S. Rowlinson

发表

34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019): part 2

C. Daige, J. Wiggins, Giulia Agnello, 2019, Journal of Immunotherapy for Cancer.

Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant

M. Todaro, G. Stassi, F. Giuliante, 2019, Oncogene.

A Growth Hormone Agonist Produced by Targeted Mutagenesis at Binding Site 1.

M. Waters, A. Robins, R. Brinkworth, 1995, The Journal of Biological Chemistry.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Manish R. Patel, Charles J. Vaske, Joe Y. Chang, 2016, Journal for Immunotherapy of Cancer.

Arachidonic Acid Oxygenation by COX-1 and COX-2

L. Marnett, A. Kalgutkar, D. Goodwin, 1999, The Journal of Biological Chemistry.

Control of Prostaglandin Stereochemistry at the 15-Carbon by Cyclooxygenases-1 and -2

L. Marnett, A. Brash, S. Rowlinson, 2002, The Journal of Biological Chemistry.

Recombinant expression of Munc18c in a baculovirus system and interaction with syntaxin4.

D. James, Jennifer L. Martin, C. Gee, 2003, Protein expression and purification.

Evidence for involvement of the carboxy terminus of helix 1 of growth hormone in receptor binding: use of charge reversal mutagenesis to account for calcium dependence of binding and for design of higher affinity analogues.

M. Waters, A. Robins, Carolyn R. Senn, 1994, Biochemistry.

Oxygenation of the Endocannabinoid, 2-Arachidonylglycerol, to Glyceryl Prostaglandins by Cyclooxygenase-2*

L. Marnett, K. Kozak, S. Rowlinson, 2000, The Journal of Biological Chemistry.

Biochemistry and Cellular Distribution of the Growth Hormone Receptor

M. Waters, W. Young, G. Muscat, 1993 .

Amino Acid Determinants in Cyclooxygenase-2 Oxygenation of the Endocannabinoid 2-Arachidonylglycerol*

L. Marnett, K. Kozak, S. Rowlinson, 2001, The Journal of Biological Chemistry.

Signal Transduction by the Growth Hormone Receptor

C. Wells, M. Waters, G. Muscat, 1994, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Spatial Requirements for 15-(R)-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid Synthesis within the Cyclooxygenase Active Site of Murine COX-2

L. Marnett, J. Gierse, D. Goodwin, 2000, The Journal of Biological Chemistry.

Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid anandamide.

L. Marnett, K. Kozak, S. Rowlinson, 2003, Biochemistry.

Arginine depletion as a therapeutic approach for patients with COVID-19

R. Carvajal, Shaheer Khan, S. Rowlinson, 2020, International Journal of Infectious Diseases.

Fluorescence quenching analysis of the association and dissociation of a diarylheterocycle to cyclooxygenase-1 and cyclooxygenase-2: dynamic basis of cyclooxygenase-2 selectivity.

L. Marnett, J. Sutin, J. Talley, 2000, Biochemistry.

Substitution of tyrosine for the proximal histidine ligand to the heme of prostaglandin endoperoxide synthase 2: implications for the mechanism of cyclooxygenase activation and catalysis.

L. Marnett, D. Goodwin, S. Rowlinson, 2000, Biochemistry.

A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385*

Lawrence J Marnett, James R Kiefer, R. Kurumbail, 2003, Journal of Biological Chemistry.

Aspirin-like molecules that covalently inactivate cyclooxygenase-2.

L. Marnett, A. Kalgutkar, K. Seibert, 1998, Science.

Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors.

L. Marnett, A. Kalgutkar, K. Kozak, 2000, Proceedings of the National Academy of Sciences of the United States of America.

5.10 – Structure, Function, and Inhibition of Prostaglandin Endoperoxide Synthases

L. Marnett, A. Kalgutkar, D. Goodwin, 1999 .

Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors.

Lawrence J Marnett, L. Marnett, A. Kalgutkar, 2002, Bioorganic & medicinal chemistry letters.

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

G. Georgiou, Peng Huang, M. Keating, 2016, Nature Medicine.

Engineering of the Recombinant Expression and PEGylation Efficiency of the Therapeutic Enzyme Human Thymidine Phosphorylase

Giulia Agnello, S. Rowlinson, Catrina M. Somody, 2021, Frontiers in Bioengineering and Biotechnology.

Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.

G. Georgiou, L. Burrage, Brendan H. Lee, 2015, Human molecular genetics.

Knockdown of Cancer Testis Antigens Modulates Neural Stem Cell Marker Expression in Glioblastoma Tumor Stem Cells

Jonathan Low, L. Ricci-Vitiani, R. Pallini, 2010, Journal of biomolecular screening.

Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine

O. Pardo, M. Seckl, Christiaan F. Labuschagne, 2017, Cell reports.

A BMP7 variant inhibits the tumorigenic potential of glioblastoma stem-like cells

L. Ricci-Vitiani, R. Pallini, L. Larocca, 2012, Cell Death and Differentiation.

Systemic depletion of serum l-Cyst(e)ine with an engineered human enzyme induces production of reactive oxygen species and suppresses tumor growth in mice

G. Georgiou, Peng Huang, M. Keating, 2016, Nature medicine.

Large-scale preparation and characterization of recombinant ovine placental lactogen.

