Masayuki Fujinaga

发表

Synthesis and evaluation of 4-halogeno-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-[11C]methylbenzamide for imaging of metabotropic glutamate 1 receptor in melanoma.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015, Journal of medicinal chemistry.

Initial Human PET Studies of Metabotropic Glutamate Receptor Type 1 Ligand 11C-ITMM

Keiichi Oda, Kiichi Ishiwata, Kenji Ishii, 2013, The Journal of Nuclear Medicine.

Synthesis and Evaluation of Novel Radioligands Based on 3-[5-(Pyridin-2-yl)-2H-tetrazol-2-yl]benzonitrile for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor Subtype 5.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2016, Journal of medicinal chemistry.

Synthesis and evaluation of novel radioligands for positron emission tomography imaging of metabotropic glutamate receptor subtype 1 (mGluR1) in rodent brain.

Lin Xie, Kazunori Kawamura, Toshimitsu Fukumura, 2012, Journal of medicinal chemistry.

Radiosynthesis and preliminary evaluation of 4-[18F]fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as a new positron emission tomography ligand for metabotropic glutamate receptor subtype 1.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of 6-[1-(2-[(18)F]fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain.

Ming-Rong Zhang, J. Maeda, Tomoteru Yamasaki, 2011, Bioorganic & medicinal chemistry.

Improved Visualization and Specific Binding for Metabotropic Glutamate Receptor Subtype 1 (mGluR1) Using [11C]ITMM with Ultra-High Specific Activity in Small-Animal PET

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015, PloS one.

In vivo positron emission tomography imaging of mitochondrial abnormalities in a mouse model of tauopathy

Ming-Rong Zhang, T. Suhara, I. Aoki, 2020, Neurobiology of Aging.

Utilization of [11C]phosgene for radiosynthesis of N-(2-{3-[3,5-bis(trifluoromethyl)]phenyl[11C]ureido}ethyl)glycyrrhetinamide, an inhibitory agent for proteasome and kinase in tumors.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2012, Bioorganic & medicinal chemistry letters.

Radiosynthesis of three [11C]ureido-substituted benzenesulfonamides as PET probes for carbonic anhydrase IX in tumors.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2011, Bioorganic & medicinal chemistry letters.

In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies.

Lu Wang, Lin Xie, Mary Jo Ondrechen, 2018, Journal of medicinal chemistry.

[11C]phosgene: Synthesis and application for development of PET radiotracers.

Ming-Rong Zhang, T. Fukumura, Masayuki Fujinaga, 2020, Nuclear medicine and biology.

Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[11C]carboxylate.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2019, Bioorganic & medicinal chemistry.

A Facile Radiolabeling of [18F]FDPA via Spirocyclic Iodonium Ylides: Preliminary PET Imaging Studies in Preclinical Models of Neuroinflammation.

Steven H. Liang, Ming-Rong Zhang, K. Kumata, 2017, Journal of medicinal chemistry.

Synthesis and Preclinical Evaluation of Sulfonamido-based [11C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase

Lu Wang, Lin Xie, Steven H. Liang, 2016, Theranostics.

Identification and Development of a New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[11C]methoxyphenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2).

Steven H. Liang, Ming-Rong Zhang, D. Sheffler, 2020, Journal of medicinal chemistry.

3-(Cyclopropylmethyl)-7-((4-(4-[11C]methoxyphenyl)piperidin-1-yl)methyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine: Synthesis and Preliminary Evaluation for PET Imaging of Metabotropic Glutamate Receptor Subtype 2.

Ming-Rong Zhang, K. Kumata, Kuan Hu, 2020, Bioorganic & medicinal chemistry letters.

Radiosynthesis and evaluation of acetamidobenzoxazolone based radioligand [11C]N′-MPB for visualization of 18 kDa TSPO in brain

Ming-Rong Zhang, Tomoteru Yamasaki, A. Hatori, 2020 .

Synthesis and evaluation of 1-(cyclopropylmethyl)-4-(4-[11C]methoxyphenyl)-piperidin-1-yl-2-oxo-1,2-dihydropyridine-3-carbonitrile ([11C]CMDC) for PET imaging of metabotropic glutamate receptor 2 in the rat brain.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2017, Bioorganic & medicinal chemistry.

Development of a 18F-Labeled Radiotracer with Improved Brain Kinetics for Positron Emission Tomography Imaging of Translocator Protein (18 kDa) in Ischemic Brain and Glioma.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2017, Journal of medicinal chemistry.

