A. Portner

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Crystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase

S. Crennell, G. Taylor, T. Takimoto, 2001, Nature Structural Biology.

Cytoplasmic Domain of Sendai Virus HN Protein Contains a Specific Sequence Required for Its Incorporation into Virions

T. Takimoto, A. Portner, T. Bousse, 1998, Journal of Virology.

Glycosylation of the hemagglutinin-neuraminidase glycoprotein of human parainfluenza virus type 1 affects its functional but not its antigenic properties.

A. Portner, W. Gorman, C. Pridgen, 1991, Virology.

Isolation of a biologically active soluble form of the hemagglutinin-neuraminidase protein of Sendai virus

W. G. Laver, K. Murti, S. Thompson, 1988, Journal of virology.

Fusion of a Sendai mutant deficient in HN protein (ts271) with cardiolipin liposomes.

A. Portner, J. Lenard, S. Gibson, 1988, Virology.

Sendai virus recombinant vaccine expressing a secreted, unconstrained respiratory syncytial virus fusion protein protects against RSV in cotton rats.

K. Boyd, C. Russell, S. Surman, 2015, International immunology.

Three variations in the cell surface expression of the haemagglutinin-neuraminidase glycoprotein of Sendai virus.

L. Roux, P. Beffy, A. Portner, 1985, The Journal of general virology.

Analysis of the primary T-cell response to Sendai virus infection in C57BL/6 mice: CD4+ T-cell recognition is directed predominantly to the hemagglutinin-neuraminidase glycoprotein

T. Hogg, J. Katz, D. Woodland, 1994, Journal of Virology.

Localization of proteins on viral nucleocapsids using immunoelectron microscopy

K. Murti, A. Portner, K. Troughton, 1985 .

Role of Matrix and Fusion Proteins in Budding of Sendai Virus

K. Murti, T. Takimoto, A. Portner, 2001, Journal of Virology.

The Novel Parainfluenza Virus Hemagglutinin-Neuraminidase Inhibitor BCX 2798 Prevents Lethal Synergism between a Paramyxovirus and Streptococcus pneumoniae

J. McCullers, K. Boyd, T. Takimoto, 2005, Antimicrobial Agents and Chemotherapy.

Efficacy of Novel Hemagglutinin-Neuraminidase Inhibitors BCX 2798 and BCX 2855 against Human Parainfluenza Viruses In Vitro and In Vivo

G. Taylor, T. Takimoto, A. Portner, 2004, Antimicrobial Agents and Chemotherapy.

Sendai virus-based RSV vaccine protects against RSV challenge in an in vivo maternal antibody model.

P. Dormitzer, C. Russell, J. Devincenzo, 2014, Vaccine.

Human PIV-2 recombinant Sendai virus (rSeV) elicits durable immunity and combines with two additional rSeVs to protect against hPIV-1, hPIV-2, hPIV-3, and RSV.

C. Russell, V. Mishin, S. Surman, 2009, Vaccine.

Expression of Sendai virus defective-interfering genomes with internal deletions.

C. Hsu, K. Gupta, A. Portner, 1985, Virology.

Properties of incomplete Sendai virions and subgenomic viral RNAs.

A. Portner, R. Darlington, D. Kingsbury, 1970, Virology.

Nontypeable Haemophilus influenzae and Streptococcus pneumoniae bind respiratory syncytial virus glycoprotein.

E. Adderson, A. Portner, Yan Wang, 2006, Journal of medical microbiology.

On the genesis of incomplete Sendai virions.

A. Portner, D. Kingsbury, 1970, Virology.

Receptor Specificities of Human Respiroviruses

M. Uchikawa, Yasuo Suzuki, Takashi Suzuki, 2001, Journal of Virology.

The nucleoproteins of human parainfluenza virus type 1 and Sendai virus share amino acid sequences and antigenic and structural determinants.

D. S. Gill, A. Portner, D. Lyn, 1991, The Journal of general virology.

The P genes of human parainfluenza virus type 1 clinical isolates are polycistronic and microheterogeneous.

U. Power, A. Portner, K. Ryan, 1992, Virology.

The Novel Parainﬂuenza Virus Hemagglutinin-Neuraminidase Inhibitor BCX 2798 Prevents Lethal Synergism between a Paramyxovirus and Streptococcus pneumoniae

J. McCullers, K. Boyd, T. Takimoto, 2004 .

Drastic immunoreactivity changes between the immature and mature forms of the Sendai virus HN and F0 glycoproteins

L. Roux, A. Portner, G. Mottet, 1986, Journal of virology.

Crystallization of Newcastle disease virus hemagglutinin-neuraminidase glycoprotein.

