Lili Chen

发表

Discovery and optimization of 1,3,4-trisubstituted-pyrazolone derivatives as novel, potent, and nonsteroidal farnesoid X receptor (FXR) selective antagonists.

Ying Yu, Zhenting Gao, Wenzhong Yan, 2012, Journal of medicinal chemistry.

Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase N Terminus Is Indispensable for Proteolytic Activity but Not for Enzyme Dimerization

Li Du, Jing Chen, Xu Shen, 2005, Journal of Biological Chemistry.

(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice

Jing Chen, Jiming Ye, Mingyue Zheng, 2012, PloS one.

Techniques used for the discovery of therapeutic compounds: The case of SARS

Xu Shen, Hualiang Jiang, Kaixian Chen, 2006, Drug Discovery Today: Technologies.

Structure-based discovery of inhibitors of the YycG histidine kinase: new chemical leads to combat Staphylococcus epidermidis infections.

Zhiqiang Qin, Antoine Danchin, Yang Wu, 2006, BMC microbiology.

Cinanserin Is an Inhibitor of the 3C-Like Proteinase of Severe Acute Respiratory Syndrome Coronavirus and Strongly Reduces Virus Replication In Vitro

Christian Drosten, Burkhard Ludewig, Elke Scandella, 2005, Journal of Virology.

Butyl 4-(butyryloxy)benzoate functions as a new selective estrogen receptor β agonist and induces GLUT4 expression in CHO-K1 cells

Jin Huang, Xu Shen, Hong Shen, 2008, The Journal of Steroid Biochemistry and Molecular Biology.

IdentificationofNovelFalcipain-2InhibitorsasPotentialAntimalarialAgentsthroughStructure-Based Virtual Screening

Lili Chen, Jian Li, Hualiang Jiang, 2009 .

Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode.

Li Li, Xu Shen, Hualiang Jiang, 2011, Journal of molecular biology.

Discovering Severe Acute Respiratory Syndrome Coronavirus 3CL Protease Inhibitors: Virtual Screening, Surface Plasmon Resonance, and Fluorescence Resonance Energy Transfer Assays

Xu Shen, Jianhua Shen, Shuai Chen, 2006, SLAS Discovery.

Binding interaction of quercetin-3-β-galactoside and its synthetic derivatives with SARS-CoV 3CLpro: Structure–activity relationship studies reveal salient pharmacophore features

Cheng Luo, Weiliang Zhu, Jian Li, 2006, Bioorganic & Medicinal Chemistry.

Identification of novel falcipain-2 inhibitors as potential antimalarial agents through structure-based virtual screening.

Honglin Li, Jin Huang, Jin Zhu, 2009, Journal of medicinal chemistry.

Discovery of Helicobacter pylori shikimate kinase inhibitors: bioassay and molecular modeling.

Jian Zhang, Xu Shen, Cong Han, 2007, Bioorganic & medicinal chemistry.

Structural and Functional Characterization of Falcipain-2, a Hemoglobinase from the Malarial Parasite Plasmodium falciparum*

Xu Shen, Rolf Hilgenfeld, Hualiang Jiang, 2006, Journal of Biological Chemistry.

Discovery of new non-steroidal FXR ligands via a virtual screening workflow based on Phase shape and induced fit docking.

Weihua Li, Mingyue Zheng, Yun Tang, 2012, Bioorganic & medicinal chemistry letters.