Synthesis and evaluation of new (18)F-labelled acetamidobenzoxazolone-based radioligands for imaging of the translocator protein (18 kDa, TSPO) in the brain.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, Organic & biomolecular chemistry.

Characterization of a novel acetamidobenzoxazolone‐based PET ligand for translocator protein (18 kDa) imaging of neuroinflammation in the brain

Ming-Rong Zhang, J. Maeda, Lin Xie, 2014, Journal of neurochemistry.

Automated radiosynthesis of two 18F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [18F]FMISO and [18F]PM-PBB3, via [18F]epifluorohydrin

Ming-Rong Zhang, K. Kawamura, K. Kumata, 2021, EJNMMI Radiopharmacy and Chemistry.

Radiosynthesis of 18F-fluoroethylated tracers via a simplified one-pot 18F-fluoroethylation method using [18F]fluoroethyl tosylate.

Ming-Rong Zhang, K. Kawamura, K. Kumata, 2020, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2018, Organic & biomolecular chemistry.

Comparison between [18F]fluorination and [18F]fluoroethylation reactions for the synthesis of the PDE10A PET radiotracer [18F]MNI-659.

Ming-Rong Zhang, M. Higuchi, K. Kawamura, 2017, Nuclear medicine and biology.

[18F]FEBMP: Positron Emission Tomography Imaging of TSPO in a Model of Neuroinflammation in Rats, and in vitro Autoradiograms of the Human Brain

Ming-Rong Zhang, J. Maeda, M. Higuchi, 2015, Theranostics.

[18F]FPBMP: – a potential new positron emission tomography radioligand for imaging of translocator protein (18 kDa) in peripheral organs of rats

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015 .

PET Imaging of Lung Inflammation with [18F]FEDAC, a Radioligand for Translocator Protein (18 kDa)

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2012, PloS one.

PET brain kinetics studies of (11)C-ITMM and (11)C-ITDM,radioprobes for metabotropic glutamate receptor type 1, in a nonhuman primate.

Lin Xie, Yuji Nagai, Joji Yui, 2014, American journal of nuclear medicine and molecular imaging.

Binding potential of (E)-[¹¹C]ABP688 to metabotropic glutamate receptor subtype 5 is decreased by the inclusion of its ¹¹C-labelled Z-isomer.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, Nuclear medicine and biology.

Evaluation of the novel TSPO radiotracer 2-(7-butyl-2-(4-(2-([18F]fluoroethoxy)phenyl)-5-methylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide in a preclinical model of neuroinflammation.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2018, European journal of medicinal chemistry.

Synthesis, metabolite analysis, and in vivo evaluation of [(11)C]irinotecan as a novel positron emission tomography (PET) probe.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2013, Nuclear medicine and biology.

Design, synthesis and biological evaluation of small molecule-based PET radioligands for the 5-hydroxytryptamine 7 receptor

Pooja, Ming-Rong Zhang, Lin Xie, 2015 .

Synthesis and evaluation of [11C]MMPIP as a potential radioligand for imaging of metabotropic glutamate 7 receptor in the brain

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2013, EJNMMI Research.

Monitoring Neuroprotective Effects Using Positron Emission Tomography With [11C]ITMM, a Radiotracer for Metabotropic Glutamate 1 Receptor

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2013, Stroke.

Radiosynthesis and in vivo Evaluation of Carbon‐11 (2S)‐3‐(1H‐Indol‐3‐yl)‐2‐{[(4‐methoxyphenyl)carbamoyl]amino}‐N‐{[1‐(5‐methoxypyridin‐2‐yl)cyclohexyl]methyl}propanamide: An Attempt to Visualize Brain Formyl Peptide Receptors in Mouse Models of Neuroinflammation

Ming-Rong Zhang, T. Suhara, E. Lacivita, 2016, Chemistry & biodiversity.

A novel monoacylglycerol lipase-targeted 18F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2022, Acta Pharmacologica Sinica.

Radiosynthesis and evaluation of 4-(6-[18F]Fluoro-4-(5-isopropoxy-1H-indazol-3-yl)pyridin-2-yl)morpholine as a novel radiotracer candidate targeting leucine-rich repeat kinase 2.

Ming-Rong Zhang, Tomoteru Yamasaki, K. Kumata, 2020, RSC medicinal chemistry.