S. Crennell, G. Taylor, T. Takimoto, 2000, Virology.

Receptor Speciﬁcities of Human Respiroviruses

M. Uchikawa, Yasuo Suzuki, Takashi Suzuki, 2001 .

A temperature-sensitive mutant of Sendai virus with an altered hemagglutinin-neuraminidase polypeptide: consequences for virus assembly and cytopathology.

A. Portner, R. Scroggs, D. Kingsbury, 1975, Virology.

Recombinant Sendai Virus Expressing the G Glycoprotein of Respiratory Syncytial Virus (RSV) Elicits Immune Protection against RSV

K. Boyd, S. Krishnamurthy, Y. Nagai, 2004, Journal of Virology.

Charge heterogeneity in polypeptides of negative strand RNA viruses.

C. Hsu, R. Raghow, S. Clark, 1978, Virology.

Receptor-binding specificity of the human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein.

J. McCullers, G. Taylor, V. Mishin, 2012, Glycobiology.

The hemagglutinin-neuraminidase glycoproteins of human parainfluenza virus type 1 and Sendai virus have high structure-function similarity with limited antigenic cross-reactivity.

D. S. Gill, A. Portner, R. Scroggs, 1990, Virology.

Loss of the N-Linked Glycan at Residue 173 of Human Parainfluenza Virus Type 1 Hemagglutinin-Neuraminidase Exposes a Second Receptor-Binding Site

G. Taylor, K. Boyd, K. Murti, 2008, Journal of Virology.

A plasmid that improves the efficiency of foreign gene expression by intracellular T7 RNA polymerase.

A. Portner, T. Takahashi, K. Ryan, 1992, Genetic analysis, techniques and applications.

The fusion glycoprotein of Sendai virus: sequence analysis of an epitope involved in fusion and virus neutralization.

C. Naeve, A. Portner, R. Scroggs, 1987, Virology.

The human parainfluenza virus type-1 prototypic strain contains a heat-labile hemagglutinin-neuraminidase protein.

T. Takimoto, A. Portner, 1994, Virus research.

Identification of transcriptive and replicative intermediates in Sendai virus-infected cells.

A. Portner, D. Kingsbury, 1972, Virology.

A Recombinant Sendai Virus Is Controlled by CD4+ Effector T Cells Responding to a Secreted Human Immunodeficiency Virus Type 1 Envelope Glycoprotein

Scott A. Brown, P. Doherty, S. Surman, 2007, Journal of Virology.

Differentially Regulated Interferon Response Determines the Outcome of Newcastle Disease Virus Infection in Normal and Tumor Cell Lines

S. Krishnamurthy, T. Takimoto, A. Portner, 2006, Journal of Virology.

Distinct functions of antigenic sites of the HN glycoprotein of Sendai virus.

D. Metzger, A. Portner, R. Scroggs, 1987, Virology.

Localization of P, NP, and M proteins on Sendai virus nucleocapsid using immunogold labeling.

K. Murti, A. Portner, 1986, Virology.

Functions of Sendai virus nucleocapsid polypeptides: enzymatic activities in nucleocapsids following cleavage of polypeptide P by Staphylococcus aureus protease V8.

V. G. Chinchar, A. Portner, 1981, Virology.

Ribonucleic Acid Transcriptases in Sendai Virions and Infected Cells

A. Portner, H. O. Stone, D. Kingsbury, 1971, Journal of virology.

Regions on the hemagglutinin-neuraminidase proteins of human parainfluenza virus type-1 and Sendai virus important for membrane fusion.

T. Takimoto, A. Portner, T. Bousse, 1994, Virology.

Crystallization of Sendai virus HN protein complexed with monoclonal antibody Fab fragments.

W. G. Laver, K. Murti, S. Thompson, 1989, Virology.

MONOCLONAL ANTIBODIES AS PROBES OF THE ANTIGENIC STRUCTURE AND FUNCTIONS OF SENDAI VIRUS GLYCOPROTEINS1

A. Portner, 1984 .

Regulatory events in the synthesis of Sendai virus polypeptides and their assembly into virions.

