G. Holtz

发表

Reductions in beta-amyloid concentrations in vivo by the gamma-secretase inhibitors BMS-289948 and BMS-299897.

S. Wagner, B. Lamb, D. Barten, 2005, Biochemical pharmacology.

3-[3-Fluoro-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)phenyl]-4-methylpyridine: a highly potent and orally bioavailable metabotropic glutamate subtype 5 (mGlu5) receptor antagonist.

N. Cosford, Merryl D. Cramer, Nicholas D Smith, 2004, Bioorganic & medicinal chemistry letters.

[3H]Methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine Binding to Metabotropic Glutamate Receptor Subtype 5 in Rodent Brain: In Vitro and in Vivo Characterization

Nicholas D. P. Cosford, N. Cosford, M. Bradbury, 2002, Journal of Pharmacology and Experimental Therapeutics.

3‐[3‐Fluoro‐5‐(5‐pyridin‐2‐yl‐2H‐tetrazol‐2‐yl)phenyl] ‐4‐methylpyridine: A Highly Potent and Orally Bioavailable Metabotropic Glutamate Subtype 5 (mGlu5) Receptor Antagonist.

N. Cosford, Merryl D. Cramer, G. Holtz, 2005 .

Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice.

D. Borchelt, D. Price, P. Wong, 2001, Human molecular genetics.

Reduced cerebrospinal fluid levels of α-secretase-cleaved amyloid precursor protein in aged rats: correlation with spatial memory deficits

S. Wagner, F. Menzaghi, R. Wang, 1999, Neuroscience.

Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.

D. Price, S. Younkin, S. Wagner, 1997, Human molecular genetics.

Reductions in β-amyloid concentrations in vivo by the γ-secretase inhibitors BMS-289948 and BMS-299897

S. Wagner, B. Lamb, D. Barten, 2005 .

Metabotropic glutamate receptor 5 antagonist-induced stimulation of hypothalamic–pituitary–adrenal axis activity: interaction with serotonergic systems

M. Bradbury, H. Schaffhauser, G. Holtz, 2003, Neuropharmacology.

Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice

S. Wagner, S. Sisodia, Jeffrey Anderson, 1999, Nature Neuroscience.

In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine).

N. Cosford, M. Bradbury, Jeffery J. Anderson, 2003, European journal of pharmacology.