D. Yaffe

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Human Muscle Progenitor Cells Overexpressing Neurotrophic Factors Improve Neuronal Regeneration in a Sciatic Nerve Injury Mouse Model

D. Offen, T. Ben-Zur, R. Guy, 2019, Front. Neurosci..

Muscle-specific activation of a methylated chimeric actin gene

H. Cedar, R. Adelstein, U. Nudel, 1986, Cell.

The correlation between the synthesis of skeletal muscle actin, myosin heavy chain, and myosin light chain and the accumulation of corresponding mRNA sequences during myogenesis.

M. Shani, U. Nudel, D. Yaffe, 1981, Developmental biology.

The methylation state of 2 muscle-specific genes: restriction enzyme analysis did not detect a correlation with expression.

M. Shani, D. Yaffe, S. Admon, 1984, Nucleic acids research.

A deficit of brain dystrophin 71 impairs hypothalamic osmostat

A. Sène, D. Mornet, D. Yaffe, 2010, Journal of neuroscience research.

A 71-kilodalton protein is a major product of the Duchenne muscular dystrophy gene in brain and other nonmuscle tissues.

Z. Levy, G. Morris, U. Nudel, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Ectopic Muscle Expression of Neurotrophic Factors Improves Recovery After Nerve Injury

D. Offen, T. Ben-Zur, Y. Barhum, 2015, Journal of Molecular Neuroscience.

Transplanted Modified Muscle Progenitor Cells Expressing a Mixture of Neurotrophic Factors Delay Disease Onset and Enhance Survival in the SOD1 Mouse Model of ALS

E. Perlson, D. Offen, T. Ben-Zur, 2015, Journal of Molecular Neuroscience.

Therapeutic Effect of Myogenic Cells Modified to Express Neurotrophic Factors in a Rat Model of Sciatic Nerve Injury

E. Melamed, D. Offen, T. Ben-Zur, 2012, Journal of stem cells & regenerative medicine.

The in vitro cultivation and differentiation capacities of myogenic cell lines.

D. Yaffe, C. Richler, David Yaffe, 1970, Developmental biology.

Alterations of enzymatic activities during muscle differentiation in vitro.

G. Yagil, D. Yaffe, A. Shainberg, 1971, Developmental biology.

Synthesis of myosin light chains and accumulation of translatable mRNA coding for light chain-like polypeptides in differentiating muscle cultures.

D. Yaffe, Z. Yablonka, 1977, Differentiation; research in biological diversity.

Research group on neuromuscular diseases A report on various aspects of myogenic cell culture with particular reference to studies on the muscular dystrophies

D. Yaffe, H. Holtzer, K. W. Jones, 1975, Journal of the Neurological Sciences.

Skeletal muscle actin mRNA. Characterization of the 3' untranslated region.

D. Givol, A. Frischauf, M. Shani, 1981, Nucleic acids research.

Expression of the genes coding for the skeletal muscle and cardiac actions in the heart.

H. Czosnek, U. Nudel, D. Yaffe, 1984, Nucleic acids research.

Retention of differentiation potentialities during prolonged cultivation of myogenic cells.

D. Yaffe, 1968, Proceedings of the National Academy of Sciences of the United States of America.

THE FORMATION OF HYBRID MULTINUCLEATED MUSCLE FIBERS FROM MYOBLASTS OF DIFFERENT GENETIC ORIGIN.

D. Yaffe, M. Feldman, 1965, Developmental biology.

Organization of Muscle-Specific Genes in the Rodent Genome

F. Ruddle, H. Czosnek, P. Barker, 1983 .

Developmental changes preceding cell fusion during muscle differentiation in vitro.

D. Yaffe, David Yaffe, 1971, Experimental cell research.

Construction of recombinant plasmids containing rat muscle actin and myosin light chain DNA sequences.

H. Lehrach, A. Frischauf, M. Shani, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Isolation and characterization of rat skeletal muscle and cytoplasmic actin genes.

H. Czosnek, M. Shani, U. Nudel, 1982, Proceedings of the National Academy of Sciences of the United States of America.

The genes coding for the muscle contractile proteins, myosin heavy chain, myosin light chain 2, and skeletal muscle actin are located on three different mouse chromosomes.

F. Ruddle, H. Czosnek, P. Barker, 1982, The EMBO journal.

Identification of recombinant phages containing sequences from different rat myosin heavy chain genes.

