Jonathan J. Sabbagh

发表

Alzheimer's disease biomarkers: Correspondence between human studies and animal models

Jefferson W. Kinney, Jeffrey L. Cummings, J. Cummings, 2013, Neurobiology of Disease.

Alzheimer's disease biomarkers in animal models: closing the translational gap.

J. Cummings, J. Kinney, Jonathan J. Sabbagh, 2013, American journal of neurodegenerative disease.

Examination of ketamine-induced deficits in sensorimotor gating and spatial learning

J. Kinney, Chelcie F. Heaney, Jonathan J. Sabbagh, 2012, Physiology and Behavior.

Cellular factors modulating the mechanism of tau protein aggregation

C. Dickey, April L Darling, Jonathan J. Sabbagh, 2015, Cellular and Molecular Life Sciences.

Human cyclophilin 40 unravels neurotoxic amyloids

V. Uversky, E. Mandelkow, S. Becker, 2017, PLoS biology.

Targeting Hsp90 and its co-chaperones to treat Alzheimer’s disease

C. Dickey, Jonathan J. Sabbagh, L. Blair, 2014, Expert opinion on therapeutic targets.

Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement*

E. Zuiderweg, J. Gestwicki, S. Stevens, 2015, The Journal of Biological Chemistry.

MicroRNA-511 Binds to FKBP5 mRNA, Which Encodes a Chaperone Protein, and Regulates Neuronal Differentiation*

D. Zheng, C. Dickey, April L Darling, 2016, The Journal of Biological Chemistry.

The Metamorphic Nature of the Tau Protein: Dynamic Flexibility Comes at a Cost

C. Dickey, Jonathan J. Sabbagh, 2016, Front. Neurosci..

DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins

D. Zheng, S. Stevens, C. Dickey, 2016, The EMBO journal.

Drunk gamblers : the impact of legalized gambling on alcohol consumption

Jonathan J. Sabbagh, 2011 .

Noncontact Rotational Head Injury Produces Transient Cognitive Deficits but Lasting Neuropathological Changes.

J. Lloyd, C. Dickey, Jonathan J. Sabbagh, 2016, Journal of neurotrauma.

Postnatal alterations in GABAB receptor tone produce sensorimotor gating deficits and protein level differences in adulthood

J. Kinney, Chelcie F. Heaney, Jonathan J. Sabbagh, 2015, International Journal of Developmental Neuroscience.

Baclofen administration alters fear extinction and GABAergic protein levels

J. Kinney, Chelcie F. Heaney, Jonathan J. Sabbagh, 2012, Neurobiology of Learning and Memory.

Donepezil and galanin interactions in an animal model of Alzheimer’s disease

Jonathan J. Sabbagh, 2010 .

Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats

J. Kinney, Chelcie F. Heaney, Jonathan J. Sabbagh, 2016, Neuropharmacology.

Hsp90 activator Aha1 drives production of pathological tau aggregates

B. Blagg, J. Koren, D. Zheng, 2017, Proceedings of the National Academy of Sciences.

The effects of chronic calcium dysregulation on behavioral and pathological features of Alzheimer's disease

Jonathan J. Sabbagh, 2013 .

Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD.

J. Buchner, D. Rutz, J. Koren, 2018, ACS chemical biology.

Chronic ketamine produces altered distribution of parvalbumin-positive cells in the hippocampus of adult rats

J. Kinney, Chelcie F. Heaney, Jonathan J. Sabbagh, 2013, Neuroscience Letters.

Deficits in emotional learning and memory in an animal model of schizophrenia

J. Kinney, Chelcie F. Heaney, Jonathan J. Sabbagh, 2012, Behavioural Brain Research.

Animal systems in the development of treatments for Alzheimer's disease: challenges, methods, and implications

J. Cummings, J. Kinney, Jonathan J. Sabbagh, 2013, Neurobiology of Aging.

The emerging role of peptidyl‐prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease

C. Dickey, Jonathan J. Sabbagh, L. Blair, 2015, Journal of neurochemistry.

Torpor Does Not Influence Spatial Memory in Hibernating Golden-Mantled Ground Squirrels (Spermophilus [Callospermophilus] lateralis)

F. van Breukelen, J. Kinney, Chelcie F. Heaney, 2022, Physiological and Biochemical Zoology.

Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

C. Dickey, Jonathan J. Sabbagh, M. Selenica, 2015, Acta neuropathologica communications.

Administration of Donepezil Does Not Rescue Galanin-Induced Spatial Learning Deficits

J. Kinney, Chelcie F. Heaney, Jonathan J. Sabbagh, 2012, The International journal of neuroscience.

Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency

E. Binder, T. Klengel, C. Dickey, 2014, PloS one.

Cellular factors modulating the mechanism of tau protein aggregation

C. Dickey, April L Darling, Jonathan J. Sabbagh, 2015, Cellular and Molecular Life Sciences.

Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules.

T. Haystead, J. Gestwicki, D. Zheng, 2016, ACS chemical biology.

Hippocampal Neurogenesis Is Enhanced in Adult Tau Deficient Mice

C. Dickey, Jonathan J. Sabbagh, L. Blair, 2020, Cells.

The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics.

J. Gestwicki, S. Borysov, M. Zweckstetter, 2015, Human molecular genetics.

Targeting the ER-autophagy system in the trabecular meshwork to treat glaucoma.

C. Dickey, Jonathan J. Sabbagh, Sarah N. Fontaine, 2016, Experimental eye research.