choi, 2013, Haematologica.

Etanercept plus topical corticosteroids as initial therapy for grade 1 acute graft-versus-host disease after allogeneic hematopoietic cell transplant

T. Braun, S. Choi, S. Paczesny, 2014 .

Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia

Hans Bitter, Kevin Nguyen, Wendy Winckler, 2018, Nature Medicine.

Sensorimotor neurotoxicity associated with high-dose deferoxamine treatment.

P. Giardina, J. Levine, M. Macqueen, 1997, Journal of pediatric hematology/oncology.

Impact of conditioning regimen in allogeneic hematopoetic stem cell transplantation for children with acute myelogenous leukemia beyond first complete remission: a pediatric blood and marrow transplant consortium (PBMTC) study.

T. Koyama, M. Pulsipher, H. Frangoul, 2009, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Pulmonary, gonadal, and central nervous system status after bone marrow transplantation for sickle cell disease.

J. Scott, K. Sullivan, K. Hardy, 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Survival signal REG3&agr; prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease

M. V. D. van den Brink, J. Greenson, L. Hooper, 2018, The Journal of clinical investigation.

Etanercept, mycophenolate, denileukin, or pentostatin plus corticosteroids for acute graft-versus-host disease: a randomized phase 2 trial from the Blood and Marrow Transplant Clinical Trials Network.

M. Pasquini, M. Horowitz, J. Wingard, 2009, Blood.

Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children’s Oncology Group

S. Raimondi, S. Meshinchi, T. Alonzo, 2020, Haematologica.

Sorafenib in Combination With Standard Chemotherapy for Children With High Allelic Ratio FLT3/ITD+ Acute Myeloid Leukemia: A Report From the Children's Oncology Group Protocol AAML1031

S. Raimondi, S. Meshinchi, T. Alonzo, 2022, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Development and Validation of Blood-Based Predictive Biomarkers for Response to PD-1/PD-L1 Checkpoint Inhibitors: Evidence of a Universal Systemic Core of 3D Immunogenetic Profiling across Multiple Oncological Indications

S. Ng, A. Akoulitchev, Eleanor Hunter, 2021, medRxiv.

Reducing Treatment-Related Mortality Did Not Improve Outcomes of Allogeneic Myeloablative Hematopoietic Cell Transplantation for High-Risk Multiple Myeloma: A University of Michigan Prospective Series.

T. Braun, S. Mineishi, S. Choi, 2016, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Less (bacterial diversity) is more (deaths).

J. Levine, 2014, Blood.

Mycophenolate pharmacokinetics and association with response to acute graft-versus-host disease treatment from the Blood and Marrow Transplant Clinical Trials Network.

Juan Wu, D. Weisdorf, B. Logan, 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal graft-versus-host disease.

Daniel Wolff, Rainer Spang, Matthias Edinger, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Survival signal REG 3 a prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease

J. Greenson, L. Hooper, Ta-Chiang Liu, 2018 .

Efficacy and Safety of CTL019 in the First US Phase II Multicenter Trial in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia: Results of an Interim Analysis

Krysta D Schlis, S. Grupp, B. Levine, 2016 .

Mesenchymal stromal cell therapy for acute respiratory distress syndrome due to coronavirus disease 2019

Jung-Yi Lin, S. Itescu, J. Levine, 2022, Cytotherapy.

Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial.

T. Braun, J. Dipersio, C. Dinarello, 2014, The Lancet. Oncology.

Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium 2007.

F. Appelbaum, H. Heslop, M. Horowitz, 2007, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Challenges and opportunities for international cooperative studies in pediatric hematopoeitic cell transplantation: priorities of the Westhafen Intercontinental Group.

