C R Beddell

发表

Crystallographic investigation of the cooperative interaction between trimethoprim, reduced cofactor and dihydrofolate reductase

C. Beddell, J. Champness, D. Stammers, 1986, FEBS letters.

A pattern recognition approach to the comparison of PMR and clinical chemical data for classification of nephrotoxicity.

J C Lindon, C. Beddell, J. Lindon, 1990, Journal of pharmaceutical and biomedical analysis.

Pattern recognition analysis of high resolution 1H NMR spectra of urine. A nonlinear mapping approach to the classification of toxicological data

J C Lindon, C. Beddell, J. Nicholson, 1990, NMR in biomedicine.

COMPOUNDS DESIGNED TO FIT A SITE OF KNOWN STRUCTURE IN HUMAN HAEMOGLOBIN

P J Goodford, C. Beddell, P. Goodford, 1976, British journal of pharmacology.

Mapping the biochemical trajectory of nephrotoxicity by pattern recognition of NMR urinanalysis

E Holmes, J C Lindon, C. Beddell, 1992, NMR in biomedicine.

Nuclear magnetic resonance spectroscopy and pattern recognition analysis of the biochemical processes associated with the progression of and recovery from nephrotoxic lesions in the rat induced by mercury(II) chloride and 2-bromoethanamine.

E Holmes, J C Lindon, C. Beddell, 1992, Molecular pharmacology.

Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues.

L. Kuyper, B. Roth, D. Baccanari, 1982, Journal of medicinal chemistry.

The binding of trimethoprim to bacterial dihydrofolate reductase

P J Goodford, C. Beddell, J. Champness, 1981, FEBS letters.

NMR spectroscopy of human post mortem cerebrospinal fluid: Distinction of Alzheimer's disease from control using pattern recognition and statistics

J C Lindon, C. Beddell, N. Cairns, 1993, NMR in biomedicine.

Application of pattern recognition methods to the analysis and classification of toxicological data derived from proton nuclear magnetic resonance spectroscopy of urine.

J C Lindon, C. Beddell, J. Lindon, 1991, Molecular pharmacology.

SPECIES DIFFERENCES IN THE BINDING OF COMPOUNDS DESIGNED TO FIT A SITE OF KNOWN STRUCTURE IN ADULT HUMAN HAEMOGLOBIN

P J Goodford, C. Beddell, D. Stammers, 1979, British journal of pharmacology.

Pattern recognition classification of the site of nephrotoxicity based on metabolic data derived from proton nuclear magnetic resonance spectra of urine.

J C Lindon, C. Beddell, J. Lindon, 1994, Molecular pharmacology.

Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim.

J M Burridge, C. Beddell, J. Champness, 1985, The Journal of biological chemistry.