P. V. Shcherbakova

发表

Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae

Daniel P. Kane, Stephanie R. Barbari, Elizabeth A. Moore, 2018, G3: Genes, Genomes, Genetics.

DNA Binding Properties of the Yeast Msh2-Msh6 and Mlh1-Pms1 Heterodimers

T. Kunkel, D. Erie, E. Kool, 2002, Biological chemistry.

In Vivo Consequences of Putative Active Site Mutations in Yeast DNA Polymerases α, ε, δ, and ζ

T. Kunkel, P. V. Shcherbakova, Y. Pavlov, 2001 .

Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ϵ variants at low dNTP levels

Joel Markgren, E. Johansson, Stephanie R. Barbari, 2022, Nucleic acids research.

DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair.

T. Kunkel, K. Tomer, C. Borchers, 2003, Nucleic acids research.

DNA Polymerase ζ-Dependent Lesion Bypass in Saccharomyces cerevisiae Is Accompanied by Error-Prone Copying of Long Stretches of Adjacent DNA

Tony M Mertz, P. V. Shcherbakova, Danielle L. Daee, 2015, PLoS genetics.

DNA polymerases at the eukaryotic fork-20 years later.

P. V. Shcherbakova, Y. Pavlov, 2010, Mutation research.

A novel function of DNA polymerase ζ regulated by PCNA

P. Burgers, P. V. Shcherbakova, Matthew R. Northam, 2006 .

Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28 gene

I. Rogozin, R. Fedorov, E. Tarakhovskaya, 2020, bioRxiv.

In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta.

T. Kunkel, P. V. Shcherbakova, Y. Pavlov, 2001, Genetics.

Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations

A. Chabes, P. Burgers, P. V. Shcherbakova, 2016, Nucleic acids research.

Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations.

A. Chabes, P. Burgers, P. V. Shcherbakova, 2016, Nucleic acids research.

The Non-canonical Protein Binding Site at the Monomer-Monomer Interface of Yeast Proliferating Cell Nuclear Antigen (PCNA) Regulates the Rev1-PCNA Interaction and Polζ/Rev1-dependent Translesion DNA Synthesis*

Neeru M. Sharma, P. V. Shcherbakova, O. V. Kochenova, 2011, The Journal of Biological Chemistry.

Translesion synthesis DNA polymerases and control of genome stability.

I. Fijalkowska, P. V. Shcherbakova, 2006, Frontiers in bioscience : a journal and virtual library.

Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase ε

S. C. Kamerlin, E. Johansson, P. V. Shcherbakova, 2019, Nature Communications.

Multiple antimutagenesis mechanisms affect mutagenic activity and specificity of the base analog 6-N-hydroxylaminopurine in bacteria and yeast.

V. Noskov, K. Makarova, R. Schaaper, 1998, Mutation research.

A Reversible Histone H3 Acetylation Cooperates with Mismatch Repair and Replicative Polymerases in Maintaining Genome Stability

F. Kadyrov, Tony M Mertz, Yu Zhang, 2013, PLoS genetics.

A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotype, indicating fidelity defects distinct from loss of proofreading.

Daniel P. Kane, P. V. Shcherbakova, 2014, Cancer research.

Roles of DNA polymerases in replication, repair, and recombination in eukaryotes.

I. Rogozin, P. V. Shcherbakova, Y. Pavlov, 2006, International review of cytology.

Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for therapy.

Stephanie R. Barbari, P. V. Shcherbakova, 2017, DNA repair.

DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures

Sara K. Binz, P. Burgers, Tony M Mertz, 2013, Nucleic acids research.

MLH1 mutations differentially affect meiotic functions in Saccharomyces cerevisiae.

T. Kunkel, E. Hoffmann, P. V. Shcherbakova, 2003, Genetics.

Differential ATP Binding and Intrinsic ATP Hydrolysis by Amino-terminal Domains of the Yeast Mlh1 and Pms1 Proteins*

T. Kunkel, M. Hall, Mark C Hall, 2002, The Journal of Biological Chemistry.

Inactivation of DNA Mismatch Repair by Increased Expression of Yeast MLH1

Pierre R. Bushel, Cynthia A. Afshari, Thomas A. Kunkel, 2001, Molecular and Cellular Biology.

Mutator Phenotypes Conferred by MLH1Overexpression and by Heterozygosity for mlh1Mutations

T. Kunkel, P. V. Shcherbakova, 1999, Molecular and Cellular Biology.

Base analog N6-hydroxylaminopurine mutagenesis in Escherichia coli: genetic control and molecular specificity.

