Lili Zhang

Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: conformational constraint to favor a bioactive conformation.

William Greenlee, Lynn Hyde, Xia Chen, 2012, Journal of medicinal chemistry.

Discovery of potent iminoheterocycle BACE1 inhibitors.

Brian McKittrick, Andrew Stamford, Xia Chen, 2014, Bioorganic & medicinal chemistry letters.

Tetrahydroquinoline sulfonamides as γ-secretase inhibitors

Zhiqiang Zhao, Wei Li, William J. Greenlee, 2007 .

Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization.

Andrew Stamford, William Greenlee, Guoqing Li, 2010, Bioorganic & medicinal chemistry letters.

Chronic Treatment with the γ-Secretase Inhibitor LY-411,575 Inhibits β-Amyloid Peptide Production and Alters Lymphopoiesis and Intestinal Cell Differentiation*

Jay S. Fine, G. Higgins, M. Pinzon-Ortiz, 2004, Journal of Biological Chemistry.

Discovery of 2,4,6-trisubstituted N-arylsulfonyl piperidines as γ-secretase inhibitors

Ruo Xu, Zhiqiang Zhao, Murali Rajagopalan, 2007 .

Small conformationally restricted piperidine N-arylsulfonamides as orally active gamma-secretase inhibitors.

Zhiqiang Zhao, William J Greenlee, Murali Rajagopalan, 2007, Bioorganic & medicinal chemistry letters.