M. Loh, S. Grupp, C. Bollard, 2013, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Results of a phase 2, multicenter, single‐arm, open‐label study of lenalidomide in pediatric patients with relapsed or refractory acute myeloid leukemia

T. Alonzo, P. Brown, J. Levine, 2021, Pediatric blood & cancer.

Clofarabine and Busulfan Conditioning Facilitates Engraftment and Provides Significant Anti-Tumor Activity in Non-Remission Hematologic Malignancies Running Title: CloBu4 conditioning for HSCT

T. Braun, K. Elenitoba-Johnson, S. Mineishi, 2016 .

Clofarabine and busulfan conditioning facilitates engraftment and provides significant antitumor activity in nonremission hematologic malignancies.

T. Braun, K. Elenitoba-Johnson, S. Mineishi, 2011, Blood.

Microbial metabolite sensor GPR43 controls severity of experimental GVHD

M. V. D. van den Brink, Chen Liu, G. Núñez, 2018, Nature Communications.

K. Leung, M. Horowitz, J. Panepinto, 2016, Blood.

Stem cell transplantation in patients with severe congenital neutropenia with evidence of leukemic transformation

D. Roulston, G. Yanik, M. Pulsipher, 2005, Bone Marrow Transplantation.

Successful treatment of refractory immune hemolysis following unrelated cord blood transplant with Campath‐1H

G. Yanik, R. Hutchinson, J. Ferrara, 2008, Pediatric blood & cancer.

Plasma biomarkers of lower gastrointestinal and liver acute GVHD.

Thomas M Braun, Sophie Paczesny, Takanori Teshima, 2012, Blood.

Elafin Is a Biomarker of Graft-Versus-Host Disease of the Skin

Thomas M Braun, Hong Wang, Ying Wang, 2008, Science Translational Medicine.

A biomarker panel for acute graft-versus-host disease.

Thomas M Braun, Dawn Jones, Sophie Paczesny, 2009, Blood.

Plasma biomarkers in GVHD: a new era?

T. Braun, S. Paczesny, J. Levine, 2009 .

Plasma biomarkers in graft-versus-host disease: a new era?

Thomas M Braun, Sophie Paczesny, T. Braun, 2009, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Lowered-intensity preparative regimen for allogeneic stem cell transplantation delays acute graft-versus-host disease but does not improve outcome for advanced hematologic malignancy.

T. Braun, G. Yanik, R. Hutchinson, 2003, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

14 A phase I/II study of recombinant human keratinocyte growth factor (KGF) in patients with high risk hematologic malignancies undergoing mismatched related or unrelated donor transplant

T. Braun, M. Becker, G. Yanik, 2003 .

Acute toxicities of unrelated bone marrow versus peripheral blood stem cell donation: results of a prospective trial from the National Marrow Donor Program.

J. Wingard, D. Stroncek, B. Shaw, 2013, Blood.

Lower risk for serious adverse events and no increased risk for cancer after PBSC vs BM donation.

B. Shaw, B. Logan, M. Pulsipher, 2014, Blood.

Prospective T rial o f C hemotherapy a nd D onor L eukocyte Infusions f or R elapse o f A dvanced M yeloid M alignancies After A llogeneic S tem-Cell T ransplantation

T. Braun, K. Cornetta, D. Porter, 2002 .

A refined risk score for acute graft-versus-host disease that predicts response to initial therapy, survival, and transplant-related mortality.

M. Robin, M. Pasquini, Richard J. Jones, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Evaluation of elafin as a prognostic biomarker in acute graft-versus-host disease.

S. Grupp, Yi-Bin Chen, Z. DeFilipp, 2021, Transplantation and cellular therapy.

Biomarker-guided preemption of steroid-refractory graft-versus-host disease with α-1-antitrypsin.

E. Holler, Yi-Bin Chen, Z. DeFilipp, 2020, Blood advances.

Disease Risk and GVHD Biomarkers Can Stratify Patients For Risk of Relapse and Non-Relapse Mortality Post Hematopoietic Cell Transplant

N. Kröger, Yi-Bin Chen, M. Qayed, 2020, Leukemia.

The MAGIC algorithm probability is a validated response biomarker of treatment of acute graft-versus-host disease.

S. Grupp, Z. DeFilipp, K. Sigel, 2019, Blood advances.

Regenerating islet-derived 3-alpha is a biomarker of gastrointestinal graft-versus-host disease.