Y. Shaul, M. Shani, U. Nudel, 1980, Nucleic acids research.

Expression of the putative Duchenne muscular dystrophy gene in differentiated myogenic cell cultures and in the brain

K. Robzyk, U. Nudel, D. Yaffe, 1988, Nature.

Kir4.1 and AQP4 associate with Dp71‐ and utrophin‐DAPs complexes in specific and defined microdomains of Müller retinal glial cell membrane

J. Sahel, P. Fort, A. Reichenbach, 2008, Glia.

Role of Mental Retardation-Associated Dystrophin-Gene Product Dp71 in Excitatory Synapse Organization, Synaptic Plasticity and Behavioral Functions

J. Billard, D. Jaillard, S. Laroche, 2009, PloS one.

Multinucleated Muscle Fibres: Induction of DNA Synthesis and Mitosis by Polyoma Virus Infection

D. Gershon, D. Yaffe, 1967, Nature.

Gene Expression during Differentiation of Contractile Muscle Fibers

D. Yaffe, H. Dym, 1973 .

Autoradiographic study of the incorporation of uridine-3H during myogenesis in tissue culture.

D. Yaffe, S. Fuchs, 1967, Developmental biology.

SV40 immortalizes myogenic cells: DNA synthesis and mitosis in differentiating myotubes.

U. Nudel, D. Yaffe, O. Fuchs, 1990, Differentiation; research in biological diversity.

Mapping of dystrophin brain promoter: A deletion of this region is compatible with normal intellect

G. V. Ommen, J. D. Dunnen, B. Bakker, 1991, Neuromuscular Disorders.

Myoblast transplantations lead to the expression of the laminin α2 chain in normal and dystrophic (dy/dy) mouse muscles

J. Puymirat, M. Fiszman, M. Fardeau, 1999, Gene Therapy.

The Cellular Prion Protein Colocalizes with the Dystroglycan Complex in the Brain

R. Gabizon, G. Keshet, U. Nudel, 2000, Journal of neurochemistry.

Control of myogenesis in vitro by Ca 2 + concentration in nutritional medium.

G. Yagil, D. Yaffe, A. Shainberg, 1969, Experimental cell research.

Jordans' anomaly in white blood cells. Report of case.

D. Yaffe, L. Rozenszajn, P. Efrati, 1966, Blood.

Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy

A. S. Yatsenko, D. Baker, H. Ruohola-Baker, 2007, The EMBO journal.

A deletion including the brain promoter of the Duchenne muscular dystrophy gene is not associated with mental retardation

M. Passos-Bueno, M. Zatz, M. Vainzof, 1992, Neuromuscular Disorders.

Multiple products of the Duchenne muscular dystrophy gene.

S. Bar, U. Nudel, D. Rapaport, 1992, Symposia of the Society for Experimental Biology.

A novel product of the Duchenne muscular dystrophy gene which greatly differs from the known isoforms in its structure and tissue distribution.

S. Bar, Z. Levy, U. Nudel, 1990, The Biochemical journal.

Developmentally regulated expression of a chicken muscle-specific gene in stably transfected rat myogenic cells.

C. Ordahl, U. Nudel, D. Yaffe, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

D. Yaffe, O. Saxel, DAVID YAFFE, 1977, Nature.

Cellular aspects of muscle differentiation in vitro.

D. Yaffe, David Yaffe, 1969, Current topics in developmental biology.

Functional Implication of Dp71 in Osmoregulation and Vascular Permeability of the Retina

J. Sahel, A. Reichenbach, A. Wurm, 2009, PloS one.

Synthesis of tropomyosin in myogenic cultures and in RNA-directed cell-free systems: Qualitative changes in the polypeptides

D. Yaffe, Y. Carmon, S. Neuman, 1978, Cell.

Developmentally regulated expression of chimeric genes containing muscle actin DNA sequences in transfected myogenic cells.

U. Nudel, D. Yaffe, D. Melloul, 1984, The EMBO journal.

Creatine kinase isoenzyme transition in actinomycin D-treated differentiating muscle cultures.

H. Eppenberger, D. Turner, D. Yaffe, 1978, Experimental cell research.

CYTOTOXIC EFFECT OF MACROPHAGES FROM MYASTHENIC ANIMALS ON MUSCLE CELLS IN CULTURE

S. Fuchs, D. Yaffe, R. Tarrab‐Hazdai, 1979 .

Immunogenetic studies on x-irradiated mice treated with hematopoietic cells and grafted with tumor tissues.