Radiosynthesis and in vivo evaluation of 11C-labeled BMS-193885 and its desmethyl analog as PET tracers for neuropeptide Y1 receptors

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2019, EJNMMI Radiopharmacy and Chemistry.

Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-Indole Derivatives as a Novel Positron Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain.

Ming-Rong Zhang, T. Ohashi, Tomoteru Yamasaki, 2021, Journal of medicinal chemistry.

[18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18 kDa).

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2018, Bioorganic & medicinal chemistry.

A useful PET probe [11C]BU99008 with ultra-high specific radioactivity for small animal PET imaging of I2-imidazoline receptors in the hypothalamus.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2017, Nuclear medicine and biology.

Radiosynthesis and preliminary PET evaluation of glycogen synthase kinase 3β (GSK-3β) inhibitors containing [(11)C]methylsulfanyl, [(11)C]methylsulfinyl or [(11)C]methylsulfonyl groups.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Evaluation of (4 R)-1-{3-[2-(18F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one ([18F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase.

Ming-Rong Zhang, J. Maeda, Yuji Nagai, 2019, Journal of medicinal chemistry.

Imaging of Transmembrane AMPA Receptor Regulatory Proteins by Positron Emission Tomography.

Steven H. Liang, S. Tomita, Ming-Rong Zhang, 2022, Journal of medicinal chemistry.

Development of [(11)C]MFTC for PET imaging of fatty acid amide hydrolase in rat and monkey brains.

Ming-Rong Zhang, J. Maeda, Yuji Nagai, 2015, ACS chemical neuroscience.

[11C]sorafenib: radiosynthesis and preliminary PET study of brain uptake in P-gp/Bcrp knockout mice.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2011, Bioorganic & medicinal chemistry letters.

Radiosynthesis and evaluation of new PET ligands for peripheral cannabinoid receptor type 1 imaging.

Ming-Rong Zhang, Tomoteru Yamasaki, Masayuki Fujinaga, 2017, Bioorganic & medicinal chemistry letters.

Radiosynthesis and evaluation of N-(3,4-dimethylisoxazol-5-yl)piperazine-4-[4-(4-fluorophenyl)thiazol-2-yl]-1-[11C]carboxamide for in vivo positron emission tomography imaging of fatty acid amide hydrolase in brain

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015 .

TASP0434299: A Novel Pyridopyrimidin-4-One Derivative as a Radioligand for Vasopressin V1B Receptor

Ming-Rong Zhang, S. Chaki, T. Suhara, 2016, The Journal of Pharmacology and Experimental Therapeutics.

TASP 0434299 : A Novel Pyridopyrimidin-4-One Derivative as a Radioligand for Vasopressin V 1 B Receptor

Ming-Rong Zhang, S. Chaki, T. Suhara, 2016 .

Developing new PET tracers to image the growth hormone secretagogue receptor 1a (GHS-R1a).

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2017, Nuclear medicine and biology.

Synthesis and evaluation of 4-(2-fluoro-4-[11C]methoxyphenyl)-5-((2-methylpyridin-4-yl)methoxy)picolinamide for PET imaging of the metabotropic glutamate receptor 2 in the rat brain.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2019, Bioorganic & medicinal chemistry.

Identification and Development of A New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[ 11 C]methoxyphenyl)-5-((1-methyl-1 H -pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu 2 )

Steven H. Liang, Ming-Rong Zhang, D. Sheffler, 2021 .

Radiosynthesis of novel carbon-11-labeled triaryl ligands for cannabinoid-type 2 receptor.

Ming-Rong Zhang, J. Maeda, Tomoteru Yamasaki, 2010, Bioorganic & medicinal chemistry letters.

Change in the Binding of [11C]BU99008 to Imidazoline I2 Receptor Using Brain PET in Zucker Rats

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2019, Molecular Imaging and Biology.

In vivo evaluation of a new ¹⁸F-labeled PET ligand, [¹⁸F]FEBU, for the imaging of I₂-imidazoline receptors.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015, Nuclear medicine and biology.

Synthesis and evaluation of PET probes for the imaging of I2 imidazoline receptors in peripheral tissues.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2012, Nuclear medicine and biology.

imaging of I 2 -imidazoline receptors

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015 .

Development of an In Vivo Method to Estimate Effective Drug Doses and Quantify Fatty Acid Amide Hydrolase in Rodent Brain using Positron Emission Tomography Tracer [11C]DFMC

Ming-Rong Zhang, Tomoteru Yamasaki, Masayuki Fujinaga, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Synthesis and preliminary evaluation of a 11C-labeled piperidin-4-yl azetidine diamide for imaging monoacylglycerol lipase

Steven H. Liang, Ming-Rong Zhang, Joji Yui, 2016 .