A. Portner, D. Kingsbury, 1976, Virology.

Isolation and Characterization of Sendai Virus Temperature-Sensitive Mutants

P. Marx, A. Portner, D. Kingsbury, 1974, Journal of virology.

Efficacy of the novel parainfluenza virus haemagglutinin-neuraminidase inhibitor BCX 2798 in mice – further evaluation

K. Boyd, Makiko Watanabe, A. Portner, 2009, Antiviral therapy.

Localization of P protein binding sites on the Sendai virus nucleocapsid.

K. Murti, A. Portner, K. Ryan, 1990, The Journal of general virology.

Monoclonal antibodies to the P protein of Sendai virus define its structure and role in transcription.

A. Portner, K. Deshpande, A. Portneri, 1985, Virology.

Structural and functional analysis of Sendai virus nucleocapsid protein NP with monoclonal antibodies.

A. Portner, K. Deshpande, Kathryn L. Deshpande, 1984, Virology.

Synthesis of message and genome RNAs in vitro by Sendai virus-infected cell nucleocapsids.

A. Portner, 1982, The Journal of general virology.

The HN glycoprotein of Sendai virus: analysis of site(s) involved in hemagglutinating and neuraminidase activities.

A. Portner, 1981, Virology.

Inhibition of RNA synthesis following proteolytic cleavage of Newcastle disease virus P protein.

V. G. Chinchar, A. Portner, 1981, Virology.

Sendai Virion Transcriptase Complex: Polypeptide Composition and Inhibition by Virion Envelope Proteins

P. Marx, A. Portner, D. Kingsbury, 1974, Journal of virology.

A recent field isolate of Sendai virus has a temperature-sensitive HN glycoprotein.

A. Portner, W. Gorman, 1989, Virology.

Localization of functional sites on the hemagglutinin-neuraminidase glycoprotein of Sendai virus by sequence analysis of antigenic and temperature-sensitive mutants.

S. Thompson, A. Portner, Susan D. Thompson, 1987, Virology.

Safety and Immunogenicity of an Intranasal Sendai Virus-Based Human Parainﬂuenza Virus Type 1 Vaccine in 3- to 6-Year-Old Children

J. Allay, C. Russell, P. Freiden, 2015 .

Safety and Immunogenicity of an Intranasal Sendai Virus-Based Human Parainfluenza Virus Type 1 Vaccine in 3- to 6-Year-Old Children

J. Allay, C. Russell, P. Freiden, 2014, Clinical and Vaccine Immunology.

Homologous Interference by Incomplete Sendai Virus Particles: Changes in Virus-Specific Ribonucleic Acid Synthesis

A. Portner, D. Kingsbury, 1971, Journal of virology.

Crystals of hemagglutinin-neuraminidase of parainfluenza virus contain triple-stranded helices.

W. G. Laver, K. Murti, T. Takimoto, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Role of the Hemagglutinin-Neuraminidase Protein in the Mechanism of Paramyxovirus-Cell Membrane Fusion

S. Crennell, G. Taylor, H. Connaris, 2002, Journal of Virology.

Role of the Hemagglutinin-Neuraminidase Protein in the Mechanism of Paramyxovirus-Cell Membrane Fusion

S. Crennell, G. Taylor, H. Connaris, 2002, Journal of Virology.

W. J. Bean, R. Webster, A. Portner, 1980, Virology.

Sendai virus replication: an ultrastructural comparison of productive and abortive infections in avian cells.

A. Portner, R. Darlington, D. Kingsbury, 1970, The Journal of general virology.

Safety and immunogenicity of intranasal murine parainfluenza virus type 1 (Sendai virus) in healthy human adults.

J. Shenep, C. Coleclough, J. Hurwitz, 2004, Vaccine.

Measles Virus Ribonucleic Acid and Protein Synthesis: Effects of 6-Azauridine and Cycloheximide on Viral Replication

R. Bussell, A. Portner, 1973, Journal of virology.

Complementary RNAs in Paramyxovirions and Paramyxovirus-infected Cells

A. Portner, D. Kingsbury, 1970, Nature.

Elevated expression of the human parainfluenza virus type 1 F gene downregulates HN expression.

K. Murti, T. Takimoto, A. Portner, 1997, Virology.

Crystallization of biologically active hemagglutinin-neuraminidase glycoprotein dimers proteolytically cleaved from human parainfluenza virus type 1

W. G. Laver, K. Murti, T. Takimoto, 1992, Journal of Virology.

Location of amino acid residues important for the structure and biological function of the haemagglutinin-neuraminidase glycoprotein of Sendai virus by analysis of escape mutants.