Thomas M Braun, Sophie Paczesny, Elisabeth Huber, 2011, Blood.

Change in plasma tumor necrosis factor receptor 1 levels in the first week after myeloablative allogeneic transplantation correlates with severity and incidence of GVHD and survival.

Thomas Braun, Dawn Jones, Sophie Paczesny, 2008, Blood.

Lymphoblastic Lymphoma A Comparison of Allogeneic and Autologous Bone Marrow Transplant for

J. Armitage, J. Vose, M. Horowitz, 2013 .

A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphoma.

Alan M. Miller, J. Armitage, J. Vose, 2003, Blood.

Acute graft-versus-host disease of the gut: considerations for the gastroenterologist

J. Colombel, J. Ferrara, J. Levine, 2017, Nature Reviews Gastroenterology & Hepatology.

Randomized Multicenter Trial of Sirolimus vs. Prednisone as Initial Therapy for Standard Risk Acute GVHD: BMT CTN 1501.

E. Leifer, M. Horowitz, J. Pidala, 2019, Blood.

Phase II Trial of Vorinostat plus Tacrolimus & Mycophenolate to prevent Graft versus Host Disease Following Reduced Intensity Conditioning Related Donor Allogeneic Transplant Blood and Marrow Transplantation Program University of Michigan Comprehensive Cancer Center

T. Braun, S. Choi, D. Couriel, 2012 .

TNF receptor inhibitor therapy for the treatment of children with idiopathic pneumonia syndrome (IPS): A joint Pediatric Blood and Marrow Transplant Consortium (PBMTC) and Children’s Oncology Group (COG) study (ASCT0521)

S. Grupp, B. Langholz, E. White, 2015 .

Combination Therapy for GVHD Prophylaxis with Etanercept and Extracorporeal Photopheresis: Results of a Phase II Clinical Trial

S. Choi, D. Couriel, G. Yanik, 2016 .

Treatment versus transplant for challenging hematologic disorders.

R. Brodsky, J. Levine, C. Parker, 2009, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Frequency of CD4(+)CD25(hi)FOXP3(+) regulatory T cells has diagnostic and prognostic value as a biomarker for acute graft-versus-host-disease.

T. Braun, S. Mineishi, S. Choi, 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Effect of myeloablative bone marrow transplantation on growth in children with sickle cell anaemia: results of the multicenter study of haematopoietic cell transplantation for sickle cell anaemia

S. Donfield, S. Davies, D. Margolis, 2007, British journal of haematology.

Indications for hematopoietic cell transplantation for children with severe congenital neutropenia

S. Choi, J. Levine, 2010, Pediatric transplantation.

Allogeneic transplantation with myeloablative FluBu4 conditioning improves survival compared to reduced intensity FluBu2 conditioning for acute myeloid leukemia in remission

T. Braun, S. Mineishi, S. Choi, 2015, Annals of Hematology.

Making the genomic leap in HCT: application of second-generation sequencing to clinical advances in hematopoietic cell transplantation

H. Hakonarson, Y. Li, B. Keating, 2013, European Journal of Human Genetics.

A Prospective Study of G-CSF Primed Bone Marrow from Pediatric Donors as a Stem Cell Source for Allogeneic Bone Marrow Transplant: A Pediatric Blood and Marrow Transplant Consortium (PBMTC) Study.

S. Grupp, D. Billheimer, Y. Ravindranath, 2005 .

Peritransplant palifermin use and lymphocyte recovery after T‐cell replete, matched related allogeneic hematopoietic cell transplantation

D. Weisdorf, B. Blazar, M. Verneris, 2011, American journal of hematology.

The Addition of Bortezomib to Standard Chemotherapy for Pediatric Acute Myeloid Leukemia Has Increased Toxicity without Therapeutic Benefit: A Report from the Children's Oncology Group

S. Raimondi, S. Meshinchi, T. Alonzo, 2016 .

Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802.

