Edward J Brnardic

发表

Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain.

Paul Zuck, K. K. Nanda, D. Henze, 2014, Journal of medicinal chemistry.

3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6.

Lawrence C Kuo, Laura Sepp-Lorenzino, Weikang Tao, 2006, Bioorganic & medicinal chemistry letters.

Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors.

Lawrence C Kuo, Laura Sepp-Lorenzino, Weikang Tao, 2007, Bioorganic & medicinal chemistry letters.

Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid-4 (TRPV4).

Carl A. Brooks, D. Holt, D. Behm, 2018, Journal of medicinal chemistry.

Recent advances in TRPV4 agonists and antagonists.

D. Behm, B. Lawhorn, Edward J Brnardic, 2020, Bioorganic & medicinal chemistry letters.

TRPV4 antagonists: a patent review (2015-2020).

D. Behm, B. Lawhorn, Edward J Brnardic, 2021, Expert opinion on therapeutic patents.

Identification and in Vivo Evaluation of Liver X Receptor β-Selective Agonists for the Potential Treatment of Alzheimer's Disease.

K. K. Nanda, M. Rudd, J. Uslaner, 2016, Journal of medicinal chemistry.

3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts.

Sarah L. Huszar, J. Uslaner, C. Culberson, 2010, Bioorganic & medicinal chemistry letters.

Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model.

Carl A. Brooks, D. Holt, D. Behm, 2018, Journal of medicinal chemistry.

Discovery of GSK3527497: A candidate for the inhibition of Transient Receptor Potential Vanilloid-4 (TRPV4).

Carl A. Brooks, D. Holt, D. Behm, 2019, Journal of medicinal chemistry.

Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor.

Sarah L. Huszar, J. Uslaner, M. Jacobson, 2010, ACS medicinal chemistry letters.