Evaluation of Rho-Kinase Activity in Mice Brain Using N-[11C]Methyl-hydroxyfasudil with Positron Emission Tomography

I. Kanno, Ming-Rong Zhang, Hiroshi Ito, 2014, Molecular Imaging and Biology.

131I-IITM and 211At-AITM: Two Novel Small-Molecule Radiopharmaceuticals Targeting Oncoprotein Metabotropic Glutamate Receptor 1

Ming-Rong Zhang, Lin Xie, Kuan Hu, 2020, The Journal of Nuclear Medicine.

Synthesis and evaluation of 1-[2-(4-[(11)C]methoxyphenyl)phenyl]piperazine for imaging of the serotonin 5-HT7 receptor in the rat brain.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2013, Bioorganic & medicinal chemistry.

PET study using [11C]FTIMD with ultra-high specific activity to evaluate I2-imidazoline receptors binding in rat brains.

Ming-Rong Zhang, Y. Kimura, Tomoteru Yamasaki, 2012, Nuclear medicine and biology.

Scandium Triflate-Catalyzed N-[18F]Fluoroalkylation of Aryl- Or Heteroaryl-Amines with [18F]Epifluorohydrin under Mild Conditions.

Ming-Rong Zhang, Tomoteru Yamasaki, K. Kumata, 2022, Organic letters.

Visualization of Acute Liver Damage Induced by Cycloheximide in Rats Using PET with [18F]FEDAC, a Radiotracer for Translocator Protein (18 kDa)

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, PloS one.

Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[11C]methoxyphenethyl)pyridazin-3(2H)-one, a 11C-labeled d-amino acid oxidase (DAAO) inhibitor for PET imaging.

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2020, Bioorganic & medicinal chemistry letters.

Synthesis and preliminary evaluation of 18F-labeled 1-(6,7-dimethyl-4-(methylamino)-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)-2-(trans-2-(6-fluoropyridin-3-yl)cyclopropyl)ethan-1-one for imaging muscarinic acetylcholine receptor subtype 4

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2020 .

Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe 18F‐FITM

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, International journal of cancer.

Evaluation of the P-glycoprotein- and breast cancer resistance protein-mediated brain penetration of 11C-labeled topotecan using small-animal positron emission tomography.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2011, Nuclear medicine and biology.

Pharmacokinetic Evaluation of [11C]CEP-32496 in Nude Mice Bearing BRAFV600E Mutation-Induced Melanomas

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2018, Molecular imaging.

Radiosynthesis of [13N]dantrolene, a positron emission tomography probe for breast cancer resistant protein, using no-carrier-added [13N]ammonia.

Ming-Rong Zhang, Kazutoshi Suzuki, K. Kumata, 2012, Bioorganic & medicinal chemistry.

Imaging α-synuclein pathologies in animal models and patients with Parkinson’s and related diseases

Ming-Rong Zhang, A. Kakita, M. Ichise, 2020, bioRxiv.

[(11)C-carbonyl]CEP-32496: radiosynthesis, biodistribution and PET study of brain uptake in P-gp/BCRP knockout mice.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, Bioorganic & medicinal chemistry letters.

Development of 1-N-11C-Methyl-l- and -d-Tryptophan for pharmacokinetic imaging of the immune checkpoint inhibitor 1-Methyl-Tryptophan

Ming-Rong Zhang, T. Suhara, J. Maeda, 2015, Scientific Reports.

Automated Synthesis of (rac)‐, (R)‐, and (S)‐[18F]Epifluorohydrin and Their Application for Developing PET Radiotracers Containing a 3‐[18F]Fluoro‐2‐hydroxypropyl Moiety

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2018, ChemMedChem.

Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2021, Acta pharmaceutica Sinica. B.

Design, Synthesis and Evaluation of 18F-labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes.

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2019, Journal of medicinal chemistry.

Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on α-Ketoheterocyclic Scaffold.

Steven H. Liang, Ming-Rong Zhang, Tomoteru Yamasaki, 2016, ACS chemical neuroscience.

Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton.

Steven H. Liang, L. Josephson, Ming-Rong Zhang, 2019, Journal of medicinal chemistry.