W. Wood, J. Pidala, E. Holler, 2018, Blood advances.

Phase I study of tandem high‐dose chemotherapy with autologous peripheral blood stem cell rescue for children with recurrent brain tumors: A pediatric blood and marrow transplant consortium study

T. MacDonald, A. Bendel, D. Wall, 2011, Pediatric blood & cancer.

Current and Emerging Targeted Therapies for Acute Graft-Versus-Host Disease

J. Levine, Stelios Kasikis, Aaron M. Etra, 2020, BioDrugs.

severity and incidence of GVHD and survival week after myeloablative allogeneic transplantation correlates with Change in plasma tumor necrosis factor receptor 1 levels in the first

T. Braun, S. Mineishi, S. Paczesny, 2013 .

Comparison of total body irradiation versus non-total body irradiation containing regimens for de novo acute myeloid leukemia in children

S. Gadalla, M. MacMillan, S. Davies, 2020, Haematologica.

Adolescent and young adult (AYA) versus pediatric patients with acute leukemia have a significantly increased risk of acute GVHD following unrelated donor (URD) stem cell transplantation (SCT): the Children’s Oncology Group experience

Lingyun Ji, M. Cairo, M. Pulsipher, 2022, Bone Marrow Transplantation.

C. Kitko, J. Levine, P. Carpenter, 2011, Pediatric transplantation.

Lymphocyte phenotype during therapy for acute graft-versus-host disease: a brief report from BMT-CTN 0302.

J. Bolaños-Meade, Juan Wu, D. Weisdorf, 2013, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Marrow Transplant Clinical Trials Network phasecorticosteroids for acute graft-versus-host disease : a randomized Etanercept , mycophenolate , denileukin , or pentostatin plus

M. Pasquini, M. Horowitz, J. Wingard, 2009 .

S112: TISAGENLECLEUCEL IN PEDIATRIC AND YOUNG ADULT PATIENTS (PTS) WITH RELAPSED/REFRACTORY (R/R) B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL): FINAL ANALYSES FROM THE ELIANA STUDY

S. Rives, A. Baruchel, S. Grupp, 2022, HemaSphere.

Malignant triton tumor in a patient with Li‐Fraumeni syndrome and a novel TP53 mutation

E. Petty, W. Kohlmann, J. Levine, 2007, Pediatric blood & cancer.

Mesenchymal stromal cell therapy induces high responses and survival in children with steroid refractory GVHD and poor risk biomarkers

S. Grupp, M. Qayed, G. Yanik, 2021, Bone Marrow Transplantation.

Prognostic Biomarkers for Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome in Myeloablative Allogeneic Hematopoietic Cell Transplantation: Results from the Blood and Marrow Transplant Clinical Trials Network 1202 Study

M. Perales, S. Putta, W. Saber, 2022, Transplantation and cellular therapy.

In vivo IL-12/IL-23p40 neutralization blocks Th1/Th17 response after allogeneic hematopoietic cell transplantation

H. Jim, J. Pidala, A. Mishra, 2017, Haematologica.

Phase 3 clinical trial of steroids/mycophenolate mofetil vs steroids/placebo as therapy for acute GVHD: BMT CTN 0802.

P. Westervelt, M. Pasquini, M. Horowitz, 2014, Blood.

Significant improvement in survival after unrelated donor hematopoietic cell transplantation in the recent era.

R. Hartzman, G. Switzer, S. Devine, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Priorities for Improving Outcomes for Non-Malignant Blood Diseases: A Report from the Blood and Marrow Transplant Clinical Trials Network.

H. Heslop, S. Devine, G. Yanik, 2020, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Effective treatment of low risk acute GVHD with itacitinib monotherapy.