D. Yaffe, M. Feldman, 1959, Journal of the National Cancer Institute.

The distribution and in vitro propagation of an agent causing high plasma lactic dehydrogenase activity.

D. Yaffe, 1962, Cancer research.

Regulatory mechanisms controlling the stability of cell differentiation.

M. Feldman, D. Yaffe, I. Bleiberg, 1966, Cancer research.

Determination of actin messenger RNA in cultures of differentiating embryonic chick skeletal muscle.

B. Paterson, D. Yaffe, B. Roberts, 1974, Proceedings of the National Academy of Sciences of the United States of America.

IMMUNOLOGICAL PROPERTIES OF CHEMICALLY INDUCED SARCOMAS.

A. Globerson, D. Yaffe, M. Feldman, 1963, Philippine journal of cancer.

THE EFFECT OF ACTINOMYCIN D ON HEART AND THIGH MUSCLE CELLS GROWN IN VITRO.

D. Yaffe, M. Feldman, Michael Feldman, 1964, Developmental biology.

The nucleotide sequence of the rat cytoplasmic β–actin gene

M. Shani, Z. Levy, U. Nudel, 1983 .

The nucleotide sequence of the rat cytoplasmic beta-actin gene.

M. Shani, Z. Levy, U. Nudel, 1983, Nucleic acids research.

The reversible inhibition of myoblast fusion by ethidium bromide (EB).

C. Brunk, D. Yaffe, 1976, Experimental cell research.

Ectopic Muscle Expression of Neurotrophic Factors Improves Recovery After Nerve Injury

D. Offen, Y. Barhum, D. Yaffe, 2015, Journal of Molecular Neuroscience.

Highly conserved sequences in the 3' untranslated region of mRNAs coding for homologous proteins in distantly related species.

U. Nudel, D. Yaffe, S. Neuman, 1985, Nucleic acids research.

Regulated expression of muscle-specific genes introduced into mouse embryonal stem cells: inverse correlation with DNA methylation.

M. Shani, D. Yaffe, D. Shinar, 1989, Differentiation; research in biological diversity.

Nucleotide sequence of the rat skeletal muscle actin gene

D. Givol, M. Shani, U. Nudel, 1982, Nature.

Regeneration and Transdifferentiation Potential of Muscle‐Derived Stem Cells Propagated as Myospheres

R. Sarig, U. Nudel, D. Yaffe, 2006, Stem cells.

Cytochemical and genetic studies in four cases of Chediak-Higashi-Steinbrinck syndrome.

D. Yaffe, L. Rozenszajn, P. Efrati, 1965, Acta haematologica.

Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype

K. Ocorr, R. Bodmer, T. Akasaka, 2008, Aging cell.

Targeted inactivation of dystrophin gene product Dp71: phenotypic impact in mouse retina.

J. Sahel, P. Fort, A. Reichenbach, 2003, Human molecular genetics.

Duchenne muscular dystrophy gene product is not identical in muscle and brain

P. Einat, Z. Levy, U. Nudel, 1989, Nature.

Detection of Duchenne muscular dystrophy gene products in amniotic fluid and chorionic villus sampling cells

M. Brusel, U. Nudel, D. Yaffe, 1993 .

A housekeeping type promoter, located in the 3' region of the Duchenne muscular dystrophy gene, controls the expression of Dp71, a major product of the gene.

U. Nudel, D. Yaffe, D. Lederfein, 1993, Human molecular genetics.

Dystrophin Dp71 Expression Is Down-regulated during Myogenesis

P. Gómez, B. Cisneros, F. Recillas-Targa, 2005, Journal of Biological Chemistry.

Targeted inactivation of Dp71, the major non-muscle product of the DMD gene: differential activity of the Dp71 promoter during development.

R. Sarig, I. Gitelman, U. Nudel, 1999, Human molecular genetics.

Reduced levels of dystrophin associated proteins in the brains of mice deficient for Dp71.

Z. Levy, U. Nudel, D. Yaffe, 1996, Human molecular genetics.

Exogenous Dp71 restores the levels of dystrophin associated proteins but does not alleviate muscle damage in mdx mice

K. Campbell, Y. Sunada, U. Nudel, 1994, Nature Genetics.

The amount of the endogenous and exogenous skeletal muscle actin mRNA in the heart of transgenic mice is affected by the genotype of the cardiac actin gene.