A. Kantor, J. Grosclaude, C. Nespoulous, 1997, The Journal of endocrinology.

An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway

M. Waters, J. Hancock, J. Barclay, 2008, Nature Cell Biology.

Activation of Chimeric and Full-length Growth Hormone Receptors by Growth Hormone Receptor Monoclonal Antibodies

M. Waters, C. Strasburger, Zida Wu, 1998, The Journal of Biological Chemistry.

and in vivo by IL-20 Selective enhancement of multipotential hematopoietic progenitors in vitro

Dan Liu, D. Witcher, V. Wroblewski, 2013 .

Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20.

H. Broxmeyer, D. Witcher, V. Wroblewski, 2003, Blood.

Arginase Therapy Combines Effectively with Immune Checkpoint Blockade or Agonist Anti-OX40 Immunotherapy to Control Tumor Growth

M. V. Vander Heiden, C. Daige, J. Wiggins, 2021, Cancer Immunology Research.

Preclinical safety and antitumor activity of the arginine-degrading therapeutic enzyme pegzilarginase, a PEGylated, cobalt-substituted recombinant human arginase 1.

Giulia Agnello, S. Rowlinson, S. Alters, 2019, Translational research : the journal of laboratory and clinical medicine.

The first disulphide loop of the rabbit growth hormone receptor is required for binding to the hormone.

J. Mattick, M. Waters, S. Rowlinson, 1992, Journal of molecular endocrinology.

A novel mutation affecting the interdomain link region of the growth hormone receptor in a Vietnamese girl, and response to long-term treatment with recombinant human insulin-like growth factor-I and luteinizing hormone-releasing hormone analogue.

M. Waters, P. Crock, S. Rowlinson, 1998, The Journal of clinical endocrinology and metabolism.

A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology

L. Ricci-Vitiani, R. Pallini, M. Todaro, 2015, PloS one.

Prospects for a small molecule able to induce somatic growth through the growth hormone receptor

C. M. Chen, M. Waters, B. Conway-Campbell, 2006, Letters in Peptide Science.

Human growth hormone fragments 1-43 and 44-191: in vitro somatogenic activity and receptor binding characteristics in human and nonprimate systems.

M. Waters, U. Lewis, S. Rowlinson, 1996, Endocrinology.

Aspartate 171 Is the Major Primate-specific Determinant of Human Growth Hormone

M. Waters, B. Conway-Campbell, S. Rowlinson, 1997, The Journal of Biological Chemistry.

Structural insights into the stereochemistry of the cyclooxygenase reaction

Lawrence J. Marnett, James R. Kiefer, Ravi G. Kurumbail, 2000, Nature.

Action at a Distance

Anna L. Blobaum, L. Marnett, Shu Xu, 2015, The Journal of Biological Chemistry.

Characterization of the lysyl adducts of prostaglandin H-synthases that are derived from oxygenation of arachidonic acid.

P. Chaurand, R. Caprioli, O. Boutaud, 2001, Biochemistry.

Mechanism of inhibition of novel COX-2 inhibitors.

R. Kurumbail, L. Marnett, J. Gierse, 2002, Advances in experimental medicine and biology.

An electrostatic model for the interaction between growth hormone and its receptor involving chelation of Ca2+ to the human growth hormone molecule.

M. Waters, S. Rowlinson, R. Barnard, 1989, Journal of theoretical biology.

The Binding of Arachidonic Acid in the Cyclooxygenase Active Site of Mouse Prostaglandin Endoperoxide Synthase-2 (COX-2)

L. Marnett, S. Rowlinson, B. Crews, 1999, The Journal of Biological Chemistry.

A novel bioassay for human somatogenic activity in serum samples supports the clinical reliability of immunoassays

M. Waters, A. Cotterill, S. Rowlinson, 2002, Clinical endocrinology.

Enantiospecific, selective cyclooxygenase-2 inhibitors.

Lawrence J Marnett, L. Marnett, K. Kozak, 2002, Bioorganic & medicinal chemistry letters.

Abstract 3073: Targeting chronic lymphocytic leukemia by interfering glutathione synthesis using a novel therapeutic enzyme cyst(e)inase (AEB3103)

Peng Huang, M. Keating, E. Stone, 2016 .

Functional analysis of the molecular determinants of cyclooxygenase-2 acetylation by 2-acetoxyphenylhept-2-ynyl sulfide.

R. Caprioli, L. Marnett, J. F. Nemeth-Cawley, 2003, Archives of biochemistry and biophysics.

Tyrosine-385 Is Critical for Acetylation of Cyclooxygenase-2 by Aspirin

L. Marnett, S. Rowlinson, G. Hochgesang, 2000 .

Tyrosine-385 Is Critical for Acetylation of Cyclooxygenase-2 by Aspirin

L. Marnett, S. Rowlinson, G. Hochgesang, 2000 .

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Charles J. Vaske, Joe Y. Chang, Scott R. Presnell, 2016, Journal for ImmunoTherapy of Cancer.