Z. DeFilipp, A. Alousi, M. Qayed, 2022, Blood.

Children's Oncology Group's 2013 blueprint for research: Stem cell transplantation

S. Grupp, B. Langholz, M. Pulsipher, 2013, Pediatric blood & cancer.

Amphiregulin Improves Stratification of the Refined Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN 0302/0802

W. Wood, J. Pidala, E. Holler, 2017 .

Sorafenib in Combination with Standard Chemotherapy for Children with High Allelic Ratio FLT3/ITD+ AML Improves Event-Free Survival and Reduces Relapse Risk: A Report from the Children's Oncology Group Protocol AAML1031

S. Raimondi, S. Meshinchi, T. Alonzo, 2019, Blood.

Lower intensity of preparative regimen for allogeneic stem cell transplantation from related donor in patients with advanced hematologic malignancy is associated with poor outcome

G. Yanik, R. Hutchinson, J. Ferrara, 2000 .

Reg3α concentrations at day of allogeneic stem cell transplantation predict outcome and correlate with early antibiotic use

E. Holler, A. Hiergeist, M. Edinger, 2022, Blood advances.

Microbial metabolite sensor GPR43 controls severity of experimental GVHD

M. V. D. van den Brink, Chen Liu, G. Núñez, 2018, Nature Communications.

A validated pediatric disease risk index for allogeneic hematopoietic cell transplantation.

J. Chewning, M. Verneris, M. Qayed, 2020, Blood.

A Multi-Center, Randomized, Double Blind, Phase III Clinical Trial Comparing Steroids/Placebo Vs. Steroids/Mycophenolate Mofetil As Initial Therapy for Acute Graft-Versus-Host Disease. Blood and Marrow Transplant Clinical Trials Network Study 0802

P. Westervelt, M. Pasquini, M. Horowitz, 2013 .

Comparison of Gvhd Biomarker Algorithms for Predicting Lethal Gvhd and Non-Relapse Mortality

E. Holler, Yi-Bin Chen, Jung-Yi Lin, 2019, Biology of Blood and Marrow Transplantation.

Acute Gvhd Diagnosis and Adjudication in a Multicenter Trial – a Report from the BMT CTN 1202 Biorepository Study

Yi-Bin Chen, J. Hansen, W. Saber, 2019, Biology of Blood and Marrow Transplantation.

BMT CTN 0302: A Phase II Randomized Trial Evaluating Etanercept, Mycophenolate Mofetil (MMF), Denileukin Diftitox, and Pentostatin in Combination with Corticosteroids in 180 Patients (pts) with Newly Diagnosed Acute Graft Vs. Host Disease (aGVHD)

M. Horowitz, J. Wingard, D. Weisdorf, 2008 .

Predictive value of bronchiolitis obliterans syndrome stage 0p in chronic graft-versus-host disease of the lung.

T. Braun, D. Couriel, G. Yanik, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Survival Following Etanercept Therapy for the Treatment of Idiopathic Pneumonia Syndrome Post Allogeneic Stem Cell Transplantation.

G. Yanik, J. Ferrara, J. Levine, 2004 .

Impact of psychological screening on routine outpatient care of hematopoietic cell transplantation survivors.

F. Hoodin, C. Kitko, J. Levine, 2013, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Myeloablative Conditioning with Clofarabine and Busulfan X 4 (CloBu4) Is Well Tolerated, Facilitates Secure Engraftment, and Exhibits Significant Anti-Tumor Activity against Non-Remission Hematologic Malignancies Including AML.

T. Braun, S. Mineishi, S. Choi, 2008 .

Determining a maximum tolerated cumulative dose: dose reassignment within the TITE-CRM.

T. Braun, J. Ferrara, J. Levine, 2003, Controlled clinical trials.

An early-biomarker algorithm predicts lethal graft-versus-host disease and survival.

N. Kröger, F. Locatelli, E. Holler, 2018, JCI insight.

Children's Oncology Group's 2023 blueprint for research: Cellular therapy and stem cell transplantation

J. Chewning, C. Bollard, T. Fry, 2023, Pediatric blood & cancer.

Stem cell transplantation in patients with severe congenital neutropenia without evidence of leukemic transformation.