T. Kunkel, R. Schaaper, A. Matsuda, 1996, Mutation research.

3' -> 5' Exonucleases of DNA Polymerases ε and δ Correct Base Analog Induced DNA Replication Errors on opposite DNA Strands in Saccharomyces Cerevisiae

P. V. Shcherbakova, Y. Pavlov, 1996 .

3'-->5' exonucleases of DNA polymerases epsilon and delta correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae.

P. V. Shcherbakova, Y. Pavlov, 1996, Genetics.

HAM1, the gene controlling 6‐N‐hydroxylaminopurine sensitivity and mutagenesis in the yeast Saccharomyces cerevisiae

V. Noskov, H. Hayatsu, K. Negishi, 1996, Yeast.

Participation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in yeast Saccharomyces cerevisiae

P. V. Shcherbakova, S. Inge-Vechtomov, E. Stepchenkova, 2011, Biochemistry (Moscow).

Participation of DNA Polymerase ζ in Replication of Undamaged DNA in Saccharomyces cerevisiae

Heather A. Robinson, P. V. Shcherbakova, Matthew R. Northam, 2010, Genetics.

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme

Sushma Sharma, A. Chabes, Daniel P. Kane, 2019, Nature Communications.

Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polymerase δ mutation in human cells

T. Tahirov, Tony M Mertz, P. V. Shcherbakova, 2017, Oncogene.

CTG-19-0397 1..9

V. Deshpande, Stephanie R. Barbari, P. V. Shcherbakova, 2022 .

Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorectal and Endometrial Tumors

V. Deshpande, Stephanie R. Barbari, P. V. Shcherbakova, 2020, Clinical and translational gastroenterology.

Unique Error Signature of the Four-subunit Yeast DNA Polymerase ϵ*

T. Kunkel, I. Rogozin, E. Johansson, 2003, Journal of Biological Chemistry.

Functions of eukaryotic DNA polymerases.

T. Kunkel, K. Bebenek, P. V. Shcherbakova, 2003, Science of aging knowledge environment : SAGE KE.

Base analog 6-N-hydroxylaminopurine mutagenesis in the yeast Saccharomyces cerevisiae is controlled by replicative DNA polymerases.

V. Noskov, P. V. Shcherbakova, Y. Pavlov, 1996, Mutation research.

Mismatch repair and DNA polymerase δ proofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ϵ variant

P. V. Shcherbakova, Xuanxuan Xing, Chelsea R. Bulock, 2020, Nucleic acids research.

A cancer-associated DNA polymerase δ variant modeled in yeast causes a catastrophic increase in genomic instability

Tony M Mertz, P. V. Shcherbakova, Danielle L Daee, 2009, Proceedings of the National Academy of Sciences.

Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase ε

Shina Caroline Lynn Kamerlin, E. Johansson, P. V. Shcherbakova, 2019, Nature Communications.

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme

Sushma Sharma, A. Chabes, Daniel P. Kane, 2019, Nature Communications.

Role of DNA polymerases in repeat-mediated genome instability.

S. Mirkin, Alexander A. Shishkin, I. Voineagu, 2012, Cell reports.

Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity

Sushma Sharma, A. Chabes, Tony M Mertz, 2015, Proceedings of the National Academy of Sciences.

DNA polymerase δ proofreads errors made by DNA polymerase ε

P. V. Shcherbakova, Xuanxuan Xing, Chelsea R. Bulock, 2020, Proceedings of the National Academy of Sciences.

Mutagenic specificity of the base analog 6-N-hydroxylaminopurine in the URA3 gene of the yeast Saccharomyces cerevisiae.

P. V. Shcherbakova, Y. Pavlov, 1993, Mutagenesis.

A novel function of DNA polymerase zeta regulated by PCNA.

P. Burgers, P. V. Shcherbakova, Matthew R. Northam, 2006, The EMBO journal.

Mutator phenotype due to loss of heterozygosity in diploid yeast strains with mutations in MSH2 and MLH1.

T. Kunkel, P. V. Shcherbakova, K. Drotschmann, 2000, Toxicology letters.

HAM1, the gene controlling 6‐N‐hydroxylaminopurine sensitivity and mutagenesis in the yeast Saccharomyces cerevisiae

V. Noskov, S. Kozmin, H. Hayatsu, 1996, Yeast.

DNA Binding Properties of the Yeast Msh 2-Msh 6 and Mlh 1-Pms 1 Heterodimers

T. Kunkel, Hong Wang, D. Erie, 2004 .

Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity

Sushma Sharma, A. Chabes, Tony M Mertz, 2015, Proceedings of the National Academy of Sciences.

Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28.

Stephanie R. Barbari, P. V. Shcherbakova, Y. Pavlov, 2021, Genetics.

A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotype, indicating fidelity defects distinct from loss of proofreading.

Daniel P. Kane, P. V. Shcherbakova, 2014, Cancer research.