P. Einat, M. Shani, D. Yaffe, 1990, Differentiation; research in biological diversity.

Brain-type and muscle-type promoters of the dystrophin gene differ greatly in structure

U. Nudel, D. Yaffe, A. Makover, 1991, Neuromuscular Disorders.

Expression of Cloned Muscle-Specific Genes in Transfected Cells and Transgenic Mice

M. Shani, U. Nudel, D. Yaffe, 1986 .

Expression in transgenic mice of two genes of different tissue specificity integrated into a single chromosomal site.

P. Einat, Y. Bergman, M. Shani, 1987, Genes & development.

The genes coding for the cardiac muscle actin, the skeletal muscle actin and the cytoplasmic beta‐actin are located on three different mouse chromosomes.

F. Ruddle, H. Czosnek, P. Barker, 1983, The EMBO journal.

DNAase I sensitivity of genes expressed during myogenesis.

H. Czosnek, M. Shani, U. Nudel, 1982, Nucleic acids research.

A myogenic cell line with altered serum requirements for differentiation.

D. Yaffe, O. Saxel, David Yaffe, 1977, Differentiation; research in biological diversity.

Immunogenetic changes induced in tumors grown in radiation chimeras.

D. Yaffe, M. Feldman, 1959, Journal of the National Cancer Institute.

Production of Organ-Specific Antibodies following an Induction of Tolerance to Antigens of Heterologous Organs

D. Yaffe, M. Feldman, 1957, Nature.

Exogenous Dp71 is a dominant negative competitor of dystrophin in skeletal muscle

A. Meshorer, H. Jockusch, U. Nudel, 2002, Neuromuscular Disorders.

The dystrophin / utrophin homologues in Drosophila and in sea urchin.

U. Nudel, D. Yaffe, S. Neuman, 2001, Gene.

A sea urchin gene encoding dystrophin-related proteins.

J. M. Venuti, A. Pansky, U. Nudel, 1998, Human molecular genetics.

Characterization and cell type distribution of a novel, major transcript of the Duchenne muscular dystrophy gene.

J. D. den Dunnen, G. V. van Ommen, G. van Ommen, 1992, Differentiation; research in biological diversity.

Specificity of expression of the muscle and brain dystrophin gene promoters in muscle and brain cells

U. Nudel, D. Yaffe, R. Simantov, 1990, Neuron.

The Drosophila homologue of the dystrophin gene – Introns containing promoters are the major contributors to the large size of the gene

U. Nudel, D. Yaffe, S. Neuman, 2005, FEBS letters.

Cloned Myogenic Cells Can Transdifferentiate In Vivo into Neuron-Like Cells

R. Sarig, U. Nudel, A. Panski, 2010, PloS one.

Transplanted myogenic progenitor cells express neuronal markers in the CNS and ameliorate disease in Experimental Autoimmune Encephalomyelitis

R. Sarig, R. Arnon, R. Aharoni, 2009, Journal of Neuroimmunology.

Expression of the Duchenne muscular dystrophy gene products in embryonic stem cells and their differentiated derivatives.

U. Nudel, D. Rapaport, D. Yaffe, 1992, The Journal of biological chemistry.

Snythesis of polypeptides with the properties of myosin light chains direct by RNA extracted from muscle cultures.

D. Yaffe, Z. Yablonka, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Expression of creatine kinase isoenzymes in myogenic cell lines.

D. Yaffe, H. Dym, 1979, Developmental biology.

Ultrastructural probing of β‐adrenoreceptors on cell surfaces

D. Atlas, D. Yaffe, E. Skutelsky, 1978 .

The capacity of polyadenylated RNA from myogenic cells treated with actinomycin D to direct protein synthesis in a cell-free system.

R. Singer, D. Yaffe, G. Kessler-Icekson, 1978, European journal of biochemistry.

Accumulation of muscle-specific RNA sequences during myogenesis.

D. Yaffe, D. Zevin-Sonkin, 1980, Developmental biology.

Transplanted Modified Muscle Progenitor Cells Expressing a Mixture of Neurotrophic Factors Delay Disease Onset and Enhance Survival in the SOD1 Mouse Model of ALS

E. Perlson, D. Offen, Y. Barhum, 2015, Journal of Molecular Neuroscience.

Immunogenetic studies on x-irradiated mice treated with homologous hematopoietic cells.

D. Yaffe, M. Feldman, 1958, Journal of the National Cancer Institute.

Dp71, the nonmuscle product of the Duchenne muscular dystrophy gene is associated with the cell membrane

U. Nudel, D. Rapaport, D. Yaffe, 1993, FEBS letters.