A. Portner, D. Lyn, J. Nedrud, 1991, The Journal of general virology.

Structure, Function, and Intracellular Processing of the Glycoproteins of Paramyxoviridae

T. Morrison, A. Portner, 1991 .

Antibodies against Sendai virus L protein: distribution of the protein in nucleocapsids revealed by immunoelectron microscopy.

K. Murti, A. Portner, E. Morgan, 1988, Virology.

Association of nucleocapsid polypeptides with defective RNA synthesis in a temperature-sensitive mutant of Sendai virus.

A. Portner, 1977, Virology.

Human parainfluenza virus type 1 but not Sendai virus replicates in human respiratory cells despite IFN treatment.

T. Takimoto, A. Portner, T. Bousse, 2006, Virus research.

N-Linked Glycan at Residue 523 of Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Masks a Second Receptor-Binding Site

G. Taylor, V. Mishin, Makiko Watanabe, 2010, Journal of Virology.

Probing the Sialic Acid Binding Site of the Hemagglutinin-Neuraminidase of Newcastle Disease Virus: Identification of Key Amino Acids Involved in Cell Binding, Catalysis, and Fusion

S. Crennell, G. Taylor, R. Russell, 2002, Journal of Virology.

Restriction of cell surface expression of Sendai virus hemagglutinin-neuraminidase glycoprotein correlates with its higher instability in persistently and standard plus defective interfering virus infected BHK-21 cells.

L. Roux, P. Beffy, A. Portner, 1984, Virology.

Intranasal Sendai virus vaccine protects African green monkeys from infection with human parainfluenza virus-type one.

K. Soike, M. Sangster, C. Coleclough, 1997, Vaccine.

Antibody response in children to antigen sites on human PIV-3 HN: correlation with known epitopes mapped by monoclonal antibodies.

K. Henrickson, A. Portner, 1990, Vaccine.

Linked transcripts of the genes for leader and N message are synthesized in vitro by vesicular stomatitis virus.

V. G. Chinchar, A. Portner, L. Amesse, 1982, Biochemical and biophysical research communications.

CHAPTER 2 – VIRAL REPLICATION

A. Portner, C. Pridgen, 1975 .

Structural analysis of a designed inhibitor complexed with the hemagglutinin-neuraminidase of Newcastle disease virus

G. Taylor, J. C. Dyason, M. Itzstein, 2006, Glycoconjugate Journal.

Nucleocapsid Incorporation into Parainfluenza Virus Is Regulated by Specific Interaction with Matrix Protein

K. Murti, T. Takimoto, A. Portner, 2001, Journal of Virology.

The Sendai virus nucleocapsid exists in at least four different helical states

E. Egelman, G. Murti, A. Portner, 1989, Journal of virology.

Two regions of the P protein are required to be active with the L protein for human parainfluenza virus type 1 RNA polymerase activity.

T. Matrosovich, T. Takimoto, A. Portner, 2001, Virology.

Molecular cloning and expression of human parainfluenza virus type 1 L gene.

T. Takimoto, A. Portner, T. Bousse, 2000, Virus research.

The Long Noncoding Region of the Human Parainfluenza Virus Type 1 F Gene Contributes to the Read-Through Transcription at the M-F Gene Junction

Y. Nagai, A. Kato, T. Matrosovich, 2002, Journal of Virology.

Respiratory syncytial virus (RSV) fusion protein expressed by recombinant Sendai virus elicits B-cell and T-cell responses in cotton rats and confers protection against RSV subtypes A and B.

K. Boyd, S. Krishnamurthy, S. Surman, 2007, Vaccine.

Virus-specific CD8+ T-cell memory determined by clonal burst size

Peter C. Doherty, P. Doherty, L. Hyland, 1994, Nature.

Human parainfluenza virus type 1 evolution combines cocirculation of strains and development of geographically restricted lineages.

S. Hetherington, A. Portner, R. Scroggs, 1994, The Journal of infectious diseases.

Residues in the Heptad Repeat A Region of the Fusion Protein Modulate the Virulence of Sendai Virus in Mice

K. Boyd, C. Russell, Olga A. Bridges, 2009, Journal of Virology.

Effect of Hemagglutinin-Neuraminidase Inhibitors BCX 2798 and BCX 2855 on Growth and Pathogenicity of Sendai/Human Parainfluenza Type 3 Chimera Virus in Mice

Scott A. Brown, G. Taylor, K. Boyd, 2009, Antimicrobial Agents and Chemotherapy.