H. Mandel, M. Freedman, K. Welte, 2000, Blood.

Cytokine-mobilized allogeneic peripheral blood stem cell transplants in children result in rapid engraftment and a high incidence of chronic GVHD

M. Koehler, G. Yanik, R. Hutchinson, 2000, Bone Marrow Transplantation.

Long-term followup of a phase I/II randomized, placebo-controlled trial of palifermin to prevent graft-versus-host disease (GVHD) after related donor allogeneic hematopoietic cell transplantation (HCT)

B. Blazar, J. Ferrara, J. Levine, 2008 .

Phase 2 study of natalizumab plus standard corticosteroid treatment for high-risk acute graft-versus-host disease

S. Grupp, E. Holler, Z. DeFilipp, 2023, Blood advances.

Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency.

David A. Williams, J B Lowe, D. Williams, 2000, Blood.

Extramedullary Relapse In Acute Leukemia Following Allogeneic Hematopoietic Stem Cell Transplantation: Incidence, Risk Factors And Outcomes

T. Braun, S. Mineishi, G. Yanik, 2010 .

The impact of soluble tumor necrosis factor receptor etanercept on the treatment of idiopathic pneumonia syndrome after allogeneic hematopoietic stem cell transplantation.

T. Braun, E. White, G. Yanik, 2008, Blood.

M. Pasquini, M. Horowitz, J. Wingard, 2009, Blood.

A New Approach to Therapy for Acute GVHD

J. Levine, E. John, L. James, 2008 .

ST2 as a marker for risk of therapy-resistant graft-versus-host disease and death.

T. Braun, S. Hanash, J. Ritz, 2013, The New England journal of medicine.

Infectious Risk after Allogeneic Hematopoietic Cell Transplantation Complicated by Acute Graft-versus-Host Disease.

T. Braun, S. Choi, D. Couriel, 2017, Biology of Blood and Marrow Transplantation.

More evidence for low-dose IL-2 for chronic GVHD in children

J. Levine, 2023, Blood advances.

Less (bacterial diversity) is more (deaths).

J. Levine, 2014, Blood.

Change in plasma tumor necrosis factor receptor 1 levels in the first week after myeloablative allogeneic transplantation correlates with severity and incidence of GVHD and survival.

T. Braun, S. Mineishi, S. Choi, 2008, Blood.

Acute toxicities of unrelated bone marrow versus peripheral blood stem cell donation: results of a prospective trial from the National Marrow Donor Program.

J. Wingard, D. Stroncek, B. Shaw, 2013, Blood.

Elafin Is a Biomarker of Graft-Versus-Host Disease of the Skin

T. Braun, S. Hanash, D. Hanauer, 2010, Science Translational Medicine.

Impact of Dose Intensification of FluBu2 to FluBu4 on Transplant Related Mortality, Relapse, and Survival After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia in Remission

T. Braun, S. Mineishi, S. Choi, 2013 .

Mycophenolate pharmacokinetics and association with response to acute graft-versus-host disease treatment from the Blood and Marrow Transplant Clinical Trials Network.

J. Bolaños-Meade, Juan Wu, D. Weisdorf, 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Successful treatment of refractory immune hemolysis following unrelated cord blood transplant with Campath‐1H

G. Yanik, R. Hutchinson, J. Ferrara, 2008, Pediatric blood & cancer.

Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802.

W. Wood, J. Pidala, J. Bolaños-Meade, 2018, Blood advances.

Etanercept plus topical corticosteroids as initial therapy for grade one acute graft-versus-host disease after allogeneic hematopoietic cell transplantation.

T. Braun, S. Choi, S. Paczesny, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

The utility of biomarkers in acute GVHD prognostication

S. Grupp, E. Holler, Z. DeFilipp, 2023, Blood advances.

Development of a biomarker scoring system for use in graft-versus-host disease.

J. Ferrara, J. Levine, A. Renteria, 2016, Biomarkers in medicine.

Clinical Applications for Biomarkers of Acute and Chronic Graft vs. Host Disease

S. Paczesny, J. Levine, S. Sarantopoulos, 2012 .

SSOP typing of the Tenth International Histocompatibility Workshop reference cell lines for HLA-C alleles.

S. Yang, S. Y. Yang, J. Levine, 1994, Tissue antigens.