Upregulation of Striatal Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Rats with Excessive Glutamate Release Induced by N-Acetylcysteine

Ming-Rong Zhang, Tomoteru Yamasaki, Masayuki Fujinaga, 2022, Neurotoxicity Research.

Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study

Lin Xie, Satoshi Shiomi, Hidekatsu Wakizaka, 2016, The Journal of Neuroscience.

Development of an In Vivo Method to Estimate Effective Drug Doses and Quantify Fatty Acid Amide Hydrolase in Rodent Brain using Positron Emission Tomography Tracer [11C]DFMC

Ming-Rong Zhang, Tomoteru Yamasaki, Masayuki Fujinaga, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Radiosynthesis and preclinical evaluation of a carbon-11 labeled PDE7 inhibitor for PET neuroimaging

Steven H. Liang, E. Leon, Ming-Rong Zhang, 2021, bioRxiv.

Preclinical and the first clinical studies on [11C]ITMM for mapping metabotropic glutamate receptor subtype 1 by positron emission tomography.

Keiichi Oda, Kiichi Ishiwata, Kenji Ishii, 2013, Nuclear medicine and biology.

Synthesis, pharmacology and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein.

Steven H. Liang, Patrick J. Dunn, S. Tomita, 2018, European journal of medicinal chemistry.

Synthesis and in vitro evaluation of three novel radiotracers for imaging of metabotropic glutamate receptor subtype 2 in rat brain.

Lin Xie, Tomoteru Yamasaki, K. Kumata, 2017, Bioorganic & medicinal chemistry letters.

Detection of Alzheimer’s disease-related neuroinflammation by a PET ligand selective for glial versus vascular translocator protein

T. Suhara, I. Aoki, M. Higuchi, 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Noninvasive Quantification of Metabotropic Glutamate Receptor Type 1 with [11C]ITDM: a Small-Animal PET Study

Lin Xie, Hidekatsu Wakizaka, Kazunori Kawamura, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Visualization of early infarction in rat brain after ischemia using a translocator protein (18kDa) PET ligand [11C]DAC with ultra-high specific activity

Yuichiro Yoshida, Kazutoshi Suzuki, Kazunori Kawamura, 2011, NeuroImage.

Translocator protein (18 kDa), a potential molecular imaging biomarker for non-invasively distinguishing non-alcoholic fatty liver disease.

Lin Xie, Tomoteru Yamasaki, Joji Yui, 2012, Journal of hepatology.

In vivo imaging and quantitative analysis of TSPO in rat peripheral tissues using small-animal PET with [18F]FEDAC.

O. Inoue, Tomoteru Yamasaki, Joji Yui, 2010, Nuclear medicine and biology.

N-(3,4-Dimethylisoxazol-5-yl)piperazine-4-[4-(2-fluoro-4-[(11)C]methylphenyl)thiazol-2-yl]-1-carboxamide: A promising positron emission tomography ligand for fatty acid amide hydrolase.

Lin Xie, Tomoteru Yamasaki, Joji Yui, 2016, Bioorganic & medicinal chemistry.

PET imaging of colony-stimulating factor 1 receptor: A head-to-head comparison of a novel radioligand, 11C-GW2580, and 11C-CPPC, in mouse models of acute and chronic neuroinflammation and a rhesus monkey

T. Suhara, T. Minamimoto, Yuji Nagai, 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

CENP‐C unwraps the human CENP‐A nucleosome through the H2A C‐terminal tail

Ingmar B. Schäfer, T. Suhara, T. Minamimoto, 2019, EMBO reports.

Genetically targeted reporter imaging of deep neuronal network in the mammalian brain

T. Suhara, T. Minamimoto, J. Maeda, 2020, bioRxiv.

Synthesis and biological evaluation of novel radioiodinated imidazopyridine derivatives for amyloid-β imaging in Alzheimer's disease.

T. Suhara, H. Shiraishi, M. Higuchi, 2014, Bioorganic & medicinal chemistry.

Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators

Steven H. Liang, L. Josephson, Lin Xie, 2020, Acta Pharmacologica Sinica.

Development of 2-(2-(3-(4-([18F]Fluoromethoxy- d2)phenyl)-7-methyl-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-4-isopropoxyisoindoline-1,3-dione for Positron-Emission-Tomography Imaging of Phosphodiesterase 10A in the Brain.

Lin Xie, Tomoteru Yamasaki, K. Kumata, 2018, Journal of medicinal chemistry.

Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators

Steven H. Liang, L. Josephson, Lin Xie, 2020, Acta Pharmacologica Sinica.