Parainfluenza Viruses of Humans

E. Adderson, A. Portner, 2008 .

Recombinant Sendai virus as a novel vaccine candidate for respiratory syncytial virus.

K. Boyd, S. Krishnamurthy, C. Coleclough, 2005, Viral immunology.

Molecular mechanism of paramyxovirus budding.

T. Takimoto, A. Portner, 2004, Virus research.

Biological Significance of the Second Receptor Binding Site of Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein

G. Taylor, S. Krishnamurthy, S. Samal, 2004, Journal of Virology.

Second Sialic Acid Binding Site in Newcastle Disease Virus Hemagglutinin-Neuraminidase: Implications for Fusion

G. Taylor, M. Kiefel, M. von Itzstein, 2004, Journal of Virology.

Human Parainfluenza Virus Type 1 Matrix and Nucleoprotein Genes Transiently Expressed in Mammalian Cells Induce the Release of Virus-Like Particles Containing Nucleocapsid-Like Structures

K. Murti, T. Takimoto, A. Portner, 1999, Journal of Virology.

The M2 Ectodomain Is Important for Its Incorporation into Influenza A Virions

Y. Kawaoka, M. Castrucci, A. Portner, 1998, Journal of Virology.

Sendai virus-based RSV vaccine protects African green monkeys from RSV infection.

R. Rudraraju, J. Hurwitz, B. Jones, 2012, Vaccine.

Neutralizing epitopes of human parainfluenza virus type 3 are conformational and cannot be imitated by synthetic peptides.

C. Naeve, K. Henrickson, A. Portner, 1991, Vaccine.

An alternative route of infection for viruses: entry by means of the asialoglycoprotein receptor of a Sendai virus mutant lacking its attachment protein.

A. Schwartz, A. Portner, M. Markwell, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Safety and immunogenicity of an intranasal sendai virus-based vaccine for human parainfluenza virus type I and respiratory syncytial virus (SeVRSV) in adults

D. Bernstein, C. Russell, Mat Makowski, 2020, Human vaccines & immunotherapeutics.

Separate domains of Sendai virus P protein are required for binding to viral nucleocapsids.

A. Portner, K. Ryan, 1990, Virology.

Localization and characterization of Sendai virus nonstructural C and C' proteins by antibodies against synthetic peptides.

J. Seyer, K. Gupta, E. Beachey, 1986, Virus research.

Topography of a flexible ribonucleoprotein helix: protein-protein contacts in Sendai virus nucleocapsids

R. Raghow, A. Portner, D. Kingsbury, 1979, Journal of virology.

Development of Sendai virus-based vaccines to prevent pediatric respiratory virus infections

C. Russell, J. Shenep, J. Hurwitz, 2009 .

Inter- and Intra-Patient Sequence Diversity Among Parainfluenza Virus-Type 1 Nucleoprotein Genes

S. Hetherington, J. Hurwitz, A. Portner, 1997, Virus Genes.

Comparison of IgA versus IgG monoclonal antibodies for passive immunization of the murine respiratory tract.

A. Portner, D. Lyn, M. Lamm, 1992, Virus research.

Molecular evolution of the F glycoprotein of human parainfluenza virus type 1.

S. Hetherington, A. Portner, R. Scroggs, 1995, The Journal of infectious diseases.

Neuraminidase inhibitors as antiviral agents.

G. Taylor, A. Portner, I V Alymova, 2005, Current drug targets. Infectious disorders.

Synthesis of Sendai virus polypeptides by a cell-free extract from wheat germ.

J. Davies, A. Portner, D. Kingsbury, 1976, The Journal of general virology.

Sendai virus recombinant vaccine expressing hPIV-3 HN or F elicits protective immunity and combines with a second recombinant to prevent hPIV-1, hPIV-3 and RSV infections.

S. Krishnamurthy, C. Russell, Laura E Luque, 2008, Vaccine.

Viral cross-reactivity and antigenic determinants recognized by human parainfluenza virus type 1-specific cytotoxic T-cells.

U. Power, J. Hurwitz, T. Takimoto, 1994, Virology.

A single amino acid changes enhances the fusion promotion activity of human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein.

T. Takimoto, A. Portner, T. Bousse, 1995, Virology.

Expression of cDNA encoding the Sendai virus hemagglutinin-neuraminidase gene: characterization of wild-type and mutant gene products.

A. Portner, K. Ryan, T. Takahashi, 1992, Virology.