Beth L Pietrak

Conformationally biased P3 amide replacements of beta-secretase inhibitors.

M Katharine Holloway, S. Stachel, C. Coburn, 2006, Bioorganic & medicinal chemistry letters.

Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation.

Alison R. Gregro, Georgia B McGaughey, M Katharine Holloway, 2007, Bioorganic & medicinal chemistry letters.

Macrocyclic inhibitors of beta-secretase: functional activity in an animal model.

M Katharine Holloway, Lixia Jin, Michelle Crouthamel, 2006, Journal of medicinal chemistry.

Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors.

Lawrence C Kuo, Daniel R McMasters, James C Barrow, 2004, Journal of medicinal chemistry.

Biochemical and cell-based assays for characterization of BACE-1 inhibitors.

Xiao-Ping Shi, Amy S Espeseth, Min Xu, 2005, Analytical biochemistry.

BACE-1 inhibition by a series of psi[CH2NH] reduced amide isosteres.

Lixia Jin, Qian Huang, Janet Lineberger, 2006, Bioorganic & medicinal chemistry letters.

Evaluating scoring functions for docking and designing beta-secretase inhibitors.

Georgia B McGaughey, Ming-Chih Crouthamel, Shawn J Stachel, 2007, Bioorganic & medicinal chemistry letters.