D. Simnica

发表

Avelumab and cetuximab in combination with FOLFOX in patients with previously untreated metastatic colorectal cancer (MCRC): Final results of the phase II AVETUX trial (AIO-KRK-0216).

C. Bokemeyer, A. Hinke, A. Stein, 2020 .

Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease

M. Addo, S. Ciesek, D. Sedding, 2020, Immunity.

High-Throughput Immunogenetics Reveals a Lack of Physiological T Cell Clusters in Patients With Autoimmune Cytopenias

N. Akyüz, A. Lohse, S. Schliffke, 2019, Front. Immunol..

Efficacy of Ipilimumab vs FOLFOX in Combination With Nivolumab and Trastuzumab in Patients With Previously Untreated ERBB2-Positive Esophagogastric Adenocarcinoma: The AIO INTEGA Randomized Clinical Trial.

S. Kubicka, A. Hinke, M. Sinn, 2022, JAMA oncology.

T cell receptor next-generation sequencing reveals cancer-associated repertoire metrics and reconstitution after chemotherapy in patients with hematological and solid tumors

N. Akyüz, S. Schliffke, K. Lamszus, 2019, Oncoimmunology.

Next‐Generation Immunosequencing Reveals Pathological T‐Cell Architecture in Autoimmune Hepatitis

A. Lohse, E. Willscher, C. Weiler-Normann, 2020, Hepatology.

HLA class I-associated expansion of TRBV11-2 T cells in Multisystem Inflammatory Syndrome in Children.

M. H. Cheng, I. Bahar, J. McCormick, 2021, The Journal of clinical investigation.

Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination

E. Hovig, G. Bounova, T. Clancy, 2022, Journal of translational medicine.

Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19

E. Willscher, N. Gagliani, S. Eisenmann, 2021, iScience.

Deep sequencing of bone marrow microenvironments of patients with del(5q) myelodysplastic syndrome reveals imprints of antigenic selection as well as generation of novel T-cell clusters as a response pattern to lenalidomide

D. Nowak, W. Hofmann, N. Akyüz, 2019, Haematologica.

PD-L1 Amino Acid Position 88 Represents a Hotspot for PD-L1 Stability With Relevance for PD-L1 Inhibition

V. Heinemann, S. Stintzing, M. Binder, 2022, Frontiers in Oncology.

Azacitidine-induced reconstitution of the bone marrow T cell repertoire is associated with superior survival in AML patients

E. Willscher, H. Al-Ali, C. Dierks, 2022, Blood cancer journal.

Homologous recombination repair deficient prostate cancer represents an immunologically distinct subtype

R. Koornstra, G. V. van Leenders, I. V. van Oort, 2022, Oncoimmunology.

Translational analysis and final efficacy of the AVETUX trial – Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer

B. Seliger, C. Bokemeyer, A. Hinke, 2022, Frontiers in Oncology.

SARS-CoV-2-specific antibody rearrangements in prepandemic immune repertoires of risk cohorts and patients with COVID-19

E. Willscher, M. Vehreschild, M. Binder, 2021 .

Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome

M. H. Cheng, I. Bahar, J. V. Van Eyk, 2020, bioRxiv.

Rapid Hypermutation B Cell Trajectory Recruits Previously Primed B Cells Upon Third SARS-Cov-2 mRNA Vaccination

D. Sedding, M. Gekle, E. Willscher, 2022, bioRxiv.

Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination

E. Hovig, G. Bounova, T. Clancy, 2022, Journal of translational medicine.

Inflammasome Signaling Regulates the Microbial–Neuroimmune Axis and Visceral Pain in Mice

J. Cryan, A. Fanning, S. Melgar, 2021, International journal of molecular sciences.

Responsiveness to Immune Checkpoint Inhibitors Is Associated With a Peripheral Blood T-Cell Signature in Metastatic Castration-Resistant Prostate Cancer

E. Willscher, M. Smits, I. V. van Oort, 2020 .

Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src family kinases as prognostic markers and potential targets

T. Clauditz, T. Lange, U. Schumacher, 2021, International journal of cancer.

Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts

S. Ciesek, D. Sedding, E. Willscher, 2021, Clinical & translational immunology.

PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer

B. Seliger, C. Bokemeyer, A. Hinke, 2021, Journal for ImmunoTherapy of Cancer.

SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2

M. Altfeld, S. Schliffke, B. Fehse, 2020, Leukemia.

Evolutionary clonal trajectories in nodular lymphocyte-predominant Hodgkin lymphoma with high risk of transformation

A. Rosenwald, W. Klapper, G. Ott, 2021, Haematologica.

Early relapse detection by monitoring of circulating cell-free DNA in patients with localized head and neck squamous cell carcinoma: A subgroup analysis of the multicenter randomized clinical trial IMSTAR-HN.

J. Doescher, S. Laban, M. Binder, 2022, Oral oncology.

Dietary-Induced Bacterial Metabolites Reduce Inflammation and Inflammation-Associated Cancer via Vitamin D Pathway

A. Clooney, A. Fanning, S. Melgar, 2023, International journal of molecular sciences.

Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21R110 chronic lymphocytic leukemia

C. Dierks, M. Binder, D. Simnica, 2022, Blood Cancer Journal.

Targeting the Mutational Landscape of Bystander Cells: Drug-Promoted Blood Cancer From High-Prevalence Pre-neoplasias in Patients on BRAF Inhibitors

A. Stein, H. Ittrich, M. Binder, 2020, Frontiers in Oncology.

SARS-CoV-2 specific antibody rearrangements in pre-pandemic immune repertoires of risk cohorts and COVID-19 patients.

D. Sedding, E. Willscher, M. Vehreschild, 2020, The Journal of clinical investigation.