Robert D Mazzola

Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: conformational constraint to favor a bioactive conformation.

William Greenlee, Lynn Hyde, Xia Chen, 2012, Journal of medicinal chemistry.

Discovery of potent iminoheterocycle BACE1 inhibitors.

Brian McKittrick, Andrew Stamford, Xia Chen, 2014, Bioorganic & medicinal chemistry letters.

Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket.

Brian McKittrick, Zhuyan Guo, Xiaoda Niu, 2008, Bioorganic & medicinal chemistry letters.